메뉴 건너뛰기




Volumn 12, Issue 1, 2015, Pages 851-864

Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor i receptor and vascular endothelial growth factor-A: Prognostic and predictive markers in triple-negative and non-triple-negative breast cancer

Author keywords

Insulin growth factor insulin growth factor receptor I; Prognosis; Transforming growth factor ; Triple negative breast cancer; Vascular endothelial growth factor

Indexed keywords

ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; CYCLOPHOSPHAMIDE; DOCETAXEL; EPIRUBICIN; FLUOROURACIL; PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN A; ANTINEOPLASTIC AGENT; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MARKER; VEGFA PROTEIN, HUMAN;

EID: 84926683609     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3560     Document Type: Article
Times cited : (51)

References (59)
  • 1
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R, Ward E, Brawley O and Jemal A: Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61: 212-236, 2011.
    • (2011) CA Cancer J Clin , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 2
    • 79954575067 scopus 로고    scopus 로고
    • High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy
    • Litzenburger BC, Creighton CJ, Tsimelzon A, et al: High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res 17: 2314-2327, 2011.
    • (2011) Clin Cancer Res , vol.17 , pp. 2314-2327
    • Litzenburger, B.C.1    Creighton, C.J.2    Tsimelzon, A.3
  • 3
    • 45149094267 scopus 로고    scopus 로고
    • Basal-like breast cancer: A critical review
    • Rakha EA, Reis-Filho JS and Ellis IO: Basal-like breast cancer: a critical review. J Clin Oncol 26: 2568-2581, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 2568-2581
    • Rakha, E.A.1    Reis-Filho, J.S.2    Ellis, I.O.3
  • 6
    • 84866990604 scopus 로고    scopus 로고
    • Update on triple-negative breast cancer: Prognosis and management strategies
    • Brouckaert O, Wildiers H, Floris G and Neven P: Update on triple-negative breast cancer: prognosis and management strategies. Int J Womens Health 4, 511-520, 2012
    • (2012) Int J Womens Health , vol.4 , pp. 511-520
    • Brouckaert, O.1    Wildiers, H.2    Floris, G.3    Neven, P.4
  • 8
    • 80054858200 scopus 로고    scopus 로고
    • Adjuvant systemic treatment for individual patients with triple negative breast cancer
    • Oakman C, Moretti E, Galardi F, Biagioni C, Santarpia L, Biganzoli L and Di Leo A: Adjuvant systemic treatment for individual patients with triple negative breast cancer. Breast 20 (Suppl 3): S135-S141, 2011.
    • (2011) Breast , vol.20 , pp. S135-S141
    • Oakman, C.1    Moretti, E.2    Galardi, F.3    Biagioni, C.4    Santarpia, L.5    Biganzoli, L.6    Di Leo, A.7
  • 10
    • 0037474223 scopus 로고    scopus 로고
    • Autocrine transforming growth factor-beta signaling mediates Smad-independent motility in human cancer cells
    • Dumont N, Bakin AV and Arteaga CL: Autocrine transforming growth factor-beta signaling mediates Smad-independent motility in human cancer cells. J Biol Chem 278: 3275-3285, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 3275-3285
    • Dumont, N.1    Bakin, A.V.2    Arteaga, C.L.3
  • 11
    • 67349091089 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling: Emerging stem cell target in metastatic breast cancer?
    • Tan AR, Alexe G and Reiss M: Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer? Breast Cancer Res Treat 115: 453-495, 2009.
    • (2009) Breast Cancer Res Treat , vol.115 , pp. 453-495
    • Tan, A.R.1    Alexe, G.2    Reiss, M.3
  • 12
    • 0034212632 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) in breast cancer: Comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen
    • Adams J, Carder PJ, Downey S, Forbes MA, MacLennan K, Allgar V, Kaufman S, Hallam S, Bicknell R, Walker JJ, et al: Vascular endothelial growth factor (VEGF) in breast cancer: comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen. Cancer Res 60: 2898-2905, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2898-2905
    • Adams, J.1    Carder, P.J.2    Downey, S.3    Forbes, M.A.4    Maclennan, K.5    Allgar, V.6    Kaufman, S.7    Hallam, S.8    Bicknell, R.9    Walker, J.J.10
  • 13
    • 0033875585 scopus 로고    scopus 로고
    • Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: Clinical evidence of platelet scavenging?
