Synthesis and biological evaluation of sophoridinol derivatives as a novel family of potential anticancer agents

ACS Medicinal Chemistry Letters

Volumn 5, Issue 11, 2014, Pages 1225-1229

  Bi, Chongwen ^a   Zhang, Caixia ^a   Li, Yinghong ^a   Tang, Sheng ^a   Wang, Shenggang ^b   Shao, Rongguang ^a   Fu, Haigen ^a   Su, Feng ^b   Song, Danqing ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^b QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

antiproliferative; drug resistance; Sophoridine; sophoridinol; structure activity relationship

Indexed keywords

ANTINEOPLASTIC AGENT; PLANT MEDICINAL PRODUCT;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DRUG HALF LIFE; DRUG MECHANISM; DRUG SYNTHESIS; G1 PHASE CELL CYCLE CHECKPOINT; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MEAN RESIDENCE TIME; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; STRUCTURE ACTIVITY RELATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

RATTUS;

EID: 84927608129     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml500289h     Document Type: Article

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