Airway mucosal immune-suppression in neonates of mothers receiving a(H1N1)pnd09 vaccination during pregnancy

Pediatric Infectious Disease Journal

Volumn 34, Issue 1, 2015, Pages 84-90

  Bischoff, Anne L ^a   Følsgaard, Nilofar V ^a   Vissing, Nadja H ^a   Birch, Sune ^a   Brix, Susanne ^b   Bisgaard, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Chemokines; Cytokines; Influenza A(H1N1)pnd09; Influenza vaccines; Pregnancy

Indexed keywords

EOTAXIN; EOTAXIN 3; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INFLUENZA VACCINE; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 8; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 4; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ARTICLE; ATOPY; BIRTH; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; IMMUNE STATUS; INFLUENZA A; INFLUENZA VACCINATION; INFLUENZA VIRUS A H1N1; NEWBORN; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEASONAL VARIATION; SECONDARY ANALYSIS; SIBLING; UPPER RESPIRATORY TRACT; UPREGULATION; COHORT ANALYSIS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); MOTHER; NOSE MUCOSA; PROCEDURES; PROSPECTIVE STUDY; RESPIRATORY SYSTEM; RESPIRATORY TRACT INFECTIONS; VACCINATION;

COHORT STUDIES; CYTOKINES; FEMALE; HUMANS; IMMUNE TOLERANCE; INFANT, NEWBORN; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; MOTHERS; NASAL MUCOSA; PREGNANCY; PROSPECTIVE STUDIES; RESPIRATORY SYSTEM; RESPIRATORY TRACT INFECTIONS; VACCINATION;

EID: 84926177363     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0000000000000529     Document Type: Article

References (42)

