Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Wee, Yin Shen ^a   Weis, Janis J ^a   Gahring, Lorise C ^a,b   Rogers, Scott W ^b,c   Weis, John H ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

^c Department of Internal Medicine Division of Geriatrics University of Utah School of Medicine ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GLUCOSE; IFITM PROTEIN; INSULIN; INTERFERON; INTERLEUKIN 10; LEPTIN; LEPTIN RECEPTOR; NEUROPEPTIDE; NUCLEAR FACTOR Y; POMC NEUROPEPTIDE; UNCLASSIFIED DRUG; CYTOKINE; DIFFERENTIATION ANTIGEN; LEU-13 ANTIGEN; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; FAT MASS; GENE; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; IFITM GENE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; METABOLIC DISORDER; MICROGLIA; MOUSE; NONHUMAN; OBESITY; ONSET AGE; PHENOTYPE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; WEIGHT GAIN; ANIMAL; BLOOD; GENE DELETION; GENETICS; HYPOTHALAMUS; METABOLISM; MULTIGENE FAMILY; PATHOLOGY; PHYSIOLOGY;

ANIMALIA; MUS;

AGE OF ONSET; ANIMALS; ANTIGENS, DIFFERENTIATION; CYTOKINES; GENE DELETION; GENE EXPRESSION PROFILING; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LEPTIN; METABOLIC NETWORKS AND PATHWAYS; MICE; MICROGLIA; MULTIGENE FAMILY; NEUROPEPTIDE Y; OBESITY; PRO-OPIOMELANOCORTIN;

EID: 84927539363     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123218     Document Type: Article

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