APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals - A cross-sectional observational study

BMC Neurology

Volumn 15, Issue 1, 2015, Pages

  Cysique, Lucette A ^a,b,c,d   Hewitt, Timothy ^d,e   Croitoru Lamoury, Juliana ^a,d   Taddei, Kevin ^f,g   Martins, Ralph N ^f,g,h   Chew, Constance ⁱ   Davies, Nicholas N W S ^j   Price, Patricia ⁱ   Brew, Bruce J ^a,c,d  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^c ST VINCENT S HOSPITAL   (Australia)

^d St Vincent's Centre for Applied Medical Research   (Australia)

^e UNIVERSITY OF NOTRE DAME   (Australia)

^f EDITH COWAN UNIVERSITY   (Australia)

^g HOLLYWOOD PRIVATE HOSPITAL   (Australia)

^h UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁱ CURTIN UNIVERSITY   (Australia)

^j CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

more..

Author keywords

APOE; A 1 42; CSF; HIV associated neurocognitive disorders; HIV AIDS; p tau; t tau

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; ANTIRETROVIRUS AGENT; APOLIPOPROTEIN E; APOLIPOPROTEIN E4; BIOLOGICAL MARKER; TAU PROTEIN; VIRUS RNA; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ADULT; ALZHEIMER DISEASE; ARTICLE; CD4 LYMPHOCYTE COUNT; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID ANALYSIS; CHRONIC DISEASE; COGNITION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; GLOBAL DEFICIT SCORE; HIV ASSOCIATED DEMENTIA; HOMOZYGOTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LABORATORY TEST; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TEST; OBSERVATIONAL STUDY; PLASMA; PREDICTIVE VALUE; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RECEIVER OPERATING CHARACTERISTIC; RISK FACTOR; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; UNIVARIATE ANALYSIS; AUSTRALIA; GENETICS; PROSPECTIVE STUDY; PSYCHOLOGY; RISK;

AIDS DEMENTIA COMPLEX; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEIN E4; AUSTRALIA; BIOMARKERS; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TESTS; PEPTIDE FRAGMENTS; PROSPECTIVE STUDIES; RISK; SPINAL PUNCTURE; TAU PROTEINS;

EID: 84926341728     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/s12883-015-0298-0     Document Type: Article

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