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Volumn 20, Issue 4, 2015, Pages 411-432

Platinum-induced neurotoxicity and preventive strategies: Past, present, and future

Author keywords

Models; Neurotoxicity; Pathogenesis; Platinum; Polymorphism; Prevention

Indexed keywords

AMIFOSTINE; ANTIOXIDANT; CARBOPLATIN; CHELATING AGENT; CISPLATIN; ELECTROLYTE; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; OXALIPLATIN; PLATINUM; RETINOIC ACID; SODIUM THIOSULFATE; VOLTAGE GATED SODIUM CHANNEL; ANTINEOPLASTIC AGENT; PLATINUM DERIVATIVE;

EID: 84927610343     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2014-0044     Document Type: Article
Times cited : (203)

References (206)
  • 2
    • 67349245745 scopus 로고    scopus 로고
    • Designing platinum compounds in cancer: Structures and mechanisms
    • Boulikas T, Pantos A, Bellis E et al. Designing platinum compounds in cancer: Structures and mechanisms. Cancer Ther 2007; 5: 537-583.
    • (2007) Cancer Ther , vol.5 , pp. 537-583
    • Boulikas, T.1    Pantos, A.2    Bellis, E.3
  • 3
    • 84874227759 scopus 로고    scopus 로고
    • Maleimidefunctionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery
    • Pichler V, Mayr J, Heffeter P et al. Maleimidefunctionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery. Chem Commun (Camb) 2013; 49: 2249-2251.
    • (2013) Chem Commun (Camb) , vol.49 , pp. 2249-2251
    • Pichler, V.1    Mayr, J.2    Heffeter, P.3
  • 4
    • 84873302114 scopus 로고    scopus 로고
    • Platinum compounds: A hope for future cancer chemotherapy
    • Ali I, Wani WA, Saleem K et al. Platinum compounds: A hope for future cancer chemotherapy. Anticancer Agents Med Chem 2013; 13: 296-306.
    • (2013) Anticancer Agents Med Chem , vol.13 , pp. 296-306
    • Ali, I.1    Wani, W.A.2    Saleem, K.3
  • 5
    • 84858799716 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neurotoxicity (CIPN): An update
    • Argyriou AA, Bruna J, Marmiroli P et al. Chemotherapy-induced peripheral neurotoxicity (CIPN): An update. Crit Rev Oncol Hematol 2012; 82: 51-77.
    • (2012) Crit Rev Oncol Hematol , vol.82 , pp. 51-77
    • Argyriou, A.A.1    Bruna, J.2    Marmiroli, P.3
  • 6
    • 84925357246 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neurotoxicity (CIPN): What we need and what we know
    • Cavaletti G. Chemotherapy-induced peripheral neurotoxicity (CIPN): What we need and what we know. J Peripher Nerv Syst 2014; 19: 66-76.
    • (2014) J Peripher Nerv Syst , vol.19 , pp. 66-76
    • Cavaletti, G.1
  • 7
    • 0025169939 scopus 로고
    • Cisplatin neurotoxicity
    • Mollman JE. Cisplatin neurotoxicity. N Engl J Med 1990; 322: 126-127.
    • (1990) N Engl J Med , vol.322 , pp. 126-127
    • Mollman, J.E.1
  • 9
    • 39049123158 scopus 로고    scopus 로고
    • Interventions for preventing neuropathy caused by cisplatin and related compounds
    • Albers JW, Chaudhry V, Cavaletti G et al. Interventions for preventing neuropathy caused by cisplatin and related compounds. Cochrane Database Syst Rev 2014; 3: CD005228.
    • (2014) Cochrane Database Syst Rev , vol.3
    • Albers, J.W.1    Chaudhry, V.2    Cavaletti, G.3
  • 10
    • 84893422070 scopus 로고    scopus 로고
    • Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer
    • de Castria TB, da Silva EM, Gois AF et al. Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer. Cochrane Database Syst Rev 2013; 8: CD009256.
    • (2013) Cochrane Database Syst Rev , vol.8
    • de Castria, T.B.1    da Silva, E.M.2    Gois, A.F.3
  • 13
    • 0141890143 scopus 로고    scopus 로고
    • Oxaliplatin-safety profile: Neurotoxicity
    • Grothey A. Oxaliplatin-safety profile: Neurotoxicity. Semin Oncol 2003; 30(suppl 15): 5-13.
    • (2003) Semin Oncol , vol.30 , pp. 5-13
    • Grothey, A.1
  • 14
    • 6444225487 scopus 로고    scopus 로고
    • A review of oxaliplatin and its clinical use in colorectal cancer
    • Grothey A, Goldberg RM. A review of oxaliplatin and its clinical use in colorectal cancer. Expert Opin Pharmacother 2004; 5: 2159-2170.
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 2159-2170
    • Grothey, A.1    Goldberg, R.M.2
  • 15
    • 84876345168 scopus 로고    scopus 로고
    • Advanced age and liability to oxaliplatin-induced peripheral neuropathy: Post hoc analysis of a prospective study
    • Argyriou AA, Briani C, Cavaletti G et al. Advanced age and liability to oxaliplatin-induced peripheral neuropathy: Post hoc analysis of a prospective study. Eur J Neurol 2013; 20: 788-794.
    • (2013) Eur J Neurol , vol.20 , pp. 788-794
    • Argyriou, A.A.1    Briani, C.2    Cavaletti, G.3
  • 16
    • 84872091422 scopus 로고    scopus 로고
    • Clinical pattern and associations of oxaliplatin acute neurotoxicity: A prospective study in 170 patients with colorectal cancer
    • Argyriou AA, Cavaletti G, Briani C et al. Clinical pattern and associations of oxaliplatin acute neurotoxicity: A prospective study in 170 patients with colorectal cancer. Cancer 2013; 119: 438-444.
    • (2013) Cancer , vol.119 , pp. 438-444
    • Argyriou, A.A.1    Cavaletti, G.2    Briani, C.3
  • 17
    • 84869781635 scopus 로고    scopus 로고
    • Peripheral neurotoxicity of oxaliplatin in combination with 5-fluorouracil (FOLFOX) or capecitabine (XELOX): A prospective evaluation of 150 colorectal cancer patients
    • Argyriou AA, Velasco R, Briani C et al. Peripheral neurotoxicity of oxaliplatin in combination with 5-fluorouracil (FOLFOX) or capecitabine (XELOX): A prospective evaluation of 150 colorectal cancer patients. Ann Oncol 2012; 23: 3116-3122.
    • (2012) Ann Oncol , vol.23 , pp. 3116-3122
    • Argyriou, A.A.1    Velasco, R.2    Briani, C.3
  • 18
    • 70349956408 scopus 로고    scopus 로고
    • Oxaliplatininduced neurotoxicity: Changes in axonal excitability precede developmentof neuropathy
    • Park SB, Lin CS, Krishnan AV et al. Oxaliplatininduced neurotoxicity: Changes in axonal excitability precede developmentof neuropathy. Brain 2009; 132: 2712-2723.
    • (2009) Brain , vol.132 , pp. 2712-2723
    • Park, S.B.1    Lin, C.S.2    Krishnan, A.V.3
  • 19
    • 81255167970 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neurotoxicity in the era of pharmacogenomics
    • Cavaletti G, Alberti P, Marmiroli P. Chemotherapy-induced peripheral neurotoxicity in the era of pharmacogenomics. Lancet Oncol 2011; 12: 1151-1161.
    • (2011) Lancet Oncol , vol.12 , pp. 1151-1161
    • Cavaletti, G.1    Alberti, P.2    Marmiroli, P.3
  • 20
    • 84884902436 scopus 로고    scopus 로고
    • Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatininduced peripheral neurotoxicity: Results from a prospective multicenter study
    • Argyriou AA, Cavaletti G, Antonacopoulou A et al. Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatininduced peripheral neurotoxicity: Results from a prospective multicenter study. Cancer 2013; 119: 3570-3577.
    • (2013) Cancer , vol.119 , pp. 3570-3577
    • Argyriou, A.A.1    Cavaletti, G.2    Antonacopoulou, A.3
  • 21
    • 84989229062 scopus 로고    scopus 로고
    • Medical interventions for the prevention of platinum-induced hearing loss in children with cancer
    • van As JW, van den Berg H, van Dalen EC. Medical interventions for the prevention of platinum-induced hearing loss in children with cancer. Cochrane Database Syst Rev 2014; 7: CD009219.
    • (2014) Cochrane Database Syst Rev , vol.7
    • van As, J.W.1    van den Berg, H.2    van Dalen, E.C.3
  • 22
    • 0020664982 scopus 로고
    • Hearing loss in children receiving cisplatin chemotherapy
    • McHaney VA, Thibadoux G, Hayes FA et al. Hearing loss in children receiving cisplatin chemotherapy. J Pediatr 1983; 102: 314-317.
    • (1983) J Pediatr , vol.102 , pp. 314-317
    • McHaney, V.A.1    Thibadoux, G.2    Hayes, F.A.3
  • 23
    • 5344235479 scopus 로고    scopus 로고
    • Platinum compound-related ototoxicity in children: Long-term follow-up reveals continuous worsening of hearing loss
    • Bertolini P, Lassalle M, Mercier G et al. Platinum compound-related ototoxicity in children: Long-term follow-up reveals continuous worsening of hearing loss. J Pediatr Hematol Oncol 2004; 26: 649-655.
    • (2004) J Pediatr Hematol Oncol , vol.26 , pp. 649-655
    • Bertolini, P.1    Lassalle, M.2    Mercier, G.3
  • 24
    • 0028885057 scopus 로고
    • Comparative adverse effect profiles of platinum drugs
    • McKeage MJ. Comparative adverse effect profiles of platinum drugs. Drug Saf 1995; 13: 228-244.
    • (1995) Drug Saf , vol.13 , pp. 228-244
    • McKeage, M.J.1
  • 25
    • 72649092160 scopus 로고    scopus 로고
    • Observational study of prevalence of long-term Raynaudlike phenomena and neurological side effects in testicular cancer survivors
    • Brydøy M, Oldenburg J, Klepp O et al. Observational study of prevalence of long-term Raynaudlike phenomena and neurological side effects in testicular cancer survivors. J Natl Cancer Inst 2009; 101: 1682-1695.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1682-1695
    • Brydøy, M.1    Oldenburg, J.2    Klepp, O.3
  • 26
    • 33745278586 scopus 로고    scopus 로고
    • High accumulation of platinum-DNA adducts in strial marginal cells of the cochlea is an early event in cisplatin but not carboplatin ototoxicity
    • Thomas JP, Lautermann J, Liedert B et al. High accumulation of platinum-DNA adducts in strial marginal cells of the cochlea is an early event in cisplatin but not carboplatin ototoxicity. Mol Pharmacol 2006; 70: 23-29.
    • (2006) Mol Pharmacol , vol.70 , pp. 23-29
    • Thomas, J.P.1    Lautermann, J.2    Liedert, B.3
  • 27
    • 0041621727 scopus 로고    scopus 로고
    • Neurotoxic complications of chemotherapy in patients with cancer: Clinical signs and optimal management
    • Verstappen CC, Heimans JJ, Hoekman K et al. Neurotoxic complications of chemotherapy in patients with cancer: Clinical signs and optimal management. Drugs 2003; 63: 1549-1563.
    • (2003) Drugs , vol.63 , pp. 1549-1563
    • Verstappen, C.C.1    Heimans, J.J.2    Hoekman, K.3
  • 28
    • 77955808810 scopus 로고    scopus 로고
    • Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability
    • Hill A, Bergin P, Hanning F et al. Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability. BMC Cancer 2010; 10: 451.
    • (2010) BMC Cancer , vol.10
    • Hill, A.1    Bergin, P.2    Hanning, F.3
  • 29
    • 0036534144 scopus 로고    scopus 로고
    • Acute oxaliplatin-inducedperipheralnerve hyperexcitability
    • Wilson RH, Lehky T, Thomas RR et al. Acute oxaliplatin-inducedperipheralnerve hyperexcitability. J Clin Oncol 2002; 20: 1767-1774.
    • (2002) J Clin Oncol , vol.20 , pp. 1767-1774
    • Wilson, R.H.1    Lehky, T.2    Thomas, R.R.3
  • 30
    • 33748083678 scopus 로고    scopus 로고
    • Oxaliplatin and axonal Na1channel function in vivo
    • Krishnan AV, Goldstein D, Friedlander M et al. Oxaliplatin and axonal Na1channel function in vivo. Clin Cancer Res 2006; 12: 4481-4484.
