메뉴 건너뛰기




Volumn 14, Issue 7, 1996, Pages 2101-2112

Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: Results of a randomized control trial in patients with advanced ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

AMIFOSTINE; CISPLATIN; CYCLOPHOSPHAMIDE;

EID: 0029902007     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1996.14.7.2101     Document Type: Article
Times cited : (463)

References (83)
  • 1
    • 0001432389 scopus 로고
    • Biological characteristics of some improved radioprotectors
    • Brady LW (ed): New York, NY, Masson
    • Davidson DE, Grenan MM, Sweeney TR: Biological characteristics of some improved radioprotectors, in Brady LW (ed): Radiation Sensitizers. New York, NY, Masson, 1980; pp 309-320
    • (1980) Radiation Sensitizers , pp. 309-320
    • Davidson, D.E.1    Grenan, M.M.2    Sweeney, T.R.3
  • 2
    • 0019424730 scopus 로고
    • Differential protection against cytotoxic chemotherapeutic effects on bone marrow CPUs by WR-2721
    • Wasserman TH, Phillips TL, Ross G, et al: Differential protection against cytotoxic chemotherapeutic effects on bone marrow CPUs by WR-2721. Cancer Clin Trials 4:3-6, 1981
    • (1981) Cancer Clin Trials , vol.4 , pp. 3-6
    • Wasserman, T.H.1    Phillips, T.L.2    Ross, G.3
  • 3
    • 0020413641 scopus 로고
    • Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721
    • Valeriote F, Tolen S: Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721. Cancer Res 42:4330-4331, 1982
    • (1982) Cancer Res , vol.42 , pp. 4330-4331
    • Valeriote, F.1    Tolen, S.2
  • 4
    • 0020324128 scopus 로고
    • The modification of melphalan toxicity in tumor bearing mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (WR-2721)
    • Millar JL, McElwain TJ, Clutterbuck RD, et al: The modification of melphalan toxicity in tumor bearing mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (WR-2721). Am J Clin Oncol 5:321-328, 1982
    • (1982) Am J Clin Oncol , vol.5 , pp. 321-328
    • Millar, J.L.1    McElwain, T.J.2    Clutterbuck, R.D.3
  • 5
    • 0019304979 scopus 로고
    • The role of WR-2721 in radiotherapy and/or chemotherapy
    • Yuhas JM, Spellman JM, Culo F: The role of WR-2721 in radiotherapy and/or chemotherapy. Cancer Clin Trials 3:211-216, 1980
    • (1980) Cancer Clin Trials , vol.3 , pp. 211-216
    • Yuhas, J.M.1    Spellman, J.M.2    Culo, F.3
  • 6
    • 0028364704 scopus 로고
    • Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support
    • Shpall EJ, Stemmer SM, Hami L, et al: Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support. Blood 83:3132-3137, 1994
    • (1994) Blood , vol.83 , pp. 3132-3137
    • Shpall, E.J.1    Stemmer, S.M.2    Hami, L.3
  • 7
    • 84871469890 scopus 로고
    • WR 2721 (ethiofos) protects normal progenitor/stem cells from cyclophosphamide derivatives toxicity, with preservation of their anti-leukemic effects: Application to in vitro marrow purging
    • Guigon M (ed): ed 229. Paris, France, Colloque INSERM/John Libbey Eurotext
    • Douay L, Hu C, Giarratana MC, et al: WR 2721 (ethiofos) protects normal progenitor/stem cells from cyclophosphamide derivatives toxicity, with preservation of their anti-leukemic effects: Application to in vitro marrow purging, in Guigon M (ed): The Negative Regulation of Hematopoiesis (ed 229). Paris, France, Colloque INSERM/John Libbey Eurotext, 1993, pp 469-476
    • (1993) The Negative Regulation of Hematopoiesis , pp. 469-476
    • Douay, L.1    Hu, C.2    Giarratana, M.C.3
  • 8
    • 0018872013 scopus 로고
    • Selective inhibition of the nephrotoxicity of cis-dichlorodiammineplatinum (II) by WR-2721 without altering its antitumor properties