    • George ML, Eccles SA, Tutton MG, Abulafi AM and Swift RI: Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: clinical evidence of platelet scavenging? Clin Cancer Res 6: 3147-3152, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 3147-3152
    • George, M.L.1    Eccles, S.A.2    Tutton, M.G.3    Abulafi, A.M.4    Swift, R.I.5
  • 15
    • 46749109263 scopus 로고    scopus 로고
    • Circulating levels of sex steroids and prolactin in premenopausal women and risk of breast cancer
    • Hankinson SE: Circulating levels of sex steroids and prolactin in premenopausal women and risk of breast cancer. Adv Exp Med Biol 617: 161-169, 2008.
    • (2008) Adv Exp Med Biol , vol.617 , pp. 161-169
    • Hankinson, S.E.1
  • 18
    • 0029960090 scopus 로고    scopus 로고
    • Varying patterns of expression of insulin-like growth factors i and II and their receptors in murine mammary adenocarcinomas of different metastasizing ability
    • Guerra FK, Eijan AM, Puricelli L, Alonso DF, Bal de Kier Joffé E, Kornblihgtt AR, Charreau EH and Elizalde PV: Varying patterns of expression of insulin-like growth factors I and II and their receptors in murine mammary adenocarcinomas of different metastasizing ability. Int J Cancer 65: 812-820, 1996.
    • (1996) Int J Cancer , vol.65 , pp. 812-820
    • Guerra, F.K.1    Eijan, A.M.2    Puricelli, L.3    Alonso, D.F.4    Bal De Kier Joffé, E.5    Kornblihgtt, A.R.6    Charreau, E.H.7    Elizalde, P.V.8
  • 20
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors European organization for research and treatment of cancer, national cancer institute of the united states, national cancer institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al: New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92: 205-216, 2000.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 22
    • 0035800526 scopus 로고    scopus 로고
    • CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation
    • Jones C, Nonni AV, Fulford L, Merrett S, Chaggar R, Eusebi V and Lakhani SR: CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation. Br J Cancer 85: 422-427, 2001.
    • (2001) Br J Cancer , vol.85 , pp. 422-427
    • Jones, C.1    Nonni, A.V.2    Fulford, L.3    Merrett, S.4    Chaggar, R.5    Eusebi, V.6    Lakhani, S.R.7
  • 24
    • 44049093342 scopus 로고    scopus 로고
    • Increased expression of osteopontin in patients with triple-negative breast cancer
    • Wang X, Chao L, Ma G, Chen L, Tian B, Zang Y and Sun J: Increased expression of osteopontin in patients with triple-negative breast cancer. Eur J Clin Invest 38: 438-446, 2008.
    • (2008) Eur J Clin Invest , vol.38 , pp. 438-446
    • Wang, X.1    Chao, L.2    Ma, G.3    Chen, L.4    Tian, B.5    Zang, Y.6    Sun, J.7
  • 25
    • 0034911060 scopus 로고    scopus 로고
    • Serum levels of transforming growth factor beta1 in patients with breast cancer
    • Sheen-Chen SM, Chen HS, Sheen CW, Eng HL and Chen WJ: Serum levels of transforming growth factor beta1 in patients with breast cancer. Arch Surg 136, 937-940, 2001.
    • (2001) Arch Surg , vol.136 , pp. 937-940
    • Sheen-Chen, S.M.1    Chen, H.S.2    Sheen, C.W.3    Eng, H.L.4    Chen, W.J.5
  • 27
    • 0033377548 scopus 로고    scopus 로고
    • TGF-beta and cancer
    • Reiss M: TGF-beta and cancer. Microbes Infect 1: 1327-1347, 1999.
