Maltodextrin fast dissolving films for quercetin nanocrystal delivery. A feasibility study

Carbohydrate Polymers

Volumn 121, Issue 1, 2015, Pages 217-223

  Lai, Francesco ^a   Franceschini, Ilaria ^b   Corrias, Francesco ^a   Sala, Maria Chiara ^b   Cilurzo, Francesco ^b   Sinico, Chiara ^a   Pini, Elena ^b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Fast dissolving films; Maltodextrins; Nanocrystals; Quercetin

Indexed keywords

BIOCHEMISTRY; DISSOLUTION; FLAVORS; LOADING; NANOCRYSTALS; PHENOLS; POLYSACCHARIDES; SPECTROSCOPIC ANALYSIS;

CALORIMETRIC ANALYSIS; ELONGATION AT BREAK; FEASIBILITY STUDIES; FILM-FORMING MATERIALS; HIGH PRESSURE HOMOGENIZER; MALTODEXTRINS; ORAL BIOAVAILABILITIES; QUERCETIN;

FLAVONOIDS;

MALTODEXTRIN; NANOPARTICLE; POLYSACCHARIDE; QUERCETIN; SUSPENSION;

CHEMISTRY; FEASIBILITY STUDY; SOLUBILITY; SUSPENSION;

FEASIBILITY STUDIES; NANOPARTICLES; POLYSACCHARIDES; QUERCETIN; SOLUBILITY; SUSPENSIONS;

EID: 84926466230     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2014.11.070     Document Type: Article

References (36)

