The use of cisplatin-loaded mucoadhesive nanofibers for local chemotherapy of cervical cancers in mice

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 93, Issue , 2015, Pages 127-135

  Zong, Shan ^b   Wang, Xue ^b   Yang, Yongping ^b   Wu, Wenbin ^c   Li, Hongjun ^b   Ma, Yue ^b   Lin, Wenhai ^a   Sun, Tingting ^a   Huang, Yubin ^a   Xie, Zhigang ^a   Yue, Ying ^b   Liu, Shi ^a   Jing, Xiabin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b JILIN UNIVERSITY   (China)

^c SOUTHEAST UNIVERSITY   (China)

Author keywords

Cervical cancer; Cisplatin; Local chemotherapy; Nanofibers; Vaginal delivery

Indexed keywords

CISPLATIN; MACROGOL; NANOFIBER; POLYLACTIDE; ANTINEOPLASTIC AGENT; DRUG CARRIER; MACROGOL DERIVATIVE; MUCIN; POLYESTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER SIZE; CARCINOGENESIS; CERVICAL CANCER CELL LINE; CONTACT ANGLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; ELECTROSPINNING; EX VIVO STUDY; FEMALE; FLUORESCENCE IMAGING; IN VITRO STUDY; IN VIVO STUDY; LOCAL THERAPY; MOUSE; MUCOADHESION; NONHUMAN; PH; PILOT STUDY; UTERINE CERVIX CANCER; WEIGHT REDUCTION; WETTABILITY; ADHESION; ANIMAL; CHEMISTRY; INTRAVAGINAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; NANOMEDICINE; PATHOLOGY; PHARMACEUTICS; PROCEDURES; SOLUBILITY; TISSUE DISTRIBUTION; TUMOR CELL LINE; TUMOR VOLUME; UTERINE CERVICAL NEOPLASMS;

ADHESIVENESS; ADMINISTRATION, INTRAVAGINAL; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CISPLATIN; DRUG CARRIERS; FEMALE; MICE; MUCINS; NANOFIBERS; NANOMEDICINE; PILOT PROJECTS; POLYESTERS; POLYETHYLENE GLYCOLS; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TISSUE DISTRIBUTION; TUMOR BURDEN; UTERINE CERVICAL NEOPLASMS;

EID: 84926506088     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.03.029     Document Type: Article

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