MicroRNA-21, induced by high glucose, modulates macrophage apoptosis via programmed cell death 4

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 463-469

  Shang, Yuan Yuan ^a   Fang, Ning Ning ^a   Wang, Feng ^a   Wang, Hui ^a   Wang, Zhi Hao ^a   Tang, Meng Xiong ^a   Peng, Jie ^a   Zhang, Yun ^a   Zhang, Wei ^a   Zhong, Ming ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Atherosclerosis; High glucose; Macrophage; microRNA 21; Programmed cell death 4

Indexed keywords

CASPASE 3; GLUCOSE; MICRORNA 21; APOPTOSIS REGULATORY PROTEIN; MESSENGER RNA; MICRORNA; MIRN21 MICRORNA, MOUSE; PDCD4 PROTEIN, MOUSE; RNA BINDING PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; FLOW CYTOMETRY; MACROPHAGE; NONHUMAN; PROGRAMMED CELL DEATH 4; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ATHEROSCLEROSIS; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ATHEROSCLEROSIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; MACROPHAGES; MICE; MICRORNAS; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84926646131     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3398     Document Type: Article

References (41)

1. Bornfeldt KE and Tabas I: Insulin resistance, hyperglycemia and atherosclerosis. Cell Metab 14: 575-585, 2011.
2. Hurst RT and Lee RW: Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: mechanisms and management. Ann Intern Med 139: 824-834, 2003.
3. Tabas I: Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arterioscler Thromb Vasc Biol 25: 2255-2264, 2005.
4. Kolodgie FD, Narula J, Burke AP, Haider N, Farb A, Hui-Liang Y, Smialek J and Virmani R: Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death. Am J Pathol 157: 1259-1268, 2000.
5. Liang CP, Han S, Senokuchi T and Tall AR: The macrophage at the crossroads of insulin resistance and atherosclerosis. Circ Res 100: 1546-1555, 2007.
6. Burke AP, Kolodgie FD, Zieske A, Fowler DR, Weber DK, Varghese PJ, Farb A and Virmani R: Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study. Arterioscler Thromb Vasc Biol 24: 1266-1271, 2004.
7. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ: miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34: D140-D144, 2006.
8. Zamore PD and Haley B: Ribo-gnome: the big world of small RNAs. Science 309: 1519-1524, 2005.
9. Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, et al: Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet 37: 766-770, 2005.
10. Lewis BP, Burge CB and Bartel DP: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20, 2005.
11. Bartel DP: MicroRNAs: genomics, biogenesis, mechanism and function. Cell 116: 281-297, 2004.
12. Nugent M, Miller N and Kerin MJ: MicroRNAs in colorectal cancer: function, dysregulation and potential as novel biomarkers. Eur J Surg Oncol 7: 649-654, 2011.
13. Hennessy E, Clynes M, Jeppesen PB and O'Driscoll L: Identification of microRNAs with a role in glucose stimulated insulin secretion by expression profiling of MIN6 cells. Biochem Biophys Res Commun 396: 457-462, 2010.
14. Urbich C, Kuehbacher A and Dimmeler S: Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res 79: 581-588, 2008.
15. Han M, Toli J and Abdellatif M: MicroRNAs in the cardiovascular system. Curr Opin Cardiol 26: 181-189, 2011.
16. Folini M, Gandellini P, Longoni N, Profumo V, Callari M, Pennati M, Colecchia M, Supino R, Veneroni S, Salvioni R, et al: miR-21: an oncomir on strike in prostate cancer. Mol Cancer 9: 12, 2010.
17. Cheng Y, Ji R, Yue J, Yang J, Liu X, Chen H, Dean DB and Zhang C: MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol 170: 1831-1840, 2007.
18. Roy S, Khanna S, Hussain SR, Biswas S, Azad A, Rink C, Gnyawali S, Shilo S, Nuovo GJ and Sen CK: MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc Res 82: 21-29, 2009.