    • (2006) Clin Cancer Res , vol.12 , pp. 4481-4484
    • Krishnan, A.V.1    Goldstein, D.2    Friedlander, M.3
  • 32
    • 84894342495 scopus 로고    scopus 로고
    • Physicianassessed and patient-reported outcome measures in chemotherapy-induced sensory peripheral neurotoxicity: Two sides of the same coin
    • Alberti P, Rossi E, Cornblath DRet al. Physicianassessed and patient-reported outcome measures in chemotherapy-induced sensory peripheral neurotoxicity: Two sides of the same coin. Ann Oncol 2014; 25: 257-264.
    • (2014) Ann Oncol , vol.25 , pp. 257-264
    • Alberti, P.1    Rossi, E.2    Cornblath, D.R.3
  • 33
    • 0027214455 scopus 로고
    • Assessing the reliability of two toxicity scales: Implications for interpreting toxicity data
    • Brundage MD, Pater JL, Zee B. Assessing the reliability of two toxicity scales: Implications for interpreting toxicity data. JNatl Cancer Inst 1993; 85: 1138-1148.
    • (1993) JNatl Cancer Inst , vol.85 , pp. 1138-1148
    • Brundage, M.D.1    Pater, J.L.2    Zee, B.3
  • 34
    • 12144291025 scopus 로고    scopus 로고
    • Lackof neuroprotection by an ACTH (4-9) analogue. A randomized trial in patients treated with vincristine for Hodgkin's or non-Hodgkin's lymphoma
    • Koeppen S, VerstappenCC, KörteRet al. Lackof neuroprotection by an ACTH (4-9) analogue. A randomized trial in patients treated with vincristine for Hodgkin's or non-Hodgkin's lymphoma. J Cancer Res Clin Oncol 2004; 130: 153-160.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 153-160
    • Koeppen, S.1    Verstappen, C.C.2    Körte, R.3
  • 35
    • 0031823939 scopus 로고    scopus 로고
    • Pitfalls in grading severity of chemotherapy-induced peripheral neuropathy
    • Postma TJ, Heimans JJ, Muller MJ et al. Pitfalls in grading severity of chemotherapy-induced peripheral neuropathy. Ann Oncol 1998; 9: 739-744.
    • (1998) Ann Oncol , vol.9 , pp. 739-744
    • Postma, T.J.1    Heimans, J.J.2    Muller, M.J.3
  • 36
    • 84867333922 scopus 로고    scopus 로고
    • Discrepancy between the NCI-CTCAE and DEB-NTC scales in the evaluation of oxaliplatin-related neurotoxicity in patients with metastatic colorectal cancer
    • Inoue N, Ishida H, Sano M et al. Discrepancy between the NCI-CTCAE and DEB-NTC scales in the evaluation of oxaliplatin-related neurotoxicity in patients with metastatic colorectal cancer. Int J Clin Oncol 2012; 17: 341-347.
    • (2012) Int J Clin Oncol , vol.17 , pp. 341-347
    • Inoue, N.1    Ishida, H.2    Sano, M.3
  • 37
    • 84879697635 scopus 로고    scopus 로고
    • Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2
    • Sprowl JA, Ciarimboli G, Lancaster CS et al. Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2. Proc Natl Acad Sci USA 2013; 110: 11199-11204.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 11199-11204
    • Sprowl, J.A.1    Ciarimboli, G.2    Lancaster, C.S.3
  • 38
    • 79960525836 scopus 로고    scopus 로고
    • Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons
    • Jong NN, Nakanishi T, Liu JJ et al. Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons. J Pharmacol Exp Ther 2011; 338: 537-547.
    • (2011) J Pharmacol Exp Ther , vol.338 , pp. 537-547
    • Jong, N.N.1    Nakanishi, T.2    Liu, J.J.3
  • 39
    • 84878421473 scopus 로고    scopus 로고
    • Evaluation ofeffects of copper histidine on copper transporter 1-mediated accumulation of platinum and oxaliplatin-induced neurotoxicity in vitro and in vivo
    • IpV, Liu JJ, McKeageMJ. Evaluation ofeffects of copper histidine on copper transporter 1-mediated accumulation of platinum and oxaliplatin-induced neurotoxicity in vitro and in vivo. Clin Exp Pharmacol Physiol 2013; 40: 371-378.
    • (2013) Clin Exp Pharmacol Physiol , vol.40 , pp. 371-378
    • Ip, V.1    Liu, J.J.2    McKeage, M.J.3
  • 40
    • 84872008340 scopus 로고    scopus 로고
    • Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons
    • Liu JJ, KimY, YanF et al. Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons. Biochem Pharmacol 2013; 85: 207-215.
    • (2013) Biochem Pharmacol , vol.85 , pp. 207-215
    • Liu, J.J.1    Kim, Y.2    Yan, F.3
  • 41
    • 0037195066 scopus 로고    scopus 로고
    • Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
    • Ishida S, Lee J, Thiele DJ et al. Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci USA 2002; 99: 14298-14302.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14298-14302
    • Ishida, S.1    Lee, J.2    Thiele, D.J.3
  • 42
    • 33644767850 scopus 로고    scopus 로고
    • Role of copper transporters in the uptake and efflux of platinum containing drugs
    • Safaei R. Role of copper transporters in the uptake and efflux of platinum containing drugs. Cancer Lett 2006; 234: 34-39.
    • (2006) Cancer Lett , vol.234 , pp. 34-39
    • Safaei, R.1
  • 43
    • 30444454344 scopus 로고    scopus 로고
    • MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma
    • Guminski AD, Balleine RL, Chiew YE et al. MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma. Gynecol Oncol 2006; 100: 239-246.
    • (2006) Gynecol Oncol , vol.100 , pp. 239-246
    • Guminski, A.D.1    Balleine, R.L.2    Chiew, Y.E.3
  • 44
    • 77956476273 scopus 로고    scopus 로고
    • Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue
    • Ip V, Liu JJ, Mercer JF et al. Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue. Mol Pain 2010; 6: 53.
    • (2010) Mol Pain , vol.6
    • Ip, V.1    Liu, J.J.2    Mercer, J.F.3
  • 45
    • 79951682344 scopus 로고    scopus 로고
    • Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma
    • Yamasaki M, Makino T, Masuzawa T et al. Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma. Br J Cancer 2011; 104: 707-713.
    • (2011) Br J Cancer , vol.104 , pp. 707-713
    • Yamasaki, M.1    Makino, T.2    Masuzawa, T.3
  • 46
    • 84961977861 scopus 로고    scopus 로고
    • Hydrolysis process of the second generation platinum-based anticancer drug cis-amminedichlorocyclohexylamineplatinum(II)
    • Zhu C, Raber J, Eriksson LA. Hydrolysis process of the second generation platinum-based anticancer drug cis-amminedichlorocyclohexylamineplatinum(II). J Phys Chem B 2005; 109: 12195-12205.
    • (2005) J Phys Chem B , vol.109 , pp. 12195-12205
    • Zhu, C.1    Raber, J.2    Eriksson, L.A.3
  • 47
    • 34247614959 scopus 로고    scopus 로고
    • Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin
    • Chválová K, Brabec V, Kaspárková J. Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin. Nucleic Acids Res 2007; 35: 1812-1821.
    • (2007) Nucleic Acids Res , vol.35 , pp. 1812-1821
    • Chválová, K.1    Brabec, V.2    Kaspárková, J.3
  • 48
    • 15944426735 scopus 로고    scopus 로고
    • Cisplatin preferentially binds to DNA in dorsal root ganglion neurons in vitro and in vivo: A potential mechanism for neurotoxicity
    • McDonald ES, Randon KR, Knight A et al. Cisplatin preferentially binds to DNA in dorsal root ganglion neurons in vitro and in vivo: A potential mechanism for neurotoxicity. Neurobiol Dis 2005; 18: 305-313.
    • (2005) Neurobiol Dis , vol.18 , pp. 305-313
    • McDonald, E.S.1    Randon, K.R.2    Knight, A.3
  • 49
    • 34548455064 scopus 로고    scopus 로고
    • Repair capacity for platinum-DNA adducts determines the severity of cisplatin-induced peripheral neuropathy
    • Dzagnidze A, Katsarava Z, Makhalova J et al. Repair capacity for platinum-DNA adducts determines the severity of cisplatin-induced peripheral neuropathy. J Neurosci 2007; 27: 9451-9457.
    • (2007) J Neurosci , vol.27 , pp. 9451-9457
    • Dzagnidze, A.1    Katsarava, Z.2    Makhalova, J.3
  • 50
    • 33751534848 scopus 로고    scopus 로고
    • Neurotoxicity of oxaliplatin and cisplatin for dorsal root ganglion neurons correlates with platinum-DNA binding
    • Ta LE, Espeset L, Podratz J et al. Neurotoxicity of oxaliplatin and cisplatin for dorsal root ganglion neurons correlates with platinum-DNA binding. Neurotoxicology 2006; 27: 992-1002.
    • (2006) Neurotoxicology , vol.27 , pp. 992-1002
    • Ta, L.E.1    Espeset, L.2    Podratz, J.3
  • 51
    • 0026659298 scopus 로고
    • Cisplatin neurotoxicity: The relationship between dosage, time, and platinum concentration in neurologic tissues, and morphologic evidence of toxicity
    • Gregg RW, Molepo JM, Monpetit VJ et al. Cisplatin neurotoxicity: The relationship between dosage, time, and platinum concentration in neurologic tissues, and morphologic evidence of toxicity. J Clin Oncol 1992; 10: 795-803.
    • (1992) J Clin Oncol , vol.10 , pp. 795-803
    • Gregg, R.W.1    Molepo, J.M.2    Monpetit, V.J.3
  • 52
    • 0035914257 scopus 로고    scopus 로고
    • Nucleolar damage correlates with neurotoxicity induced by different platinum drugs
    • McKeage MJ, Hsu T, Screnci D et al. Nucleolar damage correlates with neurotoxicity induced by different platinum drugs. Br J Cancer 2001; 85: 1219-1225.
    • (2001) Br J Cancer , vol.85 , pp. 1219-1225
    • McKeage, M.J.1    Hsu, T.2    Screnci, D.3
  • 53
    • 0034041021 scopus 로고    scopus 로고
    • Toxicity of cisplatin to the central nervous system of male rabbits
    • Namikawa K, Asakura M, Minami T et al. Toxicity of cisplatin to the central nervous system of male rabbits. Biol Trace Elem Res 2000; 74: 223-235.
    • (2000) Biol Trace Elem Res , vol.74 , pp. 223-235
    • Namikawa, K.1    Asakura, M.2    Minami, T.3
  • 54
    • 0027473982 scopus 로고
    • Direct delivery of platinum-based antineoplastics to the central nervous system: A toxicity and ultrastructural study
    • Olivi A, Gilbert M, Duncan KL et al. Direct delivery of platinum-based antineoplastics to the central nervous system: A toxicity and ultrastructural study. Cancer Chemother Pharmacol 1993; 31: 449-454.
    • (1993) Cancer Chemother Pharmacol , vol.31 , pp. 449-454
    • Olivi, A.1    Gilbert, M.2    Duncan, K.L.3
  • 55
    • 0034613403 scopus 로고    scopus 로고
    • The chemotherapeutic oxaliplatin alters voltagegated Na1 channel kinetics on rat sensory neurons
    • Adelsberger H, Quasthoff S, Grosskreutz J et al. The chemotherapeutic oxaliplatin alters voltagegated Na1 channel kinetics on rat sensory neurons. Eur J Pharmacol 2000; 406: 25-32.
    • (2000) Eur J Pharmacol , vol.406 , pp. 25-32
    • Adelsberger, H.1    Quasthoff, S.2    Grosskreutz, J.3
  • 56
    • 0035745674 scopus 로고    scopus 로고
    • Electrophysiological analysis of the neurotoxic action of a funnel-web spider toxin, deltaatracotoxin-HV1a, on insect voltage-gated Na1 channels
    • Grolleau F, Stankiewicz M, Birinyi-Strachan L et al. Electrophysiological analysis of the neurotoxic action of a funnel-web spider toxin, deltaatracotoxin-HV1a, on insect voltage-gated Na1 channels. J Exp Biol 2001; 204: 711-721.
    • (2001) J Exp Biol , vol.204 , pp. 711-721
    • Grolleau, F.1    Stankiewicz, M.2    Birinyi-Strachan, L.3
  • 57
    • 84860138977 scopus 로고    scopus 로고
    • Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype NaV1. 6-resurgent and persistent current
    • Sittl R, Lampert A, Huth T et al. Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype NaV1. 6-resurgent and persistent current. Proc Natl Acad Sci USA 2012; 109: 6704-6709.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 6704-6709
    • Sittl, R.1    Lampert, A.2    Huth, T.3
  • 58
    • 84861343793 scopus 로고    scopus 로고
    • The spectral changes in EMG during a second bout eccentric contraction could be due to adaptation in muscle fibres themselves: Asimulation study
    • Dimitrov VG, Arabadzhiev TI, Dimitrova NA et al. The spectral changes in EMG during a second bout eccentric contraction could be due to adaptation in muscle fibres themselves: Asimulation study. Eur J Appl Physiol 2012; 112: 1399-1409.
