-
1
-
-
19644381818
-
Hepatocellular carcinoma: The need for progress
-
Thomas, M. B., Zhu, A. X. Hepatocellular carcinoma: the need for progress. J Clin Oncol. 23, 2892-9 (2005).
-
(2005)
J Clin Oncol.
, vol.23
, pp. 2892-2899
-
-
Thomas, M.B.1
Zhu, A.X.2
-
2
-
-
33947587168
-
Prognostic molecular markers in hepatocellular carcinoma: A systematic review
-
Mann, C. D. et al. Prognostic molecular markers in hepatocellular carcinoma: a systematic review. Eur J Cancer. 43, 979-992 (2007).
-
(2007)
Eur J Cancer.
, vol.43
, pp. 979-992
-
-
Mann, C.D.1
-
3
-
-
33746291023
-
Increased lipogenesis in cancer cells: New players, novel targets
-
Swinnen, J. V., Brusselmans, K., Verhoeven, G. Increased lipogenesis in cancer cells: new players, novel targets. Curr Opin Clin Nutr Metab Care. 9, 358-65 (2006).
-
(2006)
Curr Opin Clin Nutr Metab Care
, vol.9
, pp. 358-365
-
-
Swinnen, J.V.1
Brusselmans, K.2
Verhoeven, G.3
-
4
-
-
12344287240
-
Androgens, lipogenesis and prostate cancer
-
Swinnen, J. V. et al. Androgens, lipogenesis and prostate cancer. J Steroid Biochem Mol Biol. 92, 273-9 (2004).
-
(2004)
J Steroid Biochem Mol Biol
, vol.92
, pp. 273-279
-
-
Swinnen, J.V.1
-
5
-
-
0029829119
-
Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer
-
Shurbaji, M. S., Kalbfleisch, J. H., Thurmond, T. S. Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer. Hum Pathol. 27, 917-21 (1996).
-
(1996)
Hum Pathol
, vol.27
, pp. 917-921
-
-
Shurbaji, M.S.1
Kalbfleisch, J.H.2
Thurmond, T.S.3
-
6
-
-
0034304851
-
Lipid rafts and signal transduction
-
Simons, K., Toomre, D. Lipid rafts and signal transduction. Nat Rev Mol Cell Biol. 1, 31-9 (2000).
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, pp. 31-39
-
-
Simons, K.1
Toomre, D.2
-
7
-
-
84865274702
-
Fatty acid synthase regulates proliferation and migration of colorectal cancer cells via HER2-PI3K/Akt signaling pathway
-
Li, N. et al. Fatty acid synthase regulates proliferation and migration of colorectal cancer cells via HER2-PI3K/Akt signaling pathway. Nutr Cancer. 64, 864-70 (2012).
-
(2012)
Nutr Cancer
, vol.64
, pp. 864-70
-
-
Li, N.1
-
8
-
-
63649099458
-
Fatty acid synthase: A metabolic enzyme and candidate oncogene in prostate cancer
-
Migita, T. et al. Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer. J Natl Cancer Inst. 101, 519-32 (2009).
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 519-532
-
-
Migita, T.1
-
9
-
-
84882605310
-
Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth
-
Lin, R. et al. Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth. Mol Cell. 51, 506-18 (2013).
-
(2013)
Mol Cell.
, vol.51
, pp. 506-518
-
-
Lin, R.1
-
10
-
-
33744808464
-
Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival
-
Chajes, V., Cambot, M., Moreau, K., Lenoir, G. M., Joulin, V. Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival. Cancer Res. 66, 5287-94 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 5287-5294
-
-
Chajes, V.1
Cambot, M.2
Moreau, K.3
Lenoir, G.M.4
Joulin, V.5
-
11
-
-
0034002793
-
Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
-
Kuhajda, F. P. Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition. 16, 202-8 (2000).
