메뉴 건너뛰기




Volumn 395, Issue 10, 2014, Pages 1221-1231

Membrane-type I matrix metalloproteinase-dependent ectodomain shedding of mucin16/CA-125 on ovarian cancer cells modulates adhesion and invasion of peritoneal mesothelium

Author keywords

Biomarker; Meso mimetic; Metastasis; MMP 14; Proteolysis

Indexed keywords

CA 125 ANTIGEN; GLYCOPROTEIN; MATRIX METALLOPROTEINASE 14; MUCIN; MUCIN16; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; MMP14 PROTEIN, HUMAN; MUC16 PROTEIN, HUMAN;

EID: 84926486395     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2014-0155     Document Type: Conference Paper
Times cited : (32)

References (55)
  • 1
    • 27744592127 scopus 로고    scopus 로고
    • Role of integrin receptors for fibronectin, collagen and laminin in the regulation of ovarian carcinoma functions in response to a matrix microenvironment
    • Ahmed, N., Riley, C., Rice, G., and Quinn, M. (2005). Role of integrin receptors for fibronectin, collagen and laminin in the regulation of ovarian carcinoma functions in response to a matrix microenvironment. Clin. Exp. Metastasis 22, 391-402.
    • (2005) Clin. Exp. Metastasis , vol.22 , pp. 391-402
    • Ahmed, N.1    Riley, C.2    Rice, G.3    Quinn, M.4
  • 3
    • 0035008525 scopus 로고    scopus 로고
    • Ovarian surface epithelium: Biology, endocrinology, and pathology
    • Auersperg, N., Wong, A.S., Choi, K.C., Kang, S.K., and Leung, P.C. (2001). Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr. Rev. 22, 255-288.
    • (2001) Endocr. Rev. , vol.22 , pp. 255-288
    • Auersperg, N.1    Wong, A.S.2    Choi, K.C.3    Kang, S.K.4    Leung, P.C.5
  • 4
    • 33947518899 scopus 로고    scopus 로고
    • Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression
    • Barbolina, M.V., Adley, B.P., Ariztia, E.V., Liu, Y., and Stack, M.S. (2007). Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression. J. Biol. Chem. 282, 4924-4931.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4924-4931
    • Barbolina, M.V.1    Adley, B.P.2    Ariztia, E.V.3    Liu, Y.4    Stack, M.S.5
  • 8
    • 84861860715 scopus 로고    scopus 로고
    • The changing view of high-grade serous ovarian cancer
    • Berns, E.M.J.J. and Bowtell, D.D. (2012). The changing view of high-grade serous ovarian cancer. Cancer Res. 72, 2701-2704.
    • (2012) Cancer Res. , vol.72 , pp. 2701-2704
    • Berns, E.M.J.J.1    Bowtell, D.D.2
  • 9
    • 1842529995 scopus 로고    scopus 로고
    • Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers
    • Burleson, K.M., Casey, R.C., Skubitz, K.M., Pambuccian, S.E., Oegema, T.R., and Skubitz, A.P.N. (2004a). Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers. Gynecol. Oncol. 93, 170-181.
    • (2004) Gynecol. Oncol. , vol.93 , pp. 170-181
    • Burleson, K.M.1    Casey, R.C.2    Skubitz, K.M.3    Pambuccian, S.E.4    Oegema, T.R.5    Skubitz, A.P.N.6
  • 10
    • 19944423801 scopus 로고    scopus 로고
    • Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers
    • Burleson, K.M., Hansen, L.K., and Skubitz, A.P.N. (2004b). Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers. Clin. Exp. Metastasis. 21, 685-697.
    • (2004) Clin. Exp. Metastasis. , vol.21 , pp. 685-697
    • Burleson, K.M.1    Hansen, L.K.2    Skubitz, A.P.N.3
  • 11
    • 19744368302 scopus 로고    scopus 로고
    • Cancer of the ovary
    • Cannistra, S.A. (2004). Cancer of the ovary. N. Engl. J. Med. 351, 2519-2529.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2519-2529
    • Cannistra, S.A.1
  • 13
    • 84878623168 scopus 로고    scopus 로고
    • Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation
    • Chen, S.-H., Hung, W.-C., Wang, P., Paul, C., and Konstantopoulos, K. (2013). Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation. Sci. Rep. 3, 1870.