    • (2012) Eur J Appl Physiol , vol.112 , pp. 1399-1409
    • Dimitrov, V.G.1    Arabadzhiev, T.I.2    Dimitrova, N.A.3
  • 59
    • 56249121217 scopus 로고    scopus 로고
    • The effects of oxaliplatin, an anticancer drug, on potassium channels of the peripheralmyelinated nerve fibres of the adult rat
    • Kagiava A, Tsingotjidou A, Emmanouilides C et al. The effects of oxaliplatin, an anticancer drug, on potassium channels of the peripheralmyelinated nerve fibres of the adult rat. Neurotoxicology 2008; 29: 1100-1106.
    • (2008) Neurotoxicology , vol.29 , pp. 1100-1106
    • Kagiava, A.1    Tsingotjidou, A.2    Emmanouilides, C.3
  • 60
    • 0033752250 scopus 로고    scopus 로고
    • Strengthduration properties and their voltage dependence as measures of a threshold conductance at the node of Ranvier of single motor axons
    • Mogyoros I, Lin CS, Kuwabara S et al. Strengthduration properties and their voltage dependence as measures of a threshold conductance at the node of Ranvier of single motor axons. Muscle Nerve 2000; 23: 1719-1726.
    • (2000) Muscle Nerve , vol.23 , pp. 1719-1726
    • Mogyoros, I.1    Lin, C.S.2    Kuwabara, S.3
  • 61
    • 0031741679 scopus 로고    scopus 로고
    • Oxaliplatin: A review of preclinical and clinical studies
    • Raymond E, Chaney SG, Taamma A et al. Oxaliplatin: A review of preclinical and clinical studies. Ann Oncol 1998; 9: 1053-1071.
    • (1998) Ann Oncol , vol.9 , pp. 1053-1071
    • Raymond, E.1    Chaney, S.G.2    Taamma, A.3
  • 62
    • 79151482213 scopus 로고    scopus 로고
    • Cisplatin induced mitochondrial DNA damage in dorsal root ganglion neurons
    • Podratz JL, Knight AM, Ta LE et al. Cisplatin induced mitochondrial DNA damage in dorsal root ganglion neurons. Neurobiol Dis 2011; 41: 661-668.
    • (2011) Neurobiol Dis , vol.41 , pp. 661-668
    • Podratz, J.L.1    Knight, A.M.2    Ta, L.E.3
  • 63
    • 20044368468 scopus 로고    scopus 로고
    • Polymorphisms in ERCC1 and grade 3 or 4 toxicity in nonsmall cell lung cancer patients
    • Suk R, Gurubhagavatula S, Park S et al. Polymorphisms in ERCC1 and grade 3 or 4 toxicity in nonsmall cell lung cancer patients. Clin Cancer Res2005; 11: 1534-1538.
    • (2005) Clin Cancer Res , vol.11 , pp. 1534-1538
    • Suk, R.1    Gurubhagavatula, S.2    Park, S.3
  • 64
    • 84897844947 scopus 로고    scopus 로고
    • Chemotherapy-induced peripheral neuropathy in adults: A comprehensive update of the literature
    • Argyriou AA, Kyritsis AP, Makatsoris T et al. Chemotherapy-induced peripheral neuropathy in adults: A comprehensive update of the literature. Cancer Manag Res 2014; 6: 135-147.
    • (2014) Cancer Manag Res , vol.6 , pp. 135-147
    • Argyriou, A.A.1    Kyritsis, A.P.2    Makatsoris, T.3
  • 65
    • 79959738646 scopus 로고    scopus 로고
    • Retrospective study of the impact of pharmacogenetic variants on paclitaxel toxicity and survival in patients with ovarian cancer
    • Bergmann TK, Gréen H, Brasch-Andersen C et al. Retrospective study of the impact of pharmacogenetic variants on paclitaxel toxicity and survival in patients with ovarian cancer. Eur J Clin Pharmacol 2011; 67: 693-700.
    • (2011) Eur J Clin Pharmacol , vol.67 , pp. 693-700
    • Bergmann, T.K.1    Gréen, H.2    Brasch-Andersen, C.3
  • 66
    • 58449133201 scopus 로고    scopus 로고
    • Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer
    • Gréen H, Söderkvist P, Rosenberg P et al. Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer. Basic Clin Pharmacol Toxicol 2009; 104: 130-137.
    • (2009) Basic Clin Pharmacol Toxicol , vol.104 , pp. 130-137
    • Gréen, H.1    Söderkvist, P.2    Rosenberg, P.3
  • 67
    • 35648997048 scopus 로고    scopus 로고
    • Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: The Scottish Randomised Trial in Ovarian Cancer
    • Marsh S, Paul J, King CR et al. Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: The Scottish Randomised Trial in Ovarian Cancer. J Clin Oncol 2007; 25: 4528-4535.
    • (2007) J Clin Oncol , vol.25 , pp. 4528-4535
    • Marsh, S.1    Paul, J.2    King, C.R.3
  • 68
    • 77954358129 scopus 로고    scopus 로고
    • Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: Results from North American Gastrointestinal IntergroupTrialN9741
    • McLeod HL, Sargent DJ, Marsh S et al. Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: Results from North American Gastrointestinal IntergroupTrialN9741. J ClinOncol2010; 28: 3227-3233.
    • (2010) J ClinOncol , vol.28 , pp. 3227-3233
    • McLeod, H.L.1    Sargent, D.J.2    Marsh, S.3
  • 69
    • 84884587739 scopus 로고    scopus 로고
    • A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen
    • Cecchin E, D'Andrea M, Lonardi S et al. A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen. Pharmacogenomics J 2013; 13: 403-409.
    • (2013) Pharmacogenomics J , vol.13 , pp. 403-409
    • Cecchin, E.1    D'Andrea, M.2    Lonardi, S.3
  • 70
    • 84893399079 scopus 로고    scopus 로고
    • Pharmacogenetic predictors of severe peripheral neuropathy in colon cancer patients treated with oxaliplatin-based adjuvant chemotherapy: A GEMCAD group study
    • Custodio A, Moreno-Rubio J, Aparicio J et al. Pharmacogenetic predictors of severe peripheral neuropathy in colon cancer patients treated with oxaliplatin-based adjuvant chemotherapy: A GEMCAD group study. Ann Oncol 2014; 25: 398-403.
    • (2014) Ann Oncol , vol.25 , pp. 398-403
    • Custodio, A.1    Moreno-Rubio, J.2    Aparicio, J.3
  • 71
    • 84861329544 scopus 로고    scopus 로고
    • Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients
    • Won HH, Lee J, Park JO et al. Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients. Cancer 2012; 118: 2828-2836.
    • (2012) Cancer , vol.118 , pp. 2828-2836
    • Won, H.H.1    Lee, J.2    Park, J.O.3
  • 72
    • 35948997380 scopus 로고    scopus 로고
    • Predictive factors ofoxaliplatin neurotoxicity: Theinvolvement of the oxalate outcome pathway
    • Gamelin L, Capitain O, Morel A et al. Predictive factors ofoxaliplatin neurotoxicity: Theinvolvement of the oxalate outcome pathway. Clin Cancer Res 2007; 13: 6359-6368.
    • (2007) Clin Cancer Res , vol.13 , pp. 6359-6368
    • Gamelin, L.1    Capitain, O.2    Morel, A.3
  • 73
    • 84878950045 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer
    • Lee KH, Chang HJ, Han SW et al. Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer. Cancer Chemother Pharmacol 2013; 71: 843-851.
    • (2013) Cancer Chemother Pharmacol , vol.71 , pp. 843-851
    • Lee, K.H.1    Chang, H.J.2    Han, S.W.3
  • 74
    • 78649301135 scopus 로고    scopus 로고
    • Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes
    • Inada M, Sato M, Morita S et al. Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes. Int J Clin Pharmacol Ther 2010; 48: 729-734.
    • (2010) Int J Clin Pharmacol Ther , vol.48 , pp. 729-734
    • Inada, M.1    Sato, M.2    Morita, S.3
  • 75
    • 63749117523 scopus 로고    scopus 로고
    • Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: A Korean populationbased study
    • Kim HS, Kim MK, Chung HH et al. Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: A Korean populationbased study. Gynecol Oncol 2009; 113: 264-269.
    • (2009) Gynecol Oncol , vol.113 , pp. 264-269
    • Kim, H.S.1    Kim, M.K.2    Chung, H.H.3
  • 76
    • 84874414652 scopus 로고    scopus 로고
    • Chemotherapy refractory testicular germ cell tumor is associated with avariant in Armadillo Repeatgenedeleted in Velco-Cardio-Facial syndrome (ARVCF)
    • Fung C, Vaughn DJ, Mitra N et al. Chemotherapy refractory testicular germ cell tumor is associated with avariant in Armadillo Repeatgenedeleted in Velco-Cardio-Facial syndrome (ARVCF). Front Endocrinol (Lausanne) 2012; 3: 163.
    • (2012) Front Endocrinol (Lausanne) , vol.3
    • Fung, C.1    Vaughn, D.J.2    Mitra, N.3
  • 77
    • 79959592515 scopus 로고    scopus 로고
    • Phase II study of biweekly S-1 and oxaliplatin combination chemotherapy inmetastatic colorectal cancer and pharmacogenetic analysis
    • Hong J, Han SW, Ham HS et al. Phase II study of biweekly S-1 and oxaliplatin combination chemotherapy inmetastatic colorectal cancer and pharmacogenetic analysis. Cancer Chemother Pharmacol 2011; 67: 1323-1331.
    • (2011) Cancer Chemother Pharmacol , vol.67 , pp. 1323-1331
    • Hong, J.1    Han, S.W.2    Ham, H.S.3
  • 78
    • 77956398850 scopus 로고    scopus 로고
    • Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05
    • Boige V, Mendiboure J, Pignon JP et al. Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05. J Clin Oncol 2010; 28: 2556-2564.
    • (2010) J Clin Oncol , vol.28 , pp. 2556-2564
    • Boige, V.1    Mendiboure, J.2    Pignon, J.P.3
  • 79
    • 57649210801 scopus 로고    scopus 로고
    • An EORTC phase I study of Bortezomib in combination with oxaliplatin, leucovorin and 5-fluorouracil in patients with advanced colorectal cancer
    • Caponigro F, Lacombe D, Twelves C et al. An EORTC phase I study of Bortezomib in combination with oxaliplatin, leucovorin and 5-fluorouracil in patients with advanced colorectal cancer. Eur J Cancer 2009; 45: 48-55.
    • (2009) Eur J Cancer , vol.45 , pp. 48-55
    • Caponigro, F.1    Lacombe, D.2    Twelves, C.3
  • 80
    • 75649126926 scopus 로고    scopus 로고
    • Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma
    • Chen YC, Tzeng CH, Chen PM et al. Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma. Cancer Sci 2010; 101: 530-535.
    • (2010) Cancer Sci , vol.101 , pp. 530-535
    • Chen, Y.C.1    Tzeng, C.H.2    Chen, P.M.3
  • 81
    • 67649971566 scopus 로고    scopus 로고
    • Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: A study of the Arbeitsgemeinschaft InternistischeOnkologie
    • Goekkurt E, Al-Batran SE, Hartmann JT et al. Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: A study of the Arbeitsgemeinschaft InternistischeOnkologie. J ClinOncol2009; 27: 2863-2873.
    • (2009) J ClinOncol , vol.27 , pp. 2863-2873
    • Goekkurt, E.1    Al-Batran, S.E.2    Hartmann, J.T.3
  • 82
    • 4444256594 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms and outcome in docetaxel-cisplatintreated advanced non-small-cell lung cancer
    • Isla D, Sarries C, RosellRet al. Single nucleotide polymorphisms and outcome in docetaxel-cisplatintreated advanced non-small-cell lung cancer. Ann Oncol 2004; 15: 1194-1203.
    • (2004) Ann Oncol , vol.15 , pp. 1194-1203
    • Isla, D.1    Sarries, C.2    Rosell, R.3
  • 83
    • 47349119840 scopus 로고    scopus 로고
    • ModifiedFOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker
    • KeamB, ImSA, HanSWet al. ModifiedFOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. BMC Cancer 2008; 8: 148.
