Universal newborn screening for congenital CMV infection: What is the evidence of potential benefit?

Reviews in Medical Virology

Volumn 24, Issue 5, 2014, Pages 291-307

  Cannon, Michael J ^a   Griffiths, Paul D ^b   Aston, Van ^c   Rawlinson, William D ^d,e  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c EMORY UNIVERSITY   (United States)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e New South Wales Government   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONGENITAL INFECTION; CYTOMEGALOVIRUS INFECTION; DISEASE CLASSIFICATION; HEARING IMPAIRMENT; HUMAN; INCIDENCE; NEWBORN; NEWBORN PERIOD; NEWBORN SCREENING; OCCUPATIONAL THERAPY; PHYSIOTHERAPY; PUBLIC HEALTH SERVICE; SPECIAL EDUCATION; VISUAL IMPAIRMENT; COMPLICATION; CYTOMEGALOVIRUS INFECTIONS; VIROLOGY;

CYTOMEGALOVIRUS INFECTIONS; HUMANS; INFANT, NEWBORN; NEONATAL SCREENING;

EID: 84927575980     PISSN: 10529276     EISSN: 10991654     Source Type: Journal    
DOI: 10.1002/rmv.1790     Document Type: Article

References (111)

1. Cannon MJ, Davis KF. Washing our hands of the congenital cytomegalovirus disease epidemic. BMC Public Health 2005; 5: 70.
2. Griffiths PD, Walter S. Cytomegalovirus. Current Opinion in Infectious Diseases 2005; 18: 241-245.
3. McMullan BJ, Palasanthiran P, Jones CA, et al. Congenital cytomegalovirus-time to diagnosis, management and clinical sequelae in Australia: opportunities for earlier identification. Medical Journal of Australia 2011; 194: 625-629.
4. Cannon MJ. Congenital cytomegalovirus (CMV) epidemiology and awareness. Journal of Clinical Virology 2009; 46S: S6-S10.
5. Institute of Medicine Committee to Study Priorities for Vaccine D. Vaccines for the 21st Century: A Tool for Decision Making. National Academy Press: Washington D.C., 2000.
6. Yow MD, Demmler GJ. Congenital cytomegalovirus disease-20years is long enough. New England Journal of Medicine 1992; 326: 702-703.
7. Demmler-Harrison GJ. Congenital cytomegalovirus: public health action towards awareness, prevention, and treatment. Journal of Clinical Virology 2009; 46: S1-S5.
8. de Vries JJC, Vossen A, Kroes ACM, van der Zeijst BAM. Implementing neonatal screening for congenital cytomegalovirus: addressing the deafness of policy makers. Reviews in Medical Virology 2011; 21: 54-61.
9. Grosse SD, Dollard S, Ross DS, Cannon M. Newborn screening for congenital cytomegalovirus: options for hospital-based and public health programs. Journal of Clinical Virology 2009; 46: S32-S36.
10. Revello MG, Gerna G. Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant. Clinical Microbiology Reviews 2002; 15: 680-715.
11. Lazzarotto T. The best practices for screening, monitoring, and diagnosis of cytomegalovirus disease, part II. Clinical Microbiology Newsletter 2010; 32: 9-15.
12. Pass RF, Zhang C, Evans A, et al. Vaccine prevention of maternal cytomegalovirus infection. New England Journal of Medicine 2009; 360: 1191-1199.
13. Sung H, Schleiss MR. Update on the current status of cytomegalovirus vaccines. Expert Review of Vaccines 2010; 9: 1303-1314.
14. Picone O, Vauloup-Fellous C, Cordier AG, et al. A 2-year study on cytomegalovirus infection during pregnancy in a French hospital. BJOG: An International Journal of Obstetrics & Gynaecology 2009; 116: 818-823.
15. Vauloup-Fellous C, Picone O, Cordier A-G, et al. Does hygiene counseling have an impact on the rate of CMV primary infection during pregnancy? Results of a 3-year prospective study in a French hospital. Journal of Clinical Virology 2009; 46S: S49-S53.