    • (1999) Microbes Infect , vol.1 , pp. 1327-1347
    • Reiss, M.1
  • 29
    • 0036291016 scopus 로고    scopus 로고
    • Antiestrogenic regulation of transforming growth factor beta receptors i and II in human breast cancer cells
    • Buck M, von der Fecht J and Knabbe C: Antiestrogenic regulation of transforming growth factor beta receptors I and II in human breast cancer cells. Ann NY Acad Sci 963, 140-143, 2002.
    • (2002) Ann NY Acad Sci , vol.963 , pp. 140-143
    • Buck, M.1    Von Der Fecht, J.2    Knabbe, C.3
  • 32
    • 0242285692 scopus 로고    scopus 로고
    • TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression
    • Tang B, Vu M, Booker T, Santner SJ, Miller FR, Anver MR and Wakefield LM: TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. J Clin Invest 112: 1116-1124, 2003.
    • (2003) J Clin Invest , vol.112 , pp. 1116-1124
    • Tang, B.1    Vu, M.2    Booker, T.3    Santner, S.J.4    Miller, F.R.5    Anver, M.R.6    Wakefield, L.M.7
  • 34
    • 67349107824 scopus 로고    scopus 로고
    • Transforming growth factor-b signaling strength determines target gene expression profile in human keratinocytes
    • Kareddula A, Zachariah E, Notterman D and Reiss M: Transforming growth factor-b signaling strength determines target gene expression profile in human keratinocytes. J Epithel Biol Pharmaco 1, 40-94, 2008.
    • (2008) J Epithel Biol Pharmaco , vol.1 , pp. 40-94
    • Kareddula, A.1    Zachariah, E.2    Notterman, D.3    Reiss, M.4
  • 35
    • 0030659077 scopus 로고    scopus 로고
    • Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma
    • Marrogi AJ, Munshi A, Merogi AJ, Ohadike Y, El-Habashi A, Marrogi OL and Freeman SM: Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma. Int J Cancer 74: 492-501, 1997.
    • (1997) Int J Cancer , vol.74 , pp. 492-501
    • Marrogi, A.J.1    Munshi, A.2    Merogi, A.J.3    Ohadike, Y.4    El-Habashi, A.5    Marrogi, O.L.6    Freeman, S.M.7
  • 36
    • 0027053058 scopus 로고
    • Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer
    • Gorsch SM, Memoli VA, Stukel TA, Gold LI and Arrick BA: Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer. Cancer Res 52: 6949-6952, 1992.
    • (1992) Cancer Res , vol.52 , pp. 6949-6952
    • Gorsch, S.M.1    Memoli, V.A.2    Stukel, T.A.3    Gold, L.I.4    Arrick, B.A.5
  • 37
    • 31444442248 scopus 로고    scopus 로고
    • Determination of TGFbeta1 protein level in human primary breast cancers and its relationship with survival
    • Desruisseau S, Palmari J, Giusti C, Romain S, Martin PM and Berthois Y: Determination of TGFbeta1 protein level in human primary breast cancers and its relationship with survival. Br J Cancer 94: 239-246, 2006.
    • (2006) Br J Cancer , vol.94 , pp. 239-246
    • Desruisseau, S.1    Palmari, J.2    Giusti, C.3    Romain, S.4    Martin, P.M.5    Berthois, Y.6
  • 38
    • 84863898644 scopus 로고    scopus 로고
    • Prognostic utility of circulating transforming growth factor beta 1 in breast cancer patients
    • Dave H, Shah M, Trivedi S and Shukla S: Prognostic utility of circulating transforming growth factor beta 1 in breast cancer patients. Int J Biol Markers 27: 53-59, 2012.
    • (2012) Int J Biol Markers , vol.27 , pp. 53-59
    • Dave, H.1    Shah, M.2    Trivedi, S.3    Shukla, S.4
  • 39
    • 69249212216 scopus 로고    scopus 로고
    • Prognostic value of serum vascular endothelial growth factor in Egyptian females with metastatic triple negative breast cancer
    • Taha FM, Zeeneldin AA, Helal AM, Gaber AA, Sallam YA, Ramadan H and Moneer MM: Prognostic value of serum vascular endothelial growth factor in Egyptian females with metastatic triple negative breast cancer. Clin Biochem 42: 1420-1426, 2009.
