The critical roles of COUP-TFII in tumor progression and metastasis

Cell and Bioscience

Volumn 4, Issue 1, 2014, Pages

  Qin, Jun ^a,b,c   Tsai, Sophia Y ^c   Tsai, Ming Jer ^c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84927696992     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-4-58     Document Type: Review

References (37)

1. Evans RM: The nuclear receptor superfamily: a rosetta stone for physiology. Mol Endocrinol 2005,19(6):1429-1438 10.1210/me.2005-0046.
2. Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ: Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 2006,126(4):789-799 10.1016/j.cell.2006.06.049.
3. Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ, O'Malley BW: COUP transcription factor is a member of the steroid receptor superfamily. Nature 1989,340(6229):163-166 10.1038/340163a0.
4. Tsai SY, Tsai MJ: Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev 1997,18(2):229-240.
5. Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY: Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest 2010,120(5):1694-1707 10.1172/JCI40101.
6. Qin J, Chen X, Xie X, Tsai MJ, Tsai SY: COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A 2010,107(8):3687-3692 10.1073/pnas.0914619107.
7. Tang K, Rubenstein JL, Tsai SY, Tsai MJ: COUP-TFII controls amygdala patterning by regulating neuropilin expression. Development 2012,139(9):1630-1639 10.1242/dev.075564.
8. Wu SP, Cheng CM, Lanz RB, Wang T, Respress JL, Ather S, Chen W, Tsai SJ, Wehrens XH, Tsai MJ, Tsai SY: Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell 2013,25(4):417-426 10.1016/j.devcel.2013.04.017.
9. Xie X, Qin J, Lin SH, Tsai SY, Tsai MJ: Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation. Proc Natl Acad Sci U S A 2011,108(36):14843-14848 10.1073/pnas.1110236108.
10. Xie X, Tang K, Yu CT, Tsai SY, Tsai MJ: Regulatory potential of COUP-TFs in development: stem/progenitor cells. Seminars in Cell and Dev Biol 2013,24(10-12):687-693.
11. Li L, Xie X, Qin J, Jeha GS, Saha PK, Yan J, Haueter CM, Chan L, Tsai SY, Tsai MJ: The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism. Cell Metab 2009,9(1):77-87 10.1016/j.cmet.2008.12.002.
12. You LR, Lin FJ, Lee CT, DeMayo FJ, Tsai MJ, Tsai SY: Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature 2005,435(7038):98-104. 10.1038/nature03511
13. Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, DeMayo FJ, Tsai MJ, Tsai SY: COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development 2005,132(9):2179-2189 10.1242/dev.01808.
14. Yu CT, Tang K, Suh JM, Jiang R, Tsai SY, Tsai MJ: COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. Development 2012,139(13):2330-2339 10.1242/dev.076299.
15. Pereira FA, Qiu Y, Zhou G, Tsai MJ, Tsai SY: The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev 1999,13(8):1037-1049 10.1101/gad.13.8.1037.
16. Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsia MJ, Tsai SY: COUP-TFII inhibits TGF-beta-induced growth barrier to promote prostate tumorigenesis. Nature 2013,493(7431):236-240.
17. Qin J, Tsai S, Tsai MJ: COUP-TFII, a prognostic marker and therapeutic target for prostate cancer. Asian J Androl 2013,15(3):360-361 10.1038/aja.2013.12.
18. Chen X, Qin J, Cheng CM, Tsai MJ, Tsai SY: COUP-TFII is a major regulator of cell cycle and Notch signaling pathways. Mol Endocrinol 2012,26(8):1268-1277 10.1210/me.2011-1305.
19. Qin J, Chen X, Yu-Lee LY, Tsai MJ, Tsai SY: Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res 2010,70(21):8812-8821 10.1158/0008-5472.CAN-10-0551.
20. Lin FJ, Qin J, Tang K, Tsai SY, Tsai MJ: Coup d'Etat: an orphan takes control. Endocr Rev 2011,32(3):404-421 10.1210/er.2010-0021.
