SCOPUS 정보 검색 플랫폼

Volumn 4, Issue 7, 2013, Pages 2822-2827

End-to-end continuous flow synthesis and purification of diphenhydramine hydrochloride featuring atom economy, in-line separation, and flow of molten ammonium salts

(2) Snead, David R a Jamison, Timothy F a

a MASSACHUSETTS INSTITUTE OF TECHNOLOGY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; AMERICAN CHEMICAL SOCIETY; CONTINUOUS-FLOW SYNTHESIS; DIPHENHYDRAMINE HYDROCHLORIDES; GREEN CHEMISTRY; HIGH TEMPERATURE; MATERIAL STREAMS; WASTE MINIMIZATION;

CONSERVATION; FUSED SALTS; IONIC LIQUIDS;

PURIFICATION;

EID: 84878809904 PISSN: 20416520 EISSN: 20416539 Source Type: Journal
DOI: 10.1039/c3sc50859e Document Type: Article

Times cited : (89)

References (48)

1
- 85035195889
- G. Rieveschl, US Pat., 2 421 714, 1947
- (1947) US Pat , vol.2 , Issue.421 , pp. 714
- Rieveschl, G.¹

2
- 0003980673
- Oxford University Press, New York
- P. T. Anastas, and J. C. Warner, Green Chemistry: Theory and Practice, Oxford University Press, New York 1998
- (1998) Green Chemistry: Theory and Practice
- Anastas, P.T.¹ Warner, J.C.²

3
- 22744441634
- K. Plumb Chem. Eng. Res. Des. 2005 83 A6 730-738
- (2005) Chem. Eng. Res. Des , vol.83 , Issue.A6 , pp. 730-738
- Plumb, K.¹

4
- 15944366532
- D. M. Roberge, L. Ducry, N. Bieler, P. Cretton, B. Zimmermann Chem. Eng. Technol. 2005 28 318-323
- (2005) Chem. Eng. Technol , vol.28 , pp. 318-323
- Roberge, D.M.¹ Ducry, L.² Bieler, N.³ Cretton, P.⁴ Zimmermann, B.⁵

5
- 58149114898
- D. M. Roberge, B. Zimmermann, F. Rainone, M. Gottsponer, M. Eyholzer, N. Kockmann Org. Process Res. Dev. 2008 12 905-910
- (2008) Org. Process Res. Dev , vol.12 , pp. 905-910
- Roberge, D.M.¹ Zimmermann, B.² Rainone, F.³ Gottsponer, M.⁴ Eyholzer, M.⁵ Kockmann, N.⁶

6
- 80052348570
- S. D. Schaber, D. I. Gerogiorgis, R. Ramachandran, J. M. B. Evans, P. I. Barton, B. L. Trout Ind. Eng. Chem. Res. 2011 50 10083-10092
- (2011) Ind. Eng. Chem. Res , vol.50 , pp. 10083-10092
- Schaber, S.D.¹ Gerogiorgis, D.I.² Ramachandran, R.³ Evans, J.M.B.⁴ Barton, P.I.⁵ Trout, B.L.⁶

7
- 0034102820
- A. I. Stankiewicz, J. A. Moulijn Chem. Eng. Prog. 2000 22-34
- (2000) Chem. Eng. Prog , pp. 22-34
- Stankiewicz, A.I.¹ Moulijn, J.A.²

8
- 70350650700
- V. Hessel Chem. Eng. Technol. 2009 32 1655-1681
- (2009) Chem. Eng. Technol , vol.32 , pp. 1655-1681
- Hessel, V.¹

9
- 74549122023
- I. Plazl, A. Pohar Chem. Biochem. Eng. Q. 2009 23 537-544
- (2009) Chem. Biochem. Eng. Q , vol.23 , pp. 537-544
- Plazl, I.¹ Pohar, A.²

10
- 0035037776
- K. F. Jensen Chem. Eng. Sci. 2001 56 293-303
- (2001) Chem. Eng. Sci , vol.56 , pp. 293-303
- Jensen, K.F.¹

11
- 37649010665
- L. Kang, B. G. Chung, R. Langer, A. Khademhosseini Drug Discovery Today 2008 13 1-13
- (2008) Drug Discovery Today , vol.13 , pp. 1-13
- Kang, L.¹ Chung, B.G.² Langer, R.³ Khademhosseini, A.⁴

