Scaffold-based cartilage treatments: With or without cells? A systematic review of preclinical and clinical evidence

Arthroscopy - Journal of Arthroscopic and Related Surgery

Volumn 31, Issue 4, 2015, Pages 767-775

  Kon, Elizaveta ^a   Roffi, Alice ^a   Filardo, Giuseppe ^a   Tesei, Giulia ^a   Marcacci, Maurilio ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; HYALURONIC ACID; POLYDIOXANONE; POLYGLYCOLIC ACID; POLYLACTIC ACID;

BONE MARROW; CARTILAGE CELL; CARTILAGE GRAFT; CARTILAGE INJURY; CELL CULTURE; CLINICAL EFFECTIVENESS; CLINICAL STUDY; HUMAN; MATRIX ASSISTED AUTOLOGOUS CHONDROCYTE TRANSPLANTATION; MEDLINE; MESENCHYMAL STEM CELL; MICROFRACTURE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SAFETY; SYSTEMATIC REVIEW; TISSUE ENGINEERING; TISSUE REGENERATION; TISSUE SCAFFOLD; ARTICULAR CARTILAGE; AUTOTRANSPLANTATION; CYTOLOGY; INJURIES; MESENCHYMAL STEM CELL TRANSPLANTATION; PATHOPHYSIOLOGY; TRANSPLANTATION; WOUND HEALING;

CARTILAGE, ARTICULAR; CHONDROCYTES; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; TISSUE SCAFFOLDS; TRANSPLANTATION, AUTOLOGOUS; WOUND HEALING;

EID: 84926294831     PISSN: 07498063     EISSN: 15263231     Source Type: Journal    
DOI: 10.1016/j.arthro.2014.11.017     Document Type: Review

References (34)

