Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor i and Fcγ receptor II

Arthritis and Rheumatism

Volumn 65, Issue 1, 2013, Pages 109-119

  Lee, Hyunho ^a   Kashiwakura, Jun Ichi ^a   Matsuda, Akira ^b   Watanabe, Yasuo ^b   Sakamoto Sasaki, Tomomi ^a   Matsumoto, Kenji ^c   Hashimoto, Noriko ^c   Saito, Shu ^a   Ohmori, Kazumitsu ^a   Nagaoka, Masahiro ^a   Tokuhashi, Yasuaki ^a   Ra, Chisei ^a   Okayama, Yoshimichi ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; FC RECEPTOR; FC RECEPTOR IIA; HISTAMINE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; STEM CELL FACTOR;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL ACTIVATION; CELL CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; JOINT PROSTHESIS; MAJOR CLINICAL STUDY; MAST CELL; OSTEOARTHRITIS; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM;

ARTHRITIS, RHEUMATOID; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; MAST CELLS; OSTEOARTHRITIS; RECEPTORS, IGG; SYNOVIAL MEMBRANE;

EID: 84871778491     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37741     Document Type: Article

References (49)

1. Harre U, Georgess D, Bang H, Bozec A, Axmann R, Ossipova E, et al. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J Clin Invest 2012; 122: 1791-802.
2. Monach PA, Mathis D, Benoist C,. The K/BxN arthritis model. Curr Protoc Immunol 2008;Chapter 15:Unit 15.22.
3. Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, et al. Arthritis critically dependent on innate immune system players. Immunity 2002; 16: 157-68.
4. Bruhns P, Samuelsson A, Pollard JW, Ravetch JV,. Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity 2003; 18: 573-81.
5. Van Lent PL, van Vuuren AJ, Blom AB, Holthuysen AE, van de Putte LB, van de Winkel JG, et al. Role of Fc receptor γ chain in inflammation and cartilage damage during experimental antigen-induced arthritis. Arthritis Rheum 2000; 43: 740-52.
6. Kleinau S, Martinsson P, Heyman B,. Induction and suppression of collagen-induced arthritis is dependent on distinct fcγ receptors. J Exp Med 2000; 191: 1611-6.
7. Kagari T, Tanaka D, Doi H, Shimozato T,. Essential role of Fc γ receptors in anti-type II collagen antibody-induced arthritis. J Immunol 2003; 170: 4318-24.
8. Lee DM, Friend DS, Gurish MF, Benoist C, Mathis D, Brenner MB,. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science 2002; 297: 1689-92.
9. Corr M, Crain B,. The role of FcγR signaling in the K/BxN serum transfer model of arthritis. J Immunol 2002; 169: 6604-9.
10. Nigrovic PA, Binstadt BA, Monach PA, Johnsen A, Gurish M, Iwakura Y, et al. Mast cells contribute to initiation of autoantibody- mediated arthritis via IL-1. Proc Natl Acad Sci U S A 2007; 104: 2325-30.
11. Guma M, Kashiwakura J, Crain B, Kawakami Y, Beutler B, Firestein GS, et al. JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis. Proc Natl Acad Sci U S A 2010; 107: 22122-7.
12. Zhou JS, Xing W, Friend DS, Austen KF, Katz HR,. Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis. J Exp Med 2007; 204: 2797-802.
13. Mancardi DA, Jonsson F, Iannascoli B, Khun H, Van Rooijen N, Huerre M, et al. Cutting edge: the murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis. J Immunol 2011; 186: 1899-903.
14. Feyerabend TB, Weiser A, Tietz A, Stassen M, Harris N, Kopf M, et al. Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity. Immunity 2011; 35: 832-44.