1. Alexandre, M., & Dubois, P. (2000). Polymer-layered silicate nanocomposites: Preparation, properties and uses of a new class of materials. Materials Science and Engineering: R: Reports, 28(1-2), 1-63.
2. Cai, X., Fang, Z., Dou, J., Yu, A., & Zhai, G. (2013). Bioavailability of quercetin: Problems and promises. Current Medicinal Chemistry, 20(20), 2572-2582.
3. Chen, B., & Evans, J. R. G. (2005). Thermoplastic starch-clay nanocomposites and their characteristics. Carbohydrate Polymers, 61(4), 455-463.
4. Chessa, M., Caddeo, C., Valenti, D., Manconi, M., Sinico, C., & Fadda, A. M. (2011). Effect of penetration enhancer containing vesicles on the percutaneous delivery of quercetin through new born pig skin. Pharmaceutics, 3(3), 497-509.
5. Cilurzo, F., Cupone, I. E., Minghetti, P., Buratti, S., Selmin, F., Gennari, C. G. M., et al.(2010). Nicotine fast dissolving films made of maltodextrins: A feasibility study. AAPS PharmSciTech, 11(4), 1511-1517.
6. Cilurzo, F., Cupone, I. E., Minghetti, P., Selmin, F., & Montanari, L. (2008). Fast dissolving films made of maltodextrins. European Journal of Pharmaceutics and Biopharmaceutics, 70(3), 895-900.
7. Cyras, V. P., Manfredi, L. B., Ton-That, M.-T., & Vázquez, A. (2008). Physical and mechanical properties of thermoplastic starch/montmorillonite nanocomposite films. Carbohydrate Polymers, 73(1), 55-63.
8. De Mello Costa, A. R., Marquiafável, F. S., de Oliveira Lima Leite Vaz, M. M., Rocha, B. A., Pires Bueno, P. C., Amaral, P. L. M., et al. (2010). Quercetin-PVP K25 solid dispersions. Journal of Thermal Analysis and Calorimetry, 104(1), 273-278.
9. Fatma, S., Talegaonkar, S., Iqbal, Z., Panda, A. K., Negi, L. M., Goswami, D. G., et al. (2014). Novel flavonoid-based biodegradable nanoparticles for effective oral delivery of etoposide by P-glycoprotein modulation: An in vitro, ex vivo and in vivo investigations. Drug Delivery, 1-12.
10. Garnero, C., Chattah, A. K., & Longhi, M. (2013). Supramolecular complexes of maltodextrin and furosemide polymorphs: A new approach for delivery systems. Carbohydrate Polymers, 94(1), 292-300.
11. Harwood, M., Danielewska-Nikiel, B., Borzelleca, J. F., Flamm, G. W., Williams, G. M.,& Lines, T. C. (2007). A critical review of the data related to the safety of quercetin and quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food and Chemical Toxicology, 45(11), 2179-2205.
12. Jordan, J., Jacob, K. I., Tannenbaum, R., Sharaf, M. A., & Jasiuk, I. (2005). Experimental trends in polymer nanocomposites - A review. Materials Science and Engineering, A, 393(1-2), 1-11.
13. Kelly, G. S. (2011). Quercetin. Monograph. Alternative Medicine Review: A Journal of Clinical Therapeutic, 16(2), 172-194.
14. Kesisoglou, F., Panmai, S., & Wu, Y. (2007). Nanosizing - Oral formulation development and biopharmaceutical evaluation. Advanced Drug Delivery Reviews, 59(7), 631-644.
15. Kocbek, P., Baumgartner, S., & Kristl, J. (2006). Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs. International Journal of Pharmaceutics, 312(1-2), 179-186.
16. Lai, F., Pini, E., Corrias, F., Perricci, J., Manconi, M., Fadda, A. M., et al. (2014). Formulation strategy and evaluation of nanocrystal piroxicam orally disintegrating tablets manufacturing by freeze-drying. International Journal of Pharmaceutics, 467(1-2), 27-33.
17. Lai, F., Pini, E., Angioni, G., Manca, M. L., Perricci, J., Sinico, C., et al. (2011). Nanocrystals as tool to improve piroxicam dissolution rate in novel orally disintegrating tablets. European Journal of Pharmaceutics and Biopharmaceutics, 79(3), 552-558.
18. Leathers, T. D. (2003). Biotechnological production and applications of pullulan. Applied Microbiology and Biotechnology, 62(5-6), 468-473.
19. Li, B., Konecke, S., Harich, K., Wegiel, L., Taylor, L. S., & Edgar, K. J. (2013). Solid dispersion of quercetin in cellulose derivative matrices influences both solubility and stability. Carbohydrate Polymers, 92(2), 2033-2040.
20. Li, B., Zhang, L., Deng, Y., & Liang, N. (2004). Study on solid dispersion of quercetin-PEG (6000). Huaxi Yaoxue Zazhi, 19, 35-37.
21. Möschwitzer, J., Müller, R. H. (n.d.). Drug Nanocrystals - The Universal Formulation Approach for Poorly Soluble Drugs, Nanoparticulate Drug Delivery Systems, Informa Healthcare. (first edit.).
22. Müller, R. H., Gohla, S., & Keck, C. M. (2011). State of the art of nanocrystals-Special features, production, nanotoxicology aspects and intracellular delivery. European Journal of Pharmaceutics and Biopharmaceutics, 78(1), 1-9.
23. Nijveldt, R. J., van Nood, E., van Hoorn, D. E., Boelens, P. G., van Norren, K., & van Leeuwen, P. A. (2001). Flavonoids: A review of probable mechanisms of action and potential applications. American Journal of Clinical Nutrition, 74(4), 418-425.
24. Noyes, A. A., & Whitney, W. R. (1897). The rate of solution of solid substances in their own solutions. Journal of the American Chemical Society, 19(12), 930-934.
25. Okamoto, T. (2005). Safety of quercetin for clinical application. International Journal of Molecular Medicine, 16(2), 275-278 (Review).
26. Pinna, M., Pinna, F. (2009, November). Quick water-dissolving film containing cosmetic, aromatic, pharmaceutical or food substances. US7612048.
27. Ribeiro, M. E. N. P., Vieira, I. G. P., Cavalcante, I. M., Ricardo, N. M. P. S., Attwood, D., Yeates, S. G., et al. (2009). Solubilisation of griseofulvin, quercetin and rutin in micellar formulations of triblock copolymers E62P39E62 and E137S18E137. International Journal of Pharmaceutics, 378(1-2), 211-214.
28. Sahoo, N. G., Kakran, M., Shaal, L. A., Li, L., Müller, R. H., Pal, M., et al. (2011). Preparation and characterization of quercetin nanocrystals. Journal of Pharmaceutical Sciences, 100(6), 2379-2390.
29. Selmin, F., Franceschini, I., Cupone, I. E., Minghetti, P., & Cilurzo, F. (2015). Aminoacidsas non-traditional plasticizers of maltodextrins fast-dissolving films. Carbohydrate Polymers, 115, 613-616.
30. Shen, B., Shen, C., Yuan, X., Bai, J., Lv, Q., Xu, H., et al. (2013). Development and characterization of an orodispersible film containing drug nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 85(3 Pt. B), 1348-1356.
31. Utesch, D., Feige, K., Dasenbrock, J., Broschard, T. H., Harwood, M., Danielewska-Nikiel, B., et al. (2008). Evaluation of the potential in vivo genotoxicity of quercetin. Mutation Research, 654(1), 38-44.
32. Van Eerdenbrugh, B., Froyen, L., Van Humbeeck, J., Martens, J. A., Augustijns, P.,& Van den Mooter, G. (2008). Drying of crystalline drug nanosuspensions-the importance of surface hydrophobicity on dissolution behavior upon redispersion. European Journal of Pharmaceutical Sciences, 35(1-2), 127-135.
33. Wilhelm, H.-M., Sierakowski, M.-R., Souza, G. P., & Wypych, F. (2003). Starch films reinforced with mineral clay. Carbohydrate Polymers, 52(2), 101-110.
34. Wu, L., Zhang, J., & Watanabe, W. (2011). Physical and chemical stability of drug nanoparticles. Advanced Drug Delivery Reviews, 63(6), 456-469.
35. Zerbe, H. G., Guo, J. H. (1998, May). Zubereitung zur Anwendung in der Mundhöhlemit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zurdosierten Abgabe enthaltenden Schicht. DE19646392.
36. Zheng, Y., & Chow, A. H. L. (2009). Production and characterization of a spray-dried hydroxypropyl-beta-cyclodextrin/quercetin complex. Drug Developmentand Industrial Pharmacy, 35(6), 727-734.