-
(2000)
Nutrition
, vol.16
, pp. 202-208
-
-
Kuhajda, F.P.1
-
12
-
-
79952312698
-
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
-
Calvisi, D. F. et al. Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Gastroenterology 140, 1071-1083. e5 (2011).
-
(2011)
Gastroenterology
, vol.140
, pp. 1071-10835
-
-
Calvisi, D.F.1
-
13
-
-
0030063936
-
Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage i breast carcinoma patients
-
Alo, P. L. et al. Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients. Cancer. 77, 474-82 (1996).
-
(1996)
Cancer
, vol.77
, pp. 474-482
-
-
Alo, P.L.1
-
14
-
-
84877143382
-
Fatty acid synthase overexpression confers an independent prognosticator and associates with radiation resistance in nasopharyngeal carcinoma
-
Kao, Y. C. et al. Fatty acid synthase overexpression confers an independent prognosticator and associates with radiation resistance in nasopharyngeal carcinoma. Tumour Biol 34, 759-68 (2013).
-
(2013)
Tumour Biol
, vol.34
, pp. 759-768
-
-
Kao, Y.C.1
-
15
-
-
57449112521
-
Cohort study of fatty acid synthase expression and patient survival in colon cancer
-
Ogino, S. et al. Cohort study of fatty acid synthase expression and patient survival in colon cancer. J Clin Oncol. 26, 5713-20 (2008).
-
(2008)
J Clin Oncol.
, vol.26
, pp. 5713-5720
-
-
Ogino, S.1
-
16
-
-
84863727675
-
Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas
-
Rahman, M. T. et al. Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas. Br J Cancer. 107, 300-7 (2012).
-
(2012)
Br J Cancer.
, vol.107
, pp. 300-307
-
-
Rahman, M.T.1
-
17
-
-
78049433812
-
Increased fatty acid synthase activity in non-small cell lung cancer tissue is a weaker predictor of shorter patient survival than increased lipoprotein lipase activity
-
Cerne, D., Zitnik, I. P.&Sok, M. Increased fatty acid synthase activity in non-small cell lung cancer tissue is a weaker predictor of shorter patient survival than increased lipoprotein lipase activity. Arch Med Res. 41, 405-9 (2010).
-
(2010)
Arch Med Res.
, vol.41
, pp. 405-409
-
-
Cerne, D.1
Zitnik, I.P.2
Sok, M.3
-
18
-
-
84863071066
-
Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer
-
Wang, Y. et al. Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer. Oncol Rep. 27, 1156-62 (2012).
-
(2012)
Oncol Rep.
, vol.27
, pp. 1156-1162
-
-
Wang, Y.1
-
19
-
-
84864858864
-
ATP-citrate lyase: A key player in cancer metabolism
-
Zaidi, N., Swinnen, J. V., Smans, K. ATP-citrate lyase: a key player in cancer metabolism. Cancer Res. 72, 3709-14 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 3709-3714
-
-
Zaidi, N.1
Swinnen, J.V.2
Smans, K.3
-
20
-
-
79955678101
-
The role and impact of SNPs in pharmacogenomics and personalized medicine
-
Laing, R. E., Hess, P., Shen, Y., Wang, J., Hu, S. X. The role and impact of SNPs in pharmacogenomics and personalized medicine. Curr Drug Metab. 12, 460-86 (2011).
-
(2011)
Curr Drug Metab.
, vol.12
, pp. 460-486
-
-
Laing, R.E.1
Hess, P.2
Shen, Y.3
Wang, J.4
Hu, S.X.5
-
21
-
-
84867244386
-
Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata
-
Eggert, S. L. et al. Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata. Am J Hum Genet. 91, 621-8 (2012).
-
(2012)
Am J Hum Genet
, vol.91
, pp. 621-628
-
-
Eggert, S.L.1
-
22
-
-
34047273734
-
Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: A case-control study nested within the European Prospective Investigation into Cancer and Nutrition
-
Sinilnikova, O. M. et al. Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev. 16, 409-15 (2007).
