Effects of ALDH2 genotype, PPI treatment and L-Cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Maejima, Ryuhei ^a   Iijima, Katsunori ^a   Kaihovaara, Pertti ^b   Hatta, Waku ^a   Koike, Tomoyuki ^a   Imatani, Akira ^a   Shimosegawa, Tooru ^a   Salaspuro, Mikko ^b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; CYSTEINE; RABEPRAZOLE; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, HUMAN; CARCINOGEN; PROTON PUMP INHIBITOR;

ACHLORHYDRIA; ADULT; ALCOHOL CONSUMPTION; ALCOHOL OXIDATION; ALCOHOLIC BEVERAGE; ARTICLE; BACTERIAL COLONIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DAIRY PRODUCT; ENZYME ACTIVITY; ENZYME REGULATION; EVENING DOSAGE; FERMENTATION; FIRST PASS EFFECT; FOOD COMPOSITION; GASTRIC SUCTION; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MORNING DOSAGE; MOUTH FLORA; NORMAL HUMAN; PROTEIN EXPRESSION; SALIVA; STOMACH JUICE; STOMACH MUCOSA; STOMACH PH; VOLUNTEER; DRINKING BEHAVIOR; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; PH;

ACETALDEHYDE; ADULT; ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; CARCINOGENS; CYSTEINE; ETHANOL; GASTRIC JUICE; GASTRIC MUCOSA; GENOTYPE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; PROTON PUMP INHIBITORS; SALIVA;

EID: 84927154841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120397     Document Type: Article

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