KPC1-mediated ubiquitination and proteasomal processing of nf-κb1 p105 to p50 restricts tumor growth

Cell

Volumn 161, Issue 2, 2015, Pages 333-347

  Kravtsova Ivantsiv, Yelena ^a   Shomer, Inna ^a   Cohen Kaplan, Victoria ^a   Snijder, Berend ^b   Superti Furga, Giulio ^b   Gonen, Hedva ^a   Sommer, Thomas ^c   Ziv, Tamar ^a   Admon, Arie ^a   Naroditsky, Inna ^d   Jbara, Muhammad ^e   Brik, Ashraf ^a,e   Pikarsky, Eli ^f   Kwon, Yong Tae ^g   Doweck, Ilana ^h   Ciechanover, Aaron ^a,g  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d Rambam Health Care Campus ^*  (Israel)

^e BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^f HEBREW UNIVERSITY   (Israel)

^g Seoul National University   (South Korea)

^h CARMEL MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; HOMODIMER; LIGASE; PROTEASOME; PROTEIN KPC1; PROTEIN P105; PROTEIN P50; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; UNCLASSIFIED DRUG; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NFKB1 PROTEIN, HUMAN; RNF123 PROTEIN, HUMAN; SIGNAL PEPTIDE; TUMOR SUPPRESSOR PROTEIN; UBAC1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; REGULATORY MECHANISM; TUMOR GROWTH; UBIQUITINATION; AMINO ACID SEQUENCE; CELL FREE SYSTEM; CHEMISTRY; ISOLATION AND PURIFICATION; METABOLISM; NEOPLASM; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CELL-FREE SYSTEM; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASMS; NF-KAPPA B P50 SUBUNIT; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84927154859     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.03.001     Document Type: Article

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