    • (2013) Sci. Rep. , vol.3 , pp. 1870
    • Chen, S.-H.1    Hung, W.-C.2    Wang, P.3    Paul, C.4    Konstantopoulos, K.5
  • 15
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier, J.S. and Cheresh, D.A. (2010). Integrins in cancer: biological implications and therapeutic opportunities. Nat. Rev. Cancer 10, 9-22.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 16
    • 0026697959 scopus 로고
    • Circulating mucins as tumor markers in ovarian cancer
    • (review)
    • Devine, P.L., McGuckin, M.A., and Ward, B.G. (1992). Circulating mucins as tumor markers in ovarian cancer (review). Anticancer Res. 12, 709-717.
    • (1992) Anticancer Res. , vol.12 , pp. 709-717
    • Devine, P.L.1    McGuckin, M.A.2    Ward, B.G.3
  • 18
    • 56749103412 scopus 로고    scopus 로고
    • The cell of origin of ovarian epithelial tumours
    • Dubeau, L. (2008). The cell of origin of ovarian epithelial tumours. Lancet Oncol. 9, 1191-1197.
    • (2008) Lancet Oncol. , vol.9 , pp. 1191-1197
    • Dubeau, L.1
  • 19
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad, M. and Werb, Z. (2002). New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2, 161-174.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 20
    • 0035816605 scopus 로고    scopus 로고
    • Functional interplay between type I collagen and cell surface matrix metalloproteinase activity
    • Ellerbroek, S.M., Wu, Y.I., Overall, C.M., and Stack, M.S. (2001). Functional interplay between type I collagen and cell surface matrix metalloproteinase activity. J. Biol. Chem. 276, 24833-28342.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24833-28342
    • Ellerbroek, S.M.1    Wu, Y.I.2    Overall, C.M.3    Stack, M.S.4
  • 21
    • 0015230305 scopus 로고
    • Incessant ovulation - A factor in ovarian neoplasia?
    • Fathalla, M.F. (1971). Incessant ovulation - a factor in ovarian neoplasia? Lancet ii, 163.
    • (1971) Lancet , vol.II , pp. 163
    • Fathalla, M.F.1
  • 22
    • 77953448088 scopus 로고    scopus 로고
    • Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies
    • Goodell, C.A., Belisle, J.A., Gubbels, J.A., Migneault, M., Rancourt, C., Connor, J., Kunnimalaiyaan, M., Kravitz, R., Tucker, W., Zwick, M., et al. (2009). Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies. J. Ovarian Res. 2, 8.
    • (2009) J. Ovarian Res. , vol.2 , pp. 8
    • Goodell, C.A.1    Belisle, J.A.2    Gubbels, J.A.3    Migneault, M.4    Rancourt, C.5    Connor, J.6    Kunnimalaiyaan, M.7    Kravitz, R.8    Tucker, W.9    Zwick, M.10
  • 24
    • 84857925901 scopus 로고    scopus 로고
    • Nonovarian origins of ovarian cancer
    • Hillier, S.G. (2012). Nonovarian origins of ovarian cancer. Proc. Natl. Acad. Sci. USA 109, 3608-3609.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 3608-3609
    • Hillier, S.G.1
  • 26
    • 47549085187 scopus 로고    scopus 로고
    • Phenotypic plasticity of neoplastic ovarian epithelium: Unique cadherin profiles in tumor progression
    • Hudson, L.G., Zeineldin, R., and Stack, M.S. (2008). Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression. Clin. Exp. Metastasis 25, 643-655.
    • (2008) Clin. Exp. Metastasis , vol.25 , pp. 643-655
    • Hudson, L.G.1    Zeineldin, R.2    Stack, M.S.3
  • 27
    • 78649906756 scopus 로고    scopus 로고
    • Status of tumor markers in epithelial ovarian cancer has there been any progress? A review
    • Husseinzadeh, N. (2011). Status of tumor markers in epithelial ovarian cancer has there been any progress? A review. Gynecol. Oncol. 120, 152-157.
    • (2011) Gynecol. Oncol. , vol.120 , pp. 152-157
    • Husseinzadeh, N.1
  • 29
    • 84876954181 scopus 로고    scopus 로고
    • Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer
    • Kaimal, R., Aljumaily, R., Tressel, S.L., Pradhan, R.V., Covic, L., Kuliopulos, A., Zarwan, C., Kim, Y.B., Sharifi, S., and Agarwal, A. (2013). Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer. Cancer Res. 73, 2457-2467.
    • (2013) Cancer Res. , vol.73 , pp. 2457-2467
    • Kaimal, R.1    Aljumaily, R.2    Tressel, S.L.3    Pradhan, R.V.4    Covic, L.5    Kuliopulos, A.6    Zarwan, C.7    Kim, Y.B.8    Sharifi, S.9    Agarwal, A.10
  • 34
    • 0032588952 scopus 로고    scopus 로고
    • CD44 and beta1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells
    • Lessan, K., Aguiar, D.J., Oegema, T., Siebenson, L., and Skubitz, A.P. (1999). CD44 and beta1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells. Am. J. Pathol. 154, 1525-1537.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1525-1537
    • Lessan, K.1    Aguiar, D.J.2    Oegema, T.3    Siebenson, L.4    Skubitz, A.P.5
  • 35
    • 79953064291 scopus 로고    scopus 로고
    • Challenges related to developing serum-based biomarkers for early ovarian cancer detection
    • Mai, P.L., Wentzensen, N., and Greene, M.H. (2011). Challenges related to developing serum-based biomarkers for early ovarian cancer detection. Cancer Prev. Res. (Phila.) 4, 303-306.
    • (2011) Cancer Prev. Res. (Phila.) , vol.4 , pp. 303-306
    • Mai, P.L.1    Wentzensen, N.2    Greene, M.H.3
  • 36
    • 0024377242 scopus 로고
    • Modulation of ovarian carcinoma tumor marker CA-125 by γ modulation of ovarian carcinoma tumor marker CA-125 by 7-interferon
    • Marth, C., Fuith, L.C., Böck, G., and Dapunt, O. (1989). Modulation of ovarian carcinoma tumor marker CA-125 by γ modulation of ovarian carcinoma tumor marker CA-125 by 7-interferon. Cancer Res. 105, 6538-6542.
    • (1989) Cancer Res. , vol.105 , pp. 6538-6542
    • Marth, C.1    Fuith, L.C.2    Böck, G.3    Dapunt, O.4
  • 37
    • 34248350830 scopus 로고    scopus 로고
    • Modulation of CA-125 tumor marker shedding in ovarian cancer cells by erlotinib or cetuximab
    • Marth, C., Egle, D., Auer, D., Rössler, J., Zeimet, A.G., Vergote, I., and Daxenbichler, G. (2007). Modulation of CA-125 tumor marker shedding in ovarian cancer cells by erlotinib or cetuximab. Gynecol. Oncol. 105, 716-721.
    • (2007) Gynecol. Oncol. , vol.105 , pp. 716-721
    • Marth, C.1    Egle, D.2    Auer, D.3    Rössler, J.4    Zeimet, A.G.5    Vergote, I.6    Daxenbichler, G.7
  • 38
    • 74249095507 scopus 로고    scopus 로고
    • Current state of biomarker development for clinical application in epithelial ovarian cancer
    • Moore, R.G., MacLaughlan, S., and Bast, R.C. (2010). Current state of biomarker development for clinical application in epithelial ovarian cancer. Gynecol. Oncol. 116, 240-245.
    • (2010) Gynecol. Oncol. , vol.116 , pp. 240-245
    • Moore, R.G.1    MacLaughlan, S.2    Bast, R.C.3
  • 39
    • 0029741632 scopus 로고    scopus 로고
    • Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the alpha2beta1 integrin
    • Moser, T.L., Pizzo, S.V., Bafetti, L.M., Man, D.A.F., and Sharon, M. (1996). Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the alpha2beta1 integrin. Int. J. Cancer 701, 695-701.
    • (1996) Int. J. Cancer , vol.701 , pp. 695-701
    • Moser, T.L.1    Pizzo, S.V.2    Bafetti, L.M.3    Man, D.A.F.4    Sharon, M.5
  • 40
    • 66949150704 scopus 로고    scopus 로고
    • Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: A potential role in I.p. metastatic dissemination
    • Moss, N.M., Barbolina, M.V., Liu, Y., Sun, L., Munshi, H.G., and Stack, M.S. (2009a). Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination. Cancer Res. 69, 7121-7129.