16. Adler SP, Finney JW, Manganello AM, Best AM. Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors: a randomized controlled trial. The Pediatric Infectious Disease Journal 1996; 15: 240-246.
17. Jacquemard F, Yamamoto M, Costa JM, et al. Maternal administration of valaciclovir in symptomatic intrauterine cytomegalovirus infection. BJOG 2007; 114: 1113-1121.
18. Nigro G, Adler SP, La Torre R, Best AM. Passive immunization during pregnancy for congenital cytomegalovirus infection. New England Journal of Medicine 2005; 353: 1350-1362.
19. Kimberlin DW, Acosta EP, Sanchez PJ, et al. Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease. Journal of Infectious Diseases 2008; 197: 836-845.
20. Kimberlin DW, Lin CY, Sanchez PJ, et al. Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial. Journal of Pediatrics 2003; 143: 16-25.
21. Whitley RJ, Cloud G, Gruber W, et al. Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Journal of Infectious Diseases 1997; 175: 1080-1086.
22. Mocarski Jr. ES, Shenk T, Pass RF. Cytomegaloviruses. In Fields' Virology, 5th edn, Knipe DM, Howley PM (eds). Lippincott Williams & Wilkins: Philadelphia, 2007; 2702-2772.
23. Stagno S, Remington JS, Klein JO. Cytomegalovirus. In Infectious diseases of the fetus and newborn infant, Remington JS, Klein JO (eds). W.B. Saunders Company: Philadelphia, 2001; 389-424.
24. Schleiss MR. Role of breast milk in acquisition of cytomegalovirus infection: recent advances. Current Opinion in Pediatrics 2006; 18: 48-52.
25. Istas AS, Demmler GJ, Dobbins JG, Stewart JA. Surveillance for congenital cytomegalovirus disease: a report from the National Congenital Cytomegalovirus Disease Registry. Clinical Infectious Diseases 1995; 20: 665-670.
26. Iwasenko JM, Howard J, Arbuckle S, et al. Human cytomegalovirus infection is detected frequently in stillbirths and is associated with fetal thrombotic vasculopathy. Journal of Infectious Diseases 2011; 203: 1526-1533.
27. Wilson JMG, Jungner G. Principles and practice of mass screening for disease. Boletin De La Oficina Sanitaria Panamericana 1968; 65: 281-393.
28. Calonge N, Green NS, Rinaldo P, et al. Committee report: method for evaluating conditions nominated for population-based screening of newborns and children. Genetics in Medicine 2010; 12: 153-159.
29. Watson MS, Mann MY, Lloyd-Puryear MA, Rinaldo P, Howell RR. American College of Medical Genetics Newborn Screening Expert Group. Newborn screening: toward a uniform screening panel and system -executive summary. (Vol. 117, pg S296-307). Pediatrics 2006; 117: 851-851.
30. Centers for Disease C, Prevention. Impact of expanded newborn screening-United States, 2006. MMWR. Morbidity and Mortality Weekly Report 2008; 57: 1012-1015.
31. Fowler KB, Dahle AJ, Boppana SB, Pass RF. Newborn hearing screening: will children with hearing loss caused by congenital cytomegalovirus infection be missed? Journal of Pediatrics 1999; 135: 60-64.
32. Din ES, Brown CJ, Grosse SD, et al. Attitudes toward newborn screening for cytomegalovirus infection. Pediatrics 2011; 128: e1434-1442.
33. Koyano S, Inoue N, Oka A, et al. Screening for congenital cytomegalovirus infection using newborn urine samples collected on filter paper: feasibility and outcomes from a multicentre study. BMJ Open 2011; 1: e000118.
34. Boppana SB, Ross SA, Novak Z, et al. Dried blood spot real-time polymerase chain reaction assays to screen newborns for congenital cytomegalovirus infection. JAMA 2010; 303: 1375-1382.
