-
1
-
-
84866985855
-
Targeting the TGFbeta signalling pathway in disease
-
Akhurst R.J., Hata A. Targeting the TGFbeta signalling pathway in disease. Nat. Rev. Drug Discov. 2012, 11:790-811.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 790-811
-
-
Akhurst, R.J.1
Hata, A.2
-
2
-
-
63849130585
-
Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers
-
Alves C.C., et al. Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers. Front. Biosci. (Landmark Ed.) 2009, 14:3035-3050.
-
(2009)
Front. Biosci. (Landmark Ed.)
, vol.14
, pp. 3035-3050
-
-
Alves, C.C.1
-
3
-
-
84869479568
-
Effect of alendronate sodium on the expression of mesenchymal-epithelial transition markers in mice with liver fibrosis
-
Bi W.R., et al. Effect of alendronate sodium on the expression of mesenchymal-epithelial transition markers in mice with liver fibrosis. Exp. Ther. Med. 2013, 5:247-252.
-
(2013)
Exp. Ther. Med.
, vol.5
, pp. 247-252
-
-
Bi, W.R.1
-
4
-
-
79957940895
-
Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin
-
Chang H.Y., et al. Diosgenin suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition by down-regulation of Mdm2 and vimentin. J. Agric. Food Chem. 2011, 59:5357-5363.
-
(2011)
J. Agric. Food Chem.
, vol.59
, pp. 5357-5363
-
-
Chang, H.Y.1
-
5
-
-
84875260698
-
Roles of p38 MAPK and JNK in TGF-β1-induced human alveolar epithelial to mesenchymal transition
-
Chen H.H., et al. Roles of p38 MAPK and JNK in TGF-β1-induced human alveolar epithelial to mesenchymal transition. Arch. Med. Res. 2013, 44:93-98.
-
(2013)
Arch. Med. Res.
, vol.44
, pp. 93-98
-
-
Chen, H.H.1
-
6
-
-
84879682510
-
Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation
-
Chen Y.L., et al. Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation. Cell Death Dis. 2013, 4:e665.
-
(2013)
Cell Death Dis.
, vol.4
, pp. e665
-
-
Chen, Y.L.1
-
7
-
-
35748976970
-
Function of the zinc-finger transcription factor SNAI2 in cancer and development
-
Cobaleda C., et al. Function of the zinc-finger transcription factor SNAI2 in cancer and development. Annu. Rev. Genet. 2007, 41:41-61.
-
(2007)
Annu. Rev. Genet.
, vol.41
, pp. 41-61
-
-
Cobaleda, C.1
-
8
-
-
84897374606
-
Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis
-
Correa-Costa M., et al. Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis. Lab. Investig. 2014, 94:455-466.
-
(2014)
Lab. Investig.
, vol.94
, pp. 455-466
-
-
Correa-Costa, M.1
-
9
-
-
84876015373
-
In vitro toxicity of amorphous silica nanoparticles in human colon carcinoma cells
-
Gehrke H., et al. In vitro toxicity of amorphous silica nanoparticles in human colon carcinoma cells. Nanotoxicology 2013, 7:274-293.
-
(2013)
Nanotoxicology
, vol.7
, pp. 274-293
-
-
Gehrke, H.1
-
10
-
-
84873880140
-
Effects of dexamethasone on the TGF-beta1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells
-
Jang Y.H., et al. Effects of dexamethasone on the TGF-beta1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells. Lab. Investig. 2013, 93:194-206.
-
(2013)
Lab. Investig.
, vol.93
, pp. 194-206
-
-
Jang, Y.H.1
-
11
-
-
61749102618
-
Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis
-
Kim K.K., et al. Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis. J. Clin. Invest. 2009, 119:213-224.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 213-224
-
-
Kim, K.K.1
-
12
-
-
84885453291
-
The differential expression of TGF-β1, ILK and wnt signaling inducing epithelial to mesenchymal transition in human renal fibrogenesis: an immunohistochemical study
-
Kim M.K., et al. The differential expression of TGF-β1, ILK and wnt signaling inducing epithelial to mesenchymal transition in human renal fibrogenesis: an immunohistochemical study. Int. J. Clin. Exp. Pathol. 2013, 6:1747-1758.
-
(2013)
Int. J. Clin. Exp. Pathol.