    • Yuhas JM, Culo F: Selective inhibition of the nephrotoxicity of cis-dichlorodiammineplatinum (II) by WR-2721 without altering its antitumor properties. Cancer Treat Rep 64:57-64, 1980
    • (1980) Cancer Treat Rep , vol.64 , pp. 57-64
    • Yuhas, J.M.1    Culo, F.2
  • 9
    • 0028323126 scopus 로고
    • Effects of the modulating agent WR-2721 on myelotoxicity and antitumour activity in carboplatin-treated mice
    • Treskes M, Boven E, Loosdrecht AA, et al: Effects of the modulating agent WR-2721 on myelotoxicity and antitumour activity in carboplatin-treated mice. Eur J Cancer 30:183-187, 1994
    • (1994) Eur J Cancer , vol.30 , pp. 183-187
    • Treskes, M.1    Boven, E.2    Loosdrecht, A.A.3
  • 10
    • 0026749823 scopus 로고
    • Time dependence of the selective modulation of cisplatin-induced nephrotoxicity by WR2721 in the mouse
    • Treskes M, Boven E, Holwerda U, et al: Time dependence of the selective modulation of cisplatin-induced nephrotoxicity by WR2721 in the mouse. Cancer Res 52:2257-2260, 1992
    • (1992) Cancer Res , vol.52 , pp. 2257-2260
    • Treskes, M.1    Boven, E.2    Holwerda, U.3
  • 11
    • 0013590441 scopus 로고
    • Protection against cis-platin neurotoxicity in cultured dorsal root ganglion cells by WR 2721
    • Clearwater, FL, February 2-5
    • Mollman JE: Protection against cis-platin neurotoxicity in cultured dorsal root ganglion cells by WR 2721. Seventh International Conference on Chemical Modifiers of Cancer Treatment. Clearwater, FL, February 2-5, 1991, pp 328-329
    • (1991) Seventh International Conference on Chemical Modifiers of Cancer Treatment , pp. 328-329
    • Mollman, J.E.1
  • 12
    • 0342820455 scopus 로고
    • WR-2721 protects neurons of the snail lymnaea stagnalis from cisplatin induced toxicity
    • abstr 3330
    • Müller LJ, Moorer-Van Delft CM, Treskes M, et al: WR-2721 protects neurons of the snail lymnaea stagnalis from cisplatin induced toxicity. Proc Am Assoc Cancer Res 33:557, 1992 (abstr 3330)
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 557
    • Müller, L.J.1    Moorer-Van Delft, C.M.2    Treskes, M.3
  • 13
    • 0024559604 scopus 로고
    • Radiation protectors: The unexpected benefits
    • Grdina DJ, Sigdestad CP: Radiation protectors: The unexpected benefits. Drug Metab Rev 20:13-42, 1989
    • (1989) Drug Metab Rev , vol.20 , pp. 13-42
    • Grdina, D.J.1    Sigdestad, C.P.2
  • 14
    • 0022551072 scopus 로고
    • Protection against cis-Diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol
    • Nagy B, Dale PJ, Grdina DJ: Protection against cis-Diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol. Cancer Res 46:1132-1135, 1986
    • (1986) Cancer Res , vol.46 , pp. 1132-1135
    • Nagy, B.1    Dale, P.J.2    Grdina, D.J.3
  • 15
    • 0022538195 scopus 로고
    • Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells
    • Nagy B, Grdina DJ: Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells. Int J Radiat Oncol Biol Phys 12:1475-1478, 1986
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1475-1478
    • Nagy, B.1    Grdina, D.J.2
  • 16
    • 0023816043 scopus 로고
    • Radioprotectors in treatment therapy to reduce risk in secondary tumor induction
    • Grdina DJ, Nagy B, Sigdestad CP: Radioprotectors in treatment therapy to reduce risk in secondary tumor induction. Pharmacol Ther 39:21-25, 1988
    • (1988) Pharmacol Ther , vol.39 , pp. 21-25
    • Grdina, D.J.1    Nagy, B.2    Sigdestad, C.P.3
  • 17
    • 0021718290 scopus 로고
    • Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
    • Milas L, Hunter NR, Stephens LC, et al: Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid. Cancer Res 44:5567-5569, 1984
