The complex and specific pMHC interactions with diverse HIV-1 TCR clonotypes reveal a structural basis for alterations in CTL function

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Xia, Zhen ^a   Chen, Huabiao ^b   Kang, Seung Gu ^a   Huynh, Tien ^a   Fang, Justin W ^b   Lamothe, Pedro A ^b   Walker, Bruce D ^b,c   Zhou, Ruhong ^a,d  

^a IBM T J WATSON RESEARCH CENTER   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d Department of Chemistry Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA ANTIGEN CLASS 1; HLA B27 ANTIGEN; HLA-B*27:05 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE; PROTEIN BINDING;

BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; IMMUNOLOGY; METABOLISM; MOLECULAR DYNAMICS; MUTAGENESIS; PROTEIN QUATERNARY STRUCTURE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV-1; HLA-B27 ANTIGEN; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, ANTIGEN, T-CELL; THERMODYNAMICS;

EID: 84926483806     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04087     Document Type: Article

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