35. Boppana SB, Ross SA, Shimamura M, et al. Saliva polymerase-chain-reaction assay for cytomegalovirus screening in newborns. New England Journal of Medicine 2011; 364: 2111-2118.
36. Kharrazi M, Hyde T, Young S, Amin MM, Cannon MJ, Dollard SC. Use of screening dried blood spots for estimation of prevalence, risk factors, and birth outcomes of congenital cytomegalovirus infection. Journal of Pediatrics 2010; 157: 191-197.
37. Barbi M, Binda S, Caroppo S, Primache V. Neonatal screening for congenital cytomegalovirus infection and hearing loss. Journal of Clinical Virology 2006; 35: 206-209.
38. Howard J, Hall B, Brennan LE, et al. Utility of newborn screening cards for detecting CMV infection in cases of stillbirth. Journal of Clinical Virology 2009; 44: 215-218.
39. Gurian EA, Kinnamon DD, Henry JJ, Waisbren SE. Expanded newborn screening for biochemical disorders: the effect of a false-positive result. Pediatrics 2006; 117: 1915-1921.
40. Woolf SH, Harris R. The harms of screening: new attention to an old concern. JAMA 2012; 307: 565-566.
41. Douglas CMW, van El CG, Faulkner A, Cornel MC. Governing biological material at the intersection of care and research: the use of dried blood spots for biobanking. Croatian Medical Journal 2012; 53: 390-397.
42. Bailey DB, Jr. Newborn screening for fragile X syndrome. Mental Retardation and Developmental Disabilities Research Reviews 2004; 10: 3-10.
43. Harrell H. Currents in contemporary ethics the role of parents in expanded newborn screening. The Journal of Law, Medicine & Ethics 2009; 37: 846-851.
44. Knott M, Leonard H, Downs J. The diagnostic odyssey to Rett syndrome: the experience of an Australian family. American Journal of Medical Genetics Part A 2012; 158A: 10-12.
45. Busson L, Van den Wijngaert S, Dahma H, et al. Evaluation of 10 serological assays for diagnosing Mycoplasma pneumoniae infection. Diagnostic Microbiology and Infectious Disease 2013; 76: 133-137.
46. Dollard SC, Grosse SD, Ross DS. New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Reviews in Medical Virology 2007; 17: 355-363.
47. Morita M, Morishima T, Yamazaki T, Chiba S, Kawana T. Clinical survey of congenital cytomegalovirus infection in Japan. Acta Paediatrica Japonica 1998; 40: 432-436.
48. Townsend CL, Peckham CS, Tookey PA. Surveillance of congenital cytomegalovirus in the UK and Ireland. Archives of Disease in Childhood. Fetal and Neonatal 2011; 96: F398-F403.
49. Buchheit J, Marshall GS, Rabalais GP, Dobbins GJ. Congenital cytomegalovirus disease in the Louisville area: a significant public health problem. Journal of the Kentucky Medical Association 1994; 92: 411-415.
50. Ahlfors K, Ivarsson SA, Harris S. Report on a long-term study of maternal and congenital cytomegalovirus infection in Sweden. Review of prospective studies available in the literature. Scandinavian Journal of Infectious Diseases 1999; 31: 443-457.
51. Leung J, Cannon MJ, Grosse SD, Bialek SR. Laboratory testing and diagnostic coding for cytomegalovirus among privately insured infants in the United States: a retrospective study using administrative claims data. BMC Pediatrics 2013; 13: 90-90.
52. Boyle CA, Murphy CC. Neurodevelopmental disabilities. In Neuroepidemiology: From Principles to Practice, Nelson LM, Tanner CM, Van Den Eeden SK, McGuire VM (eds). Oxford University Press: Oxford, 2004; 360-383.
53. Harris RP, Helfand M, Woolf SH, et al. Current methods of the US Preventive Services Task Force-a review of the process. American Journal of Preventive Medicine 2001; 20: 21-35.
