Acetaldehyde production from ethanol by oral streptococci

Oral Oncology

Volumn 43, Issue 2, 2007, Pages 181-186

  Kurkivuori, Johanna ^a,b   Salaspuro, Ville ^a   Kaihovaara, Pertti ^a   Kari, Kirsti ^b   Rautemaa, Riina ^a,c   Grönroos, Lisa ^a,b   Meurman, Jukka H ^a,b   Salaspuro, Mikko ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Acetaldehyde; ADH enzyme; Carcinogenesis; Ethanol; Oral cancer; Viridans streptococci

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE;

ALPHA HEMOLYTIC STREPTOCOCCUS; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CARCINOGENESIS; CONCENTRATION (PARAMETERS); DIGESTIVE SYSTEM CANCER; ENZYME ACTIVITY; GAS CHROMATOGRAPHY; METABOLITE; MOUTH CANCER; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SENSITIVITY ANALYSIS; SPECTROSCOPY; STRAIN DIFFERENCE; STREPTOCOCCUS MITIS; STREPTOCOCCUS SALIVARIUS; UPPER GASTROINTESTINAL TRACT;

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HUMANS; MOUTH; VIRIDANS STREPTOCOCCI;

EID: 33846563455     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2006.02.005     Document Type: Article

References (31)

1. La Vecchia C., Tavani A., Franceschi S., Levi F., Corrao G., and Negri E. Epidemiology and prevention of oral cancer. Oral Oncol 33 (1997) 302-312
2. Pöschl G., and Seitz H.K. Alcohol and cancer. Alcohol Alcoholism 39 (2004) 155-165
3. Homann N., Jousimies-Somer H., Jokelainen K., Heine R., and Salaspuro M. High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications. Carcinogenesis 18 (1997) 1739-1743
4. 2-propanodeoxyguanosine adducts from acetaldehyde. Nucleic Acids Res 33 (2005) 3513-3520
5. Salaspuro M.P. Acetaldehyde, microbes, and cancer of the digestive tract. Crit Rev Clin Lab Sci 40 (2003) 183-208
6. Salaspuro V., and Salaspuro M. Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva. Int J Cancer 111 (2004) 480-483
7. Homann N., Tillonen J., Meurman J.H., Rintamaki H., Lindqvist C., Rautio M., et al. Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis 21 (2000) 663-668
8. Jokelainen K., Matysiak-Budnik T., Mäkisalo H., Hockerstedt K., and Salaspuro M. High intracolonic acetaldehyde values produced by a bacteriocolonic pathway for ethanol oxidation in piglets. Gut 39 (1996) 100-104
9. Väkeväinen S., Tillonen J., Blom M., Jousimies-Somer H., and Salaspuro M. Acetaldehyde production and other ADH-related characteristics of aerobic bacteria isolated from hypochlorhydric human stomach. Alcohol Clin Exp Res 25 (2001) 421-426
10. Muto M., Hitomi Y., Ohtsu A., Shimada H., Kashiwase Y., Sasaki H., et al. Acetaldehyde production by non-pathogenic Neisseria in human oral microflora: implications for carcinogenesis in upper aerodigestive tract. Int J Cancer 88 (2000) 342-350
11. Tillonen J., Homann N., Rautio M., Jousimies-Somer H., and Salaspuro M. Role of yeasts in the salivary acetaldehyde production from ethanol among risk groups for ethanol-associated oral cavity cancer. Alcohol Clin Exp Res 23 (1999) 1409-1415
12. World Health Organisation. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Int Agency Res Cancer [Lyon, France] 36 (1985) 101-132
13. World Health Organisation. IARC monographs on the evaluation of carcinogenic risks to humans. Int Agency Res Cancer [Lyon, France] 44 (1988) 115
14. Salaspuro V., Hietala J., Kaihovaara P., Pihlajarinne L., Marvola M., and Salaspuro M. Removal of acetaldehyde from saliva by a slow-release buccal tablet of l-cysteine. Int J Cancer 97 (2002) 361-364
15. Jenkinson H.F., and Lamont R.J. Oral microbial communities in sickness and in health. Trends Microbiol 13 (2005) 589-595
16. Marsh P., and Martin M.V. The resident oral microflora. Oral Microbiol 3 (2005) 17-33
17. Jokelainen K., Roine R.P., Väänänen H., Färkkilä M., and Salaspuro M. In vitro acetaldehyde formation by human colonic bacteria. Gut 35 (1994) 1271-1274
18. Holbrook J.J., Yates D.W., Reynolds S.J., Evans R.W., Greenwood C., and Gore M.G. Protein fluorescence of nicotinamide nucleotide-dependent dehydrogenases. Biochem J 128 (1972) 933-940
19. Nosova T., Jokelainen K., Kaihovaara P., Heine R., Jousimies-Somer H., and Salaspuro M. Characteristics of aldehyde dehydrogenases of certain aerobic bacteria representing human colonic flora. Alcohol Alcoholism 33 (1998) 273-280
20. Jokelainen K., Siitonen A., Jousimies-Somer H., Nosova T., Heine R., and Salaspuro M. In vitro alcohol dehydrogenase-mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man. Alcohol Clin Exp Res 20 (1996) 967-972
21. Nosova T., Jousimies-Somer H., Jokelainen K., Heine R., and Salaspuro M. Acetaldehyde production and metabolism by human indigenous and probiotic Lactobacillus and Bifidobacterium strains. Alcohol Alcoholism 35 (2000) 561-568
22. Homann N., Tillonen J., Rintamäki H., Salaspuro M., Lindqvist C., and Meurman J.H. Poor dental status increases acetaldehyde production from ethanol in saliva: a possible link to increased oral cancer risk among heavy drinkers. Oral Oncol 37 (2001) 153-158
23. Nagy K.N., Sonkodi I., Szoke I., Nagy E., and Newman H.N. The microflora associated with human oral carcinomas. Oral Oncol 34 (1998) 304-308
24. Obe G., Jonas R., and Schmidt S. Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: acetaldehyde not ethanol is mutagenic. Mutat Res 174 (1986) 47-51
25. Dellarco V.L. A mutagenicity assessment of acetaldehyde. Mutat Res 195 (1988) 1-20
26. Woutersen R.A., Appelman L.M., Van Garderen-Hoetmer A., and Feron V.J. Inhalation toxicity of acetaldehyde in rats. III. Carcinogenicity study. Toxicology 41 (1986) 213-231
27. Väkeväinen S., Tillonen J., Agarwal D.P., Srivastava N., and Salaspuro M. High salivary acetaldehyde after a moderate dose of alcohol in ALDH2-deficient subjects: strong evidence for the local carcinogenic action of acetaldehyde. Alcohol Clin Exp Res 24 (2000) 873-877
28. Yokoyama A., Muramatsu T., Ohmori T., Yokoyama T., Okuyama K., Takahashi H., et al. Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis 19 (1998) 1383-1387
29. Gubala W., and Zuba D. Saliva as an alternative specimen for alcohol determination in the human body. Pol J Pharmacol 54 (2002) 161-165
30. Ruoff K.L., Whiley R.A., and Beighton D. Streptococcus. Manual Clin Microbiol 1 (2003) 405-417
31. Tillonen J., Kaihovaara P., Jousimies-Somer H., Heine R., and Salaspuro M. Role of catalase in in vitro acetaldehyde formation by human colonic contents. Alcohol Clin Exp Res 22 (1998) 1113-1119