The Chicken Ovalbumin Upstream Promoter-Transcription Factor II Negatively Regulates the Transactivation of Androgen Receptor in Prostate Cancer Cells

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Song, Chin Hee ^a   Lee, Hyun Joo ^a   Park, Eunsook ^a   Lee, Keesook ^a  

^a Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; HISTONE DEACETYLASE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CANCER CELL; CARCINOGENESIS; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; COS CELLS; COUP TRANSCRIPTION FACTOR II; DNA-BINDING PROTEINS; MALE; MICE; PROMOTER REGIONS, GENETIC; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; RECEPTORS, ANDROGEN; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84868696968     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049026     Document Type: Article

References (56)

1. Gelmann EP, (2002) Molecular biology of the androgen receptor. J Clin Oncol 20: 3001-3015.
2. Cunha GR, Donjacour AA, Cooke PS, Mee S, Bigsby RM, et al. (1987) The endocrinology and developmental biology of the prostate. Endocr Rev 8: 338-362.
3. Marker PC, Donjacour AA, Dahiya R, Cunha GR, (2003) Hormonal, cellular, and molecular control of prostatic development. Dev Biol 253: 165-174.
4. Fujimoto N, Mizokami A, Harada S, Matsumoto T, (2001) Different expression of androgen receptor coactivators in human prostate. Urology 58: 289-294.
5. Davies P, Eaton CL, (1991) Regulation of prostate growth. J Endocrinol 131: 5-17.
6. Miyamoto H, Messing EM, Chang C, (2004) Androgen deprivation therapy for prostate cancer: current status and future prospects. Prostate 61: 332-353.
7. Heinlein CA, Chang C, (2004) Androgen receptor in prostate cancer. Endocr Rev 25: 276-308.
8. Tsai MJ, O'Malley BW, (1994) Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63: 451-486.
9. Langley E, Zhou ZX, Wilson EM, (1995) Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer. J Biol Chem 270: 29983-29990.
10. Wong CI, Zhou ZX, Sar M, Wilson EM, (1993) Steroid requirement for androgen receptor dimerization and DNA binding. Modulation by intramolecular interactions between the NH2-terminal and steroid-binding domains. J Biol Chem 268: 19004-19012.
11. Kim J, Coetzee GA, (2004) Prostate specific antigen gene regulation by androgen receptor. J Cell Biochem 93: 233-241.
12. Truss M, Bartsch J, Schelbert A, Hache RJ, Beato M, (1995) Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. EMBO J 14: 1737-1751.
13. Bannister AJ, Kouzarides T, (1996) The CBP co-activator is a histone acetyltransferase. Nature 384: 641-643.
14. Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y, (1996) The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87: 953-959.
15. Imhof A, Yang XJ, Ogryzko VV, Nakatani Y, Wolffe AP, et al. (1997) Acetylation of general transcription factors by histone acetyltransferases. Curr Biol 7: 689-692.
16. McKenna NJ, Lanz RB, O'Malley BW, (1999) Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev 20: 321-344.
17. Burd CJ, Morey LM, Knudsen KE, (2006) Androgen receptor corepressors and prostate cancer. Endocr Relat Cancer 13: 979-994.
18. Heemers HV, Tindall DJ, (2007) Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr Rev 28: 778-808.
19. Tsai SY, Tsai MJ, (1997) Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev 18: 229-240.
20. Pereira FA, Qiu Y, Tsai MJ, Tsai SY, (1995) Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis. J Steroid Biochem Mol Biol 53: 503-508.
21. Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, et al. (1994) Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A 91: 4451-4455.
22. Liu X, Huang X, Sigmund CD, (2003) Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription. Circ Res 92: 1033-1040.
23. Cooney AJ, Leng X, Tsai SY, O'Malley BW, Tsai MJ, (1993) Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem 268: 4152-4160.
24. Nakshatri H, Mendonca MS, Bhat-Nakshatri P, Patel NM, Goulet RJ Jr, et al. (2000) The orphan receptor COUP-TFII regulates G2/M progression of breast cancer cells by modulating the expression/activity of p21(WAF1/CIP1), cyclin D1, and cdk2. Biochem Biophys Res Commun 270: 1144-1153.
25. Sugiyama T, Wang JC, Scott DK, Granner DK, (2000) Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene. J Biol Chem 275: 3446-3454.
26. Lin F, Kolluri SK, Chen GQ, Zhang XK, (2002) Regulation of retinoic acid-induced inhibition of AP-1 activity by orphan receptor chicken ovalbumin upstream promoter-transcription factor. J Biol Chem 277: 21414-21422.
27. Klinge CM, Silver BF, Driscoll MD, Sathya G, Bambara RA, et al. (1997) Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression. J Biol Chem 272: 31465-31474.
28. Park JI, Tsai SY, Tsai MJ, (2003) Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions. Keio J Med 52: 174-181.
29. Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ, (1997) Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol 11: 714-724.
