Persister cells in biofilm associated infections

Advances in Experimental Medicine and Biology

Volumn 831, Issue , 2015, Pages 1-9

  Conlon, Brian P ^a   Rowe, Sarah E ^a   Lewis, Kim ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CHLORHEXIDINE; CIPROFLOXACIN; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; OFLOXACIN; RIFAMPICIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ARTICLE; BIOFILM; CANDIDA ALBICANS; CELLS; CYSTIC FIBROSIS; DRUG TOLERANCE; ESCHERICHIA COLI; GENE; GENE DELETION; GENE SWITCHING; GLPD GENE; HIPA GENE; HUMAN; INFECTION; NONHUMAN; PERSISTER CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS MUTANS; TKTA GENE; BACTERIAL INFECTIONS; BIOLOGICAL MODEL; CANDIDIASIS; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; MICROBIAL CONSORTIUM; MICROBIOLOGY; MULTIDRUG RESISTANCE; PHYSIOLOGY;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BIOFILMS; CANDIDIASIS; DRUG RESISTANCE, MULTIPLE; HUMANS; MICROBIAL CONSORTIA; MODELS, BIOLOGICAL;

EID: 84926675003     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-09782-4_1     Document Type: Article

References (58)

1. Allison KR, Brynildsen MP, Collins JJ (2011) Metaboliteenabled eradication of bacterial persisters by aminoglycosides. Nature 473: 216
2. Amato SM, Brynildsen MP (2014) Nutrient transitions are a source of persisters in Escherichia coli biofilms. PLo S One 9: e93110
3. Amato SM et al (2014) The role of metabolism in bacterial persistence. Front Microbiol 5: 70
4. Ammons MC (2010) Anti-biofilm strategies and the need for innovations in wound care. Recent Pat Antiinfect Drug Discov 5: 10
5. Anderl JN, Franklin MJ, Stewart PS (2000) Role of antibiotic penetration limitation in Klebsiella pneumonia biofilm resistance to ampicillin and ciprofloxacin. Antimicrob Agents Chemother 44: 1818
6. Baba T et al (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2: 2006. 0008
7. Balaban NQ, Merrin J, Chait R, Kowalik L, Leibler S (2004) Bacterial persistence as a phenotypic switch. Science 305: 1622
8. Bernier SP et al (2013) Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin. PLo S Genet 9: e1003144
9. Bigger JW (1944) Treatment of staphylococcal infections with penicillin. Lancet ii: 497
10. Brotz-Oesterhelt H et al (2005) Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nat Med 11: 1082
11. Conlon BP et al (2013) Activated Clp P kills persisters and eradicates a chronic biofilm infection. Nature 503: 365
12. Costerton JW et al (1987) Bacterial biofilms in nature and disease. Annu Rev Microbiol 41: 435
13. Darouiche RO et al (1994) Vancomycin penetration into biofilm covering infected prostheses and effect on bacteria. J Infect Dis 170: 720
14. Davis BD (1987) Mechanism of bactericidal action of aminoglycosides. Microbiol Rev 51: 341
15. De Groote VN et al (2009) Novel persistence genes in Pseudomonas aeruginosa identified by high-throughput screening. FEMS Microbiol Lett 297: 73
16. Donegan NP, Cheung AL (2009) Regulation of the maz EF toxin-antitoxin module in Staphylococcus aureus and its impact on sig B expression. J Bacteriol 191: 2795
17. Donegan NP, Thompson ET, Fu Z, Cheung AL (2010) Proteolytic regulation of toxin-antitoxin systems by Clp PC in Staphylococcus aureus. J Bacteriol 192: 1416
18. Dorr T, Vulic M, Lewis K (2010) Ciprofloxacin causes persister formation by inducing the Tis B toxin in Escherichia coli. PLo S Biol 8: e1000317
19. Drlica K, Zhao X (1997) DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev 61: 377
20. Durfee T, Hansen AM, Zhi H, Blattner FR, Jin DJ (2008) Transcription profiling of the stringent response in Escherichia coli. J Bacteriol 190: 1084
21. Falla TJ, Chopra I (1998) Joint tolerance to beta-lactam and fluoroquinolone antibiotics in Escherichia coli results from overexpression of hip A. Antimicrob Agents Chemother 42: 3282
22. Farrell CM, Grossman AD, Sauer RT (2005) Cytoplasmic degradation of ssr A-tagged proteins. Mol Microbiol 57: 1750
23. Gerdes K, Christensen SK, Lobner-Olesen A (2005) Prokaryotic toxin-antitoxin stress response loci. Nat Rev Microbiol 3: 371
24. Germain E, Castro-Roa D, Zenkin N, Gerdes K (2013) Molecular mechanism of bacterial persistence by Hip A. Mol Cell 52: 248
25. Girgis HS, Harris K, Tavazoie S (2012) Large mutational target size for rapid emergence of bacterial persistence. Proc Natl Acad Sci U S A 109: 12740
26. Gristina AG, Hobgood CD, Webb LX, Myrvik QN (1987) Adhesive colonization of biomaterials and antibiotic resistance. Biomaterials 8: 423
27. Hansen S, Lewis K, Vulić M (2008) The role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. Antimicrob Agents Chemother 52: 2718-2726