    • (1984) Cancer Res , vol.44 , pp. 5567-5569
    • Milas, L.1    Hunter, N.R.2    Stephens, L.C.3
  • 19
    • 0023258489 scopus 로고
    • WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma
    • Glover DJ, Glick JH, Weiler C, et al: WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma. J Clin Oncol 5:574-578, 1987
    • (1987) J Clin Oncol , vol.5 , pp. 574-578
    • Glover, D.J.1    Glick, J.H.2    Weiler, C.3
  • 20
    • 0022655609 scopus 로고
    • WR-2721 protects against the hematologic toxicity of cyclophosphamide: A controlled phase II Trial
    • Glover DJ, Glick JH, Weiler C, et al: WR-2721 protects against the hematologic toxicity of cyclophosphamide: A controlled phase II Trial. J Clin Oncol 4:584-588, 1986
    • (1986) J Clin Oncol , vol.4 , pp. 584-588
    • Glover, D.J.1    Glick, J.H.2    Weiler, C.3
  • 21
    • 0023948344 scopus 로고
    • Cisplatin neuropathy: Risk factors, prognosis and protection by WR-2721
    • Mollman JE, Glover DJ, Hogan WM, et al: Cisplatin neuropathy: Risk factors, prognosis and protection by WR-2721. Cancer 61:2192-2195, 1988
    • (1988) Cancer , vol.61 , pp. 2192-2195
    • Mollman, J.E.1    Glover, D.J.2    Hogan, W.M.3
  • 22
    • 0025195396 scopus 로고
    • Comprehensive criteria for assessing therapy-induced toxicity
    • Ajani JA, Welch SR, Raber MN, et al: Comprehensive criteria for assessing therapy-induced toxicity. Cancer Invest 8:147-159, 1990
    • (1990) Cancer Invest , vol.8 , pp. 147-159
    • Ajani, J.A.1    Welch, S.R.2    Raber, M.N.3
  • 23
    • 0017744944 scopus 로고
    • Group sequential methods in the design and analysis of clinical trials
    • Pocock SJ: Group sequential methods in the design and analysis of clinical trials. Biometrika 64:191-199, 1977
    • (1977) Biometrika , vol.64 , pp. 191-199
    • Pocock, S.J.1
  • 24
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 16:31-41, 1976
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 25
    • 0027517297 scopus 로고
    • Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas
    • Gerhartz HH, Engelhard M, Meusers P, et al: Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas. Blood 82:2329-2339, 1993
    • (1993) Blood , vol.82 , pp. 2329-2339
    • Gerhartz, H.H.1    Engelhard, M.2    Meusers, P.3
  • 26
    • 0026000905 scopus 로고
    • Effects of recombinant human granulocyte-macrophage colony-stimulating factor on myelosuppression induced by multiple cycles of high-dose chemotherapy in patients with advanced breast cancer
    • Hoekman K, Wagstaff J, van Groeningen CJ, et al: Effects of recombinant human granulocyte-macrophage colony-stimulating factor on myelosuppression induced by multiple cycles of high-dose chemotherapy in patients with advanced breast cancer. J Natl Cancer Inst 83:1546-1553, 1991
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1546-1553
    • Hoekman, K.1    Wagstaff, J.2    Van Groeningen, C.J.3
  • 27
    • 0020062969 scopus 로고
    • Cisplatin hydration with and without mannitol diuresis in refractory disseminated malignant melanoma: A Southwest Oncology Group study
    • Al-Sarraf M, Fletcher WS, Oishi N, et al: Cisplatin hydration with and without mannitol diuresis in refractory disseminated malignant melanoma: A Southwest Oncology Group study. Cancer Treat Rep 66:31-35, 1982
    • (1982) Cancer Treat Rep , vol.66 , pp. 31-35
    • Al-Sarraf, M.1    Fletcher, W.S.2    Oishi, N.3
  • 28
    • 0018146764 scopus 로고
    • Acute renal failure after cis-dichlorodiammineplatinum(II) and gentamicin-cephalothin therapies