15. Shin K, Nigrovic PA, Crish J, Boilard E, McNeil HP, Larabee KS, et al. Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes. J Immunol 2009; 182: 647-56.
16. Crisp AJ, Chapman CM, Kirkham SE, Schiller AL, Krane SM,. Articular mastocytosis in rheumatoid arthritis. Arthritis Rheum 1984; 27: 845-51.
17. Malone DG, Irani AM, Schwartz LB, Barrett KE, Metcalfe DD,. Mast cell numbers and histamine levels in synovial fluids from patients with diverse arthritides. Arthritis Rheum 1986; 29: 956-63.
18. Tetlow LC, Woolley DE,. Mast cells, cytokines, and metalloproteinases at the rheumatoid lesion: dual immunolocalisation studies. Ann Rheum Dis 1995; 54: 896-903.
19. Eklund KK,. Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy. Immunol Rev 2007; 217: 38-52.
20. Nigrovic PA, Lee DM,. Synovial mast cells: role in acute and chronic arthritis. Immunol Rev 2007; 217: 19-37.
21. Sawamukai N, Yukawa S, Saito K, Nakayamada S, Kambayashi T, Tanaka Y,. Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling. Arthritis Rheum 2010; 62: 952-9.
22. Hueber AJ, Asquith DL, Miller AM, Reilly J, Kerr S, Leipe J, et al. Mast cells express IL-17A in rheumatoid arthritis synovium. J Immunol 2010; 184: 3336-40.
23. Kiener HP, Baghestanian M, Dominkus M, Walchshofer S, Ghannadan M, Willheim M, et al. Expression of the C5a receptor (CD88) on synovial mast cells in patients with rheumatoid arthritis. Arthritis Rheum 1998; 41: 233-45.
24. Okayama Y, Kirshenbaum AS, Metcalfe DD,. Expression of a functional high-affinity IgG receptor, FcγRI, on human mast cells: up-regulation by IFN-γ. J Immunol 2000; 164: 4332-9.
25. Okayama Y, Hagaman DD, Woolhiser M, Metcalfe DD,. Further characterization of FcγRII and FcγRIII expression by cultured human mast cells. Int Arch Allergy Immunol 2001; 124: 155-7.
26. Okayama Y, Hagaman DD, Metcalfe DD,. A comparison of mediators released or generated by IFN-γ-treated human mast cells following aggregation of FcγRI or FcεRI. J Immunol 2001; 166: 4705-12.
27. Woolhiser MR, Okayama Y, Gilfillan AM, Metcalfe DD,. IgG-dependent activation of human mast cells following up-regulation of FcγRI by IFN-γ. Eur J Immunol 2001; 31: 3298-307.
28. Okayama Y, Tkaczyk C, Metcalfe DD, Gilfillan AM,. Comparison of FcεRI- and FcγRI-mediated degranulation and TNF-α synthesis in human mast cells: selective utilization of phosphatidylinositol- 3-kinase for FcγRI-induced degranulation. Eur J Immunol 2003; 33: 1450-9.
29. Tkaczyk C, Okayama Y, Woolhiser M, Hagaman D, Gilfillan A, Metcalfe D,. Activation of human mast cells through the high affinity IgG receptor. Mol Immunol 2002; 38: 1289-93.
30. Kobayashi R, Okamura S, Ohno T, Saito H, Mori M, Ra C, et al. Hyperexpression of FcγRI and Toll-like receptor 4 in the intestinal mast cells of Crohn's disease patients. Clin Immunol 2007; 125: 149-58.
31. Kajiwara N, Sasaki T, Bradding P, Cruse G, Sagara H, Ohmori K, et al. Activation of human mast cells through the platelet-activating factor receptor. J Allergy Clin Immunol 2010; 125: 1137-45.
32. Iida M, Matsumoto K, Tomita H, Nakajima T, Akasawa A, Ohtani NY, et al. Selective down-regulation of high-affinity IgE receptor (FcεRI) α-chain messenger RNA among transcriptome in cord blood-derived versus adult peripheral blood-derived cultured human mast cells. Blood 2001; 97: 1016-22.
