Mast cells are critically involved in serum-mediated vascular leakage in chronic urticaria beyond high-affinity IgE receptor stimulation

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 66, Issue 12, 2011, Pages 1538-1545

  Bossi, F ^a   Frossi, B ^b   Radillo, O ^c   Cugno, M ^d   Tedeschi, A ^e   Riboldi, P ^d   Asero, R ^f   Tedesco, F ^a   Pucillo, C ^b  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

^c INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^f Ambulatorio di Allergologia   (Italy)

Author keywords

Chronic urticaria; Endothelial cells; High affinity IgE receptor; Mast cells; Vascular leakage

Indexed keywords

[2 METHOXY 3 (N OCTADECYLCARBAMOYLOXY)PROPYL] (2 THIAZOLIOETHYL) PHOSPHATE; FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN E RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LORATADINE;

ADULT; AGED; ARTICLE; BLOOD DONOR; BLOOD VESSEL PERMEABILITY; CELL MEMBRANE PERMEABILITY; CHRONIC URTICARIA; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; MALE; MAST CELL; MAST CELL DEGRANULATION; PERMEABILITY; PRIORITY JOURNAL; SKIN TEST; SUPERNATANT;

ADULT; AGED; CAPILLARY PERMEABILITY; CHRONIC DISEASE; ENDOTHELIAL CELLS; FEMALE; HISTAMINE RELEASE; HUMANS; MALE; MAST CELLS; MIDDLE AGED; RECEPTORS, IGE; SERUM; URTICARIA; YOUNG ADULT;

EID: 82955233848     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2011.02704.x     Document Type: Article

References (34)