    • Gonzalez-Vitale JC, Hayes DM, Cvitkovic E, et al: Acute renal failure after cis-dichlorodiammineplatinum(II) and gentamicin-cephalothin therapies. Cancer Treat Rep 62:693-698, 1978
    • (1978) Cancer Treat Rep , vol.62 , pp. 693-698
    • Gonzalez-Vitale, J.C.1    Hayes, D.M.2    Cvitkovic, E.3
  • 30
    • 0023835775 scopus 로고
    • The effect of cisplatin on renal function in patients with testicular tumours
    • Macleod PM, Tyrell CJ, Keeling DH: The effect of cisplatin on renal function in patients with testicular tumours. Clin Radiol 39:190-192, 1988
    • (1988) Clin Radiol , vol.39 , pp. 190-192
    • Macleod, P.M.1    Tyrell, C.J.2    Keeling, D.H.3
  • 32
    • 0018100922 scopus 로고
    • Long-term effect of cis-diamminedichloride platinum (CDDP) on renal function and structure in man
    • Dentino M, Luft FC, Yum MN, et al: Long-term effect of cis-diamminedichloride platinum (CDDP) on renal function and structure in man. Cancer 41:1274-1281, 1978
    • (1978) Cancer , vol.41 , pp. 1274-1281
    • Dentino, M.1    Luft, F.C.2    Yum, M.N.3
  • 33
    • 0023028271 scopus 로고
    • The long-term effect of cisplatin on renal function
    • Fjeldborg P, Sorensen J, Helkjaer PE: The long-term effect of cisplatin on renal function. Cancer 58:2214-2217, 1986
    • (1986) Cancer , vol.58 , pp. 2214-2217
    • Fjeldborg, P.1    Sorensen, J.2    Helkjaer, P.E.3
  • 34
    • 0022993630 scopus 로고
    • Cumulative renal tubular damage associated with cisplatin nephrotoxicity
    • Goren MP, Wright RK, Horowitz ME: Cumulative renal tubular damage associated with cisplatin nephrotoxicity. Cancer Chemother Pharmacol 18:69-73, 1986
    • (1986) Cancer Chemother Pharmacol , vol.18 , pp. 69-73
    • Goren, M.P.1    Wright, R.K.2    Horowitz, M.E.3
  • 35
    • 0022496829 scopus 로고
    • Acute and long-term nephrotoxicity of cis-platinum in man
    • Groth S, Nielson H, Srenson JB, et al: Acute and long-term nephrotoxicity of cis-platinum in man. Cancer Chemother Pharmacol 17:191-196, 1986
    • (1986) Cancer Chemother Pharmacol , vol.17 , pp. 191-196
    • Groth, S.1    Nielson, H.2    Srenson, J.B.3
  • 36
    • 0025134906 scopus 로고
    • Renal function related to different treatment modalities for malignant germ cell tumors
    • Aass N, Fossa SD, Aas M, et al: Renal function related to different treatment modalities for malignant germ cell tumors. Br J Cancer 62:842-846, 1990
    • (1990) Br J Cancer , vol.62 , pp. 842-846
    • Aass, N.1    Fossa, S.D.2    Aas, M.3
  • 37
    • 0024440650 scopus 로고
    • Carboplatin dosage: Prospective evaluation of a simple formula based on renal function
    • Calvert AH, Newell DR, Gumbrell LA, et al: Carboplatin dosage: Prospective evaluation of a simple formula based on renal function. J Clin Oncol 7:1748-1756, 1989
    • (1989) J Clin Oncol , vol.7 , pp. 1748-1756
    • Calvert, A.H.1    Newell, D.R.2    Gumbrell, L.A.3
  • 38
    • 0022379952 scopus 로고
    • Prospective validation of a pharmacologically based dosing scheme for the cis-diamminedichloroplatinum(II) analogue diamminecyclobutanedi-carboxylatoplatinum
    • Egorin MJ, Van Echo DA, Olman EA, et al: Prospective validation of a pharmacologically based dosing scheme for the cis-diamminedichloroplatinum(II) analogue diamminecyclobutanedi-carboxylatoplatinum. Cancer Res 45:6502-6506, 1985
    • (1985) Cancer Res , vol.45 , pp. 6502-6506
    • Egorin, M.J.1    Van Echo, D.A.2    Olman, E.A.3
  • 39
    • 0025775557 scopus 로고
    • Dose-toxicity relationship of carboplatin in combination with cyclophosphamide in ovarian cancer patients
    • Sorensen BT, Stromgren A, Jakobsen P, et al: Dose-toxicity relationship of carboplatin in combination with cyclophosphamide in ovarian cancer patients. Cancer Chemother Pharmacol 28:397-401, 1991
