The structure-function role of C-terminus in human bitter taste receptor T2R4 signaling

Biochimica et Biophysica Acta - Biomembranes

Volumn 1848, Issue 7, 2015, Pages 1502-1508

  Upadhyaya, Jasbir ^a   Singh, Nisha ^a   Bhullar, Rajinder P ^a   Chelikani, Prashen ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Bitter taste receptor (T2R); Carboxyl terminus (C terminus); Constitutively active mutant (CAM); G protein coupled receptor (GPCR); Membrane proximal basic residue (MPBR)

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LEUCINE; LYSINE; T2R4 PROTEIN; UNCLASSIFIED DRUG; TASTE RECEPTORS, TYPE 2;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; HYDROPHOBICITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; WILD TYPE; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; FLOW CYTOMETRY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; FLOW CYTOMETRY; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84927644080     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2015.03.035     Document Type: Article

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