30. Leng X, Cooney AJ, Tsai SY, Tsai MJ, (1996) Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression. Mol Cell Biol 16: 2332-2340.
31. Achatz G, Holzl B, Speckmayer R, Hauser C, Sandhofer F, et al. (1997) Functional domains of the human orphan receptor ARP-1/COUP-TFII involved in active repression and transrepression. Mol Cell Biol 17: 4914-4932.
32. More E, Fellner T, Doppelmayr H, Hauser-Kronberger C, Dandachi N, et al. (2003) Activation of the MAP kinase pathway induces chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) expression in human breast cancer cell lines. J Endocrinol 176: 83-94.
33. Riggs KA, Wickramasinghe NS, Cochrum RK, Watts MB, Klinge CM, (2006) Decreased chicken ovalbumin upstream promoter transcription factor II expression in tamoxifen-resistant breast cancer cells. Cancer Res 66: 10188-10198.
34. Litchfield LM, Riggs KA, Hockenberry AM, Oliver LD, Barnhart KG, et al. (2012) Identification and Characterization of Nucleolin as a COUP-TFII Coactivator of Retinoic Acid Receptor beta Transcription in Breast Cancer Cells. PLoS One 7: e38278.
35. Shibata H, Ikeda Y, Morohashi K, Mukai T, Kurihara I, et al. (2000) Orphan receptors COUP-TF and DAX-1 as targets in disordered CYP17 expression in adrenocortical tumors. Endocr Res 26: 1039-1044.
36. Chen GQ, Lin B, Dawson MI, Zhang XK, (2002) Nicotine modulates the effects of retinoids on growth inhibition and RAR beta expression in lung cancer cells. Int J Cancer 99: 171-178.
37. Navab R, Gonzalez-Santos JM, Johnston MR, Liu J, Brodt P, et al. (2004) Expression of chicken ovalbumin upstream promoter-transcription factor II enhances invasiveness of human lung carcinoma cells. Cancer Res 64: 5097-5105.
38. Lee HJ, Hwang M, Chattopadhyay S, Choi HS, Lee K, (2008) Hepatocyte nuclear factor-3 alpha (HNF-3alpha) negatively regulates androgen receptor transactivation in prostate cancer cells. Biochem Biophys Res Commun 367: 481-486.
39. Langley E, Kemppainen JA, Wilson EM, (1998) Intermolecular NH2-/carboxyl-terminal interactions in androgen receptor dimerization revealed by mutations that cause androgen insensitivity. J Biol Chem 273: 92-101.
40. Qamar I, Park E, Gong EY, Lee HJ, Lee K, (2009) ARR19 (androgen receptor corepressor of 19 kDa), an antisteroidogenic factor, is regulated by GATA-1 in testicular Leydig cells. J Biol Chem 284: 18021-18032.
41. Jeong BC, Hong CY, Chattopadhyay S, Park JH, Gong EY, et al. (2004) Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase. Mol Endocrinol 18: 13-25.
42. Lee SY, Gong EY, Hong CY, Kim KH, Han JS, et al. (2009) ROS inhibit the expression of testicular steroidogenic enzyme genes via the suppression of Nur77 transactivation. Free Radic Biol Med 47: 1591-1600.
43. Suh JH, Shong M, Choi HS, Lee K, (2008) CR6-interacting factor 1 represses the transactivation of androgen receptor by direct interaction. Mol Endocrinol 22: 33-46.
44. Brothman AR, Lesho LJ, Somers KD, Schellhammer PF, Ladaga LE, et al. (1989) Cytogenetic analysis of four primary prostatic cultures. Cancer Genet Cytogenet 37: 241-248.
45. Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, et al. (1994) Inhibition of nuclear hormone receptor activity by calreticulin. Nature 367: 480-483.
46. Glozak MA, Sengupta N, Zhang X, Seto E, (2005) Acetylation and deacetylation of non-histone proteins. Gene 363: 15-23.
47. Fu M, Wang C, Reutens AT, Wang J, Angeletti RH, et al. (2000) p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. J Biol Chem 275: 20853-20860.
48. Gaughan L, Logan IR, Cook S, Neal DE, Robson CN, (2002) Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor. J Biol Chem 277: 25904-25913.
49. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ, (1992) Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol 12: 4153-4163.
50. Ladias JA, Hadzopoulou-Cladaras M, Kardassis D, Cardot P, Cheng J, et al. (1992) Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3. J Biol Chem 267: 15849-15860.
51. Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, et al. (2004) Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. J Biol Chem 279: 33438-33446.
52. Powell SM, Christiaens V, Voulgaraki D, Waxman J, Claessens F, et al. (2004) Mechanisms of androgen receptor signalling via steroid receptor coactivator-1 in prostate. Endocr Relat Cancer 11: 117-130.
53. Dubbink HJ, Hersmus R, Pike AC, Molier M, Brinkmann AO, et al. (2006) Androgen receptor ligand-binding domain interaction and nuclear receptor specificity of FXXLF and LXXLL motifs as determined by L/F swapping. Mol Endocrinol 20: 1742-1755.
54. Shen HC, Buchanan G, Butler LM, Prescott J, Henderson M, et al. (2005) GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor. Biol Chem 386: 69-74.
55. Fu M, Rao M, Wang C, Sakamaki T, Wang J, et al. (2003) Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Mol Cell Biol 23: 8563-8575.
56. Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, et al. (2003) Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 4: 223-238.