    • (1991) Cancer Chemother Pharmacol , vol.28 , pp. 397-401
    • Sorensen, B.T.1    Stromgren, A.2    Jakobsen, P.3
  • 40
    • 0017873070 scopus 로고
    • The clinical pharmacology of methotrexate
    • Bleyer WA: The clinical pharmacology of methotrexate. Cancer 41:36-51, 1978
    • (1978) Cancer , vol.41 , pp. 36-51
    • Bleyer, W.A.1
  • 41
    • 0021170973 scopus 로고
    • Methotrexate-related deaths in patients previously treated with cis-diamminedichloride platinum
    • Haim N, Kedar A, Robinson E: Methotrexate-related deaths in patients previously treated with cis-diamminedichloride platinum. Cancer Chemother Pharmacol 13:223-225, 1984
    • (1984) Cancer Chemother Pharmacol , vol.13 , pp. 223-225
    • Haim, N.1    Kedar, A.2    Robinson, E.3
  • 42
    • 0021133555 scopus 로고
    • The effect of prior cisplatin therapy on the pharmacokinetics of high-dose methotrexate
    • Crom WR, Pratt CB, Green AA, et al: The effect of prior cisplatin therapy on the pharmacokinetics of high-dose methotrexate. J Clin Oncol 2:655-661, 1984
    • (1984) J Clin Oncol , vol.2 , pp. 655-661
    • Crom, W.R.1    Pratt, C.B.2    Green, A.A.3
  • 43
    • 0023214403 scopus 로고
    • Urinary N-acetyl-B-D-glucosaminidase and serum creatinine concentrations predict impaired excretion of methotrexate
    • Goren MP, Wright RK, Horowitz ME, et al: Urinary N-acetyl-B-D-glucosaminidase and serum creatinine concentrations predict impaired excretion of methotrexate. J Clin Oncol 5:804-810, 1987
    • (1987) J Clin Oncol , vol.5 , pp. 804-810
    • Goren, M.P.1    Wright, R.K.2    Horowitz, M.E.3
  • 44
    • 0020570349 scopus 로고
    • Cisplatin-induced changes in bleomycin elimination
    • Yee GC, Crom WR, Champion JE, et al: Cisplatin-induced changes in bleomycin elimination. Cancer Treat Rep 67:587-589, 1983
    • (1983) Cancer Treat Rep , vol.67 , pp. 587-589
    • Yee, G.C.1    Crom, W.R.2    Champion, J.E.3
  • 45
    • 0017593101 scopus 로고
    • Effects of variations in renal function on the clinical pharmacology of bleomycin administered as an IV bolus
    • Crooke ST, Comis RL, Einhorn LH, et al: Effects of variations in renal function on the clinical pharmacology of bleomycin administered as an IV bolus. Cancer Treat Rep 61:1631-1636, 1977
    • (1977) Cancer Treat Rep , vol.61 , pp. 1631-1636
    • Crooke, S.T.1    Comis, R.L.2    Einhorn, L.H.3
  • 46
    • 0021353942 scopus 로고
    • Influence of platinum-induced renal toxicity on bleomycin-induced pulmonary toxicity in patients with disseminated testicular carcinoma
    • van Barneweld PWC, Sleiffer DT, van der Mark TW, et al: Influence of platinum-induced renal toxicity on bleomycin-induced pulmonary toxicity in patients with disseminated testicular carcinoma. Oncology 41:4-7, 1984
    • (1984) Oncology , vol.41 , pp. 4-7
    • Van Barneweld, P.W.C.1    Sleiffer, D.T.2    Van der Mark, T.W.3
  • 47
    • 0027412053 scopus 로고
    • High-risk germ cell tumors in men. High response rate and severe toxicity with cisplatin, vinblastine, bleomycin, and etoposide
    • Blayney DW, Goldvert DA, Leong LA, et al: High-risk germ cell tumors in men. High response rate and severe toxicity with cisplatin, vinblastine, bleomycin, and etoposide. Cancer 71:2351-2357, 1993
    • (1993) Cancer , vol.71 , pp. 2351-2357
    • Blayney, D.W.1    Goldvert, D.A.2    Leong, L.A.3
  • 48
    • 0023096982 scopus 로고
    • Potentiation of ifosfamide neurotoxicity, hematotoxicity, and tubular nephrotoxicity by prior cis-diamminedichloroplatinum(II) therapy
