Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Kim, Hye Yun ^a,b,c   Kim, Hyunjin V ^a,b   Yoon, Jin H ^a,d   Kang, Bo Ram ^a,b   Cho, Soo Min ^a,b   Lee, Sejin ^a,b   Kim, Ji Yoon ^a,b   Kim, Joo Won ^a,e   Cho, Yakdol ^a   Woo, Jiwan ^a   Kim, Young Soo ^a,b  

^a Korea Institute of Science and Technology   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Seoul National University   (South Korea)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e Dongduk Women's University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; DRINKING WATER; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; TAURINE;

ALZHEIMER DISEASE; ANIMAL; BRAIN; CELL CULTURE; COMPLICATION; DISEASE MODEL; ENZYME IMMUNOASSAY; GENETICS; HUMAN; LEARNING DISORDERS; MEMORY DISORDERS; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; BRAIN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRINKING WATER; HUMANS; IMMUNOENZYME TECHNIQUES; LEARNING DISORDERS; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; PRESENILIN-1; TAURINE;

EID: 84927610131     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep07467     Document Type: Article

References (48)

1. Kozauer, N. & Katz, R. Regulatory innovation and drug development for earlystage Alzheimer's disease. N Engl J Med 368, 1169-1171 doi:10.1056/ NEJMp1302513 (2013).
2. Aisen, P. S., Cummings, J. & Schneider, L. S. Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease. Cold Spring Harb Perspect Med 2, a006395 doi:10.1101/cshperspect.a006395 (2012).
3. Huxtable, R. J. Physiological actions of taurine. Physiol Rev 72, 101-163 (1992).
4. Frosini, M. et al. A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation. Br J Pharmacol 139, 487-494 doi:10.1038/sj.bjp.0705274 (2003).
5. Kumar, R. Role of naturally occurring osmolytes in protein folding and stability. Arch Biochem Biophys 491, 1-6 doi:10.1016/j.abb.2009.09.007 (2009).
6. Miao, J. et al. Taurine attenuates Streptococcus uberis-induced mastitis in rats by increasing T regulatory cells. Amino Acids 42, 2417-2428 doi:10.1007/s00726- 011-1047-3 (2012).
7. Schaffer, S. W., Azuma, J. & Madura, J. D. Mechanisms underlying taurinemediated alterations in membrane function. Amino Acids 8, 231-246 doi:10.1007/BF00806821 (1995).
8. Schaffer, S., Takahashi, K. & Azuma, J. Role of osmoregulation in the actions of taurine. Amino Acids 19, 527-546 (2000).
9. Su, J. H., Anderson, A. J., Cummings, B. J. & Cotman, C. W. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 5, 2529-2533 (1994).
10. Matsuyama, Y., Morita, T., Higuchi, M. & Tsujii, T. The effect of taurine administration on patients with acute hepatitis. Prog Clin Biol Res 125, 461-468 (1983).
11. Azuma, J. et al. Therapeutic effect of taurine in congestive heart failure: a doubleblind crossover trial. Clin Cardiol 8, 276-282 (1985).
12. Azuma, J., Sawamura, A. & Awata, N. Usefulness of taurine in chronic congestive heart failure and its prospective application. Jpn Circ J 56, 95-99 (1992).
13. Xu, Y. J., Arneja, A. S., Tappia, P. S. & Dhalla, N. S. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol 13, 57-65 (2008).
14. Vohra, B. P. & Hui, X. Improvement of impaired memory in mice by taurine. Neural Plast 7, 245-259 doi:10.1155/NP.2000.245 (2000).
15. Lu, C. L. et al. Taurine improves the spatial learning andmemory ability impaired by sub-chronic manganese exposure. J Biomed Sci 21, 51 doi:10.1186/1423-0127- 21-51 (2014).
16. Malcangio, M. et al. Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia. Psychopharmacology (Berl) 98, 316-320 (1989).
17. Su, Y. et al. Taurine improves functional and histological outcomes and reduces inflammation in traumatic brain injury. Neuroscience 266, 56-65 doi:10.1016/ j.neuroscience.2014.02.006 (2014).
18. Suge, R. et al. Specific timing of taurine supplementation affects learning ability in mice. Life Sci 81, 1228-1234 doi:10.1016/j.lfs.2007.08.028 (2007).
19. Javed, H. et al. Taurine ameliorates neurobehavioral, neurochemical and immunohistochemical changes in sporadic dementia of Alzheimer's type (SDAT) caused by intracerebroventricular streptozotocin in rats. Neurol Sci 34, 2181-2192 doi:10.1007/s10072-013-1444-3 (2013).
20. Ito, K., Arko, M., Kawaguchi, T., Kuwahara, M. & Tsubone, H. The effect of subacute supplementation of taurine on spatial learning and memory. Exp Anim 58, 175-180 (2009).
21. Santa-Maria, I., Hernandez, F., Moreno, F. J. & Avila, J. Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-beta-peptide aggregation. Neurosci Lett 429, 91-94 doi:10.1016/j.neulet.2007.09.068 (2007).
