HO-1 attenuates hippocampal neurons injury via the activation of BDNF-TrkB-PI3K/Akt signaling pathway in stroke

Brain Research

Volumn 1577, Issue , 2014, Pages 69-76

  Qi, Dashi ^a   Ouyang, Changjie ^a   Wang, Yulan ^a   Zhang, Shichun ^a   Ma, Xijuan ^b   Song, Yuan Jian ^a   Yu, Hong Li ^a   Tang, Jiali ^c   Fu, Wei ^a   Sheng, Lei ^d   Yang, Lihua ^a   Wang, Mei ^a   Zhang, Weihao ^a   Miao, Lei ^a   Li, Tengteng ^a   Huang, Xiaojing ^a   Dong, Hongyan ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b XUZHOU CENTRAL HOSPITAL   (China)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

^d FUDAN UNIVERSITY   (China)

Author keywords

(BNDF); Apoptosis; Brain derived neurotrophic factor; HO 1; PI3K Akt; Stroke; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; HEME OXYGENASE 1; OLIGONUCLEOTIDE; PROTEIN KINASE B; CARBAZOLE DERIVATIVE; CASP3 PROTEIN, RAT; CASPASE 3; ENZYME INHIBITOR; HEME OXYGENASE; HMOX1 PROTEIN, RAT; INDOLE ALKALOID; PHOSPHATIDYLINOSITOL 3 KINASE; STAUROSPORINE AGLYCONE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ENZYME ACTIVATION; HIPPOCAMPAL CA1 REGION; MALE; NERVE CELL; NERVE CELL DEGENERATION; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA; RATTUS;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CA1 REGION, HIPPOCAMPAL; CARBAZOLES; CASPASE 3; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HEME OXYGENASE (DECYCLIZING); INDOLE ALKALOIDS; MALE; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; SIGNAL TRANSDUCTION; STROKE; TRANSFECTION;

EID: 84925884428     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.06.031     Document Type: Article

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