Myocyte-mediated arginase expression controls hyperargininemia but not hyperammonemia in arginase-deficient mice

Molecular Therapy

Volumn 22, Issue 10, 2014, Pages 1792-1802

  Hu, Chuhong ^a   Kasten, Jennifer ^a   Park, Hana ^a   Bhargava, Ragini ^a   Tai, Denise S ^a   Grody, Wayne W ^a   Nguyen, Quynh G ^b   Hauschka, Stephen D ^b   Cederbaum, Stephen D ^a,c   Lipshutz, Gerald S ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; ARGINASE; ARGINASE 1; ARGININE; BETA ACTIN; CITRULLINE; COMPLEMENTARY DNA; CREATINE KINASE; CREATINE KINASE 8; GLUTAMIC ACID; GLUTAMINE; GUANIDINOACETIC ACID; ORNITHINE; PARVOVIRUS VECTOR; THYROXINE BINDING GLOBULIN; UNCLASSIFIED DRUG; CODON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CODON; CONTROLLED STUDY; ENHANCER REGION; EPISOME; FEMALE; GENE EXPRESSION; HEART; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYPERAMMONEMIA; HYPERARGININEMIA; LIVER; LONG TERM SURVIVAL; MALE; MOUSE; MUSCLE CELL; NEWBORN; NONHUMAN; PROMOTER REGION; SKELETAL MUSCLE; TISSUE SPECIFICITY; VIRAL GENE THERAPY; ANIMAL; ANTIBODY SPECIFICITY; CELL LINE; DEPENDOPARVOVIRUS; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; KNOCKOUT MOUSE; LIVER CELL; METABOLISM; MORTALITY; MYOBLAST;

ANIMALIA; MUS;

ANIMALS; ARGINASE; CELL LINE; CODON; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEPATOCYTES; HUMANS; HYPERAMMONEMIA; HYPERARGININEMIA; MALE; MICE; MICE, KNOCKOUT; MUSCLE CELLS; MUSCLE FIBERS, SKELETAL; MYOBLASTS, CARDIAC; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC;

EID: 84926195402     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.99     Document Type: Article

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