28. Hansen S et al (2012) Regulation of the Escherichia coli Hip BA toxin-antitoxin system by proteolysis. PLo S One 7: e39185
29. Hayes F, Van Melderen L (2011) Toxins-antitoxins: diversity, evolution and function. Crit Rev Biochem Mol Biol 46: 386
30. Helaine S et al (2014) Internalization of Salmonella by macrophages induces formation of nonreplicating persisters. Science 343: 204
31. Jefferson KK, Goldmann DA, Pier GB (2005) Use of confocal microscopy to analyze the rate of vancomycin penetration through Staphylococcus aureus biofilms. Antimicrob Agents Chemother 49: 2467
32. Johnson PJ, Levin BR (2013) Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus. PLo S Genet 9: e1003123
33. Kaspy I et al (2013) Hip A-mediated antibiotic persistence via phosphorylation of the glutamyl-t RNA-synthetase. Nat Commun 4: 3001
34. Keren I, Kaldalu N, Spoering A, Wang Y, Lewis K (2004) Persister cells and tolerance to antimicrobials. FEMS Microbiol Lett 230: 13
35. Keren I, Mulcahy LR, Lewis K (2012) Persister eradication: lessons from the world of natural products. Methods Enzymol 517: 387
36. Kim Y, Wood TK (2010) Toxins Hha and Csp D and small RNA regulator Hfq are involved in persister cell formation through Mqs R in Escherichia coli. Biochem Biophys Res Commun 391: 209
37. Kim JS et al (2011) Selective killing of bacterial persisters by a single chemical compound without affecting normal antibiotic-sensitive cells. Antimicrob Agents Chemother 55: 5380
38. Kirstein J et al (2009) The antibiotic ADEP reprogrammes Clp P, switching it from a regulated to an uncontrolled protease. EMBO Mol Med 1: 37
39. Lafleur MD, Qi Q, Lewis K (2010) Patients with long-term oral carriage harbor high-persister mutants of Candida albicans. Antimicrob Agents Chemother 54: 39
40. Lebeaux D et al. (2014) p H-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms. J Infect Dis. doi 10. 1093/infdis/jiu286
41. Leung V, Levesque CM (2012) A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance. J Bacteriol 194: 2265
42. Lewis K (2001) Riddle of biofilm resistance. Antimicrob Agents Chemother 45: 999
43. Maisonneuve E, Shakespeare LJ, Jorgensen MG, Gerdes K (2011) Bacterial persistence by RNA endonucleases. Proc Natl Acad Sci U S A 108: 13206
44. Maisonneuve E, Castro-Camargo M, Gerdes K (2013) (p)pp Gpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity. Cell 154: 1140
45. Michel A et al (2006) Global regulatory impact of Clp P protease of Staphylococcus aureus on regulons involved in virulence, oxidative stress response, autolysis, and DNA repair. J Bacteriol 188: 5783
46. Moker N, Dean CR, Tao J (2010) Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum-sensing signaling molecules. J Bacteriol 192: 1946
47. Moyed HS, Bertrand KP (1983) hip A, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J Bacteriol 155: 768
48. Mulcahy LR, Burns JL, Lory S, Lewis K (2010) Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis. J Bacteriol 192: 6191
49. Murakami K et al (2005) Role for rpo S gene of Pseudomonas aeruginosa in antibiotic tolerance. FEMS Microbiol Lett 242: 161
50. Nguyen D et al (2011) Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science 334: 982
51. Norton JP, Mulvey MA (2012) Toxin-antitoxin systems are important for niche-specific colonization and stress resistance of uropathogenic Escherichia coli. PLo S Pathog 8: e1002954
52. Ogura T, Hiraga S (1983) Mini-F plasmid genes that couple host cell division to plasmid proliferation. Proc Natl Acad Sci U S A 80: 4784
53. Spoering AL, Vulic M, Lewis K (2006) Glp D and Pls B participate in persister cell formation in Escherichia coli. J Bacteriol 188: 5136
54. Tipper DJ, Strominger JL (1965) Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine. Proc Natl Acad Sci U S A 54: 1133
55. Tsilibaris V, Maenhaut-Michel G, Van Melderen L (2006) Biological roles of the Lon ATP-dependent protease. Res Microbiol 157: 701
56. Viducic D et al (2006) Functional analysis of spo T, rel A and dks A genes on quinolone tolerance in Pseudomonas aeruginosa under nongrowing condition. Microbiol Immunol 50: 349
57. Vrany JD, Stewart PS, Suci PA (1997) Comparison of recalcitrance to ciprofloxacin and levofloxacin exhibited by Pseudomonas aeruginosa biofilms displaying rapid-transport characteristics. Antimicrob Agents Chemother 41: 1352
58. Zhou YN, Jin DJ (1998) The rpo B mutants destabilizing initiation complexes at stringently controlled promoters behave like "stringent" RNA polymerases in Escherichia coli. Proc Natl Acad Sci U S A 95: 2908