22. Pan, C., Prentice, H., Price, A. L. & Wu, J. Y. Beneficial effect of taurine on hypoxia- and glutamate-induced endoplasmic reticulum stress pathways in primary neuronal culture. Amino Acids 43, 845-855 doi:10.1007/s00726-011- 1141-6 (2012).
23. Louzada, P. R. et al. Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders. FASEB J 18, 511-518 doi:10.1096/fj.03-0739com (2004).
24. Wu, J. et al. Taurine activates glycine and gamma-aminobutyric acid A receptors in rat substantia gelatinosa neurons. Neuroreport 19, 333-337 doi:10.1097/ WNR.0b013e3282f50c90 (2008).
25. Paula-Lima, A. C., De Felice, F. G., Brito-Moreira, J. & Ferreira, S. T. Activation of GABA(A) receptors by taurine and muscimol blocks the neurotoxicity of betaamyloid in rat hippocampal and cortical neurons. Neuropharmacology 49, 1140-1148 doi:10.1016/j.neuropharm.2005.06.015 (2005).
26. Sun, Q. et al. Taurine attenuates amyloid beta 1-42-induced mitochondrial dysfunction by activating of SIRT1 in SK-N-SH cells. Biochem Biophys Res Commun 447, 485-489 doi:10.1016/j.bbrc.2014.04.019 (2014).
27. Martorana, A., Di Lorenzo, F., Manenti, G., Semprini, R. & Koch, G. Homotaurine induces measurable changes of short latency afferent inhibition in a group ofmild cognitive impairment individuals. Front Aging Neurosci 6, 254 doi:10.3389/ fnagi.2014.00254 (2014).
28. Jankowsky, J. L. et al. Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. Biomol Eng 17, 157-165 (2001).
29. Filali, M., Lalonde, R. & Rivest, S. Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer's disease. Genes Brain Behav 8, 143-148 doi:10.1111/j.1601-183X.2008.00453.x (2009).
30. Maia, L. F. et al. Changes in amyloid-beta and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein. Sci Transl Med 5, 194re192 doi:10.1126/scitranslmed.3006446 (2013).
31. Rodrigue, K. M. et al. beta-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology 78, 387-395 doi:10.1212/ WNL.0b013e318245d295 (2012).
32. Gervais, F. et al. Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis. Neurobiol Aging 28, 537-547 doi:10.1016/ j.neurobiolaging.2006.02.015 (2007).
33. Tapiola, T. et al. Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol 66, 382-389 doi:10.1001/archneurol.2008.596 (2009).
34. Sofroniew, M. V. Reactive astrocytes in neural repair and protection. Neuroscientist 11, 400-407 doi:10.1177/1073858405278321 (2005).
35. Pike, C. J., Cummings, B. J. & Cotman, C. W. Early association of reactive astrocytes with senile plaques in Alzheimer's disease. Exp Neurol 132, 172-179 (1995).
36. El Idrissi, A. Taurine improves learning and retention in aged mice. Neurosci Lett 436, 19-22 doi:10.1016/j.neulet.2008.02.070 (2008).
37. Sun, M., Gu, Y., Zhao, Y. & Xu, C. Protective functions of taurine against experimental stroke through depressing mitochondria-mediated cell death in rats. Amino Acids 40, 1419-1429 doi:10.1007/s00726-010-0751-8 (2011).
38. Sun, M., Zhao, Y., Gu, Y. & Xu, C. Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-kappaB. Amino Acids 42, 1735-1747 doi:10.1007/s00726-011-0885-3 (2012).
39. Kim, H. Y., Kim, Y., Han, G. & Kim, D. J. Regulation of in vitro Abeta1-40 aggregation mediated by small molecules. J Alzheimers Dis 22, 73-85 doi:10.3233/ JAD-2010-100183 (2010).
40. Fraser, P. E., Nguyen, J. T., Chin, D. T. & Kirschner, D. A. Effects of sulfate ions on Alzheimer beta/A4 peptide assemblies: implications for amyloid fibrilproteoglycan interactions. J Neurochem 59, 1531-1540 (1992).
41. Aisen, P. S. et al. Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study). Arch Med Sci 7, 102-111 doi:10.5114/aoms.2011.20612 (2011).
42. Alford, C., Cox, H. & Wescott, R. The effects of red bull energy drink on human performance and mood. Amino Acids 21, 139-150 (2001).
43. Aggarwal, R., Mishra, A., Crochet, P., Sirimanna, P. & Darzi, A. Effect of caffeine and taurine on simulated laparoscopy performed following sleep deprivation. Br J Surg 98, 1666-1672 doi:10.1002/bjs.7600 (2011).
44. Olive, M. F. Interactions between taurine and ethanol in the central nervous system. Amino Acids 23, 345-357 doi:10.1007/s00726-002-0203-1 (2002).
45. Dunah, A. W. et al. Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science 296, 2238-2243 doi:10.1126/science.1072613 (2002).
46. Liu, L. & Duff, K. A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse. J Vis Exp doi:10.3791/960 (2008).
47. Li, Z., Herrmann, K. & Pohlenz, F. Lateral scanning confocal microscopy for the determination of in-plane displacements of microelectromechanical systems devices. Opt Lett 32, 1743-1745 (2007).
48. Paxinos, G. & Franklin, B. J. TheMouse Brain in Stereotaxic Coordinates. 2nd edn, (Academic Press, 2001).