1. Kikuchi Y, Fann T, Kaplan AP. Antithy-roid antibodies in chronic urticaria and angioedema. J Allergy Clin Immunol 2003;112:218. (Pubitemid 36819836)
2. Leznoff A, Josse RG, Denburg J, Dolovich J. Association of chronic urticaria and angioedema with thyroid autoimmunity. Arch Dermatol 1983;119:636-640. (Pubitemid 13028205)
3. Kaplan AP, Greaves M. Pathogenesis of chronic urticaria. Clin Exp Allergy 2009;39:777-787.
4. Hide M, Francis DM, Grattan CE, Hakimi J, Kochan JP, Greaves MW. Autoantibodies against the high-affinity IgE receptor as a cause of histamine release in chronic urticaria. N Engl J Med 1993;328:1599-1604. (Pubitemid 23151920)
5. Niimi N, Francis DM, Kermani F, O'Donnell BF, Hide M, Kobza-Black A et al. Dermal mast cell activation by autoantibodies against the high affinity IgE receptor in chronic urticaria. J Invest Dermatol 1996;106:1001-1006. (Pubitemid 26153503)
6. Fiebiger E, Maurer D, Holub H, Reininger B, Hartmann G, Woisetschlager M et al. Serum IgG autoantibodies directed against the alpha chain of Fc epsilon RI: a selective marker and pathogenetic factor for a distinct subset of chronic urticaria patients? J Clin Invest 1995;96:2606-2612.
7. Elias J, Boss E, Kaplan AP. Studies of the cellular infiltrate of chronic idiopathic urticaria: prominence of T-lymphocytes, monocytes, and mast cells. J Allergy Clin Immunol 1986;78(5 Pt 1):914-918. (Pubitemid 17194647)
8. Hennino A, Berard F, Guillot I, Saad N, Rozieres A, Nicolas JF. Pathophysiology of urticaria. Clin Rev Allergy Immunol 2006;30:3-11. (Pubitemid 43199216)
9. Levi-Schaffer F, Pe'er J. Mast cells and angiogenesis. Clin Exp Allergy 2001;31:521-524. (Pubitemid 34204273)
10. Kuna P, Kaplan AP. Relationship of histamine-releasing factors and histamine-releasing inhibitory factors to chemokine group of cytokine. Allergy Asthma Proc 1996;17:5-11. (Pubitemid 26150692)
11. Bhattacharyya SP, Drucker I, Reshef T, Kirshenbaum AS, Metcalfe DD, Mekori YA. Activated T lymphocytes induce degranulation and cytokine production by human mast cells following cell-to-cell contact. J Leukoc Biol 1998;63:337-341. (Pubitemid 28106847)
12. Tedeschi A, Asero R, Marzano AV, Lorini M, Fanoni D, Berti E et al. Plasma levels and skin-eosinophil-expression of vascular endothelial growth factor in patients with chronic urticaria. Allergy 2009;64:1616-1622.
13. Lee KH, Kim JY, Kang DS, Choi YJ, Lee WJ, Ro JY. Increased expression of endothelial cell adhesion molecules due to mediator release from human foreskin mast cells stimulated by autoantibodies in chronic urticaria sera. J Invest Dermatol 2002;118:658-663.
14. Zuberbier T, Asero R, Bindslev-Jensen C, Walter Canonica G, Church MK, Gimenez-Arnau A et al. EAACI/GA(2)LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria. Allergy 2009;64:1417-1426.
15. Sabroe RA, Grattan CE, Francis DM, Barr RM, Kobza Black A, Greaves MW. The autologous serum skin test: a screening test for autoantibodies in chronic idiopathic urticaria. Br J Dermatol 1999;140:446-452. (Pubitemid 29182875)
16. Bossi F, Fischetti F, Pellis V, Bulla R, Ferrero E, Mollnes TE et al. Platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex. J Immunol 2004;173:6921-6927. (Pubitemid 39541080)
17. Bossi F, Fischetti F, Regoli D, Durigutto P, Frossi B, Gobeil F Jr et al. Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency. J Allergy Clin Immunol 2009;124:1303-1310.
18. Kirshenbaum AS, Akin C, Wu Y, Rottem M, Goff JP, Beaven MA et al. Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. Leuk Res 2003;27:677-682. (Pubitemid 36683255)
19. Gri G, Piconese S, Frossi B, Manfroi V, Merluzzi S, Tripodo C et al. CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction. Immunity 2008;29:771-781.
20. Asero R, Tedeschi A, Lorini M, Salimbeni R, Zanoletti T, Miadonna A. Chronic urticaria: novel clinical and serological aspects. Clin Exp Allergy 2001;31:1105-1110. (Pubitemid 32862841)
21. Fisher R. The design of experiments, 1st edn. Edinburgh: Olver and Boyd, 1935.
22. Butterfield JH, Weiler D, Dewald G, Gleich GJ. Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk Res 1988;12:345-355.
23. Nilsson G, Blom T, Kusche-Gullberg M, Kjellen L, Butterfield JH, Sundstrom C et al. Phenotypic characterization of the human mast-cell line HMC-1. Scand J Immunol 1994;39:489-498. (Pubitemid 24227772)
24. Kulka M, Sheen CH, Tancowny BP, Grammer LC, Schleimer RP. Neuropeptides activate human mast cell degranulation and chemokine production. Immunology 2008;123:398-410. (Pubitemid 351171192)
25. Zuberbier T, Asero R, Bindslev-Jensen C, Walter Canonica G, Church MK, Gimenez-Arnau AM et al. EAACI/GA(2)LEN/EDF/WAO guideline: management of urticaria. Allergy 2009;64:1427-1443.
26. Grattan CE, Sabroe RA, Greaves MW. Chronic urticaria. J Am Acad Dermatol 2002;46:645-657; quiz 657-60.
27. Haas N, Toppe E, Henz BM. Microscopic morphology of different types of urticaria. Arch Dermatol 1998;134:41-46. (Pubitemid 28087112)
28. Grattan CE, Boon AP, Eady RA, Winkelmann RK. The pathology of the autologous serum skin test response in chronic urticaria resembles IgE-mediated late-phase reactions. Int Arch Allergy Appl Immunol 1990;3:198-204.
29. Eckman JA, Hamilton RG, Saini SS. Independent evaluation of a commercial test for "autoimmune" urticaria in normal and chronic urticaria subjects. J Invest Dermatol 2009;129:1584-1586.
30. Frossi B, Gri G, Tripodo C, Pucillo C. Exploring a regulatory role for mast cells: 'MCregs'? Trends Immunol 2010;31:97-102.
31. Sabroe RA, Greaves MW. Chronic idiopathic urticaria with functional autoantibodies: 12 years on. Br J Dermatol 2006;154:813-819.
32. Fujii K, Konishi K, Kanno Y, Ohgou N. Acute urticaria with elevated circulating interleukin-6 is resistant to anti-histamine treatment. J Dermatol 2001;28:248-250. (Pubitemid 32577519)
33. Eymard B, Cousin F, Nicolas JF. Prevention of aspirin-induced angioedema with an association of leukotriene inhibitors and antihistamines. Ann Dermatol Venereol 2003;130(8-9 Pt 1):787-788. (Pubitemid 37271255)
34. Greaves M. Chronic urticaria. J Allergy Clin Immunol 2000;105:664-672. (Pubitemid 30226438)