54. Kennedy CR, McCann DC, Campbell MJ, et al. Language ability after early detection of permanent childhood hearing impairment. New England Journal of Medicine 2006; 354: 2131-2141.
55. Drews CD, Yeargin-Allsopp M, Murphy CC, Decoufle P. Hearing impairment among 10-year-old children: metropolitan Atlanta, 1985 through 1987. American Journal of Public Health 1994; 84: 1164-1166.
56. Harrison M, Roush J. Age of suspicion, identification, and intervention for infants and young children with hearing loss: a national study. Ear and Hearing 1996; 17: 55-62.
57. Nelson HD, Bougatsos C, Nygren P. Universal newborn hearing screening: systematic review to update the 2001 US Preventive Services Task Force recommendation. Pediatrics 2008; 122: E266-E276.
58. Smith RJ, Bale JF, Jr., White KR. Sensorineural hearing loss in children. Lancet 2005; 365: 879-890.
59. Stacey PC, Fortnum HA, Barton GR, Summerfield AQ. Hearing-impaired children in the United Kingdom, I: auditory performance, communication skills, educational achievements, quality of life, and cochlear implantation. Ear Hearing 2006; 27: 161-186.
60. Nicholas JG, Geers AE. Will they catch up? The role of age at cochlear implantation in the spoken language development of children with severe to profound hearing loss. Journal of Speech, Language, and Hearing Research 2007; 50: 1048-1062.
61. Niparko JK, Tobey EA, Thal DJ, et al. Spoken language development in children following cochlear implantation. JAMA 2010; 303: 1498-1506.
62. Geers AE. Speech, language, and reading skills after early cochlear implantation. Archives of Otolaryngology - Head and Neck Surgery 2004; 130: 634-638.
63. Kileny PR, Zwolan TA, Ashbaugh C. The influence of age at implantation on performance with a cochlear implant in children. Otology & Neurotology 2001; 22: 42-46.
64. Kylat RI, Kelly EN, Ford-Jones EL. Clinical findings and adverse outcome in neonates with symptomatic congenital cytomegalovirus (SCCMV) infection. European Journal of Pediatrics 2006; 165: 773-778.
65. Leonard H, Wen XY. The epidemiology of mental retardation: challenges and opportunities in the new millennium. Mental Retardation and Developmental Disabilities Research Reviews 2002; 8: 117-134.
66. Fowler KB, Pass RF, Boppana S, Britt WJ. Neurodevelopmental deficits in school-aged children who have asymptomatic congenital cytomegalovirus infection. Paediatric and Perinatal Epidemiology 1999; 13: A19-20.
67. Kashden J, Frison S, Fowler K, Pass RF, Boll TJ. Intellectual assessment of children with asymptomatic congenital cytomegalovirus infection. Journal of Developmental and Behavioral Pediatrics 1998; 19: 254-259.
68. Temple RO, Pass RF, Boll TJ. Neuropsychological functioning in patients with asymptomatic congenital cytomegalovirus infection. Journal of Developmental and Behavioral Pediatrics 2000; 21: 417-422.
69. Williamson WD, Percy AK, Yow MD, et al. Asymptomatic congenital cytomegalovirus infection. Audiologic, neuroradiologic, and neurodevelopmental abnormalities during the first year. American Journal of Diseases of Children 1990; 144: 1365-1368.
70. Zhang XW, Li F, Yu XW, Shi XW, Shi J, Zhang JP. Physical and intellectual development in children with asymptomatic congenital cytomegalovirus infection: a longitudinal cohort study in Qinba mountain area, China. Journal of Clinical Virology 2007; 40: 180-185.
71. Cazacu AC, Chung S, Greisser C, et al. Neurodevelopmental outcome at elementary school age of children born with asymptomatic congenital cytomegalovirus infection. Pediatric Research 2004; 55: 319A-319A.
72. Conboy TJ, Pass RF, Stagno S, et al. Intellectual development in school-aged children with asymptomatic congenital cytomegalovirus infection. Pediatrics 1986; 77: 801-806.