1. A. Heijink, A.H. Gomoll, and H. Madry Biomechanical considerations in the pathogenesis of osteoarthritis of the knee Knee Surg Sports Traumatol Arthrosc 20 2012 423 435
2. G. Filardo, E. Kon, A. Roffi, A. Di Martino, and M. Marcacci Scaffold-based repair for cartilage healing: A systematic review and technical note Arthroscopy 29 2013 174 186
3. F. Vannini, G. Filardo, E. Kon, A. Roffi, M. Marcacci, and S. Giannini Scaffolds for cartilage repair of the ankle joint: The impact on surgical practice Foot Ankle Surg 19 2013 2 8
4. H.S. Vasiliadis, B. Danielson, M. Ljungberg, B. McKeon, A. Lindahl, and L. Peterson Autologous chondrocyte implantation in cartilage lesions of the knee: Long-term evaluation with magnetic resonance imaging and delayed gadolinium-enhanced magnetic resonance imaging technique Am J Sports Med 38 2010 943 949
5. M.J. Stoddart, S. Grad, D. Eglin, and M. Alini Cells and biomaterials in cartilage tissue engineering Regen Med 4 2009 81 98
6. E. Kon, G. Filardo, B. Di Matteo, F. Perdisa, and M. Marcacci Matrix assisted autologous chondrocyte transplantation for cartilage treatment: A systematic review Bone Joint Res 2 2013 18 25
7. G. Filardo, E. Kon, A. Di Martino, F. Iacono, and M. Marcacci Arthroscopic second-generation autologous chondrocyte implantation: A prospective 7-year follow-up study Am J Sports Med 39 2011 2153 2160
8. G. Filardo, E. Kon, and M. Berruto Arthroscopic second generation autologous chondrocytes implantation associated with bone grafting for the treatment of knee osteochondritis dissecans: Results at 6 years Knee 19 2012 658 663
9. S. Marlovits, S. Aldrian, and B. Wondrasch Clinical and radiological outcomes 5 years after matrix-induced autologous chondrocyte implantation in patients with symptomatic, traumatic chondral defects Am J Sports Med 40 2012 2273 2280
10. G. Filardo, F. Vannini, and M. Marcacci Matrix-assisted autologous chondrocyte transplantation for cartilage regeneration in osteoarthritic knees: Results and failures at midterm follow-up Am J Sports Med 41 2013 95 100
11. S. Nehrer, R. Dorotka, S. Domayer, D. Stelzeneder, and R. Kotz Treatment of full-thickness chondral defects with hyalograft C in the knee: A prospective clinical case series with 2 to 7 years' follow-up Am J Sports Med 37 2009 81S 87S suppl 1
12. G. Filardo, E. Kon, and F. Perdisa Osteochondral scaffold reconstruction for complex knee lesions: A comparative evaluation Knee 20 2013 570 576
13. E. Kon, G. Filardo, A. Roffi, L. Andriolo, and M. Marcacci New trends for knee cartilage regeneration: From cell-free scaffolds to mesenchymal stem cells Curr Rev Musculoskelet Med 5 2012 236 243
14. G. Filardo, H. Madry, M. Jelic, A. Roffi, M. Cucchiarini, and E. Kon Mesenchymal stem cells for the treatment of cartilage lesions: From preclinical findings to clinical application in orthopaedics Knee Surg Sports Traumatol Arthrosc 21 2013 1717 1729
15. E. Kon, A. Mutini, and E. Arcangeli Novel nanostructured scaffold for osteochondral regeneration: Pilot study in horses J Tissue Eng Regen Med 4 2010 300 308
16. E. Kon, M. Delcogliano, G. Filardo, G. Altadonna, and M. Marcacci Novel nano-composite multi-layered biomaterial for the treatment of multifocal degenerative cartilage lesions Knee Surg Sports Traumatol Arthrosc 17 2009 1312 1315
17. P. Visna, L. Pasa, I. Cizmár, R. Hart, and J. Hoch Treatment of deep cartilage defects of the knee using autologous chondrograft transplantation and by abrasive techniques - A randomized controlled study Acta Chir Belg 104 2004 709 714
18. W. Bartlett, J.A. Skinner, and C.R. Gooding Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: A prospective, randomised study J Bone Joint Surg Br 87 2005 640 645
19. M. Manfredini, F. Zerbinati, A. Gildone, and R. Faccini Autologous chondrocyte implantation: A comparison between an open periosteal-covered and an arthroscopic matrix-guided technique Acta Orthop Belg 73 2007 207 218
20. A. Ferruzzi, R. Buda, and C. Faldini Autologous chondrocyte implantation in the knee joint: Open compared with arthroscopic technique. Comparison at a minimum follow-up of five years J Bone Joint Surg Am 90 2008 90 101 suppl 4
21. E. Kon, A. Gobbi, G. Filardo, M. Delcogliano, S. Zaffagnini, and M. Marcacci Arthroscopic second-generation autologous chondrocyte implantation compared with microfracture for chondral lesions of the knee: Prospective nonrandomized study at 5 years Am J Sports Med 37 2009 33 41
22. E. Basad, B. Ishaque, G. Bachmann, H. Stürz, and J. Steinmeyer Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: A 2-year randomised study Knee Surg Sports Traumatol Arthrosc 18 2010 519 527
23. G.H. Welsch, T.C. Mamisch, and L. Zak Evaluation of cartilage repair tissue after matrix-associated autologous chondrocyte transplantation using a hyaluronic-based or a collagen-based scaffold with morphological MOCART scoring and biochemical T2 mapping: Preliminary results Am J Sports Med 38 2010 934 942
24. F. Zeifang, D. Oberle, C. Nierhoff, W. Richter, B. Moradi, and H. Schmitt Autologous chondrocyte implantation using the original periosteum-cover technique versus matrix-associated autologous chondrocyte implantation: A randomized clinical trial Am J Sports Med 38 2010 924 933
25. B.J. Cole, J. Farr, and C.S. Winalski Outcomes after a single-stage procedure for cell-based cartilage repair: A prospective clinical safety trial with 2-year follow-up Am J Sports Med 39 2011 1170 1179
26. E. Kon, G. Filardo, and M. Berruto Articular cartilage treatment in high-level male soccer players: A prospective comparative study of arthroscopic second-generation autologous chondrocyte implantation versus microfracture Am J Sports Med 39 2011 2549 2557
27. S. Macmull, P.K. Jaiswal, G. Bentley, J.A. Skinner, R.W. Carrington, and T.W. Briggs The role of autologous chondrocyte implantation in the treatment of symptomatic chondromalacia patellae Int Orthop 36 2012 1371 1377
28. A. Panagopoulos, L. van Niekerk, and I. Triantafillopoulos Autologous chondrocyte implantation for knee cartilage injuries: Moderate functional outcome and performance in patients with high-impact activities Orthopedics 35 2012 e6 e14
29. D.C. Crawford, T.M. DeBerardino, and R.J. Williams III NeoCart, an autologous cartilage tissue implant, compared with microfracture for treatment of distal femoral cartilage lesions: An FDA phase-II prospective, randomized clinical trial after two years J Bone Joint Surg Am 94 2012 979 989
30. M. Marcacci, G. Filardo, and E. Kon Treatment of cartilage lesions: What works and why? Injury 44 2013 S11 S15 suppl 1
31. P.C. Kreuz, S. Müller, and U. Freymann Repair of focal cartilage defects with scaffold-assisted autologous chondrocyte grafts: Clinical and biomechanical results 48 months after transplantation Am J Sports Med 39 2011 1697 1705
32. J.M. Patrascu, U. Freymann, C. Kaps, and D.V. Poenaru Repair of a post-traumatic cartilage defect with a cell-free polymer-based cartilage implant: A follow-up at two years by MRI and histological review J Bone Joint Surg Br 92 2010 1160 1163
33. F. Dell'Accio, C. De Bari, and F.P. Luyten Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo Arthritis Rheum 44 2001 1608 1619
34. J. Vanlauwe, D.B. Saris, J. Victor, K.F. Almqvist, J. Bellemans, F.P. Luyten TIG/ACT/01/2000&EXT Study Group Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: Early treatment matters Am J Sports Med 39 2011 2566 2574