    • Goren MP, Wright RK, Pratt CB, et al: Potentiation of ifosfamide neurotoxicity, hematotoxicity, and tubular nephrotoxicity by prior cis-diamminedichloroplatinum(II) therapy. Cancer Res 47:1457-1460, 1987
    • (1987) Cancer Res , vol.47 , pp. 1457-1460
    • Goren, M.P.1    Wright, R.K.2    Pratt, C.B.3
  • 49
    • 0025873424 scopus 로고
    • Ifosfamide, Fanconi's syndrome, and rickets
    • Pratt CB, Meyer WH, Jenkins JJ, et al: Ifosfamide, Fanconi's syndrome, and rickets. J Clin Oncol 9:1485-1499, 1991
    • (1991) J Clin Oncol , vol.9 , pp. 1485-1499
    • Pratt, C.B.1    Meyer, W.H.2    Jenkins, J.J.3
  • 50
    • 0021881114 scopus 로고
    • Ifosfamide - Pharmacology, safety and therapeutic potential
    • Brade WP, Herdrich K, Varini M: Ifosfamide - Pharmacology, safety and therapeutic potential. Cancer Treat Rev 12:1-47, 1985
    • (1985) Cancer Treat Rev , vol.12 , pp. 1-47
    • Brade, W.P.1    Herdrich, K.2    Varini, M.3
  • 52
    • 0020062041 scopus 로고
    • Severe nephrotoxicity: A probable complication of cis-dichlorodiammineplatinum(II) and cephalothin gentamicin therapy
    • Salem PA, Jabboury KW, Khalil MF: Severe nephrotoxicity: A probable complication of cis-dichlorodiammineplatinum(II) and cephalothin gentamicin therapy. Oncology 39:31-32, 1982
    • (1982) Oncology , vol.39 , pp. 31-32
    • Salem, P.A.1    Jabboury, K.W.2    Khalil, M.F.3
  • 54
    • 0024247625 scopus 로고
    • Long-term effects on renal function and blood pressure of treatment with cisplatin, vinblastine, and bleomycin in patients with germ cell cancer
    • Hansen SW, Groth S, Daugaard G, et al: Long-term effects on renal function and blood pressure of treatment with cisplatin, vinblastine, and bleomycin in patients with germ cell cancer. J Clin Oncol 6:1728-1731, 1988
    • (1988) J Clin Oncol , vol.6 , pp. 1728-1731
    • Hansen, S.W.1    Groth, S.2    Daugaard, G.3
  • 56
    • 0022160798 scopus 로고
    • Measurement of ethiofos (WR-2721) in plasma: Preliminary pharmacokinetics in the beagle
    • Swynnerton NF, Mangold DJ, Ludden TM: Measurement of ethiofos (WR-2721) in plasma: Preliminary pharmacokinetics in the beagle. J Liq Chromatogr 8:2675-2687, 1985
    • (1985) J Liq Chromatogr , vol.8 , pp. 2675-2687
    • Swynnerton, N.F.1    Mangold, D.J.2    Ludden, T.M.3
  • 57
    • 0022481189 scopus 로고
    • A method for the combined measurement of ethiofos and WR-1065 in plasma: Application to pharmacokinetic experiments with ethiofos and its metabolites
    • Swynnerton NF, Huelle BK, Mangold DJ: A method for the combined measurement of ethiofos and WR-1065 in plasma: Application to pharmacokinetic experiments with ethiofos and its metabolites. Int J Radiat Oncol Biol Phys 12:1495-1499, 1986
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1495-1499
    • Swynnerton, N.F.1    Huelle, B.K.2    Mangold, D.J.3
  • 60
    • 0002852243 scopus 로고
    • Pharmacokinetics of amifostine in cancer patients: Evidence for saturable metabolism
    • abstr
    • Shaw L, Bonner H, Nakashima H, et al: Pharmacokinetics of amifostine in cancer patients: Evidence for saturable metabolism. Proc Am Soc Clin Oncol 13:144, 1994 (abstr)
    • (1994) Proc am Soc Clin Oncol , vol.13 , pp. 144
    • Shaw, L.1    Bonner, H.2    Nakashima, H.3
  • 61
    • 0021914053 scopus 로고
    • Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721
    • Calabro-Jones PM, Fahey RC, Smoluk GD, et al: Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721. Int J Radiat Biol 47:23-27, 1985
    • (1985) Int J Radiat Biol , vol.47 , pp. 23-27
    • Calabro-Jones, P.M.1    Fahey, R.C.2    Smoluk, G.D.3
  • 62
    • 0023793476 scopus 로고
    • Radioprotection of cells in culture by WR-2721 and derivatives: Form of the drug responsible for protection
