Formulation strategy and evaluation of nanocrystal piroxicam orally disintegrating tablets manufacturing by freeze-drying

International Journal of Pharmaceutics

Volumn 467, Issue 1-2, 2014, Pages 27-33

  Lai, Francesco ^a   Pini, Elena ^b   Corrias, Francesco ^a   Perricci, Jacopo ^b   Manconi, Maria ^a   Fadda, Anna Maria ^a   Sinico, Chiara ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Excipients; Nanocrystal; Nanosuspensions; Orally disintegrating tablet; Piroxicam

Indexed keywords

ASPARTAME; CITRIC ACID; EXCIPIENT; GELATIN; MACROGOL 4000; MALTODEXTRIN; MANNITOL; NANOCRYSTAL; PIROXICAM; POLOXAMER; XANTHAN; BACTERIAL POLYSACCHARIDE; CARBOXYMETHYLCELLULOSE; NANOPARTICLE; NONSTEROID ANTIINFLAMMATORY AGENT; TABLET;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG SOLUBILITY; ELECTROPHORETIC MOBILITY; FREEZE DRYING; IN VITRO STUDY; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; TABLET DISINTEGRATION; TABLET MANUFACTURE; X RAY DIFFRACTION; ZETA POTENTIAL; CHEMISTRY; COMPARATIVE STUDY; INFRARED SPECTROSCOPY; KINETICS; MEDICINAL CHEMISTRY; NANOTECHNOLOGY; ORAL DRUG ADMINISTRATION; PH; PHARMACEUTICS; POWDER DIFFRACTION; PROCEDURES; SOLUBILITY; TABLET; X RAY CRYSTALLOGRAPHY;

ADMINISTRATION, ORAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALORIMETRY, DIFFERENTIAL SCANNING; CARBOXYMETHYLCELLULOSE SODIUM; CHEMISTRY, PHARMACEUTICAL; CRYSTALLOGRAPHY, X-RAY; EXCIPIENTS; FREEZE DRYING; GELATIN; HYDROGEN-ION CONCENTRATION; KINETICS; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; PIROXICAM; POLOXAMER; POLYSACCHARIDES, BACTERIAL; POWDER DIFFRACTION; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84898727676     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.03.047     Document Type: Article

References (21)

1. V. Ambrogi, L. Perioli, F. Marmottini, S. Giovagnoli, M. Esposito, and C. Rossi Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate European Journal of Pharmaceutical Sciences 32 2007 216 222
2. G.L. Amidon, H. Lennernäs, V.P. Shah, and J.R. Crison A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability Pharmaceutical Research 12 1995 413 420
3. S. Corveleyn, and J. Remon Formulation of a lyophilized dry emulsion tablet for the delivery of poorly soluble drugs International Journal of Pharmaceutics 166 1998 65 74
4. I. Graf A.R. Gennaro, Remington's Pharmaceutical Sciences 17th ed. 1985 Mack Publishing Comp. Easton, Pennsylvania
5. C.M. Keck, and R.H. Müller Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation European Journal of Pharmaceutics and Biopharmaceutics 62 2006 3 16
6. P. Kocbek, S. Baumgartner, and J. Kristl Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs International Journal of Pharmaceutics 312 2006 179 186
7. F. Lai, E. Pini, G. Angioni, M.L. Manca, J. Perricci, C. Sinico, and A.M. Fadda Nanocrystals as tool to improve piroxicam dissolution rate in novel orally disintegrating tablets European Journal of Pharmaceutics and Biopharmaceutics 79 2011 552 558
8. F. Lai, R. Pireddu, F. Corrias, A.M. Fadda, D. Valenti, E. Pini, and C. Sinico Nanosuspension improves tretinoin photostability and delivery to the skin International Journal of Pharmaceutics 458 2013 104 109
9. F. Lai, C. Sinico, G. Ennas, F. Marongiu, G. Marongiu, and A.M. Fadda Diclofenac nanosuspensions: influence of preparation procedure and crystal form on drug dissolution behaviour International Journal of Pharmaceutics 373 2009 124 132
10. R. Mauludin, R.H. Müller, and C.M. Keck Development of an oral rutin nanocrystal formulation International Journal of Pharmaceutics 370 2009 202 209
11. R. Mauludin, R.H. Müller, and C.M. Keck Kinetic solubility and dissolution velocity of rutin nanocrystals European Journal of Pharmaceutical Sciences 36 2009 502 510
12. E. Merisko-Liversidge, G.G. Liversidge, and E.R. Cooper Nanosizing: a formulation approach for poorly-water-soluble compounds European Journal of Pharmaceutical Sciences 18 2003 113
13. A.A. Noyes, and W.R. Whitney The rate of solution of solid substances in their own solutions Journal of the American Chemical Society 19 1897 930 934
14. Owen, M., Michael, H., Richard, G., Patrich, K., 2000. Fast disperding dosage forms containg fish gelatin. WO 00/61117.
15. R.H. Muller, C. Jacobs, and O. Kayser Modified-Release Drug Delivery Technology 2003 Marcel Dekker
16. M. Sugimoto, S. Narisawa, K. Matsubara, H. Yoshino, M. Nakano, and T. Handa Development of manufacturing method for rapidly disintegrating oral tablets using the crystalline transition of amorphous sucrose International Journal of Pharmaceutics 320 2006 71 78
17. V. Tantishaiyakul, N. Kaewnopparat, and S. Ingkatawornwong Properties of solid dispersions of piroxicam in polyvinylpyrrolidone International Journal of Pharmaceutics 181 1999 143 151
18. R.R. Thakur, and M. Kashi An unlimited scope for novel formulations as orally disintegrating systems: present and future prospects Journal of Applied Pharmaceutical Science 1 2011 13 19
19. B. Van Eerdenbrugh, G. Van den Mooter, and P. Augustijns Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products International Journal of Pharmaceutics 364 2008 64 75
20. F. Vrečer, S. Srčič, and J. Sčmid-Korbar Investigation of piroxicam polymorphism International Journal of Pharmaceutics 68 1991 35 41
21. F. Vrečer, M. Vrbinc, and A. Meden Characterization of piroxicam crystal modifications International Journal of Pharmaceutics 256 2003 3 15