1. Englund JA. Maternal immunization with inactivated influenza vaccine: rationale and experience. Vaccine. 2003;21:3460-3464.
2. Strategic Advisory Group of Experts on Immunization - report of the extraordinary meeting on the influenza A (H1N1) 2009 pandemic, 7 July 2009. Wkly Epidemiol Rec 2009;84:301-304.
3. Luteijn JM, Dolk H, Marnoch GJ. Differences in pandemic influenza vaccination policies for pregnant women in Europe. BMC Public Health. 2011;11:819.
4. Neuzil KM, Reed GW, Mitchel EF, et al. Impact of influenza on acute cardiopulmonary hospitalizations in pregnant women. Am J Epidemiol. 1998;148:1094-1102.
5. Blanchard-Rohner G, Siegrist CA. Vaccination during pregnancy to protect infants against influenza: why and why not? Vaccine. 2011;29:7542-7550.
6. Skowronski DM, De Serres G. Is routine influenza immunization warranted in early pregnancy? Vaccine. 2009;27:4754-4770.
7. Elderfield R, Barclay W. Influenza Pandemics [Internet]. In: Curtis N, Finn A, Pollard AJ, eds. Hot Topics in Infection and Immunity in Children VIII. New York, NY: Springer; 2011. 81-103. Available from: http://www.springerlink.com/content/11x30kk178u20862/abstract/.
8. Jamieson DJ, Theiler RN, Rasmussen SA. Emerging infections and pregnancy. Emerg Infect Dis. 2006;12:1638-1643.
9. Mosby LG, Rasmussen SA, Jamieson DJ. 2009 pandemic influenza A (H1N1) in pregnancy: a systematic review of the literature. Am J Obstet Gynecol. 2011;205:10-18.
10. The ANZIC Influenza Investigators and Australasian Maternity Outcomes Surveillance System. Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study. BMJ 2010;340:c1279.
11. Siston AM, Rasmussen SA, Honein MA, et al; Pandemic H1N1 Influenza in Pregnancy Working Group. Pandemic 2009 influenza A (H1N1) virus illness among pregnant women in the United States. JAMA. 2010;303:1517-1525.
12. Yates L, Pierce M, Stephens S, et al. Influenza A/H1N1v in pregnancy: an investigation of the characteristics and management of affected women and the relationship to pregnancy outcomes for mother and infant. Health Technol Assess. 2010;14:109-182.
13. Pierce M, Kurinczuk JJ, Spark P, et al; UKOSS. Perinatal outcomes after maternal 2009/H1N1 infection: national cohort study. BMJ. 2011;342:d3214.
14. Libster R, Bugna J, Coviello S, et al. Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina. N Engl J Med. 2010;362:45-55.
15. Munoz FM. Influenza virus infection in infancy and early childhood. Paediatr Respir Rev. 2003;4:99-104.
16. Streng A, Grote V, Liese JG. Severe influenza cases in paediatric intensive care units in Germany during the pre-pandemic seasons 2005 to 2008. BMC Infect Dis. 2011;11:233.
17. Bautista E, Chotpitayasunondh T, Gao Z, et al. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med 2010;362:1708-1719.
18. Groothuis JR, Levin MJ, Rabalais GP, et al. Immunization of high-risk infants younger than 18 months of age with split-product influenza vaccine. Pediatrics. 1991;87:823-828.
19. Piedra PA, Glezen WP, Mbawuike I, et al. Studies on reactogenicity and immunogenicity of attenuated bivalent cold recombinant influenza type A (CRA) and inactivated trivalent influenza virus (TI) vaccines in infants and young children. Vaccine. 1993;11:718-724.
20. Bednarczyk RA, Adjaye-Gbewonyo D, Omer SB. Safety of influenza immunization during pregnancy for the fetus and the neonate. Am J Obstet Gynecol. 2012;207(3 suppl):S38-S46.
21. White PC, Baum DL, Ross H, Falletta L, Reed MD. Cocooning: influenza vaccine for parents and caregivers in an urban, pediatric medical home. Clin Pediatr 2010;49:1123-1128.
22. Walter EB, Allred NJ, Swamy GK, Hellkamp AS, Dolor RJ. Influenza vaccination of household contacts of newborns: a hospital-based strategy to increase vaccination rates. Infect Control Hosp Epidemiol 2010;31:1070-1073.
23. Naleway AL, Smith WJ, Mullooly JP. Delivering influenza vaccine to pregnant women. Epidemiol Rev. 2006;28:47-53.
24. Black SB, Shinefield HR, France EK, et al; Vaccine Safety Datalink Workgroup. Effectiveness of influenza vaccine during pregnancy in preventing hospitalizations and outpatient visits for respiratory illness in pregnant women and their infants. Am J Perinatol. 2004;21:333-339.
25. Chawes BL, Edwards MJ, Shamji B, et al. A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid. J Allergy Clin Immunol. 2010;125:1387-1389.e3.
26. Folsgaard NV, Chawes BL, Rasmussen MA, et al. Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy. Am J Respir Crit Care Med. 2012;185:275-280.
27. Folsgaard NV, Schjorring S, Chawes BL, et al. Pathogenic bacteria colonizing the airways in asymptomatic neonates stimulates topical inflammatory mediator release. Am J Respir Crit Care Med. 2013;187:589-595.
28. Bischoff AL, Folsgaard NV, Carson CG, et al. Altered response to A (H1N1) pnd09 vaccination in pregnant women: a single blinded randomized controlled trial. PLoS One. 2013;8:e56700.
29. Nicholson GC, Kariyawasam HH, Tan AJ, et al. The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge. J Allergy Clin Immunol. 2011;128:800-807.e9.
30. Bisgaard H, Krogsgaard OW, Mygind N. Measurement of secretion in nasal lavage. Clin Sci (Lond). 1987;73:217-222.
31. Pipkorn U, Proud D, Lichtenstein LM, et al. Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticosteroids. N Engl J Med. 1987;316:1506-1510.
32. Marcoe JP, Lim JR, Schaubert KL, et al. TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy. Nat Immunol. 2012;13:843-850.
33. Aluvihare VR, Kallikourdis M, Betz AG. Regulatory T cells mediate maternal tolerance to the fetus. Nat Immunol. 2004;5:266-271.
34. Matson AP, Thrall RS, Rafti E, et al. Breastmilk from allergic mothers can protect offspring from allergic airway inflammation. Breastfeed Med. 2009;4:167-174.
35. Prameela KK. Breastfeeding.anti-viral potential and relevance to the influenza virus pandemic. Med J Malaysia. 2011;66:166-169.
36. Sundqvist M, Osla V, Jacobsson B, et al. Cord blood neutrophils display a galectin-3 responsive phenotype accentuated by vaginal delivery. BMC Pediatr. 2013;13:128.
37. Wang XF, Cao RM, Li J, et al. Identification of sociodemographic and clinical factors associated with the levels of human β-defensin-1 and human β-defensin-2 in the human milk of Han Chinese. Br J Nutr. 2014;111:867-874.
38. Benowitz I, Esposito DB, Gracey KD, et al. Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants. Clin Infect Dis. 2010;51:1355-1361.
39. Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal influenza immunization in mothers and infants. N Engl J Med. 2008;359:1555-1564.
40. Eick AA, Uyeki TM, Klimov A, et al. Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch Pediatr Adolesc Med. 2011;165:104-111.
41. Atladottir HO, Henriksen TB, Schendel DE, et al. Autism after infection, febrile episodes, and antibiotic use during pregnancy: an exploratory study. Pediatrics. 2012;130:e1447-e1454.
42. Abdallah MW, Larsen N, Mortensen EL, et al. Neonatal levels of cytokines and risk of autism spectrum disorders: an exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank. J Neuroimmunol. 2012;252:75-82.