    • Smoluk GD, Fahey RC, Calabro-Jones PM, et al: Radioprotection of cells in culture by WR-2721 and derivatives: Form of the drug responsible for protection. Cancer Res 48:3641-3647, 1988
    • (1988) Cancer Res , vol.48 , pp. 3641-3647
    • Smoluk, G.D.1    Fahey, R.C.2    Calabro-Jones, P.M.3
  • 63
    • 0023679159 scopus 로고
    • Uptake of WR-2721 derivatives by cells in culture: Identification of the transported form of the drug
    • Calabro-Jones PM, Aguilera JA, Ward JF, et al: Uptake of WR-2721 derivatives by cells in culture: Identification of the transported form of the drug. Cancer Res 48:3634-3640, 1988
    • (1988) Cancer Res , vol.48 , pp. 3634-3640
    • Calabro-Jones, P.M.1    Aguilera, J.A.2    Ward, J.F.3
  • 64
    • 0000577297 scopus 로고
    • Biochemical determinants of the cytoprotective effect of amifostine
    • abstr 1725
    • Yang JL, Fernandes DJ, Speicher L, et al: Biochemical determinants of the cytoprotective effect of amifostine. Proc Am Assoc Cancer Res 36:290, 1995 (abstr 1725)
    • (1995) Proc Am Assoc Cancer Res , vol.36 , pp. 290
    • Yang, J.L.1    Fernandes, D.J.2    Speicher, L.3
  • 65
    • 0018839016 scopus 로고
    • Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
    • Yuhas JM: Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid. Cancer Res 40:1519-1524, 1980
    • (1980) Cancer Res , vol.40 , pp. 1519-1524
    • Yuhas, J.M.1
  • 66
    • 0026505855 scopus 로고
    • Effects of the modulating agent WR2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro in comparison to the effects of thiosulphate and diethyldithiocarbamate
    • Treskes M, Nijtmans LG, Fichtinger Schepman AMJ, et al: Effects of the modulating agent WR2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro in comparison to the effects of thiosulphate and diethyldithiocarbamate. Biochem Pharmacol 43:1013-1019, 1992
    • (1992) Biochem Pharmacol , vol.43 , pp. 1013-1019
    • Treskes, M.1    Nijtmans, L.G.2    Fichtinger Schepman, A.M.J.3
  • 67
    • 0026598335 scopus 로고
    • The reversal of cisplatin-protein interactions by the modulating agent WR2721 and its metabolites WR1065 and WR33278
    • Treskes M, Holwerda U, Nijtmans LGJ, et al: The reversal of cisplatin-protein interactions by the modulating agent WR2721 and its metabolites WR1065 and WR33278. Cancer Chemother Pharmacol 29:467-470, 1992
    • (1992) Cancer Chemother Pharmacol , vol.29 , pp. 467-470
    • Treskes, M.1    Holwerda, U.2    Nijtmans, L.G.J.3
  • 69
    • 0026559475 scopus 로고
    • Modification of radiation-induced carcinogenesis in mice by misonidazole and WR-2721
    • Hunter NR, Guttenberger R, Milas L: Modification of radiation-induced carcinogenesis in mice by misonidazole and WR-2721. Int J Radiat Oncol Biol Phys 22:795-798, 1992
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 795-798
    • Hunter, N.R.1    Guttenberger, R.2    Milas, L.3
  • 70
    • 0000593543 scopus 로고
    • In vitro study on the antioxidant activities of amifostine (WR-2721)
    • abstr 2503
    • Ohnishi ST, Ohnishi T, Click JH, et al: In vitro study on the antioxidant activities of amifostine (WR-2721). Proc Am Assoc Cancer Res 33:419, 1992 (abstr 2503)
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 419
    • Ohnishi, S.T.1    Ohnishi, T.2    Click, J.H.3
  • 71
    • 0000170555 scopus 로고
    • Anthracycline cardioprotection by amifostine (WR-2721) and its active metabolite (WR-1065) in vitro
    • abstr 435
    • Dorr RT, Lagel KE: Anthracycline cardioprotection by amifostine (WR-2721) and its active metabolite (WR-1065) in vitro. Proc Am Soc Clin Oncol 13:435, 1994 (abstr 435)