12
- 33747117373
- G. M. Whitesides Nature 2006 442 368-373
- (2006) Nature , vol.442 , pp. 368-373
- Whitesides, G.M.¹

13
- 34447109277
- B. P. Mason, K. E. Price, J. L. Steinbacher, A. R. Bogdan, D. T. McQuade Chem. Rev. 2007 107 2300-2318
- (2007) Chem. Rev , vol.107 , pp. 2300-2318
- Mason, B.P.¹ Price, K.E.² Steinbacher, J.L.³ Bogdan, A.R.⁴ McQuade, D.T.⁵

14
- 33847234609
- P. Watts, C. Wiles Org. Biomol. Chem. 2007 5 727-732
- (2007) Org. Biomol. Chem , vol.5 , pp. 727-732
- Watts, P.¹ Wiles, C.²

15
- 70349471035
- R. L. Hartman, K. F. Jensen Lab Chip 2009 9 2495-2507
- (2009) Lab Chip , vol.9 , pp. 2495-2507
- Hartman, R.L.¹ Jensen, K.F.²

16
- 79551614063
- D. Webb, T. F. Jamison Chem. Sci. 2010 1 675-680
- (2010) Chem. Sci , vol.1 , pp. 675-680
- Webb, D.¹ Jamison, T.F.²

17
- 79953702549
- J. Wegner, S. Ceylan, A. Kirschning Chem. Commun. 2011 47 4583-4592
- (2011) Chem. Commun , vol.47 , pp. 4583-4592
- Wegner, J.¹ Ceylan, S.² Kirschning, A.³

18
- 79961218749
- R. L. Hartman, J. P. McMullen, K. F. Jensen Angew. Chem., Int. Ed. 2011 50 7502-7519
- (2011) Angew. Chem., Int. Ed , vol.50 , pp. 7502-7519
- Hartman, R.L.¹ McMullen, J.P.² Jensen, K.F.³

19
- 79958003609
- CRC Press, Boca Raton
- C. Wiles, and P. Watts, Micro Reaction Technology in Organic Synthesis, CRC Press, Boca Raton 2011
- (2011) Micro Reaction Technology in Organic Synthesis
- Wiles, C.¹ Watts, P.²

20
- 85035191584
- accessed 21 December
- American Chemical Society, Sustainable Manufacturing: Roadmaps, http://www.acs.org/smrt, accessed 21 December 2012
- (2012) Sustainable Manufacturing: Roadmaps

21
- 79960496475
- C. Jiménez-González, P. Poechlauer, Q. B. Broxterman, B.-S. Yang, D. am Ende, J. Baird, C. Bertsch, R. E. Hannah, P. Dell'Orco, H. Noorman, S. Yee, R. Reintjens, A. Wells, V. Massonneau, J. Manley Org. Process Res. Dev. 2011 15 900-911
- (2011) Org. Process Res. Dev , vol.15 , pp. 900-911
- Jiménez-González, C.¹ Poechlauer, P.² Broxterman, Q.B.³ Yang, B.-S.⁴ Am Ende, D.⁵ Baird, J.⁶ Bertsch, C.⁷ Hannah, R.E.⁸ Dell'orco, P.⁹ Noorman, H.¹⁰ Yee, S.¹¹ Reintjens, R.¹² Wells, A.¹³ Massonneau, V.¹⁴ Manley, J.¹⁵

22
- 85035224114
- 2007MU01210 A
- S. Shankar, S. J. Pandurang, and M. D. Namdeo, IN Pat., 2007MU01210 A, 2009
- (2009) IN Pat
- Shankar, S.¹ Pandurang, S.J.² Namdeo, M.D.³

23
- 85035230361
- 2 176 477 A
- R. N. Brummel, and J. Vande Vusse, GB Pat., 2 176 477 A, 1986
- (1986) Vusse, GB Pat
- Brummel, R.N.¹ Vande, J.²

24
- 17844402958
- A. Große Böwing, A. Jess Green Chem. 2005 7 230-235
- (2005) Green Chem , vol.7 , pp. 230-235
- Große Böwing, A.¹ Jess, A.²