, vol.6
, pp. 1747-1758
-
-
Kim, M.K.1
-
13
-
-
84871332878
-
Induction of epithelial-mesenchymal transition by flagellin in cultured lung epithelial cells
-
Kondo Y., et al. Induction of epithelial-mesenchymal transition by flagellin in cultured lung epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 2012, 303:L1057-L1069.
-
(2012)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.303
, pp. L1057-L1069
-
-
Kondo, Y.1
-
14
-
-
0033527443
-
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase
-
Kumar S., et al. Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase. Biochem. Biophys. Res. Commun. 1999, 263:825-831.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.263
, pp. 825-831
-
-
Kumar, S.1
-
15
-
-
84882260764
-
Interleukin-22 inhibits bleomycin-induced pulmonary fibrosis
-
Liang M., et al. Interleukin-22 inhibits bleomycin-induced pulmonary fibrosis. Mediat. Inflamm. 2013, 2013:209179.
-
(2013)
Mediat. Inflamm.
, vol.2013
, pp. 209179
-
-
Liang, M.1
-
16
-
-
77950239661
-
BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure
-
Loureiro J., et al. BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure. Nephrol. Dial. Transplant. 2010, 25:1098-1108.
-
(2010)
Nephrol. Dial. Transplant.
, vol.25
, pp. 1098-1108
-
-
Loureiro, J.1
-
17
-
-
79960901978
-
The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells
-
Lv Z.M., et al. The role of the p38 MAPK signaling pathway in high glucose-induced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells. PLoS One 2011, 6:e22806.
-
(2011)
PLoS One
, vol.6
, pp. e22806
-
-
Lv, Z.M.1
-
18
-
-
84866025671
-
Suppression of nanosilica particle-induced inflammation by surface modification of the particles
-
Morishige T., et al. Suppression of nanosilica particle-induced inflammation by surface modification of the particles. Arch. Toxicol. 2012, 86:1297-1307.
-
(2012)
Arch. Toxicol.
, vol.86
, pp. 1297-1307
-
-
Morishige, T.1
-
19
-
-
84895473828
-
Novel therapeutic strategies for fibrotic lung disease: a review with a focus on epithelial-mesenchymal transition
-
Noguchi S., et al. Novel therapeutic strategies for fibrotic lung disease: a review with a focus on epithelial-mesenchymal transition. Recent Patents Inflamm. Allergy Drug Discov. 2014, 8:9-18.
-
(2014)
Recent Patents Inflamm. Allergy Drug Discov.
, vol.8
, pp. 9-18
-
-
Noguchi, S.1
-
20
-
-
4644229397
-
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
-
Palmer H.G., et al. The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat. Med. 2004, 10:917-919.
-
(2004)
Nat. Med.
, vol.10
, pp. 917-919
-
-
Palmer, H.G.1
-
21
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
-
Peinado H., et al. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?. Nat. Rev. Cancer 2007, 7:415-428.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
-
22
-
-
14044276311
-
Basic pathogenetic mechanisms in silicosis: current understanding
-
Rimal B., et al. Basic pathogenetic mechanisms in silicosis: current understanding. Curr. Opin. Pulm. Med. 2005, 11:169-173.
-
(2005)
Curr. Opin. Pulm. Med.
, vol.11
, pp. 169-173
-
-
Rimal, B.1
-
23
-
-
84875646745
-
Gremlin is a downstream profibrotic mediator of transforming growth factor-beta in cultured renal cells
-
Rodrigues-Diez R., et al. Gremlin is a downstream profibrotic mediator of transforming growth factor-beta in cultured renal cells. Nephron Exp. Nephrol. 2012, 122:62-74.
-
(2012)
Nephron Exp. Nephrol.
, vol.122
, pp. 62-74
-
-
Rodrigues-Diez, R.1
-
24
-
-
84886775810
-
All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregulating the TGF-β1/Smad3 signaling pathway in rats
-
Song X., et al. All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregulating the TGF-β1/Smad3 signaling pathway in rats. Lab. Investig. 2013, 93:1219-1231.
-
(2013)
Lab. Investig.
, vol.93
, pp. 1219-1231
-
-
Song, X.1
-
25
-
-
80051740332
-
The role of mitogen-activated protein kinases in crystalline silica-induced cyclooxygenase-2 expression in A549 human lung epithelial cells
-
Tomaru M., Matsuoka M. The role of mitogen-activated protein kinases in crystalline silica-induced cyclooxygenase-2 expression in A549 human lung epithelial cells. Toxicol. Mech. Methods 2011, 21:513-519.