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 435
    • Dorr, R.T.1    Lagel, K.E.2
  • 72
    • 0019119832 scopus 로고
    • Treatment of tumours with the combination of WR-2721 and cis-dichlorodiammineplatinum (II) or cyclophosphamide
    • Yuhas JM, Spellman JM, Jordan SW: Treatment of tumours with the combination of WR-2721 and cis-dichlorodiammineplatinum (II) or cyclophosphamide. Br J Cancer 42:574-585, 1980
    • (1980) Br J Cancer , vol.42 , pp. 574-585
    • Yuhas, J.M.1    Spellman, J.M.2    Jordan, S.W.3
  • 77
    • 0043289892 scopus 로고
    • Amifostine does not inhibit the cytotoxic effects of a broad range of standard anticancer drugs against human ovarian and breast cancer cells
    • abstr 1727
    • Speicher LA, Krutzsh M, Wymer J, et al: Amifostine does not inhibit the cytotoxic effects of a broad range of standard anticancer drugs against human ovarian and breast cancer cells. Proc Am Assoc Cancer Res 36:290, 1995 (abstr 1727)
    • (1995) Proc Am Assoc Cancer Res , vol.36 , pp. 290
    • Speicher, L.A.1    Krutzsh, M.2    Wymer, J.3
  • 78
    • 0006963475 scopus 로고
    • WR-2721 chemoprotection of doxorubicin toxicity in mice
    • Green D, Wright A, Schein PS, et al: WR-2721 chemoprotection of doxorubicin toxicity in mice. Proc Am Assoc Cancer Res 33:490, 1992
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 490
    • Green, D.1    Wright, A.2    Schein, P.S.3
  • 79
    • 0026634982 scopus 로고
    • Improved therapeutic index of carboplatin plus cyclophosphamide versus cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer
    • Alberts DS, Green S, Hannigan EV, et al: Improved therapeutic index of carboplatin plus cyclophosphamide versus cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer. J Clin Oncol 10:706-717, 1992
    • (1992) J Clin Oncol , vol.10 , pp. 706-717
    • Alberts, D.S.1    Green, S.2    Hannigan, E.V.3
  • 80
    • 0017672542 scopus 로고
    • Cis-diamminedichloroplatinum, vinblastine and bleomycin combination chemotherapy in disseminated testicular cancer
    • Einhorn LH: Cis-diamminedichloroplatinum, vinblastine and bleomycin combination chemotherapy in disseminated testicular cancer. Ann Intern Med 87:293-298, 1977
    • (1977) Ann Intern Med , vol.87 , pp. 293-298
    • Einhorn, L.H.1
  • 81
    • 0028928599 scopus 로고
    • Anticancer drug renal toxicity and elimination: Dosing guidelines for altered renal function
    • Kintzel PE, Dorr RT: Anticancer drug renal toxicity and elimination: dosing guidelines for altered renal function. Cancer Treat Rev 21:33-64, 1995
    • (1995) Cancer Treat Rev , vol.21 , pp. 33-64
    • Kintzel, P.E.1    Dorr, R.T.2
  • 82
    • 0026652640 scopus 로고
    • Randomised study of two doses of cisplatin with cyclophosphamide in epithelial ovarian cancer
    • Kaye SB, Lewis CR, Paul J, et al: Randomised study of two doses of cisplatin with cyclophosphamide in epithelial ovarian cancer. Lancet 340:329-333, 1992
    • (1992) Lancet , vol.340 , pp. 329-333
    • Kaye, S.B.1    Lewis, C.R.2    Paul, J.3
  • 83
    • 0028274981 scopus 로고
    • A randomized, double-blind comparison of intravenous ondansetron alone and in combination with intravenous dexamethasone in the prevention of high-dose cisplatin-induced emesis
    • Hesketh PJ, Harvey WH, Harker WG, et al: A randomized, double-blind comparison of intravenous ondansetron alone and in combination with intravenous dexamethasone in the prevention of high-dose cisplatin-induced emesis. J Clin Oncol 12:596-600, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 596-600
    • Hesketh, P.J.1    Harvey, W.H.2    Harker, W.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.