    • (2008) BMC Cancer , vol.8
    • Keam, B.1    Im, S.A.2    Han, S.W.3
  • 84
    • 75549089797 scopus 로고    scopus 로고
    • Genetic polymorphisms and the efficacy and toxicityof cisplatin-based chemotherapy inovarian cancer patients
    • Khrunin AV, Moisseev A, Gorbunova V et al. Genetic polymorphisms and the efficacy and toxicityof cisplatin-based chemotherapy inovarian cancer patients. Pharmacogenomics J 2010; 10: 54-61.
    • (2010) Pharmacogenomics J , vol.10 , pp. 54-61
    • Khrunin, A.V.1    Moisseev, A.2    Gorbunova, V.3
  • 85
    • 34247105821 scopus 로고    scopus 로고
    • Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy
    • Ruzzo A, Graziano F, Loupakis F et al. Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy. J Clin Oncol 2007; 25: 1247-1254.
    • (2007) J Clin Oncol , vol.25 , pp. 1247-1254
    • Ruzzo, A.1    Graziano, F.2    Loupakis, F.3
  • 86
    • 68249140418 scopus 로고    scopus 로고
    • Comprehensive analysis of excision repair complementation group 1, glutathione S-transferase, thymidylate synthase and uridine diphosphate glucuronosyl transferase 1A1 polymorphisms predictive for treatment outcome in patients with advanced gastric cancer treated with FOLFOXor FOLFIRI
    • Seo BG, Kwon HC, Oh SY et al. Comprehensive analysis of excision repair complementation group 1, glutathione S-transferase, thymidylate synthase and uridine diphosphate glucuronosyl transferase 1A1 polymorphisms predictive for treatment outcome in patients with advanced gastric cancer treated with FOLFOXor FOLFIRI. Oncol Rep2009; 22: 127-136.
    • (2009) Oncol Rep , vol.22 , pp. 127-136
    • Seo, B.G.1    Kwon, H.C.2    Oh, S.Y.3
  • 87
    • 77949540995 scopus 로고    scopus 로고
    • Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): A dose-finding study and pharmacogenomic analysis
    • Zarate R, Rodríguez J, Bandres E et al. Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): A dose-finding study and pharmacogenomic analysis. Br J Cancer 2010; 102: 987-994.
    • (2010) Br J Cancer , vol.102 , pp. 987-994
    • Zarate, R.1    Rodríguez, J.2    Bandres, E.3
  • 88
    • 84880419972 scopus 로고    scopus 로고
    • Polymorphisms of GSTP1, ERCC2 and TS-39UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients
    • Kumamoto K, Ishibashi K, Okada N et al. Polymorphisms of GSTP1, ERCC2 and TS-39UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients. Oncol Lett 2013; 6: 648-654.
    • (2013) Oncol Lett , vol.6 , pp. 648-654
    • Kumamoto, K.1    Ishibashi, K.2    Okada, N.3
  • 89
    • 33744787046 scopus 로고    scopus 로고
    • Glutathione S-transferase P1 polymorphism (Ile105Val) predicts cumulative neuropathy in patients receiving oxaliplatin-based chemotherapy
    • Lecomte T, Landi B, Beaune P et al. Glutathione S-transferase P1 polymorphism (Ile105Val) predicts cumulative neuropathy in patients receiving oxaliplatin-based chemotherapy. Clin Cancer Res 2006; 12: 3050-3056.
    • (2006) Clin Cancer Res , vol.12 , pp. 3050-3056
    • Lecomte, T.1    Landi, B.2    Beaune, P.3
  • 90
    • 39549091275 scopus 로고    scopus 로고
    • Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-S-transferase-P1 and-M1, a retrospective cross sectional study
    • Oldenburg J, Kraggerud SM, Brydøy M et al. Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-S-transferase-P1 and-M1, a retrospective cross sectional study. J TranslMed 2007; 5: 70.
    • (2007) J TranslMed , vol.5
    • Oldenburg, J.1    Kraggerud, S.M.2    Brydøy, M.3
  • 91
    • 0037134707 scopus 로고    scopus 로고
    • Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
    • Stoehlmacher J, Park DJ, Zhang W et al. Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J Natl Cancer Inst 2002; 94: 936-942.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 936-942
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3
  • 92
    • 77953829803 scopus 로고    scopus 로고
    • Integrin beta-3 L33P: A new insight into the pathogenesis of chronic oxaliplatin-induced peripheral neuropathy?
    • Antonacopoulou AG, Argyriou AA, Scopa CD et al. Integrin beta-3 L33P: A new insight into the pathogenesis of chronic oxaliplatin-induced peripheral neuropathy? Eur J Neurol 2010; 17: 963-968.
    • (2010) Eur J Neurol , vol.17 , pp. 963-968
    • Antonacopoulou, A.G.1    Argyriou, A.A.2    Scopa, C.D.3
  • 93
    • 77956407511 scopus 로고    scopus 로고
    • Genetic polymorphism of GSTP1: Prediction of clinical outcome to oxaliplatin/5-FU-based chemotherapy in advanced gastric cancer
    • Li QF, Yao RY, Liu KW et al. Genetic polymorphism of GSTP1: Prediction of clinical outcome to oxaliplatin/5-FU-based chemotherapy in advanced gastric cancer. J Korean Med Sci 2010; 25: 846-852.
    • (2010) J Korean Med Sci , vol.25 , pp. 846-852
    • Li, Q.F.1    Yao, R.Y.2    Liu, K.W.3
  • 94
    • 77950299964 scopus 로고    scopus 로고
    • Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11-Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy
    • Kanai M, Yoshioka A, Tanaka S et al. Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11-Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy. Cancer Epidemiol 2010; 34: 189-193.
    • (2010) Cancer Epidemiol , vol.34 , pp. 189-193
    • Kanai, M.1    Yoshioka, A.2    Tanaka, S.3
  • 95
    • 34247882838 scopus 로고    scopus 로고
    • Glutathione-S-transferase P1 isoenzyme polymorphisms, platinum-based chemotherapy, and nonsmall cell lung cancer
    • Booton R, Ward T, Heighway J et al. Glutathione-S-transferase P1 isoenzyme polymorphisms, platinum-based chemotherapy, and nonsmall cell lung cancer. J Thorac Oncol 2006; 1: 679-683.
    • (2006) J Thorac Oncol , vol.1 , pp. 679-683
    • Booton, R.1    Ward, T.2    Heighway, J.3
  • 96
    • 60149087159 scopus 로고    scopus 로고
    • Glutathione-S-transferase pi (GSTP1) codon 105 polymorphism is not associated with oxaliplatin efficacy or toxicity in advanced colorectal cancer patients
    • Kweekel DM, Gelderblom H, Antonini NF et al. Glutathione-S-transferase pi (GSTP1) codon 105 polymorphism is not associated with oxaliplatin efficacy or toxicity in advanced colorectal cancer patients. Eur J Cancer 2009; 45: 572-578.
    • (2009) Eur J Cancer , vol.45 , pp. 572-578
    • Kweekel, D.M.1    Gelderblom, H.2    Antonini, N.F.3
  • 97
    • 53049110722 scopus 로고    scopus 로고
    • Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy
    • Par é L, Marcuello E, Alt és A et al. Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy. Br J Cancer 2008; 99: 1050-1055.
    • (2008) Br J Cancer , vol.99 , pp. 1050-1055
    • Par é, L.1    Marcuello, E.2    Alt és, A.3
  • 98
    • 69749083257 scopus 로고    scopus 로고
    • Liability of the voltage-gated sodium channel gene SCN2A R19K polymorphism to oxaliplatininduced peripheral neuropathy
    • Argyriou AA, Antonacopoulou AG, Scopa CD et al. Liability of the voltage-gated sodium channel gene SCN2A R19K polymorphism to oxaliplatininduced peripheral neuropathy. Oncology 2009; 77: 254-256.
    • (2009) Oncology , vol.77 , pp. 254-256
    • Argyriou, A.A.1    Antonacopoulou, A.G.2    Scopa, C.D.3
  • 99
    • 84934441079 scopus 로고    scopus 로고
    • Drug transporters at brain barriers: Expression and regulation by neurological disorders
    • Ashraf T, Kis O, Banerjee N et al. Drug transporters at brain barriers: Expression and regulation by neurological disorders. Adv Exp Med Biol 2012; 763: 20-69.
    • (2012) Adv Exp Med Biol , vol.763 , pp. 20-69
    • Ashraf, T.1    Kis, O.2    Banerjee, N.3
  • 100
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat Rev Cancer 2002; 2: 48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 101
    • 25444444192 scopus 로고    scopus 로고
    • CAK-cyclin-dependent activating kinase: A key kinase in cell cycle control and a target for drugs?
    • Lolli G, Johnson LN. CAK-cyclin-dependent activating kinase: A key kinase in cell cycle control and a target for drugs? Cell Cycle 2005; 4: 572-577.
    • (2005) Cell Cycle , vol.4 , pp. 572-577
    • Lolli, G.1    Johnson, L.N.2
  • 102
    • 84855897208 scopus 로고    scopus 로고
    • Temporal and spatial expression of cyclin H in rat spinal cord injury
    • Wu G, Cao J, PengCet al. Temporal and spatial expression of cyclin H in rat spinal cord injury. Neuromolecular Med 2011; 13: 187-196.
    • (2011) Neuromolecular Med , vol.13 , pp. 187-196
    • Wu, G.1    Cao, J.2    Peng, C.3
  • 103
    • 34547113112 scopus 로고    scopus 로고
    • Pharmacogenomics: Catechol O-methyltransferase to thiopurine S-methyltransferase
    • Weinshilboum RM. Pharmacogenomics: Catechol O-methyltransferase to thiopurine S-methyltransferase. Cell Mol Neurobiol 2006; 26: 539-561.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 539-561
    • Weinshilboum, R.M.1
  • 104
    • 70649113052 scopus 로고    scopus 로고
    • Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy
    • Ross CJ, Katzov-Eckert H, Dubé MP et al. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Nat Genet 2009; 41: 1345-1349.
    • (2009) Nat Genet , vol.41 , pp. 1345-1349
    • Ross, C.J.1    Katzov-Eckert, H.2    Dubé, M.P.3
  • 105
    • 84880756433 scopus 로고    scopus 로고
    • Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children
    • Pussegoda K, Ross CJ, Visscher H et al. Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children. Clin Pharmacol Ther 2013; 94: 243-251.
    • (2013) Clin Pharmacol Ther , vol.94 , pp. 243-251
    • Pussegoda, K.1    Ross, C.J.2    Visscher, H.3
  • 106
    • 84880921690 scopus 로고    scopus 로고
    • Association between GSTP1 Ile105Val polymorphism and oxaliplatin-induced neuropathy: A systematic review and meta-analysis
    • Peng Z, Wang Q, Gao J et al. Association between GSTP1 Ile105Val polymorphism and oxaliplatin-induced neuropathy: A systematic review and meta-analysis. Cancer Chemother Pharmacol 2013; 72: 305-314.
    • (2013) Cancer Chemother Pharmacol , vol.72 , pp. 305-314
    • Peng, Z.1    Wang, Q.2    Gao, J.3
  • 107
    • 17444422174 scopus 로고    scopus 로고
    • Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy
    • Kweekel DM, Gelderblom H, Guchelaar HJ. Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy. Cancer Treat Rev 2005; 31: 90-105.
    • (2005) Cancer Treat Rev , vol.31 , pp. 90-105
    • Kweekel, D.M.1    Gelderblom, H.2    Guchelaar, H.J.3
  • 108
    • 84904741649 scopus 로고    scopus 로고
    • XRCC1 and XPD genetic polymorphisms and clinical outcomes of gastric cancer patients treated with oxaliplatinbased chemotherapy: Ameta-analysis
    • Zhang X, Jiang LP, Yin Y et al. XRCC1 and XPD genetic polymorphisms and clinical outcomes of gastric cancer patients treated with oxaliplatinbased chemotherapy: Ameta-analysis. Tumour Biol 2014; 35: 5637-5645.
    • (2014) Tumour Biol , vol.35 , pp. 5637-5645
    • Zhang, X.1    Jiang, L.P.2    Yin, Y.3
  • 109
    • 72549119388 scopus 로고    scopus 로고
    • Frequency of the AGT Pro11Leu polymorphism in humans: Does diet matter?
    • Ségurel L, Lafosse S, Heyer E et al. Frequency of the AGT Pro11Leu polymorphism in humans: Does diet matter? Ann Hum Genet 2010; 74: 57-64.
    • (2010) Ann Hum Genet , vol.74 , pp. 57-64
    • Ségurel, L.1    Lafosse, S.2    Heyer, E.3
  • 110
    • 34548623314 scopus 로고    scopus 로고
    • Emerging role of mitogen-activated protein kinases in peripheral neuropathies
    • Cavaletti G, Miloso M, Nicolini G et al. Emerging role of mitogen-activated protein kinases in peripheral neuropathies. J Peripher Nerv Syst 2007; 12: 175-194.