    • (2009) Clin Biochem , vol.42 , pp. 1420-1426
    • Taha, F.M.1    Zeeneldin, A.A.2    Helal, A.M.3    Gaber, A.A.4    Sallam, Y.A.5    Ramadan, H.6    Moneer, M.M.7
  • 40
    • 0037386821 scopus 로고    scopus 로고
    • Combined vascular endothelial growth factor and TP53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer
    • Berns EM, Klijn JG, Look MP, et al: Combined vascular endothelial growth factor and TP53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer. Clin Cancer Res 9: 1253-1258, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 1253-1258
    • Berns, E.M.1    Klijn, J.G.2    Look, M.P.3
  • 42
    • 77149173177 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Role of antiangiogenic agents
    • Greenberg S and Rugo HS: Triple-negative breast cancer: role of antiangiogenic agents. Cancer J 16: 33-38, 2010.
    • (2010) Cancer J , vol.16 , pp. 33-38
    • Greenberg, S.1    Rugo, H.S.2
  • 43
    • 27344431724 scopus 로고    scopus 로고
    • Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo
    • Björndahl M, Cao R, Nissen LJ, et al: Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo. Proc Natl Acad Sci USA 102: 15593-15598, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15593-15598
    • Björndahl, M.1    Cao, R.2    Nissen, L.J.3
  • 44
    • 0036970842 scopus 로고    scopus 로고
    • The role of the IGF system in cancer: From basic to clinical studies and clinical applications
    • Moschos SJ and Mantzoros CS: The role of the IGF system in cancer: from basic to clinical studies and clinical applications. Oncology 63: 317-332, 2002.
    • (2002) Oncology , vol.63 , pp. 317-332
    • Moschos, S.J.1    Mantzoros, C.S.2
  • 45
    • 0029119731 scopus 로고
    • Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity
    • Rubin R and Baserga R: Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity. Lab Invest 73: 311-331, 1995.
    • (1995) Lab Invest , vol.73 , pp. 311-331
    • Rubin, R.1    Baserga, R.2
  • 46
    • 0030727705 scopus 로고    scopus 로고
    • Dietary restriction reduces insulin-like growth factor i levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice
    • Dunn SE, Kari FW, French J, Leininger JR, Travlos G, Wilson R and Barrett JC: Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res 57: 4667-4672, 1997.
    • (1997) Cancer Res , vol.57 , pp. 4667-4672
    • Dunn, S.E.1    Kari, F.W.2    French, J.3    Leininger, J.R.4    Travlos, G.5    Wilson, R.6    Barrett, J.C.7
  • 47
    • 0032850369 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death-proliferative and anti-apoptotic effects
    • Gooch JL, Van Den Berg CL and Yee D: Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death-proliferative and anti-apoptotic effects. Breast Cancer Res Treat 56: 1-10, 1999.
    • (1999) Breast Cancer Res Treat , vol.56 , pp. 1-10
    • Gooch, J.L.1    Van Den Berg, C.L.2    Yee, D.3
  • 48
    • 10744228790 scopus 로고    scopus 로고
    • Relationships between plasma insulin-like growth factor-I and insulin-like growth factor binding protein-3 and second breast cancer risk in a prevention trial of fenretinide
    • Decensi A, Veronesi U, Miceli R, Johansson H, Mariani L, Camerini T, Di Mauro MG, Cavadini E, De Palo G, Costa A, et al: Relationships between plasma insulin-like growth factor-I and insulin-like growth factor binding protein-3 and second breast cancer risk in a prevention trial of fenretinide. Clin Cancer Res 9: 4722-4729, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 4722-4729
    • Decensi, A.1    Veronesi, U.2    Miceli, R.3    Johansson, H.4    Mariani, L.5    Camerini, T.6    Di Mauro, M.G.7    Cavadini, E.8    De Palo, G.9    Costa, A.10
  • 50
    • 0035036735 scopus 로고    scopus 로고
    • Estrogen suppression of EGFR expression in breast cancer cells: A possible mechanism to modulate growth
    • Yarden RI, Wilson MA and Chrysogelos SA: Estrogen suppression of EGFR expression in breast cancer cells: a possible mechanism to modulate growth. J Cell Biochem 81 (Suppl 36): 232-246, 2001.
