Metal-free direct N-benzylation of sulfonamides with benzyl alcohols by employing boron trifluoride-diethyl ether complex

Synthesis (Germany)

Volumn 47, Issue 8, 2015, Pages 1101-1108

  Pan, Jing ^a   Li, Jia Qiang ^a   Huang, Ruo Feng ^a   Zhang, Xiao Hui ^a   Shen, Hang ^a   Xiong, Yan ^a   Zhu, Xiang Ming ^b  

^a CHONGQING UNIVERSITY   (China)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

benzyl alcohols; boron tri fluoride diethyl ether complex; N benzylation; sulfonamides; water

Indexed keywords

BORON; ETHERS; SULFUR COMPOUNDS; WATER;

BENZYL ALCOHOL; BORON TRIFLUORIDE; CONTROL EXPERIMENTS; DIETHYL ETHERS; ENVIRONMENTALLY BENIGN; MILD REACTION CONDITIONS; N-BENZYLATION; SULFONAMIDES;

AMIDES;

4 METHYL N (4 METHYLBENZYL)BENZENESULFONAMIDE; BENZYL ALCOHOL; BORON TRIFLUORIDE; ETHER; N (2 IODOBENZYL) 4 METHYLBENZENESULFONAMIDE; N (2,4 DICHLOROBENZYL) 4 METHYLBENZENESULFONAMIDE; N (4 BROMOBENZYL) 4 METHYLBENZENESULFONAMIDE; N (4 CHLOROBENZYL) 4 METHYLBENZENESULFONAMIDE; N (4 FLUOROBENZYL) 4 METHYLBENZENESULFONAMIDE; N BENZHYDRYL 4 METHYLBENZENESULFONAMIDE; N BENZYL 2 METHYLBENZENESULFONAMIDE; N BENZYL 4 BROMOBENZENESULFONAMIDE; N BENZYL 4 METHYLBENZENESULFONAMIDE; N BENZYLBENZENESULFONAMIDE; N BENZYLMETHANESULFONAMIDE; N [1 (3 CHLOROPHENYL)ETHYL] 4 METHYLBENZENESULFONAMIDE; N [1 (3 FLUOROPHENYL)ETHYL] 4 METHYLBENZENESULFONAMIDE; N,N BIS(4 BROMOBENZYL) 4 METHYLBENZENESULFONAMIDE; N,N DIBENZYL 2 METHYLBENZENESULFONAMIDE; N,N DIBENZYL 4 METHYLBENZENESULFONAMIDE; N,N DIBENZYLBENZENESULFONAMIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

ADDITION REACTION; ALKYLATION; ARTICLE; BENZYLATION; CHEMICAL BINDING; COMPLEX FORMATION; CROSS COUPLING REACTION; CYCLIZATION; MOLECULAR INTERACTION; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION TIME; SOLUBILITY; STRUCTURE ANALYSIS;

EID: 84926379755     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0034-1380129     Document Type: Article

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