    • (2007) J Peripher Nerv Syst , vol.12 , pp. 175-194
    • Cavaletti, G.1    Miloso, M.2    Nicolini, G.3
  • 111
    • 33947703740 scopus 로고    scopus 로고
    • Cisplatin-induced peripheral neuropathy: Neuroprotection by erythropoietin without affecting tumour growth
    • Bianchi R, Gilardini A, Rodriguez-Menendez V et al. Cisplatin-induced peripheral neuropathy: Neuroprotection by erythropoietin without affecting tumour growth. Eur J Cancer 2007; 43: 710-717.
    • (2007) Eur J Cancer , vol.43 , pp. 710-717
    • Bianchi, R.1    Gilardini, A.2    Rodriguez-Menendez, V.3
  • 112
    • 33847293709 scopus 로고    scopus 로고
    • Bortezomib-induced peripheral neurotoxicity: A neurophysiological and pathological study in the rat
    • Cavaletti G, Gilardini A, Canta A et al. Bortezomib-induced peripheral neurotoxicity: A neurophysiological and pathological study in the rat. Exp Neurol 2007; 204: 317-325.
    • (2007) Exp Neurol , vol.204 , pp. 317-325
    • Cavaletti, G.1    Gilardini, A.2    Canta, A.3
  • 113
    • 77949912801 scopus 로고    scopus 로고
    • Bortezomib-induced painful neuropathy in rats: A behavioral, neurophysiological and pathological study in rats
    • Meregalli C, Canta A, Carozzi VA et al. Bortezomib-induced painful neuropathy in rats: A behavioral, neurophysiological and pathological study in rats. Eur J Pain 2010; 14: 343-350.
    • (2010) Eur J Pain , vol.14 , pp. 343-350
    • Meregalli, C.1    Canta, A.2    Carozzi, V.A.3
  • 114
    • 0024272526 scopus 로고
    • Snail neurons as a possible model for testing neurotoxic side effects of antitumor agents: Paracrystal formation by Vinca alkaloids
    • Müller LJ, Moorer-van Delft CM, Roubos EW. Snail neurons as a possible model for testing neurotoxic side effects of antitumor agents: Paracrystal formation by Vinca alkaloids. Cancer Res 1988; 48: 7184-7188.
    • (1988) Cancer Res , vol.48 , pp. 7184-7188
    • Müller, L.J.1    Moorer-Van Delft, C.M.2    Roubos, E.W.3
  • 115
    • 0026602674 scopus 로고
    • Quantitative ultrastructural effects of cisplatin (Platinol), carboplatin (JM8), and iproplatin (JM9) on neurons of freshwater snail Lymnaea stagnalis
    • Müller LJ, Moorer-van Delft CM, Roubos EW et al. Quantitative ultrastructural effects of cisplatin (Platinol), carboplatin (JM8), and iproplatin (JM9) on neurons of freshwater snail Lymnaea stagnalis. Cancer Res 1992; 52: 963-973.
    • (1992) Cancer Res , vol.52 , pp. 963-973
    • Müller, L.J.1    Moorer-Van Delft, C.M.2    Roubos, E.W.3
  • 116
    • 0025341864 scopus 로고
    • Use of snail neurons in developing quantitative ultrastructural parameters for neurotoxic side effects of Vinca antitumor agents
    • Müller LJ, Moorer-van Delft CM, Zijl R et al. Use of snail neurons in developing quantitative ultrastructural parameters for neurotoxic side effects of Vinca antitumor agents. Cancer Res 1990; 50: 1924-1928.
    • (1990) Cancer Res , vol.50 , pp. 1924-1928
    • Müller, L.J.1    Moorer-Van Delft, C.M.2    Zijl, R.3
  • 117
    • 0033057235 scopus 로고    scopus 로고
    • Neurologic protection by amifostine
    • DiPaola RS, Schuchter L. Neurologic protection by amifostine. Semin Oncol 1999; 26(suppl 7): 82-88.
    • (1999) Semin Oncol , vol.26 , pp. 82-88
    • DiPaola, R.S.1    Schuchter, L.2
  • 118
    • 0028973492 scopus 로고
    • Nerve-growth-factor-dependent neurite outgrowth assay; a research model for chemotherapy-induced neuropathy
    • Geldof AA. Nerve-growth-factor-dependent neurite outgrowth assay; a research model for chemotherapy-induced neuropathy. J Cancer Res Clin Oncol 1995; 121: 657-660.
    • (1995) J Cancer Res Clin Oncol , vol.121 , pp. 657-660
    • Geldof, A.A.1
  • 119
    • 0031951107 scopus 로고    scopus 로고
    • Vincaalkaloid neurotoxicity measured using an in vitro model
    • Geldof AA, Minneboo A, Heimans JJ. Vincaalkaloid neurotoxicity measured using an in vitro model. J Neurooncol 1998; 37: 109-113.
    • (1998) J Neurooncol , vol.37 , pp. 109-113
    • Geldof, A.A.1    Minneboo, A.2    Heimans, J.J.3
  • 120
    • 0032718579 scopus 로고    scopus 로고
    • In vitro protection from cisplatin-induced neurotoxicity by amifostine and its metaboliteWR1065
    • Verstappen CC, Geldof AA, Postma TJ et al. In vitro protection from cisplatin-induced neurotoxicity by amifostine and its metaboliteWR1065. J Neurooncol 1999; 44: 1-5.
    • (1999) J Neurooncol , vol.44 , pp. 1-5
    • Verstappen, C.C.1    Geldof, A.A.2    Postma, T.J.3
  • 121
    • 4444339938 scopus 로고    scopus 로고
    • Amifostine protects against chemotherapy-induced neurotoxicity: An in vitro investigation
    • Verstappen CC, Postma TJ, Geldof AA et al. Amifostine protects against chemotherapy-induced neurotoxicity: An in vitro investigation. Anticancer Res 2004; 24: 2337-2341.
    • (2004) Anticancer Res , vol.24 , pp. 2337-2341
    • Verstappen, C.C.1    Postma, T.J.2    Geldof, A.A.3
  • 122
    • 84897021053 scopus 로고    scopus 로고
    • Characterization of and protection from neurotoxicity induced by oxaliplatin, bortezomib and epothilone-B
    • Ceresa C, Avan A, Giovannetti E et al. Characterization of and protection from neurotoxicity induced by oxaliplatin, bortezomib and epothilone-B. Anticancer Res 2014; 34: 517-523.
    • (2014) Anticancer Res , vol.34 , pp. 517-523
    • Ceresa, C.1    Avan, A.2    Giovannetti, E.3
  • 123
    • 84905454673 scopus 로고    scopus 로고
    • Prevention and management of chemotherapyinduced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline
    • Hershman DL, Lacchetti C, Dworkin RH et al. Prevention and management of chemotherapyinduced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol 2014; 32: 1941-1967.
    • (2014) J Clin Oncol , vol.32 , pp. 1941-1967
    • Hershman, D.L.1    Lacchetti, C.2    Dworkin, R.H.3
  • 124
    • 33750591168 scopus 로고    scopus 로고
    • Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: Involvement of ERK and p38 phosphorylation
    • Lin CH, Kuo SC, Huang LJ et al. Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: Involvement of ERK and p38 phosphorylation. J Neurosci Res 2006; 84: 1485-1494.
    • (2006) J Neurosci Res , vol.84 , pp. 1485-1494
    • Lin, C.H.1    Kuo, S.C.2    Huang, L.J.3
  • 125
    • 84897559344 scopus 로고    scopus 로고
    • Oral alphalipoic acid to prevent chemotherapy-induced peripheral neuropathy: A randomized, double-blind, placebo-controlled trial
    • Guo Y, Jones D, Palmer JL et al. Oral alphalipoic acid to prevent chemotherapy-induced peripheral neuropathy: A randomized, double-blind, placebo-controlled trial. Support Care Cancer 2014; 22: 1223-1231.
    • (2014) Support Care Cancer , vol.22 , pp. 1223-1231
    • Guo, Y.1    Jones, D.2    Palmer, J.L.3
  • 126
    • 77949432030 scopus 로고    scopus 로고
    • Prophylactic effect of amifostine on oxaliplatin-related neurotoxicity in patients with digestive tract tumors
    • Lu P, Fan QX, Wang LX et al. [Prophylactic effect of amifostine on oxaliplatin-related neurotoxicity in patients with digestive tract tumors]. Ai Zheng 2008; 27: 1117-1120.
    • (2008) Ai Zheng , vol.27 , pp. 1117-1120
    • Lu, P.1    Fan, Q.X.2    Wang, L.X.3
  • 127
    • 15544368334 scopus 로고    scopus 로고
    • A randomized phase II study of paclitaxel with carboplatin 1/2 amifostine as first line treatment in advanced ovarian carcinoma
    • De Vos FY, Bos AM, Schaapveld M et al. A randomized phase II study of paclitaxel with carboplatin 1/2 amifostine as first line treatment in advanced ovarian carcinoma. Gynecol Oncol 2005; 97: 60-67.
    • (2005) Gynecol Oncol , vol.97 , pp. 60-67
    • De Vos, F.Y.1    Bos, A.M.2    Schaapveld, M.3
  • 128
    • 26244467738 scopus 로고    scopus 로고
    • Neuroprotection with amifostine in the first-line treatment of advanced ovarian cancer with carboplatin/paclitaxel-based chemotherapy: A double-blind, placebo-controlled, randomized phase II study from the Arbeitsgemeinschaft Gynäkologische Onkologoie (AGO) Ovarian Cancer Study Group
    • Hilpert F, Stähle A, Tomé O et al. Neuroprotection with amifostine in the first-line treatment of advanced ovarian cancer with carboplatin/paclitaxel-based chemotherapy: A double-blind, placebo-controlled, randomized phase II study from the Arbeitsgemeinschaft Gynäkologische Onkologoie (AGO) Ovarian Cancer Study Group. Support Care Cancer 2005; 13: 797-805.
    • (2005) Support Care Cancer , vol.13 , pp. 797-805
    • Hilpert, F.1    Stähle, A.2    Tomé, O.3
  • 129
    • 10744221906 scopus 로고    scopus 로고
    • Protective effect of amifostine against toxicity of paclitaxel and carboplatin in non-small cell lung cancer: A single center randomized study
    • Kanat O, Evrensel T, Baran I et al. Protective effect of amifostine against toxicity of paclitaxel and carboplatin in non-small cell lung cancer: A single center randomized study. Med Oncol 2003; 20: 237-245.
    • (2003) Med Oncol , vol.20 , pp. 237-245
    • Kanat, O.1    Evrensel, T.2    Baran, I.3
  • 130
    • 0038474000 scopus 로고    scopus 로고
    • Randomized double-blind trial of combined modality treatment with or without amifostine in unresectable stage III non-small-cell lung cancer
    • Leong SS, Tan EH, FongKWet al. Randomized double-blind trial of combined modality treatment with or without amifostine in unresectable stage III non-small-cell lung cancer. J Clin Oncol 2003; 21: 1767-1774.
    • (2003) J Clin Oncol , vol.21 , pp. 1767-1774
    • Leong, S.S.1    Tan, E.H.2    Fong, K.W.3
  • 131
    • 0041700142 scopus 로고    scopus 로고
    • Phase III multicenter randomized trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients
    • Lorusso D, Ferrandina G, Greggi S et al. Phase III multicenter randomized trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients. Ann Oncol 2003; 14: 1086-1093.
    • (2003) Ann Oncol , vol.14 , pp. 1086-1093
    • Lorusso, D.1    Ferrandina, G.2    Greggi, S.3
  • 132
    • 0032968674 scopus 로고    scopus 로고
    • Cisplatin, radiation, and amifostine in carcinoma of the uterine cervix
    • Gallardo D, Mohar A, Calderillo G et al. Cisplatin, radiation, and amifostine in carcinoma of the uterine cervix. Int J Gynecol Cancer 1999; 9: 225-230.
    • (1999) Int J Gynecol Cancer , vol.9 , pp. 225-230
    • Gallardo, D.1    Mohar, A.2    Calderillo, G.3
  • 133
    • 0032775070 scopus 로고    scopus 로고
    • Randomized study of a short course of weekly cisplatin with or without amifostine in advanced head and neck cancer
    • Planting AS, Catimel G, de Mulder PH et al. Randomized study of a short course of weekly cisplatin with or without amifostine in advanced head and neck cancer. Ann Oncol 1999; 10: 693-700.