    • (2009) Cancer Res. , vol.69 , pp. 7121-7129
    • Moss, N.M.1    Barbolina, M.V.2    Liu, Y.3    Sun, L.4    Munshi, H.G.5    Stack, M.S.6
  • 41
    • 67749137602 scopus 로고    scopus 로고
    • Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices
    • Moss, N.M., Wu, Y.I., Liu, Y., Munshi, H.G., and Stack, M.S. (2009b). Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices. J. Biol. Chem. 284, 19791-19799.
    • (2009) J. Biol. Chem. , vol.284 , pp. 19791-19799
    • Moss, N.M.1    Wu, Y.I.2    Liu, Y.3    Munshi, H.G.4    Stack, M.S.5
  • 44
    • 0034296445 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary
    • Sakata, K., Shigemasa, K., Nagai, N., and Ohama, K. (2000). Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary. Int. J. Oncol. 17, 673-381.
    • (2000) Int. J. Oncol. , vol.17 , pp. 673-1381
    • Sakata, K.1    Shigemasa, K.2    Nagai, N.3    Ohama, K.4
  • 45
    • 64649101697 scopus 로고    scopus 로고
    • CA125 in ovarian cancer
    • Scholler, N. and Urban, N. (2007). CA125 in ovarian cancer. Biomark. Med. 1, 513-523.
    • (2007) Biomark. Med. , vol.1 , pp. 513-523
    • Scholler, N.1    Urban, N.2
  • 46
    • 33845672642 scopus 로고    scopus 로고
    • Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery
    • Scholler, N., Garvik, B., Hayden-Ledbetter, M., Kline, T., and Urban, N. (2007). Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery. Cancer Lett. 247, 130-136.
    • (2007) Cancer Lett. , vol.247 , pp. 130-136
    • Scholler, N.1    Garvik, B.2    Hayden-Ledbetter, M.3    Kline, T.4    Urban, N.5
  • 47
    • 18344366604 scopus 로고    scopus 로고
    • MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression
    • Sounni, N.E., Devy, L., Hajitou, A., Frankenne, F., Munaut, C., Gilles, C., Deroanne, C., Thompson, E.W., Foidart, J.M., and Noel, A. (2002). MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression. FASEB J. 16, 555-564.
    • (2002) FASEB J. , vol.16 , pp. 555-564
    • Sounni, N.E.1    Devy, L.2    Hajitou, A.3    Frankenne, F.4    Munaut, C.5    Gilles, C.6    Deroanne, C.7    Thompson, E.W.8    Foidart, J.M.9    Noel, A.10
  • 49
    • 0032588084 scopus 로고    scopus 로고
    • Beta1-integrins partly mediate binding of ovarian cancer cells to peritoneal mesothelium in vitro
    • Strobel, T. and Cannistra, S.A. (1999). Beta1-integrins partly mediate binding of ovarian cancer cells to peritoneal mesothelium in vitro. Gynecol. Oncol. 73, 362-367.
    • (1999) Gynecol. Oncol. , vol.73 , pp. 362-367
    • Strobel, T.1    Cannistra, S.A.2
  • 51
    • 0029092566 scopus 로고
    • Tumor markers in the management of patients with ovarian cancer
    • Tuxen, M.K., Sölétormos, G., and Dombernowsky, P. (1995). Tumor markers in the management of patients with ovarian cancer. Cancer Treat. Rev. 21, 215-245.
    • (1995) Cancer Treat. Rev. , vol.21 , pp. 215-245
    • Tuxen, M.K.1    Sölétormos, G.2    Dombernowsky, P.3
  • 53
    • 0035920171 scopus 로고    scopus 로고
    • Molecular cloning of the CA125 ovarian cancer antigen: Identification as a new mucin, MUC16
    • Yin, B.W. and Lloyd, K.O. (2001). Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16. J. Biol. Chem. 276, 27371-27375.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27371-27375
    • Yin, B.W.1    Lloyd, K.O.2
  • 54
    • 0037051691 scopus 로고    scopus 로고
    • Ovarian cancer antigen CA125 is encoded by the MUC16 mucin gene
    • Yin, B.W.T., Dnistrian, A., and Lloyd, K.O. (2002). Ovarian cancer antigen CA125 is encoded by the MUC16 mucin gene. Int. J. Cancer 98, 737-740.
    • (2002) Int. J. Cancer , vol.98 , pp. 737-740
    • Yin, B.W.T.1    Dnistrian, A.2    Lloyd, K.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.