73. Shan RB, Wang XL, Fu P. Growth and development of infants with asymptomatic congenital cytomegalovirus infection. Yonsei Medical Journal 2009; 50: 667-671.
74. Lipkin PH, Daniel J, Desch LW, et al. Role of the medical home in family-centered early intervention services. Pediatrics 2007; 120: 1153-1158.
75. Hix-Small H, Marks K, Squires J, Nickel R. Impact of implementing developmental screening at 12 and 24months in a pediatric practice. Pediatrics 2007; 120: 381-389.
76. Schonwald A, Huntington N, Chan E, Risko W, Bridgemohan C. Routine developmental screening implemented in urban primary care settings: more evidence of feasibility and effectiveness. Pediatrics 2009; 123: 660-668.
77. King TM, Tandon SD, Macias MM, et al. Implementing developmental screening and referrals: lessons learned from a national project. Pediatrics 2010; 125: 350-360.
78. Dawson G, Rogers S, Munson J, et al. Randomized, controlled trial of an intervention for toddlers with autism: the early start Denver model. Pediatrics 2010; 125: E17-E23.
79. Del Giudice E, Titomanlio L, Brogna G, et al. Early intervention for children with Down syndrome in southern Italy-the role of parent-implemented developmental training. Infants Young Children 2006; 19: 50-58.
80. Fey ME, Warren SF, Brady N, et al. Early effects of responsivity education/prelinguistic milieu teaching for children with developmental delays and their parents. Journal of Speech, Language, and Hearing Research 2006; 49: 526-547.
81. Guralnick MJ. Effectiveness of early intervention for vulnerable children: a developmental perspective. American Journal on Mental Retardation 1998; 102: 319-345.
82. Tang MH, Lin CK, Lin WH, Chen CH, Tsai SW, Chang YY. The effect of adding a home program to weekly institutional-based therapy for children with undefined developmental delay: a pilot randomized clinical trial. Journal of the Chinese Medical Association 2011; 74: 259-266.
83. Thomaidis L, Kaderoglou E, Stefou M, Damianou S, Bakoula C. Does early intervention work? A controlled trial. Infants Young Children 2000; 12: 17-22.
84. van der Schuit M, Segers E, van Balkom H, Verhoeven L. Early language intervention for children with intellectual disabilities: a neurocognitive perspective. Research in Developmental Disabilities 2011; 32: 705-712.
85. Oliver SE, Cloud GA, Sanchez PJ, et al. Neurodevelopmental outcomes following ganciclovir therapy in symptomatic congenital cytomegalovirus infections involving the central nervous system. Journal of Clinical Virology 2009; 46: S22-S26.
86. Boppana S, Amos C, Britt W, Stagno S, Alford C, Pass R. Late onset and reactivation of chorioretinitis in children with congenital cytomegalovirus infection. The Pediatric Infectious Disease Journal 1994; 13: 1139-1142.
87. Brubaker JW, Bale JF, Jr., Ampofo K, Dries DC. Congenital cytomegalovirus infection: progressive postnatal chorioretinitis. Journal of Pediatric Ophthalmology and Strabismus 2009; 46: 249-251.
88. Anderson KS, Amos CS, Boppana S, Pass R. Ocular abnormalities in congenital cytomegalovirus infection. Journal of the American Optometric Association 1996; 67: 273-278.
89. Britt WJ. Cytomegalovirus. In Infectious Disease of the Fetus and Newborn Infant, 7th edn, Remington JS, Klein JO, Wilson CB, Nizet V, Maldonado YA (eds). Elsevier Saunders: Philadelphia, 2011; 706-755.
90. Coats DK, Demmler GJ, Paysse EA, Du LT, Libby C. Ophthalmologic findings in children with congenital cytomegalovirus infection. Journal of AAPOS 2000; 4: 110-116.
91. Wasserman RC, Croft CA, Brotherton SE. Preschool vision screening in pediatric practice: a study from the pediatric research in office settings (PROS) network. Pediatrics 1992; 89: 834-838.