    • (1999) Ann Oncol , vol.10 , pp. 693-700
    • Planting, A.S.1    Catimel, G.2    de Mulder, P.H.3
  • 134
    • 0029902007 scopus 로고    scopus 로고
    • Amifostine pretreatment for protection against cyclophosphamideinduced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer
    • Kemp G, Rose P, Lurain J et al. Amifostine pretreatment for protection against cyclophosphamideinduced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer. J Clin Oncol 1996; 14: 2101-2112.
    • (1996) J Clin Oncol , vol.14 , pp. 2101-2112
    • Kemp, G.1    Rose, P.2    Lurain, J.3
  • 135
    • 58949087471 scopus 로고    scopus 로고
    • Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced nonsmall cell lung cancer (CALGB 30303)
    • Miller AA, Wang XF, Gu L et al. Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced nonsmall cell lung cancer (CALGB 30303). J Thorac Oncol 2008; 3: 1159-1165.
    • (2008) J Thorac Oncol , vol.3 , pp. 1159-1165
    • Miller, A.A.1    Wang, X.F.2    Gu, L.3
  • 136
    • 84886214290 scopus 로고    scopus 로고
    • Phase I drug-interaction study of effects of calcium and magnesium infusions on oxaliplatin pharmacokinetics and acute neurotoxicity in colorectal cancer patients
    • Han CH, Khwaounjoo P, Kilfoyle DH et al. Phase I drug-interaction study of effects of calcium and magnesium infusions on oxaliplatin pharmacokinetics and acute neurotoxicity in colorectal cancer patients. BMC Cancer 2013; 13: 495.
    • (2013) BMC Cancer , vol.13
    • Han, C.H.1    Khwaounjoo, P.2    Kilfoyle, D.H.3
  • 137
    • 84901675767 scopus 로고    scopus 로고
    • Phase III randomized, placebo-controlled, double-blind study of intravenous calcium and magnesium to prevent oxaliplatin-induced sensory neurotoxicity (N08CB/Alliance)
    • Loprinzi CL, Qin R, Dakhil SR et al. Phase III randomized, placebo-controlled, double-blind study of intravenous calcium and magnesium to prevent oxaliplatin-induced sensory neurotoxicity (N08CB/Alliance). J Clin Oncol 2014; 32: 997-1005.
    • (2014) J Clin Oncol , vol.32 , pp. 997-1005
    • Loprinzi, C.L.1    Qin, R.2    Dakhil, S.R.3
  • 138
    • 79952087995 scopus 로고    scopus 로고
    • Intravenous calcium and magnesium for oxaliplatininduced sensory neurotoxicity in adjuvant colon cancer: NCCTG N04C7
    • Grothey A, Nikcevich DA, Sloan JA et al. Intravenous calcium and magnesium for oxaliplatininduced sensory neurotoxicity in adjuvant colon cancer: NCCTG N04C7. J Clin Oncol 2011; 29: 421-427.
    • (2011) J Clin Oncol , vol.29 , pp. 421-427
    • Grothey, A.1    Nikcevich, D.A.2    Sloan, J.A.3
  • 139
    • 79251595227 scopus 로고    scopus 로고
    • The effect of prophylactic calcium and magnesium infusions on the incidence of neurotoxicity and clinical outcome ofoxaliplatin-basedsystemic treatmentin advanced colorectal cancer patients
    • Knijn N, Tol J, Koopman M et al. The effect of prophylactic calcium and magnesium infusions on the incidence of neurotoxicity and clinical outcome ofoxaliplatin-basedsystemic treatmentin advanced colorectal cancer patients. Eur J Cancer 2011; 47: 369-374.
    • (2011) Eur J Cancer , vol.47 , pp. 369-374
    • Knijn, N.1    Tol, J.2    Koopman, M.3
  • 140
    • 77950916227 scopus 로고    scopus 로고
    • Effect of calcium and magnesium on neurotoxicity and blood platinum concentrations in patients receiving mFOLFOX6 therapy: A prospective randomized study
    • Ishibashi K, OkadaN, Miyazaki T et al. Effect of calcium and magnesium on neurotoxicity and blood platinum concentrations in patients receiving mFOLFOX6 therapy: A prospective randomized study. Int J Clin Oncol 2010; 15: 82-87.
    • (2010) Int J Clin Oncol , vol.15 , pp. 82-87
    • Ishibashi, K.1    Okada, N.2    Miyazaki, T.3
  • 141
    • 78649766509 scopus 로고    scopus 로고
    • Use of calcium and magnesium infusions in prevention of oxaliplatin induced sensory neuropathy
    • Chay WY, Tan SH, Lo YL et al. Use of calcium and magnesium infusions in prevention of oxaliplatin induced sensory neuropathy. AsiaPac J Clin Oncol 2010; 6: 270-277.
    • (2010) AsiaPac J Clin Oncol , vol.6 , pp. 270-277
    • Chay, W.Y.1    Tan, S.H.2    Lo, Y.L.3
  • 142
    • 33845890019 scopus 로고    scopus 로고
    • Carbamazepine for prevention of oxaliplatin-related neurotoxicity in patients with advanced colorectal cancer: Final results of a randomised, controlled, multicenter phase II study
    • von Delius S, Eckel F, Wagenpfeil S et al. Carbamazepine for prevention of oxaliplatin-related neurotoxicity in patients with advanced colorectal cancer: Final results of a randomised, controlled, multicenter phase II study. Invest New Drugs 2007; 25: 173-180.
    • (2007) Invest New Drugs , vol.25 , pp. 173-180
    • von Delius, S.1    Eckel, F.2    Wagenpfeil, S.3
  • 143
    • 0028893813 scopus 로고
    • Randomized placebo-controlled multicenter evaluation of diethyldithiocarbamate for chemoprotection against cisplatin-induced toxicities
    • Gandara DR, Nahhas WA, Adelson MD et al. Randomized placebo-controlled multicenter evaluation of diethyldithiocarbamate for chemoprotection against cisplatin-induced toxicities. J Clin Oncol 1995; 13: 490-496.
    • (1995) J Clin Oncol , vol.13 , pp. 490-496
    • Gandara, D.R.1    Nahhas, W.A.2    Adelson, M.D.3
  • 144
    • 34147102323 scopus 로고    scopus 로고
    • Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients
    • WangWS, Lin JK, Lin TC et al. Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients. The Oncologist 2007; 12: 312-319.
    • (2007) The Oncologist , vol.12 , pp. 312-319
    • Wang, W.S.1    Lin, J.K.2    Lin, T.C.3
  • 145
    • 84902212165 scopus 로고    scopus 로고
    • North Central Cancer Treatment Group/Alliance trial N08CA: The use of glutathione for prevention of paclitaxel/carboplatin-induced peripheral neuropathy: A phase 3 randomized, double-blind, placebocontrolled study
    • Leal AD, Qin R, Atherton PJ et al. North Central Cancer Treatment Group/Alliance trial N08CA: The use of glutathione for prevention of paclitaxel/carboplatin-induced peripheral neuropathy: A phase 3 randomized, double-blind, placebocontrolled study. Cancer 2014; 120: 1890-1897.
    • (2014) Cancer , vol.120 , pp. 1890-1897
    • Leal, A.D.1    Qin, R.2    Atherton, P.J.3
  • 146
    • 67650302483 scopus 로고    scopus 로고
    • Administration of reduced glutathione in FOLFOX4 adjuvant treatment for colorectal cancer: Effect onoxaliplatin pharmacokinetics, Pt-DNA adduct formation, and neurotoxicity
    • Milla P, Airoldi M, Weber G et al. Administration of reduced glutathione in FOLFOX4 adjuvant treatment for colorectal cancer: Effect onoxaliplatin pharmacokinetics, Pt-DNA adduct formation, and neurotoxicity. Anticancer Drugs 2009; 20: 396-402.
    • (2009) Anticancer Drugs , vol.20 , pp. 396-402
    • Milla, P.1    Airoldi, M.2    Weber, G.3
  • 147
    • 0037102328 scopus 로고    scopus 로고
    • Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: A randomized, double-blind, placebo-controlled trial
    • Cascinu S, Catalano V, Cordella L et al. Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: A randomized, double-blind, placebo-controlled trial. J Clin Oncol 2002; 20: 3478-3483.
    • (2002) J Clin Oncol , vol.20 , pp. 3478-3483
    • Cascinu, S.1    Catalano, V.2    Cordella, L.3
  • 148
    • 0034725945 scopus 로고    scopus 로고
    • Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer
    • Schmidinger M, Budinsky AC, Wenzel C et al. Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer. Wien Klin Wochenschr 2000; 112: 617-623.
    • (2000) Wien Klin Wochenschr , vol.112 , pp. 617-623
    • Schmidinger, M.1    Budinsky, A.C.2    Wenzel, C.3
  • 149
    • 0031158107 scopus 로고    scopus 로고
    • Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: Results of a double-blind, randomised trial
    • Smyth JF, Bowman A, Perren T et al. Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: Results of a double-blind, randomised trial. Ann Oncol 1997; 8: 569-573.
    • (1997) Ann Oncol , vol.8 , pp. 569-573
    • Smyth, J.F.1    Bowman, A.2    Perren, T.3
  • 150
    • 0028815902 scopus 로고
    • Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: A randomized double-blind placebocontrolled trial
    • Cascinu S, Cordella L, Del Ferro E et al. Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: A randomized double-blind placebocontrolled trial. J Clin Oncol 1995; 13: 26-32.
    • (1995) J Clin Oncol , vol.13 , pp. 26-32
    • Cascinu, S.1    Cordella, L.2    Del Ferro, E.3
  • 151
    • 0028988236 scopus 로고
    • Weekly cisplatin 1/2 glutathione in relapsed ovarian carcinoma
    • Colombo N, Bini S, Miceli D et al. Weekly cisplatin 1/2 glutathione in relapsed ovarian carcinoma. Int J Gynecol Cancer 1995; 5: 81-86.
    • (1995) Int J Gynecol Cancer , vol.5 , pp. 81-86
    • Colombo, N.1    Bini, S.2    Miceli, D.3
  • 152
    • 0027102555 scopus 로고
    • Evaluation by somatosensory evoked potentials of the neurotoxicity of cisplatin alone or in combination with glutathione
    • Bogliun G, Marzorati L, Cavaletti G et al. Evaluation by somatosensory evoked potentials of the neurotoxicity of cisplatin alone or in combination with glutathione. Ital J Neurol Sci 1992; 13: 643-647.
    • (1992) Ital J Neurol Sci , vol.13 , pp. 643-647
    • Bogliun, G.1    Marzorati, L.2    Cavaletti, G.3
  • 153
    • 84890390387 scopus 로고    scopus 로고
    • Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): A phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy
    • Kono T, Hata T, Morita S et al. Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): A phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy. Cancer Chemother Pharmacol 2013; 72: 1283-1290.
    • (2013) Cancer Chemother Pharmacol , vol.72 , pp. 1283-1290
    • Kono, T.1    Hata, T.2    Morita, S.3
  • 154
    • 80052738134 scopus 로고    scopus 로고
    • The Kampo medicine, Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen
    • Nishioka M, Shimada M, Kurita N et al. The Kampo medicine, Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen. Int J Clin Oncol 2011; 16: 322-327.
    • (2011) Int J Clin Oncol , vol.16 , pp. 322-327
    • Nishioka, M.1    Shimada, M.2    Kurita, N.3
  • 155
    • 0031594875 scopus 로고    scopus 로고
    • Clinical trials of nimodipine as a potential neuroprotector in ovarian cancer patients treated with cisplatin
    • Cassidy J, Paul J, SoukopMet al. Clinical trials of nimodipine as a potential neuroprotector in ovarian cancer patients treated with cisplatin. Cancer Chemother Pharmacol 1998; 41: 161-166.
    • (1998) Cancer Chemother Pharmacol , vol.41 , pp. 161-166
    • Cassidy, J.1    Paul, J.2    Soukop, M.3
  • 156
    • 0031282054 scopus 로고    scopus 로고
    • A randomized, multicenter, double-blind, placebocontrolled, dose-finding study of ORG 2766 in the prevention or delay of cisplatin-induced neuropathies in women with ovarian cancer
    • Roberts JA, Jenison EL, Kim K et al. A randomized, multicenter, double-blind, placebocontrolled, dose-finding study of ORG 2766 in the prevention or delay of cisplatin-induced neuropathies in women with ovarian cancer. Gynecol Oncol 1997; 67: 172-177.
    • (1997) Gynecol Oncol , vol.67 , pp. 172-177
    • Roberts, J.A.1    Jenison, E.L.2    Kim, K.3
  • 157
    • 0028303928 scopus 로고
    • The effects of an ACTH (4-9) analogue on development of cisplatin neuropathy in testicular cancer: A randomized trial
    • van Gerven JM, Hovestadt A, Moll JW et al. The effects of an ACTH (4-9) analogue on development of cisplatin neuropathy in testicular cancer: A randomized trial. J Neurol 1994; 241: 432-435.
