Immunomodulatory and antioxidant function of albumin stabilises the endothelium and improves survival in a rodent model of chronic liver failure

Journal of Hepatology

Volumn 62, Issue 4, 2015, Pages 799-806

  Garcia Martinez, Rita ^a   Andreola, Fausto ^a   Mehta, Gautam ^a   Poulton, Katie ^b   Oria, Marc ^a   Jover, Maria ^a   Soeda, Junpei ^a   MacNaughtan, Jane ^a   De Chiara, Francesco ^a   Habtesion, Abeba ^a   Mookerjee, Rajeshwar P ^a   Davies, Nathan ^a   Jalan, Rajiv ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Albumin; Endothelial dysfunction; Human umbilical vein endothelial cells; Liver cirrhosis; Rat

Indexed keywords

ALBUMIN; CELL ADHESION MOLECULE; REACTIVE OXYGEN METABOLITE; ALBUMINOID; ARGININE; N,N-DIMETHYLARGININE; NITRIC OXIDE SYNTHASE; VON WILLEBRAND FACTOR;

ANALBUMINEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRESS; CHRONIC LIVER FAILURE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FUNCTION; MALE; NONHUMAN; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; UMBILICAL VEIN ENDOTHELIAL CELL; ANALOGS AND DERIVATIVES; ANIMAL; DISEASE MODEL; DRUG EFFECTS; END STAGE LIVER DISEASE; HEMODYNAMICS; INFLAMMATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

ALBUMINS; ANIMALS; ARGININE; DISEASE MODELS, ANIMAL; END STAGE LIVER DISEASE; ENDOTHELIUM, VASCULAR; HEMODYNAMICS; HUMANS; INFLAMMATION; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; VON WILLEBRAND FACTOR;

EID: 84926419501     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.10.031     Document Type: Article

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