25
- 34848836141
- D. A. Waterkamp, M. Heiland, M. Schlüter, J. C. Sauvageau, T. Beyersdorff, J. Thöming Green Chem. 2007 9 1084-1090
- (2007) J. Thöming Green Chem , vol.9 , pp. 1084-1090
- Waterkamp, D.A.¹ Heiland, M.² Schlüter, M.³ Sauvageau, J.C.⁴ Beyersdorff, T.⁵

26
- 34547699647
- A. Renken, V. Hessel, P. Löb, R. Miszczuk, M. Uerdingen, L. Kiwi-Minsker Chem. Eng. Process. 2007 46 840-845
- (2007) Chem. Eng. Process , vol.46 , pp. 840-845
- Renken, A.¹ Hessel, V.² Löb, P.³ Miszczuk, R.⁴ Uerdingen, M.⁵ Kiwi-Minsker, L.⁶

27
- 61449094843
- M. A. Gonzalez, J. T. Ciszewski Org. Process Res. Dev. 2009 13 64-66
- (2009) Org. Process Res. Dev , vol.13 , pp. 64-66
- Gonzalez, M.A.¹ Ciszewski, J.T.²

28
- 70449435079
- D. Wilms, J. Klos, A. F. M. Kilbinger, H. Löwe, H. Frey Org. Process Res. Dev. 2009 13 961-964
- (2009) Org. Process Res. Dev , vol.13 , pp. 961-964
- Wilms, D.¹ Klos, J.² Kilbinger, A.F.M.³ Löwe, H.⁴ Frey, H.⁵

29
- 74249083208
- H. Löwe, R. D. Axinte, D. Breuch, C. Hofmann Chem. Eng. J. 2009 155 548-550
- (2009) Chem. Eng. J , vol.155 , pp. 548-550
- Löwe, H.¹ Axinte, R.D.² Breuch, D.³ Hofmann, C.⁴

30
- 71049183488
- D. A. Waterkamp, M. Engelbert, J. Thöming Chem. Eng. Technol. 2009 32 1717-1723
- (2009) Chem. Eng. Technol , vol.32 , pp. 1717-1723
- Waterkamp, D.A.¹ Engelbert, M.² Thöming, J.³

31
- 77956904292
- J. Zimmermann, B. Ondruschka, A. Stark Org. Process Res. Dev. 2010 14 1102-1109
- (2010) Org. Process Res. Dev , vol.14 , pp. 1102-1109
- Zimmermann, J.¹ Ondruschka, B.² Stark, A.³

32
- 77954540503
- S. Hu, A. Wang, H. Löwe, X. Li, Y. Wang, C. Li, D. Yang Chem. Eng. J. 2010 162 350-354
- (2010) Chem. Eng. J , vol.162 , pp. 350-354
- Hu, S.¹ Wang, A.² Löwe, H.³ Li, X.⁴ Wang, Y.⁵ Li, C.⁶ Yang, D.⁷

33
- 77956651740
- H. Löwe, R. D. Axinte, D. Breuch, C. Hofmann, J. H. Petersen, R. Pommersheim, A. Wang Chem. Eng. J. 2010 163 429-437
- (2010) Chem. Eng. J , vol.163 , pp. 429-437
- Löwe, H.¹ Axinte, R.D.² Breuch, D.³ Hofmann, C.⁴ Petersen, J.H.⁵ Pommersheim, R.⁶ Wang, A.⁷

34
- 81555200715
- N. Ehm, H. Löwe Org. Process Res. Dev. 2011 15 1438-1441
- (2011) Org. Process Res. Dev , vol.15 , pp. 1438-1441
- Ehm, N.¹ Löwe, H.²

35
- 79952313624
- M. N. Kashid, A. Renken, L. Kiwi-Minsker Chem. Eng. Sci. 2011 66 1480-1489
- (2011) Chem. Eng. Sci , vol.66 , pp. 1480-1489
- Kashid, M.N.¹ Renken, A.² Kiwi-Minsker, L.³

36
- 84861621927
- H. Iken, F. Guillen, H. Chaumat, M.-R. Mazières, J.-C. Plaquevent, T. Tzedakis Tetrahedron Lett. 2012 53 3474-3477
- (2012) Tetrahedron Lett , vol.53 , pp. 3474-3477
- Iken, H.¹ Guillen, F.² Chaumat, H.³ Mazières, M.-R.⁴ Plaquevent, J.-C.⁵ Tzedakis, T.⁶