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 409-415
-
-
Sinilnikova, O.M.1
-
23
-
-
10344251473
-
Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility
-
Sinilnikova, O. M. et al. Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility. Carcinogenesis. 25, 2417-24 (2004).
-
(2004)
Carcinogenesis
, vol.25
, pp. 2417-2424
-
-
Sinilnikova, O.M.1
-
24
-
-
77957568227
-
Fatty acid synthase polymorphisms, tumor expression, body mass index, prostate cancer risk, and survival
-
Nguyen, P. L. et al. Fatty acid synthase polymorphisms, tumor expression, body mass index, prostate cancer risk, and survival. J Clin Oncol. 28, 3958-64 (2010).
-
(2010)
J Clin Oncol.
, vol.28
, pp. 3958-3964
-
-
Nguyen, P.L.1
-
25
-
-
79960026089
-
GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis
-
Oxford, England: 1990
-
Xing, J. et al. GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis. Eur J Cancer. (Oxford, England: 1990) 47, 1699-1707 (2011).
-
(2011)
Eur J Cancer
, vol.47
, pp. 1699-1707
-
-
Xing, J.1
-
26
-
-
84856782818
-
Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer
-
Zhou, F. et al. Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer. Cancer. 118, 937-46 (2012).
-
(2012)
Cancer.
, vol.118
, pp. 937-946
-
-
Zhou, F.1
-
28
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan, E. L., Meier, P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 53, 457-481 (1958).
-
(1958)
J Am Stat Assoc.
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
29
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
Menendez, J. A., Lupu, R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer. 7, 763-777 (2007).
-
(2007)
Nat Rev Cancer.
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
30
-
-
0033808261
-
The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung
-
Piyathilake, C. J. et al. The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Hum Pathol. 31, 1068-1073 (2000).
-
(2000)
Hum Pathol.
, vol.31
, pp. 1068-1073
-
-
Piyathilake, C.J.1
-
31
-
-
79952312698
-
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
-
Calvisi, D. F. et al. Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. Gastroenterology. 140, 1071-83 (2011).
-
(2011)
Gastroenterology
, vol.140
, pp. 1071-1083
-
-
Calvisi, D.F.1
-
32
-
-
84865046779
-
Combined Phosphatase and Tensin Homolog (PTEN) Loss and Fatty Acid Synthase (FAS) Overexpression Worsens the Prognosis of Chinese Patients with Hepatocellular Carcinoma
-
Zhu, X. et al. Combined Phosphatase and Tensin Homolog (PTEN) Loss and Fatty Acid Synthase (FAS) Overexpression Worsens the Prognosis of Chinese Patients with Hepatocellular Carcinoma. Int J Mol Sci. 13, 9980-91 (2012).
-
(2012)
Int J Mol Sci.
, vol.13
, pp. 9980-9991
-
-
Zhu, X.1
-
33
-
-
34548814981
-
Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells
-
Yoon, S. et al. Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells. J Biol Chem. 282, 26122-31 (2007).
-
(2007)
J Biol Chem.
, vol.282
, pp. 26122-26131
-
-
Yoon, S.1
-
34
-
-
0030706079
-
Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
-
Milgraum, L. Z., Witters, L. A., Pasternack, G. R., Kuhajda, F. P. Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Clin Cancer Res. 3, 2115-20 (1997).
-
(1997)
Clin Cancer Res.
, vol.3
, pp. 2115-2120
-
-
Milgraum, L.Z.1
Witters, L.A.2
Pasternack, G.R.3
Kuhajda, F.P.4
-
35
-
-
1542748076
-
Aligning multiple genomic sequences with the threaded blockset aligner
-
Blanchette, M. et al. Aligning multiple genomic sequences with the threaded blockset aligner. Genome Res. 14, 708-715 (2004).
-
(2004)
Genome Res.
, vol.14
, pp. 708-715
-
-
Blanchette, M.1
|