19. Cheng Y and Zhang C: MicroRNA-21 in cardiovascular disease. J Cardiovasc Transl Res 3: 251-255, 2010.
20. Weber M, Baker MB, Moore JP and Searles CD: MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity. Biochem Biophys Res Commun 393: 643-648, 2010.
21. Ji R, Cheng Y, Yue J, Yang J, Liu X, Chen H, Dean DB and Zhang C: MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res 100: 1579-1588, 2007.
22. Raitoharju E, Lyytikäinen LP, Levula M, Oksala N, Mennander A, Tarkka M, Klopp N, Illig T, Kähönen M, Karhunen PJ, et al: miR-21, miR-210, miR-34a and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere vascular study. Atherosclerosis 219: 211-217, 2011.
23. Davis BN, Hilyard AC, Lagna G and Hata A: SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454: 56-61, 2008.
24. Cheng Y, Liu X, Zhang S, Lin Y, Yang J and Zhang C: MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. J Mol Cell Cardiol 47: 5-14, 2009.
25. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408, 2001.
26. Selcuklu SD, Donoghue MT and Spillane C: miR-21 as a key regulator of oncogenic processes. Biochem Soc Trans 37: 918-925, 2009.
27. Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W and Tuschl T: Identification of tissue-specific microRNAs from mouse. Curr Biol 12: 735-739, 2002.
28. Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y and O'Neill LA: Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol 11: 141-147, 2010.
29. Lin Y, Liu X, Cheng Y, Yang J, Huo Y and Zhang C: Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J Biol Chem 284: 7903-7913, 2009.
30. Yin C, Wang X and Kukreja RC: Endogenous microRNAs induced by heat-shock reduce myocardial infarction following ischemia-reperfusion in mice. FEBS Lett 582: 4137-4142, 2008.
31. Tatsuguchi M, Seok HY, Callis TE, Thomson JM, Chen JF, Newman M, Rojas M, Hammond SM and Wang DZ: Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol 42: 1137-1141, 2007.
32. Carletti MZ, Fiedler SD and Christenson LK: MicroRNA 21 blocks apoptosis in mouse periovulatory granulosa cells. Biol Reprod 83: 286-295, 2010.
33. Zhou X, Zhang J, Jia Q, Ren Y, Wang Y, Shi L, Liu N, Wang G, Pu P, You Y and Kang C: Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3. Oncol Rep 24: 195-201, 2010.
34. Dong S, Cheng Y, Yang J, Li J, Liu X, Wang X, Wang D, Krall TJ, Delphin ES and Zhang C: MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J Biol Chem 284: 29514-29525, 2009.
35. Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, et al: MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456: 980-984, 2008.
36. Liang JL, Xiao DZ, Liu XY, Lin QX, Shan ZX, Zhu JN, Lin SG and Yu XY: High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase. Clin Exp Pharmacol Physiol 37: 969-973, 2010.
37. Liu X, Cheng Y, Yang J, Krall TJ, Huo Y and Zhang C: An essential role of PDCD4 in vascular smooth muscle cell apoptosis and proliferation: implications for vascular disease. Am J Physiol Cell Physiol 298: C1481-C1488, 2010.
38. Yu Y, Kanwar SS, Patel BB, Oh PS, Nautiyal J, Sarkar FH and Majumdar AP: MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFβR2) in colon cancer cells. Carcinogenesis 33: 68-76, 2012.
39. Gaur AB, Holbeck SL, Colburn NH and Israel MA: Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. Neuro Oncol 13: 580-590, 2011.
40. Cheng Y, Zhu P, Yang J, Liu X, Dong S, Wang X, Chun B, Zhuang J and Zhang C: Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4. Cardiovasc Res 87: 431-439, 2010.
41. Allgayer H: Pdcd4, a colon cancer prognostic that is regulated by a microRNA. Crit Rev Oncol Hematol 73: 185-191, 2010.