Increased autoimmune diabetes in pIgR-deficient NOD mice is due to a "hitchhiking" interval that refines the genetic effect of Idd5.4

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Simpfendorfer, Kim R ^a,c   Strugnell, Richard A ^a   Brodnicki, Thomas C ^b   Wijburg, Odilia L C ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; SECRETORY COMPONENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DIABETES; C57BL 6 MOUSE; CHROMOSOME 1; CONGENIC STRAIN; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; DISEASE PREDISPOSITION; FEMALE; GENE LOCUS; HEREDITY; MALE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; NULL ALLELE; SELECTIVE SWEEP; AGE; ALLELE; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; CHROMOSOMAL MAPPING; CHROMOSOME; DEFICIENCY; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; GENOME; HUMAN; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; TRANSGENIC MOUSE;

MUS;

AGE FACTORS; ALLELES; ANIMALS; CHROMOSOME MAPPING; CHROMOSOMES, MAMMALIAN; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME; HUMANS; IMMUNOGLOBULIN A; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, TRANSGENIC; RECEPTORS, POLYMERIC IMMUNOGLOBULIN;

EID: 84926443680     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121979     Document Type: Article

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