    • (2001) J Cell Biochem , vol.81 , pp. 232-246
    • Yarden, R.I.1    Wilson, M.A.2    Chrysogelos, S.A.3
  • 52
    • 34548013092 scopus 로고    scopus 로고
    • Expression patterns of insulin-like growth factor 1 (IGF-I) and its receptor in mammary tissues and their associations with breast cancer survival
    • Shin A, Ren Z, Shu XO, Cai Q, Gao YT and Zheng W: Expression patterns of insulin-like growth factor 1 (IGF-I) and its receptor in mammary tissues and their associations with breast cancer survival. Breast Cancer Res Treat 105: 55-61, 2007.
    • (2007) Breast Cancer Res Treat , vol.105 , pp. 55-61
    • Shin, A.1    Ren, Z.2    Shu, X.O.3    Cai, Q.4    Gao, Y.T.5    Zheng, W.6
  • 53
  • 54
    • 33745211914 scopus 로고    scopus 로고
    • Transcriptional regulation of the insulin-like growth factor-I receptor gene in breast cancer
    • Sarfstein R, Maor S, Reizner N, Abramovitch S and Werner H: Transcriptional regulation of the insulin-like growth factor-I receptor gene in breast cancer. Mol Cell Endocrinol 252: 241-246, 2006.
    • (2006) Mol Cell Endocrinol , vol.252 , pp. 241-246
    • Sarfstein, R.1    Maor, S.2    Reizner, N.3    Abramovitch, S.4    Werner, H.5
  • 55
    • 0033617446 scopus 로고    scopus 로고
    • Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways
    • Valentinis B, Romano G, Peruzzi F, Morrione A, Prisco M, Soddu S, Cristofanelli B, Sacchi A and Baserga R: Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways. J Biol Chem 274: 12423-12430, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 12423-12430
    • Valentinis, B.1    Romano, G.2    Peruzzi, F.3    Morrione, A.4    Prisco, M.5    Soddu, S.6    Cristofanelli, B.7    Sacchi, A.8    Baserga, R.9
  • 56
    • 79958292200 scopus 로고    scopus 로고
    • Promising molecular targeted therapies in breast cancer
    • Munagala R, Aqil F and Gupta RC: Promising molecular targeted therapies in breast cancer. Indian J Pharmacol 43: 236-245, 2011.
    • (2011) Indian J Pharmacol , vol.43 , pp. 236-245
    • Munagala, R.1    Aqil, F.2    Gupta, R.C.3
  • 58
    • 84873887977 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor i (IGF-IR) and vascular endothelial growth factor receptor 2 (VEGFR-2) are expressed on the circulating epithelial tumor cells of breast cancer patients
    • Pizon M, Zimon DS, Pachmann U and Pachmann K: Insulin-like growth factor receptor I (IGF-IR) and vascular endothelial growth factor receptor 2 (VEGFR-2) are expressed on the circulating epithelial tumor cells of breast cancer patients. PLoS One 8: e56836, 2013.
    • (2013) PLoS One , vol.8 , pp. e56836
    • Pizon, M.1    Zimon, D.S.2    Pachmann, U.3    Pachmann, K.4
  • 59
    • 53949118953 scopus 로고    scopus 로고
    • Circulating transforming growth factor-beta-1 and breast cancer prognosis: Results from the Shanghai Breast Cancer Study
    • Grau AM, Wen W, Ramroopsingh DS, Gao YT, Zi J, Cai Q, Shu XO and Zheng W: Circulating transforming growth factor-beta-1 and breast cancer prognosis: results from the Shanghai Breast Cancer Study. Breast Cancer Res Treat 112: 335-341, 2008.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 335-341
    • Grau, A.M.1    Wen, W.2    Ramroopsingh, D.S.3    Gao, Y.T.4    Zi, J.5    Cai, Q.6    Shu, X.O.7    Zheng, W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.