CYP3A4 inhibition by Psoralea corylifolia and its major components in human recombinant enzyme, differentiated human hepatoma HuH-7 and HepaRG cells

Toxicology Reports

Volumn 2, Issue , 2015, Pages 530-534

  Liu, Yitong ^a   Flynn, Thomas J ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

CYP3A4 inhibition; HepaRG cells; Hepatotoxicity; HuH 7 cells; Human recombinant CYP3A4; Isopsoralen; Psoralea corylifolia; Psoralen

Indexed keywords

ANGELICIN; CYTOCHROME P450 3A4; PSORALEA CORYLIFOLIA EXTRACT; PSORALEN; TROLEANDOMYCIN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; FRUIT; HUMAN; HUMAN CELL; IC50; LIVER TOXICITY; LUCIFERASE ASSAY; NONHUMAN; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 84926135961     PISSN: 22147500     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxrep.2015.03.006     Document Type: Article

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