New point mutations in surface and core genes of hepatitis B virus associated with acute on chronic liver failure identified by complete genomic sequencing

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Xu, Hangdi ^a   Zhao, Mingfei ^a   Lou, Guohua ^b   Zheng, Min ^b   Cao, Qingyi ^b   Chen, Zhi ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; BILIRUBIN; DNA; DNA FRAGMENT; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B CORE ANTIGEN; VIRUS DNA;

ACUTE LIVER FAILURE; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CHINA; CHRONIC LIVER FAILURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA LIBRARY; FEMALE; GENE MUTATION; GENE SEQUENCE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HIGH THROUGHPUT SEQUENCING; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; POINT MUTATION; RISK FACTOR; VALIDATION PROCESS; ACUTE ON CHRONIC LIVER FAILURE; CHROMOSOMAL MAPPING; GENETICS; GENOMICS; PROCEDURES; PROMOTER REGION; VIROLOGY;

HEPATITIS B VIRUS;

ACUTE-ON-CHRONIC LIVER FAILURE; ADULT; CHROMOSOME MAPPING; DNA, VIRAL; FEMALE; GENOMICS; GENOTYPE; HEPATITIS B; HEPATITIS B CORE ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; POINT MUTATION; PROMOTER REGIONS, GENETIC;

EID: 84927622451     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123139     Document Type: Article

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