Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of Profilin-1

Journal of Biological Chemistry

Volumn 290, Issue 14, 2015, Pages 9075-9086

  Diamond, Marc I ^a   Cai, Shirong ^b,c   Boudreau, Aaron ^d   Carey, Clifton J ^b   Lyle, Nicholas ^e   Pappu, Rohit V ^e   Swamidass, S Joshua ^b   Bissell, Mina ^f   Piwnica Worms, Helen ^b,c   Shao, Jieya ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GROWTH; CELL PROLIFERATION; CYTOLOGY; DISEASES; GROWTH KINETICS; MAMMALS; MOBILE SECURITY; PHOSPHORYLATION; PROTEINS; TUMORS;

ACTIN-BINDING PROTEINS; ANTITUMOR MECHANISMS; BREAST CANCER CELLS; NUCLEAR LOCALIZATION; PHOSPHORYLATION SITES; SPATIAL RESTRICTIONS; SUBCELLULAR LOCALIZATIONS; THERAPEUTIC TARGETS;

CELLS;

ACTIN; PROFILIN; PROFILIN 1; SERINE; UNCLASSIFIED DRUG; PFN1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CARTILAGE CELL; CELL CYCLE ARREST; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; TUMOR GROWTH; BREAST TUMOR; CELL FRACTIONATION; CHEMISTRY; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CELL LINE, TUMOR; GENES, TUMOR SUPPRESSOR; HUMANS; PHOSPHORYLATION; PROFILINS; SERINE; SUBCELLULAR FRACTIONS;

EID: 84926442200     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.619874     Document Type: Article

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