37
- 84862071377
- R. L. Hartman Org. Process Res. Dev. 2012 16 870-887
- (2012) Org. Process Res. Dev , vol.16 , pp. 870-887
- Hartman, R.L.¹

38
- 77953155195
- J. Stoimenovski, D. R. MacFarlane, K. Bica, R. D. Rogers Pharm. Res. 2010 27 521-526
- (2010) Pharm. Res , vol.27 , pp. 521-526
- Stoimenovski, J.¹ Macfarlane, D.R.² Bica, K.³ Rogers, R.D.⁴

39
- 79957610788
- R. Ferraz, L. C. Branco, C. Prudêncio, J. P. Noronha, Z. Petrovski ChemMedChem 2011 6 975-985
- (2011) Chemmedchem , vol.6 , pp. 975-985
- Ferraz, R.¹ Branco, L.C.² Prudêncio, C.³ Noronha, J.P.⁴ Petrovski, Z.⁵

40
- 33847003393
- J. G. Kralj, H. R. Sahoo, K. F. Jensen Lab Chip 2007 7 256-263
- (2007) Lab Chip , vol.7 , pp. 256-263
- Kralj, J.G.¹ Sahoo, H.R.² Jensen, K.F.³

41
- 34547442446
- H. R. Sahoo, J. G. Kralj, K. F. Jensen Angew. Chem., Int. Ed. 2007 46 5704-5708
- (2007) Angew. Chem., Int. Ed , vol.46 , pp. 5704-5708
- Sahoo, H.R.¹ Kralj, J.G.² Jensen, K.F.³

42
- 34547912615
- C. H. Hornung, M. R. Mackley, I. R. Baxendale, S. V. Ley Org. Process Res. Dev. 2007 11 399-405
- (2007) Org. Process Res. Dev , vol.11 , pp. 399-405
- Hornung, C.H.¹ Mackley, M.R.² Baxendale, I.R.³ Ley, S.V.⁴

43
- 75749157029
- R. L. Hartman, J. R. Naber, S. L. Buchwald, K. F. Jensen Angew. Chem., Int. Ed. 2010 49 899-903
- (2010) Angew. Chem., Int. Ed , vol.49 , pp. 899-903
- Hartman, R.L.¹ Naber, J.R.² Buchwald, S.L.³ Jensen, K.F.⁴

44
- 77953141036
- T. Tricotet, D. F. O'Shea Chem.-Eur. J. 2010 16 6678-6686
- (2010) Chem.-Eur. J , vol.16 , pp. 6678-6686
- Tricotet, T.¹ O'shea, D.F.²

45
- 79959283194
- T. Nël, S. Kuhn, A. J. Musacchio, K. F. Jensen, S. L. Buchwald Angew. Chem., Int. Ed. 2011 50 5943-5946
- (2011) Angew. Chem., Int. Ed , vol.50 , pp. 5943-5946
- Nël, T.¹ Kuhn, S.² Musacchio, A.J.³ Jensen, K.F.⁴ Buchwald, S.L.⁵

46
- 84865257966
- M. O'Brien, P. Koos, D. L. Browne, S. V. Ley Org. Biomol. Chem. 2012 10 7031-7036
- (2012) Org. Biomol. Chem , vol.10 , pp. 7031-7036
- O'brien, M.¹ Koos, P.² Browne, D.L.³ Ley, S.V.⁴

47
- 84862086433
- A. E. Cervera-Padrell, S. T. Morthensen, D. J. Lewandowski, T. Skovby, S. Kiil, K. V. Gernaey Org. Process Res. Dev. 2012 16 888-900
- (2012) Org. Process Res. Dev , vol.16 , pp. 888-900
- Cervera-Padrell, A.E.¹ Morthensen, S.T.² Lewandowski, D.J.³ Skovby, T.⁴ Kiil, S.⁵ Gernaey, K.V.⁶

48
- 84876525909
- S. Y. Wong, J. Chen, L. E. Forte, A. S. Myerson Org. Process Res. Dev. 2013 17 684-692
- (2013) Org. Process Res. Dev , vol.17 , pp. 684-692
- Wong, S.Y.¹ Chen, J.² Forte, L.E.³ Myerson, A.S.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.