A concise flow synthesis of efavirenz

Angewandte Chemie - International Edition

Volumn 54, Issue 16, 2015, Pages 4945-4948

  Correia, Camille A ^a   Gilmore, Kerry ^a   McQuade, D Tyler ^c   Seeberger, Peter H ^a,b  

^a MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c FLORIDA STATE UNIVERSITY   (United States)

Author keywords

API synthesis; carbamates; copper; flow chemistry; homogeneous catalysis

Indexed keywords

CATALYSIS; COPPER; DRUG PRODUCTS; REACTION KINETICS;

ARYL ISOCYANATES; CARBAMATES; FLOW CHEMISTRY; HOMOGENEOUS CATALYSIS; INTRAMOLECULAR CYCLIZATIONS; LIFE SAVING DRUGS; PROOF OF PRINCIPLES; SEMI-CONTINUOUS PROCESS;

CYCLIZATION;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOXAZINE DERIVATIVE; CARBAMIC ACID DERIVATIVE; COPPER; EFAVIRENZ; ISOCYANIC ACID DERIVATIVE;

CATALYSIS; CHEMISTRY; CYCLIZATION; SYNTHESIS;

ANTI-HIV AGENTS; BENZOXAZINES; CARBAMATES; CATALYSIS; COPPER; CYCLIZATION; ISOCYANATES;

EID: 84926443285     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201411728     Document Type: Article

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