Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 3, 2014, Pages

  Fujisawa, Daisuke ^a   Kashiwakura, Jun Ichi ^b   Kita, Hirohito ^c   Kikukawa, Yusuke ^d   Fujitani, Yasushi ^d   Sasaki Sakamoto, Tomomi ^a   Kuroda, Kazumichi ^a   Nunomura, Satoshi ^a   Hayama, Koremasa ^a   Terui, Tadashi ^a   Ra, Chisei ^a   Okayama, Yoshimichi ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Institute of Physical and Chemical Research   (Japan)

^c Mayo Clinic College of Medicine   (United States)

^d Takeda Pharmaceutical Company   (Japan)

Author keywords

Chronic urticaria; eosinophil granule proteins; eosinophil peroxidase; eosinophils; histamine; human skin mast cells; major basic protein; Mas related gene X2; substance P

Indexed keywords

CALCIUM; EOSINOPHIL GRANULE PROTEIN; EOSINOPHIL PEROXIDASE; EOSINOPHIL PROTEIN X; HISTAMINE; MAJOR BASIC PROTEIN; MAS RELATED GENE X2 RECEPTOR; MESSENGER RNA; NEUROKININ 1 RECEPTOR; NEUROPEPTIDE RECEPTOR; PROSTAGLANDIN D2; SHORT HAIRPIN RNA; SUBSTANCE P; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; MRGPRX2 PROTEIN, HUMAN; NERVE PROTEIN; PROTEIN BINDING; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADULT; AGED; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ACTIVATION; CELL INFILTRATION; CELL SURFACE; CHO CELL LINE; CHRONIC URTICARIA; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOPLASM; DISEASE SEVERITY; DOWN REGULATION; ENZYME IMMUNOASSAY; EOSINOPHIL; FEMALE; GENE SILENCING; GENETIC TRANSFECTION; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALE; MAST CELL; MAST CELL DEGRANULATION; MIDDLE AGED; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN; UPREGULATION; YOUNG ADULT; CELL CULTURE; CHRONIC DISEASE; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; SKIN TEST; URTICARIA; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CELLS, CULTURED; CHRONIC DISEASE; EOSINOPHIL GRANULE PROTEINS; FEMALE; HUMANS; MALE; MAST CELLS; MIDDLE AGED; MOLECULAR TARGETED THERAPY; NERVE TISSUE PROTEINS; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; SKIN; SKIN TESTS; SUBSTANCE P; UP-REGULATION; URTICARIA; VASOACTIVE INTESTINAL PEPTIDE; YOUNG ADULT;

EID: 84927676812     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.05.004     Document Type: Article

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