92. Kemper AR, Wallace DK, Patel N, Crews JE. Preschool vision testing by health providers in the United States: FINDINGS from the 2006-2007 Medical Expenditure Panel Survey. Journal of AAPOS 2011; 15: 480-483.
93. Sonksen PM, Petrie A, Drew KJ. Promotion of visual development of severely visually-impaired babies: evaluation of a developmentally based program. Developmental Medicine and Child Neurology 1991; 33: 320-335.
94. Vervloed MPJ, Janssen N, Knoors H. Visual rehabilitation of children with visual impairments. Journal of Developmental and Behavioral Pediatrics 2006; 27: 493-506.
95. Lalezary M, Recchia FM, Kim SJ. Treatment of congenital cytomegalovirus retinitis with intravitreous ganciclovir. Archives of Ophthalmology 2012; 130: 525-527.
96. Centers for Disease C, Prevention. CDC grand rounds: newborn screening and improved outcomes. MMWR. Morbidity and Mortality Weekly Report 2012; 61: 390-393.
97. Kadambari S, Williams EJ, Luck S, Griffiths PD, Sharland M. Evidence based management guidelines for the detection and treatment of congenital CMV. Early Human Development 2011; 87: 723-728.
98. Joint Comm Infant H. Clarification for year 2007 JCIH position statement, 2007.
99. Sharon B, Schleiss MR. Congenital cytomegalovirus infection: an unrecognized epidemic. Infection Medicine 2007; 24: 402-415.
100. Dollard SC, Schleiss MR, Grosse SD. Public health and laboratory considerations regarding newborn screening for congenital cytomegalovirus. Journal of Inherited Metabolic Disease 2010; 33: S249-S254.
101. Roser D, Nielsen HV, Petersen E, Saugmann-Jensen P, Norgaard-Pedersen PB. Congenital toxoplasmosis-a report on the Danish neonatal screening programme 1999-2007. Journal of Inherited Metabolic Disease 2010; 33: S241-S247.
102. Grosse SD, Boyle CA, Kenneson A, Khoury MJ, Wilfond BS. From public health emergency to public health service: the implications of evolving criteria for newborn screening panels. Pediatrics 2006; 117: 923-929.
103. Ross LF. Mandatory versus voluntary consent for newborn screening? Kennedy Institute of Ethics Journal 2010; 20: 299-328.
104. Moyer VA, Calonge N, Teutsch SM, Botkin JR, Force USPST. Expanding newborn screening: process, polity, and priorities. Hastings Center Report 2008; 38: 32-39.
105. Office for National Statistics. Review of the national statistician on births and patterns of family building in England and Wales, 2008.
106. Martin JA, Hamilton BE, Sutton PD, Ventura SJ, Mathews TJ, Osterman MJK. Births: final data for 2008. National vital statistics reports: from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System 2010; 59: 3-71.
107. Foulon I, Naessens A, Foulon W, Casteels A, Gordts F. A 10-year prospective study of sensorineural hearing loss in children with congenital cytomegalovirus infection. Journal of Pediatrics 2008; 153: 84-88.
108. Paradiz KR, Seme K, Puklavec E, Paro-Panjan D, Poljak M. Prevalence of congenital cytomegalovirus infection in Slovenia: a study on 2841 newborns. Journal of Medical Virology 2012; 84: 109-115.
109. Foulon I, Naessens A, Faron G, Foulon W, Jansen AC, Gordts F. Hearing thresholds in children with a congenital CMV infection: a prospective study. International Journal of Pediatric Otorhinolaryngology 2012; 76: 712-717.
110. Boppana SB, Fowler KB, Britt WJ, Stagno S, Pass RF. Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus. Pediatrics 1999; 104: 55-60.
111. Saigal S, Lunyk O, Larke RP, Chernesky MA. The outcome in children with congenital cytomegalovirus infection. A longitudinal follow-up study. American Journal of Diseases of Children 1982; 136: 896-901.