21. Carmeliet P, Jain RK: Angiogenesis in cancer and other diseases. Nature 2000,407(6801):249-257 10.1038/35025220.
22. Siekmann AF, Lawson ND: Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 2007,445(7129):781-784 10.1038/nature05577.
23. Hellstrom M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalen M, Gerhardt H, Betsholtz C: Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 2007,445(7129):776-780 10.1038/nature05571.
24. Noguera-Troise I, Daly C, Papadopoulos NJ, Coetzee S, Boland P, Gale NW, Lin HC, Yancopoulos GD, Thurston G: Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature 2006,444(7122):1032-1037 10.1038/nature05355.
25. Nagasaki S, Suzuki T, Miki Y, Akahira J, Shibata H, Ishida T, Ohuchi N, Sasano H: Chicken ovalbumin upstream promoter transcription factor II in human breast carcinoma: possible regulator of lymphangiogenesis via vascular endothelial growth factor-C expression. Cancer Sci 2009,100(4):639-645 10.1111/j.1349-7006.2008.01078.x.
26. Litchfield LM, Riggs KA, Hockenberry AM, Oliver LD, Barnhart KG, Cai J, Pierce WM Jr, Ivanova MM, Bates PJ, Appana SN, Datta S, Kulesza P, McBryan J, Young LS, Klinge CM: Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor beta transcription in breast cancer cells. PLoS One 2012,7(5):e38278 10.1371/journal.pone.0038278.
27. Polvani S, Tarocchi M, Tempesti S, Mello T, Ceni E, Buccoliero F, D'Amico M, Boddi V, Farsi M, Nesi S, Nesi G, Milani S, Galli A: COUP-TFII in pancreatic adenocarcinoma: clinical implication for patient survival and tumor progression. Int J Cancer 2014,134(7):1648-1658 10.1002/ijc.28502.
28. Shin SW, Kwon HC, Rho MS, Choi HJ, Kwak JY, Park JI: Clinical significance of chicken ovalbumin upstream promoter-transcription factor II expression in human colorectal cancer. Oncol Rep 2009,21(1):101-106.
29. Safe S, Jin UH, Hedrick E, Reeder A, Lee SO: Minireview: role of orphan nuclear receptors in cancer and potential as drug targets. Mol Endocrinol 2014,28(2):157-172 10.1210/me.2013-1291.
30. Hawkins SM, Loomans HA, Wan YW, Ghosh-Choudhury T, Coffey D, Xiao W, Liu Z, Sangi-Haghpeykar H, Anderson ML: Expression and functional pathway analysis of nuclear receptor NR2F2 in ovarian cancer. J Clin Endocrinol Metab 2013,98(7):E1152-E1162 10.1210/jc.2013-1081.
31. Lee BC, Cha K, Avraham S, Avraham HK: Microarray analysis of differentially expressed genes associated with human ovarian cancer. Int J Oncol 2004,24(4):847-851.
32. Johnson DG, Schwarz JK, Cress WD, Nevins JR: Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 1993,365(6444):349-352 10.1038/365349a0.
33. Massague J, Blain SW, Lo RS: TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000,103(2):295-309 10.1016/S0092-8674(00)00121-5.
34. Riggs KA, Wickramasinghe NS, Cochrum RK, Watts MB, Klinge CM: Decreased chicken ovalbumin upstream promoter transcription factor II expression in tamoxifen-resistant breast cancer cells. Cancer Res 2006,66(20):10188-10198 10.1158/0008-5472.CAN-05-3937.
35. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov 2006,5(12):993-996 10.1038/nrd2199.
36. Kruse SW, Suino-Powell K, Zhou XE, Kretschman JE, Reynolds R, Vonrhein C, Xu Y, Wang L, Tsai SY, Tsai MJ, Xu HE: Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol 2008,6(9):e227 10.1371/journal.pbio.0060227.
37. Song CH, Lee HJ, Park E, Lee K: The chicken ovalbumin upstream promoter-transcription factor II negatively regulates the transactivation of androgen receptor in prostate cancer cells. PLoS One 2012,7(11):e49026 10.1371/journal.pone.0049026.