Large mutational target size for rapid emergence of bacterial persistence

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 31, 2012, Pages 12740-12745

  Girgis, Hany S ^a,b   Harris, Kendra ^a,c   Tavazoie, Saeed ^a,d  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Adaptation; Evolution; Genetic interactions; Systems biology

Indexed keywords

AMPICILLIN; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; METHIONINE TRANSFER RNA LIGASE; METHYLGLYOXAL; TRANSKETOLASE; TRANSKETOLASE A; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL METABOLISM; BACTERIAL MUTATION; BACTERIAL SURVIVAL; BACTERIUM MUTANT; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE INSERTION; GENE INTERACTION; GENE MAPPING; GENETIC EPISTASIS; HIPB GENE; METG GENE; MICROARRAY ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; RFAQ GENE; SIGNAL TRANSDUCTION; TRANSPOSON; WILD TYPE; YJBE GENE;

AMPICILLIN; ANTI-BACTERIAL AGENTS; DNA FOOTPRINTING; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84864507798     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1205124109     Document Type: Article

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