Ketamine reduces LPS-induced HMGB1 via activation of the Nrf2/HO-1 pathway and NF-κB suppression

Journal of Trauma and Acute Care Surgery

Volumn 78, Issue 4, 2015, Pages 784-792

  Tan, Yonghong ^a   Wang, Qiong ^a   She, Yingjun ^a   Bi, Xiaobao ^a   Zhao, Baisong ^a  

^a GUANGZHOU WOMEN AND CHILDREN S MEDICAL CENTER   (China)

Author keywords

heme oxygenase 1; HMGB1; Ketamine; mice; NF B; sepsis

Indexed keywords

DACTINOMYCIN; HEME OXYGENASE 1; I KAPPA B ALPHA; INTERLEUKIN 1BETA; KETAMINE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROTOPORPHYRIN COBALT; PROTOPORPHYRIN TIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METALLOPORPHYRIN; PROTOPORPHYRIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DNA BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SEPSIS; SIGNAL TRANSDUCTION; TRANSIENT TRANSFECTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CONFOCAL MICROSCOPY; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; MACROPHAGE; METABOLISM; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEME OXYGENASE-1; HMGB1 PROTEIN; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; KETAMINE; LIPOPOLYSACCHARIDES; MACROPHAGES; METALLOPORPHYRINS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE; PHOSPHORYLATION; PROTOPORPHYRINS; REAL-TIME POLYMERASE CHAIN REACTION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84926326964     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000000588     Document Type: Article

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