Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia

Cell Cycle

Volumn 13, Issue 19, 2014, Pages 3076-3082

  Ehrlich, Lori A ^a,b   Yang Iott, Katherine ^a,b   Bassing, Craig H ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

ATM; BCL11B; T ALL; Thymocytes; Transformation; Translocations

Indexed keywords

ATM PROTEIN; ATM PROTEIN, MOUSE; BCL11B PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; REPRESSOR PROTEIN; TCL1 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BCL11B GENE; CANCER SUSCEPTIBILITY; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; GENE DOSAGE; GENE INACTIVATION; GENE LOCUS; GENETIC PREDISPOSITION; GENETIC RECOMBINATION; GENOTYPE; HAPLOINSUFFICIENCY; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; SPLEEN CELL; T LYMPHOCYTE RECEPTOR GENE; THYMOCYTE; THYMUS LYMPHOMA; TUMOR SUPPRESSOR GENE; ALLELE; ANIMAL; C57BL MOUSE; CHROMOSOME; DEFICIENCY; FLOW CYTOMETRY; GENE TRANSLOCATION; GENETICS; HUMAN; KARYOTYPING; KNOCKOUT MOUSE; METABOLISM; METAPHASE; PATHOLOGY; PHENOTYPE;

MUS;

ALLELES; ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CHROMOSOMES; FLOW CYTOMETRY; HUMANS; KARYOTYPING; METAPHASE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; REPRESSOR PROTEINS; TRANSLOCATION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84927557120     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2014.949144     Document Type: Article

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