Molecular determinants of transport stimulation of EAAT2 are located at interface between the trimerization and substrate transport domains

Journal of Neurochemistry

Volumn 133, Issue 2, 2015, Pages 199-210

  Mortensen, Ole V ^a   Liberato, José L ^b   Coutinho Netto, Joaquim ^b   Dos Santos, Wagner F ^b   Fontana, Andréia C K ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

excitatory amino acid transporter 2 (EAAT2); glutamate transporter; glutamate uptake; Parawixia bistriata; transport enhancement

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER 2; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMIC ACID; HISTIDINE; SERINE; SPIDER VENOM; TOXIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; MUTANT; NEUROTRANSMITTER UPTAKE; PRIORITY JOURNAL; PROTEIN DOMAIN; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; TRANSPORT AT THE CELLULAR LEVEL;

ARANEAE;

ANIMALS; BIOLOGICAL TRANSPORT; CERCOPITHECUS AETHIOPS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMIC ACID; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; SPIDER VENOMS; TOXINS, BIOLOGICAL; TRANSFECTION;

EID: 84926633502     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13047     Document Type: Article

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