    • (1994) J Neurol , vol.241 , pp. 432-435
    • van Gerven, J.M.1    Hovestadt, A.2    Moll, J.W.3
  • 158
    • 0026537448 scopus 로고
    • The course of neuropathy after cessation of cisplatin treatment, combined with Org 2766 or placebo
    • Hovestadt A, van der Burg ME, Verbiest HB et al. The course of neuropathy after cessation of cisplatin treatment, combined with Org 2766 or placebo. J Neurol 1992; 239: 143-146.
    • (1992) J Neurol , vol.239 , pp. 143-146
    • Hovestadt, A.1    van der Burg, M.E.2    Verbiest, H.B.3
  • 159
    • 0025134215 scopus 로고
    • Prevention of cisplatin neurotoxicity with an ACTH(4-9) analogue in patients with ovarian cancer
    • van der Hoop RG, Vecht CJ, van der Burg ME et al. Prevention of cisplatin neurotoxicity with an ACTH(4-9) analogue in patients with ovarian cancer. N Engl J Med 1990; 322: 89-94.
    • (1990) N Engl J Med , vol.322 , pp. 89-94
    • van der Hoop, R.G.1    Vecht, C.J.2    van der Burg, M.E.3
  • 160
    • 33845915641 scopus 로고    scopus 로고
    • Efficacy of oxcarbazepine for prophylaxis against cumulative oxaliplatin-induced neuropathy
    • Argyriou AA, Chroni E, Polychronopoulos P et al. Efficacy of oxcarbazepine for prophylaxis against cumulative oxaliplatin-induced neuropathy. Neurology 2006; 67: 2253-2255.
    • (2006) Neurology , vol.67 , pp. 2253-2255
    • Argyriou, A.A.1    Chroni, E.2    Polychronopoulos, P.3
  • 161
    • 14844312018 scopus 로고    scopus 로고
    • Retinoic acid increases tissue and plasma contents of nerve growth factor and prevents neuropathy in diabetic mice
    • Arrieta O, García-Navarrete R, Zúñiga S et al. Retinoic acid increases tissue and plasma contents of nerve growth factor and prevents neuropathy in diabetic mice. Eur J Clin Invest 2005; 35: 201-207.
    • (2005) Eur J Clin Invest , vol.35 , pp. 201-207
    • Arrieta, O.1    García-Navarrete, R.2    Zúñiga, S.3
  • 162
    • 20144387524 scopus 로고    scopus 로고
    • A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy
    • Davis ID, Kiers L, MacGregor L et al. A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy. Clin Cancer Res 2005; 11: 1890-1898.
    • (2005) Clin Cancer Res , vol.11 , pp. 1890-1898
    • Davis, I.D.1    Kiers, L.2    McGregor, L.3
  • 163
    • 84855177620 scopus 로고    scopus 로고
    • Efficacy of venlafaxine for the prevention and relief of oxaliplatin-induced acute neurotoxicity: Results of EFFOX, a randomized, double-blind, placebocontrolled phase III trial
    • Durand JP, Deplanque G, Montheil V et al. Efficacy of venlafaxine for the prevention and relief of oxaliplatin-induced acute neurotoxicity: Results of EFFOX, a randomized, double-blind, placebocontrolled phase III trial. Ann Oncol 2012; 23: 200-205.
    • (2012) Ann Oncol , vol.23 , pp. 200-205
    • Durand, J.P.1    Deplanque, G.2    Montheil, V.3
  • 164
    • 83255166592 scopus 로고    scopus 로고
    • The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: Results of a randomized phase III clinical trial
    • Kottschade LA, Sloan JA, MazurczakMA et al. The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: Results of a randomized phase III clinical trial. Support Care Cancer 2011; 19: 1769-1777.
    • (2011) Support Care Cancer , vol.19 , pp. 1769-1777
    • Kottschade, L.A.1    Sloan, J.A.2    Mazurczak, M.A.3
  • 165
    • 77649243226 scopus 로고    scopus 로고
    • Vitamin E neuroprotection for cisplatin neuropathy: A randomized, placebo-controlled trial
    • Pace A, Giannarelli D, Galiè E et al. Vitamin E neuroprotection for cisplatin neuropathy: A randomized, placebo-controlled trial. Neurology 2010; 74: 762-766.
    • (2010) Neurology , vol.74 , pp. 762-766
    • Pace, A.1    Giannarelli, D.2    Galiè, E.3
  • 166
    • 33845454129 scopus 로고    scopus 로고
    • A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: Final results
    • Argyriou AA, Chroni E, Koutras A et al. A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: Final results. Support Care Cancer 2006; 14: 1134-1140.
    • (2006) Support Care Cancer , vol.14 , pp. 1134-1140
    • Argyriou, A.A.1    Chroni, E.2    Koutras, A.3
  • 167
    • 0037366026 scopus 로고    scopus 로고
    • Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy
    • Pace A, Savarese A, Picardo M et al. Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. J Clin Oncol 2003; 21: 927-931.
    • (2003) J Clin Oncol , vol.21 , pp. 927-931
    • Pace, A.1    Savarese, A.2    Picardo, M.3
  • 168
    • 33750904099 scopus 로고    scopus 로고
    • Randomized double blind (DB) placebo (Plcb) controlled phase III study assessing the efficacy of xaliproden (X) in reducing the cumulative peripheral sensory neuropathy (PSN) induced by the oxaliplatin (Ox) and 5-FU/LV combination (FOLFOX4) in firstline treatment of patients (pts) with metastatic colorectal cancer (MCRC)
    • Cassidy J, Bjarnason GA, Hickish T et al. Randomized double blind (DB) placebo (Plcb) controlled phase III study assessing the efficacy of xaliproden (X) in reducing the cumulative peripheral sensory neuropathy (PSN) induced by the oxaliplatin (Ox) and 5-FU/LV combination (FOLFOX4) in firstline treatment of patients (pts) with metastatic colorectal cancer (MCRC). J Clin Oncol 2006; 24 (suppl 18): 3507a.
    • (2006) J Clin Oncol , vol.24 , pp. 3507
    • Cassidy, J.1    Bjarnason, G.A.2    Hickish, T.3
  • 169
    • 38949097507 scopus 로고    scopus 로고
    • Sodium thiosulfate administered six hours after cisplatin does not compromise antineuroblastoma activity
    • Harned TM, Kalous O, Neuwelt A et al. Sodium thiosulfate administered six hours after cisplatin does not compromise antineuroblastoma activity. Clin Cancer Res 2008; 14: 533-540.
    • (2008) Clin Cancer Res , vol.14 , pp. 533-540
    • Harned, T.M.1    Kalous, O.2    Neuwelt, A.3
  • 170
    • 0033959645 scopus 로고    scopus 로고
    • Delayed administration of sodium thiosulfate in animal models reduces platinum ototoxicity without reduction of antitumor activity
    • Muldoon LL, Pagel MA, Kroll RA et al. Delayed administration of sodium thiosulfate in animal models reduces platinum ototoxicity without reduction of antitumor activity. Clin Cancer Res 2000; 6: 309-315.
    • (2000) Clin Cancer Res , vol.6 , pp. 309-315
    • Muldoon, L.L.1    Pagel, M.A.2    Kroll, R.A.3
  • 171
    • 23944447422 scopus 로고    scopus 로고
    • Protection against cisplatin-induced toxicities by Nacetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels
    • DickeyDT, Wu YJ, Muldoon LL et al. Protection against cisplatin-induced toxicities by Nacetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels. J Pharmacol Exp Ther 2005; 314: 1052-1058.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 1052-1058
    • Dickey, D.T.1    Wu, Y.J.2    Muldoon, L.L.3
  • 172
    • 84907995711 scopus 로고    scopus 로고
    • SIOPEL 6: A multicenter open-label randomized phase III trial of the efficacy of sodium thiosulphate (STS) in reducing ototoxicity in patients receiving cisplatin (Cis) monotherapy for standard-risk hepatoblastoma (SR-HB)
    • TPS10094a
    • Maibach R, Childs M, Rajput K et al. SIOPEL 6: A multicenter open-label randomized phase III trial of the efficacy of sodium thiosulphate (STS) in reducing ototoxicity in patients receiving cisplatin (Cis) monotherapy for standard-risk hepatoblastoma (SR-HB). J Clin Oncol 2014; 32(suppl 5): TPS10094a.
    • (2014) J Clin Oncol , vol.32
    • Maibach, R.1    Childs, M.2    Rajput, K.3
  • 173
    • 84925488064 scopus 로고    scopus 로고
    • The effects of sodium thiosulfate (STS) on cisplatin-induced hearing loss: A report from the Children's Oncology Group
    • Freyer DR. The effects of sodium thiosulfate (STS) on cisplatin-induced hearing loss: A report from the Children's Oncology Group. J Clin Oncol 2014; 32(suppl 5): 10017a.
    • (2014) J Clin Oncol , vol.32 , pp. 10017
    • Freyer, D.R.1
  • 174
    • 77956603734 scopus 로고    scopus 로고
    • BNP7787-mediated modulation of paclitaxel-and cisplatininduced aberrant microtubule protein polymerization in vitro
    • Parker AR, Petluru PN, WuMet al. BNP7787-mediated modulation of paclitaxel-and cisplatininduced aberrant microtubule protein polymerization in vitro. Mol Cancer Ther 2010; 9: 2558-2567.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2558-2567
    • Parker, A.R.1    Petluru, P.N.2    Wu, M.3
  • 175
    • 17044460959 scopus 로고    scopus 로고
    • Patients treated with antitumor drugs displaying neurological deficits are characterized by a low circulating level of nerve growth factor
    • De Santis S, Pace A, Bove L et al. Patients treated with antitumor drugs displaying neurological deficits are characterized by a low circulating level of nerve growth factor. Clin Cancer Res 2000; 6: 90-95.
    • (2000) Clin Cancer Res , vol.6 , pp. 90-95
    • De Santis, S.1    Pace, A.2    Bove, L.3
  • 176
    • 0028933576 scopus 로고
    • Effect of nerve growth factor on peptide neurons in dorsal root ganglia after taxol or cisplatin treatment and in diabetic (db/db) mice
    • Schmidt Y, Unger JW, Bartke I et al. Effect of nerve growth factor on peptide neurons in dorsal root ganglia after taxol or cisplatin treatment and in diabetic (db/db) mice. Exp Neurol 1995; 132: 16-23.
    • (1995) Exp Neurol , vol.132 , pp. 16-23
    • Schmidt, Y.1    Unger, J.W.2    Bartke, I.3
  • 177
    • 78049389903 scopus 로고    scopus 로고
    • NGF protects dorsal root ganglion neurons from oxaliplatin by modulating JNK/Sapk and ERK1/2
    • Scuteri A, Galimberti A, Ravasi M et al. NGF protects dorsal root ganglion neurons from oxaliplatin by modulating JNK/Sapk and ERK1/2. Neurosci Lett 2010; 486: 141-145.
    • (2010) Neurosci Lett , vol.486 , pp. 141-145
    • Scuteri, A.1    Galimberti, A.2    Ravasi, M.3
  • 178
    • 0033363314 scopus 로고    scopus 로고
    • Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth
    • Corcoran J, Maden M. Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth. Nat Neurosci 1999; 2: 307-308.
    • (1999) Nat Neurosci , vol.2 , pp. 307-308
    • Corcoran, J.1    Maden, M.2
  • 179
    • 23644441128 scopus 로고    scopus 로고
    • Symptomatic and neurophysiological responses of paclitaxel-or cisplatin-inducedneuropathy to oral acetyl-L-carnitine
    • Bianchi G, Vitali G, Caraceni A et al. Symptomatic and neurophysiological responses of paclitaxel-or cisplatin-inducedneuropathy to oral acetyl-L-carnitine. Eur J Cancer 2005; 41: 1746-1750.
    • (2005) Eur J Cancer , vol.41 , pp. 1746-1750
    • Bianchi, G.1    Vitali, G.2    Caraceni, A.3
  • 180
    • 35348914748 scopus 로고    scopus 로고
    • Acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy: A short review
    • De Grandis D. Acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy: A short review. CNS Drugs 2007; 21 (suppl 1): 39-46.
    • (2007) CNS Drugs , vol.21 , pp. 39-46
    • De Grandis, D.1
  • 181
    • 22944485043 scopus 로고    scopus 로고
    • Acetyl-L-carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties
    • Ghirardi O, Lo Giudice P, Pisano C et al. Acetyl-L-carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties. Anticancer Res 2005; 25: 2681-2687.
