Toll-like receptor 8 deletion accelerates autoimmunity in a mouse model of lupus through a Toll-like receptor 7-dependent mechanism

Immunology

Volumn 145, Issue 1, 2015, Pages 60-70

  Tran, Ngoc Lan ^a   Manzin Lorenzi, Céline ^a   Santiago Raber, Marie Laure ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Monocytes; Systemic lupus erythematosus; Toll like receptors

Indexed keywords

TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; ANTINUCLEAR ANTIBODY; HLA ANTIGEN CLASS 2; MEMBRANE PROTEIN; TLR7 PROTEIN, MOUSE; TLR8 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GENE DELETION; GENE DOSAGE; GENE DUPLICATION; GENE LOCUS; GENE MUTATION; GLOMERULONEPHRITIS; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MONOCYTE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLENOMEGALY; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; UPREGULATION; X CHROMOSOME; ANIMAL; DEFICIENCY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; ANTIBODIES, ANTINUCLEAR; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS II; LUPUS ERYTHEMATOSUS, SYSTEMIC; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MONOCYTES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 84927594892     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12426     Document Type: Article

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