33. Kawata N, Takata M, Suwaki T, Tanimoto Y, Soda R, Takahashi K, et al. Signal transduction by IgG receptors induces calcium mobilization, but not histamine release, in the human basophilic cell line KU812F. Int Arch Allergy Immunol 1996; 109: 27-34.
34. De Paulis A, Marino I, Ciccarelli A, de Crescenzo G, Concardi M, Verga L, et al. Human synovial mast cells. I. Ultrastructural in situ and in vitro immunologic characterization. Arthritis Rheum 1996; 39: 1222-33.
35. Kopicky-Burd JA, Kagey-Sobotka A, Peters SP, Dvorak AM, Lennox DW, Lichtenstein LM, et al. Characterization of human synovial mast cells. J Rheumatol 1988; 15: 1326-33.
36. He S, Gaca MD, Walls AF,. The activation of synovial mast cells: modulation of histamine release by tryptase and chymase and their inhibitors. Eur J Pharmacol 2001; 412: 223-9.
37. Kimura I, Moritani Y, Tanizaki Y,. Basophils in bronchial asthma with reference to reagin-type allergy. Clin Allergy 1973; 3: 195-202.
38. Zhao W, Kepley CL, Morel PA, Okumoto LM, Fukuoka Y, Schwartz LB,. FcγRIIa, not FcγRIIb, is constitutively and functionally expressed on skin-derived human mast cells. J Immunol 2006; 177: 694-701.
39. Blom AB, Radstake TR, Holthuysen AE, Sloetjes AW, Pesman GJ, Sweep FG, et al. Increased expression of Fcγ receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor α and matrix metalloproteinase. Arthritis Rheum 2003; 48: 1002-14.
40. Highton J, Carlisle B, Palmer DG,. Changes in the phenotype of monocytes/macrophages and expression of cytokine mRNA in peripheral blood and synovial fluid of patients with rheumatoid arthritis. Clin Exp Immunol 1995; 102: 541-6.
41. Gadd SJ, Felzmann T, Majdic O, Maurer D, Petera P, Chen WJ, et al. Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from arthritis patients. Rheumatol Int 1992; 12: 153-7.
42. Schellekens GA, Visser H, de Jong BA, van den Hoogen FH, Hazes JM, Breedveld FC, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum 2000; 43: 155-63.
43. Nishimura K, Sugiyama D, Kogata Y, Tsuji G, Nakazawa T, Kawano S, et al. Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis. Ann Intern Med 2007; 146: 797-808.
44. Verpoort KN, Jol-van der Zijde CM, Papendrecht-van der Voort EA, Ioan-Facsinay A, Drijfhout JW, van Tol MJ, et al. Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response. Arthritis Rheum 2006; 54: 3799-808.
45. Trouw LA, Haisma EM, Levarht EW, van der Woude D, Ioan-Facsinay A, Daha MR, et al. Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways. Arthritis Rheum 2009; 60: 1923-31.
46. Mathsson L, Lampa J, Mullazehi M, Ronnelid J,. Immune complexes from rheumatoid arthritis synovial fluid induce FcγRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-α by peripheral blood mononuclear cells. Arthritis Res Ther 2006; 8: R64.
47. Menkes CJ, Renoux M, Laoussadi S, Mauborgne A, Bruxelle J, Cesselin F,. Substance P levels in the synovium and synovial fluid from patients with rheumatoid arthritis and osteoarthritis. J Rheumatol 1993; 20: 714-7.
48. Moxley G, Ruddy S,. Elevated C3 anaphylatoxin levels in synovial fluids from patients with rheumatoid arthritis. Arthritis Rheum 1985; 28: 1089-95.
49. Ghannadan M, Baghestanian M, Wimazal F, Eisenmenger M, Latal D, Kargul G, et al. Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies. J Invest Dermatol 1998; 111: 689-95.