High-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats

Hepatology Research

Volumn 45, Issue 4, 2015, Pages 458-469

  Ichimura, Mayuko ^a   Kawase, Miku ^a   Masuzumi, Miki ^a   Sakaki, Mika ^a   Nagata, Yasuo ^a   Tanaka, Kazunari ^a   Suruga, Kazuhito ^a   Tamaru, Shizuka ^a   Kato, Shigeko ^a   Tsuneyama, Koichi ^b   Omagari, Katsuhisa ^a  

^a UNIVERSITY OF NAGASAKI   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Animal model; Enzyme activity; High fat and high cholesterol diet; Liver cirrhosis; Liver fibrosis; Non alcoholic steatohepatitis

Indexed keywords

ABC TRANSPORTER G5; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE SALT EXPORT PUMP; CARNITINE PALMITOYLTRANSFERASE; CD68 ANTIGEN; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; COLLAGEN; DESMIN; FARNESOID X RECEPTOR; FAS ANTIGEN; FATTY ACID SYNTHASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LEPTIN; LIVER ENZYME; LIVER X RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PROCOLLAGEN TYPE 1 ALPHA 1; PROCOLLAGEN TYPE 4 ALPHA 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID SYNTHESIS; BODY WEIGHT; CELL LEVEL; CELL SHAPE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME REPRESSION; EPIDIDYMIS FAT; FATTY ACID OXIDATION; FOOD INTAKE; GENE CONTROL; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIPOLYSIS; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER METABOLISM; LIVER WEIGHT; MALE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; STEATOSIS; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84926218328     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/hepr.12358     Document Type: Article

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