Exploiting metabolic and antioxidant pathways to maintain vision in blinding disease

Journal of Clinical Investigation

Volumn 125, Issue 4, 2015, Pages 1390-1392

  Ramachandran, Pavitra S ^a   Song, Ji Yun ^a   Bennett, Jean ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CATALASE; GROWTH FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MANGANESE SUPEROXIDE DISMUTASE; PARVOVIRUS VECTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANSCRIPTION FACTOR NRF2; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

AGE RELATED MACULAR DEGENERATION; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CLINICAL EFFECTIVENESS; CLINICAL TRIAL (TOPIC); CONGENITAL BLINDNESS; DISEASE COURSE; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GLAUCOMA; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEALTH CARE COST; HUMAN; LEBER CONGENITAL AMAUROSIS; METABOLISM; NEGATIVE FEEDBACK; NEUROPROTECTION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PATIENT SAFETY; PHOTOPIC VISION; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN SYNTHESIS; QUALITY OF LIFE; RETINA CONE; RETINA DEGENERATION; RETINA ROD; RETINITIS PIGMENTOSA; REVIEW; TRANSGENE; UNFOLDED PROTEIN RESPONSE; UPREGULATION; VISUAL ACUITY; ANIMAL; GENE VECTOR; NERVE CELL; OPTIC NERVE INJURIES; PATHOLOGY; PHYSIOLOGY; THERAPEUTIC USE;

ANIMALS; GENETIC THERAPY; GENETIC VECTORS; MULTIPROTEIN COMPLEXES; NEURONS; NF-E2-RELATED FACTOR 2; OPTIC NERVE INJURIES; OXIDATIVE STRESS; RETINAL CONE PHOTORECEPTOR CELLS; RETINITIS PIGMENTOSA; TOR SERINE-THREONINE KINASES;

EID: 84926363188     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI80821     Document Type: Review

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