Inhibition of type VI secretion by an anti-TssM llama nanobody

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Nguyen, Van Son ^a,b   Logger, Laureen ^c   Spinelli, Silvia ^a,b   Desmyter, Aline ^a,b   Le, Thi Thu Hang ^a,b   Kellenberger, Christine ^a,b   Douzi, Badreddine ^a,b,d   Durand, Eric ^a,b,e   Roussel, Alain ^a,b   Cascales, Eric ^c   Cambillau, Christian ^a,b  

^a CNRS   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c CNRS and Aix Marseille University   (France)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; NANOBODY; NANOBODY NB02; NANOBODY NB25; TSSJ PROTEIN; TSSM PROTEIN; UNCLASSIFIED DRUG; PROTEIN BINDING; TYPE VI SECRETION SYSTEM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; ARTIODACTYLA; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; IN VITRO STUDY; LAMA GLAMA; NONHUMAN; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TYPE VI SECRETION SYSTEM; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; CHEMISTRY; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; NEW WORLD CAMELID; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); CAMELIDAE; EUKARYOTA; LAMA (MAMMAL); NEGIBACTERIA; PROKARYOTA;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; BACTERIAL PROTEINS; CAMELIDS, NEW WORLD; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SINGLE-DOMAIN ANTIBODIES; THERMODYNAMICS; TYPE VI SECRETION SYSTEMS;

EID: 84926344008     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122187     Document Type: Article

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