-
(2011)
Toxicol. Mech. Methods
, vol.21
, pp. 513-519
-
-
Tomaru, M.1
Matsuoka, M.2
-
26
-
-
84872197523
-
Smad mediated regulation of inhibitor of DNA binding 2 and its role in phenotypic maintenance of human renal proximal tubule epithelial cells
-
Veerasamy M., et al. Smad mediated regulation of inhibitor of DNA binding 2 and its role in phenotypic maintenance of human renal proximal tubule epithelial cells. PLoS One 2013, 8:e51842.
-
(2013)
PLoS One
, vol.8
, pp. e51842
-
-
Veerasamy, M.1
-
27
-
-
82655174732
-
Protective effect of BMP-7 against aristolochic acid-induced renal tubular epithelial cell injury
-
Wang Z., et al. Protective effect of BMP-7 against aristolochic acid-induced renal tubular epithelial cell injury. Toxicol. Lett. 2010, 198:348-357.
-
(2010)
Toxicol. Lett.
, vol.198
, pp. 348-357
-
-
Wang, Z.1
-
28
-
-
84884805852
-
Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells
-
Wei J., et al. Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells. Cell. Signal. 2013, 25:2788-2796.
-
(2013)
Cell. Signal.
, vol.25
, pp. 2788-2796
-
-
Wei, J.1
-
29
-
-
84891814551
-
Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline
-
Xi Y., et al. Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline. Am. J. Respir. Cell Mol. Biol. 2014, 50:51-60.
-
(2014)
Am. J. Respir. Cell Mol. Biol.
, vol.50
, pp. 51-60
-
-
Xi, Y.1
-
30
-
-
84891942719
-
Epidermal growth factor promotes transforming growth factor-β1-induced epithelial-mesenchymal transition in HK-2 cells through a synergistic effect on Snail
-
Xiong J., et al. Epidermal growth factor promotes transforming growth factor-β1-induced epithelial-mesenchymal transition in HK-2 cells through a synergistic effect on Snail. Mol. Biol. Rep. 2014, 41:241-250.
-
(2014)
Mol. Biol. Rep.
, vol.41
, pp. 241-250
-
-
Xiong, J.1
-
31
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu J., et al. TGF-beta-induced epithelial to mesenchymal transition. Cell Res. 2009, 19:156-172.
-
(2009)
Cell Res.
, vol.19
, pp. 156-172
-
-
Xu, J.1
-
32
-
-
69449084178
-
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition in human renal proximal tubular epithelial cells
-
Xu Y., et al. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition in human renal proximal tubular epithelial cells. J. Nephrol. 2009, 22:403-410.
-
(2009)
J. Nephrol.
, vol.22
, pp. 403-410
-
-
Xu, Y.1
-
33
-
-
84879476665
-
Simvastatin attenuates TGF-beta1-induced epithelial-mesenchymal transition in human alveolar epithelial cells
-
Yang T., et al. Simvastatin attenuates TGF-beta1-induced epithelial-mesenchymal transition in human alveolar epithelial cells. Cell. Physiol. Biochem. 2013, 31:863-874.
-
(2013)
Cell. Physiol. Biochem.
, vol.31
, pp. 863-874
-
-
Yang, T.1
-
34
-
-
0038717407
-
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
Zeisberg M., et al. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat. Med. 2003, 9:964-968.
-
(2003)
Nat. Med.
, vol.9
, pp. 964-968
-
-
Zeisberg, M.1
-
35
-
-
34547676391
-
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
-
Zeisberg E.M., et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat. Med. 2007, 13:952-961.
-
(2007)
Nat. Med.
, vol.13
, pp. 952-961
-
-
Zeisberg, E.M.1
-
36
-
-
34548145815
-
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
-
Zeisberg M., et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J. Biol. Chem. 2007, 282:23337-23347.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23337-23347
-
-
Zeisberg, M.1
-
37
-
-
84883782377
-
Recombinant adeno-associated virus-mediated transfer of shRNA against Notch3 ameliorates hepatic fibrosis in rats
-
Zheng S.P., et al. Recombinant adeno-associated virus-mediated transfer of shRNA against Notch3 ameliorates hepatic fibrosis in rats. Exp. Biol. Med. (Maywood) 2013, 238:600-609.
-
(2013)
Exp. Biol. Med. (Maywood)
, vol.238
, pp. 600-609
-
-
Zheng, S.P.1
|