    • (2005) Anticancer Res , vol.25 , pp. 2681-2687
    • Ghirardi, O.1    Lo Giudice, P.2    Pisano, C.3
  • 182
    • 0031591477 scopus 로고    scopus 로고
    • Endogenous glutamatelevels regulatenervegrowthfactor mRNA expression in the rat dentate gyrus
    • Gwag BJ, Sessler FM, Robine V et al. Endogenous glutamatelevels regulatenervegrowthfactor mRNA expression in the rat dentate gyrus. Mol Cells 1997; 7: 425-430.
    • (1997) Mol Cells , vol.7 , pp. 425-430
    • Gwag, B.J.1    Sessler, F.M.2    Robine, V.3
  • 183
    • 0028175075 scopus 로고
    • Acetyl-L-carnitine treatment increases nerve growth factor levels and choline acetyltransferase activity in the central nervous system of aged rats
    • Taglialatela G, Navarra D, Cruciani R et al. Acetyl-L-carnitine treatment increases nerve growth factor levels and choline acetyltransferase activity in the central nervous system of aged rats. Exp Gerontol 1994; 29: 55-66.
    • (1994) Exp Gerontol , vol.29 , pp. 55-66
    • Taglialatela, G.1    Navarra, D.2    Cruciani, R.3
  • 184
    • 33646385600 scopus 로고    scopus 로고
    • Protective effect of erythropoietin and its carbamylated derivative in experimental cisplatin peripheral neurotoxicity
    • Bianchi R, Brines M, Lauria G et al. Protective effect of erythropoietin and its carbamylated derivative in experimental cisplatin peripheral neurotoxicity. Clin Cancer Res 2006; 12: 2607-2612.
    • (2006) Clin Cancer Res , vol.12 , pp. 2607-2612
    • Bianchi, R.1    Brines, M.2    Lauria, G.3
  • 185
    • 3042725549 scopus 로고    scopus 로고
    • Derivatives of erythropoietin that are tissue protective but not erythropoietic
    • LeistM, Ghezzi P, GrassoGet al. Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science 2004; 305: 239-242.
    • (2004) Science , vol.305 , pp. 239-242
    • Leist, M.1    Ghezzi, P.2    Grasso, G.3
  • 186
    • 80055100625 scopus 로고    scopus 로고
    • Retinoic acid reduces chemotherapy-induced neuropathy in an animal model and patients with lung cancer
    • Arrieta Ó, Hernández-Pedro N, Fernández-González-Arag ón MC et al. Retinoic acid reduces chemotherapy-induced neuropathy in an animal model and patients with lung cancer. Neurology 2011; 77: 987-995.
    • (2011) Neurology , vol.77 , pp. 987-995
    • Arrieta, Ó.1    Hernández-Pedro, N.2    Fernández-González-Arag ón, M.C.3
  • 187
    • 84891669984 scopus 로고    scopus 로고
    • Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment
    • Ibrahimpasic K. Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. Med Arh 2013; 67: 7-9.
    • (2013) Med Arh , vol.67 , pp. 7-9
    • Ibrahimpasic, K.1
  • 188
    • 57049105115 scopus 로고    scopus 로고
    • Hypoxiainduced deactivation of NGF-mediated ERK1/2 signaling in hippocampal cells: Neuroprotection by acetyl-L-carnitine
    • Barhwal K, Hota SK, Prasad D et al. Hypoxiainduced deactivation of NGF-mediated ERK1/2 signaling in hippocampal cells: Neuroprotection by acetyl-L-carnitine. J Neurosci Res 2008; 86: 2705-2721.
    • (2008) J Neurosci Res , vol.86 , pp. 2705-2721
    • Barhwal, K.1    Hota, S.K.2    Prasad, D.3
  • 189
    • 84864495117 scopus 로고    scopus 로고
    • DMethionine protects against cisplatin-induced neurotoxicity in cortical networks
    • Gopal KV, Wu C, Shrestha B et al. DMethionine protects against cisplatin-induced neurotoxicity in cortical networks. Neurotoxicol Teratol 2012; 34: 495-504.
    • (2012) Neurotoxicol Teratol , vol.34 , pp. 495-504
    • Gopal, K.V.1    Wu, C.2    Shrestha, B.3
  • 190
    • 0028142808 scopus 로고
    • Oxcarbazepine: Preclinical anticonvulsant profile and putative mechanisms of action
    • Schmutz M, Brugger F, Gentsch C et al. Oxcarbazepine: Preclinical anticonvulsant profile and putative mechanisms of action. Epilepsia 1994; 35(suppl 5): S47-S50.
    • (1994) Epilepsia , vol.35 , pp. S47-S50
    • Schmutz, M.1    Brugger, F.2    Gentsch, C.3
  • 191
    • 67349275597 scopus 로고    scopus 로고
    • Acetyl-Lcarnitine (ALCAR) prevents hypobaric hypoxiainduced spatial memory impairment through extracellular related kinase-mediated nuclear factor erythroid 2-related factor 2 phosphorylation
    • Barhwal K, Hota SK, Jain V et al. Acetyl-Lcarnitine (ALCAR) prevents hypobaric hypoxiainduced spatial memory impairment through extracellular related kinase-mediated nuclear factor erythroid 2-related factor 2 phosphorylation. Neuroscience 2009; 161: 501-514.
    • (2009) Neuroscience , vol.161 , pp. 501-514
    • Barhwal, K.1    Hota, S.K.2    Jain, V.3
  • 192
    • 84883878724 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for the prevention of taxaneinduced neuropathyinwomenundergoingadjuvant breast cancer therapy
    • Hershman DL, Unger JM, Crew KD et al. Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for the prevention of taxaneinduced neuropathyinwomenundergoingadjuvant breast cancer therapy. J Clin Oncol 2013; 31: 2627-2633.
    • (2013) J Clin Oncol , vol.31 , pp. 2627-2633
    • Hershman, D.L.1    Unger, J.M.2    Crew, K.D.3
  • 193
    • 33645766569 scopus 로고    scopus 로고
    • Xaliproden lessens oxaliplatinmediated neuropathy
    • Susman E. Xaliproden lessens oxaliplatinmediated neuropathy. Lancet Oncol 2006; 7: 288.
    • (2006) Lancet Oncol , vol.7
    • Susman, E.1
  • 194
    • 0041881885 scopus 로고    scopus 로고
    • Effects of goshajinkigan on corneal sensitivity, superficial punctate keratopathy and tear secretion in patients with insulin-dependent diabetes mellitus
    • Nagaki Y, Hayasaka S, Hayasaka Y et al. Effects of goshajinkigan on corneal sensitivity, superficial punctate keratopathy and tear secretion in patients with insulin-dependent diabetes mellitus. AmJ Chin Med 2003; 31: 103-109.
    • (2003) AmJ Chin Med , vol.31 , pp. 103-109
    • Nagaki, Y.1    Hayasaka, S.2    Hayasaka, Y.3
  • 195
    • 70849136155 scopus 로고    scopus 로고
    • Preventive effect of goshajinkigan on peripheral neurotoxicity of FOLFOX therapy: A placebocontrolled double-blind randomized phase II study (the GONE Study)
    • Kono T, Mishima H, Shimada M et al. Preventive effect of goshajinkigan on peripheral neurotoxicity of FOLFOX therapy: A placebocontrolled double-blind randomized phase II study (the GONE Study). Jpn J Clin Oncol 2009; 39: 847-849.
    • (2009) Jpn J Clin Oncol , vol.39 , pp. 847-849
    • Kono, T.1    Mishima, H.2    Shimada, M.3
  • 196
    • 84868008289 scopus 로고    scopus 로고
    • Peripheral neuropathies from chemotherapeutics and targeted agents: Diagnosis, treatment, and prevention
    • Grisold W, Cavaletti G, Windebank AJ. Peripheral neuropathies from chemotherapeutics and targeted agents: Diagnosis, treatment, and prevention. Neuro-oncol 2012; 14(suppl 4): iv45-iv54.
    • (2012) Neuro-oncol , vol.14 , pp. iv45-iv54
    • Grisold, W.1    Cavaletti, G.2    Windebank, A.J.3
  • 197
    • 84878326836 scopus 로고    scopus 로고
    • Timing is important in medication administration: A timely review of chronotherapy research
    • Kaur G, Phillips C, Wong K et al. Timing is important in medication administration: A timely review of chronotherapy research. Int J Clin Pharmacol 2013; 35: 344-358.
    • (2013) Int J Clin Pharmacol , vol.35 , pp. 344-358
    • Kaur, G.1    Phillips, C.2    Wong, K.3
  • 198
    • 1842293964 scopus 로고    scopus 로고
    • Circadian-system alterations during cancer processes: A review
    • Mormont MC, Lévi F. Circadian-system alterations during cancer processes: A review. Int J Cancer 1997; 70: 241-247.
    • (1997) Int J Cancer , vol.70 , pp. 241-247
    • Mormont, M.C.1    Lévi, F.2
  • 199
    • 77649237487 scopus 로고    scopus 로고
    • Chronomodulated chemotherapy versus conventional chemotherapy for advanced colorectal cancer: A meta-analysis of five randomized controlled trials
    • Liao C, Li J, Bin Q et al. Chronomodulated chemotherapy versus conventional chemotherapy for advanced colorectal cancer: A meta-analysis of five randomized controlled trials. Int J Colorectal Dis 2010; 25: 343-350.
    • (2010) Int J Colorectal Dis , vol.25 , pp. 343-350
    • Liao, C.1    Li, J.2    Bin, Q.3
  • 200
    • 84855175795 scopus 로고    scopus 로고
    • Calcium and magnesium prophylaxis for oxaliplatin-related neurotoxicity: Is it a trade-off between drug efficacy and toxicity?
    • Cavaletti G. Calcium and magnesium prophylaxis for oxaliplatin-related neurotoxicity: Is it a trade-off between drug efficacy and toxicity? The Oncologist 2011; 16: 1667-1668.
    • (2011) The Oncologist , vol.16 , pp. 1667-1668
    • Cavaletti, G.1
  • 201
    • 84855181458 scopus 로고    scopus 로고
    • Calcium and magnesium prophylaxis for oxaliplatin-related neurotoxicity: Is it a trade-off between drug efficacy and toxicity?
    • Khattak MA. Calcium and magnesium prophylaxis for oxaliplatin-related neurotoxicity: Is it a trade-off between drug efficacy and toxicity? The Oncologist 2011; 16: 1780-1783.
    • (2011) The Oncologist , vol.16 , pp. 1780-1783
    • Khattak, M.A.1
  • 202
    • 84875672647 scopus 로고    scopus 로고
    • Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: A randomized clinical trial
    • Smith EM, Pang H, Cirrincione C et al. Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: A randomized clinical trial. JAMA 2013; 309: 1359-1367.
    • (2013) JAMA , vol.309 , pp. 1359-1367
    • Smith, E.M.1    Pang, H.2    Cirrincione, C.3
  • 203
    • 0036299151 scopus 로고    scopus 로고
    • Phase III evaluation of nortriptyline for alleviation of symptoms of cis-platinum-induced peripheral neuropathy
    • Hammack JE, Michalak JC, Loprinzi CL et al. Phase III evaluation of nortriptyline for alleviation of symptoms of cis-platinum-induced peripheral neuropathy. Pain 2002; 98: 195-203.
    • (2002) Pain , vol.98 , pp. 195-203
    • Hammack, J.E.1    Michalak, J.C.2    Loprinzi, C.L.3
  • 204
    • 35648929958 scopus 로고    scopus 로고
    • Efficacy of gabapentin in the management of chemotherapyinduced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3)
    • Rao RD, Michalak JC, Sloan JA et al. Efficacy of gabapentin in the management of chemotherapyinduced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3). Cancer 2007; 110: 2110-2118.
    • (2007) Cancer , vol.110 , pp. 2110-2118
    • Rao, R.D.1    Michalak, J.C.2    Sloan, J.A.3
  • 205
    • 46049110377 scopus 로고    scopus 로고
    • Efficacy of lamotrigine in the management of chemotherapyinduced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled trial, N01C3
    • Rao RD, Flynn PJ, Sloan JA et al. Efficacy of lamotrigine in the management of chemotherapyinduced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled trial, N01C3. Cancer 2008; 112: 2802-2808.
    • (2008) Cancer , vol.112 , pp. 2802-2808
    • Rao, R.D.1    Flynn, P.J.2    Sloan, J.A.3
  • 206
    • 80051670484 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA
    • Barton DL, Wos EJ, Qin R et al. A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA. Support Care Cancer 2011; 19: 833-841.
    • (2011) Support Care Cancer , vol.19 , pp. 833-841
    • Barton, D.L.1    Wos, E.J.2    Qin, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.