Calcium/calmodulin-dependent kinase II facilitated GluR6 subunit serine phosphorylation through GluR6-PSD95-CaMKII signaling module assembly in cerebral ischemia injury

Brain Research

Volumn 1366, Issue , 2010, Pages 197-203

  Xu, Jing ^a   Liu, Zhi An ^a,b   Pei, Dong Sheng ^a   Xu, Tie Jun ^a,b  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

CaMKII; Cerebral ischemia; GluR6

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; DIZOCILPINE; GLUTAMATE RECEPTOR 6; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; NIFEDIPINE; POSTSYNAPTIC DENSITY PROTEIN 95; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BENZYLAMINES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; INJECTIONS, INTRAVENTRICULAR; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMBRANE PROTEINS; NIFEDIPINE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, KAINIC ACID; SERINE; SIGNAL TRANSDUCTION; SULFONAMIDES;

EID: 79251605989     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.09.087     Document Type: Article

References (19)

1. A. Barria, V. Derkach, and T. Soderling Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor J. Biol. Chem. 272 52 1997 32727 32730
2. K.U. Bayer Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B J. Neurosci. 26 4 2006 1164 1174
3. I. Bureau Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice J. Neurosci. 19 2 1999 653 663
4. R.J. Colbran Protein phosphatases and calcium/calmodulin-dependent protein kinase II-dependent synaptic plasticity J. Neurosci. 24 39 2004 8404 8409
5. M. Darstein Distribution of kainate receptor subunits at hippocampal mossy fiber synapses J. Neurosci. 23 22 2003 8013 8019
6. R. Dingledine The glutamate receptor ion channels Pharmacol. Rev. 51 1 1999 7 61
7. Z.B. Hao Calcium/calmodulin-dependent protein kinase II (CaMKII), through NMDA receptors and L-Voltage-gated channels, modulates the serine phosphorylation of GluR6 during cerebral ischemia and early reperfusion period in rat hippocampus Brain Res. Mol. Brain Res. 140 1-2 2005 55 62
8. F. Kondo Delayed neuronal death in hippocampal CA1 pyramidal neurons after forebrain ischemia in hyperglycemic gerbils: amelioration by indomethacin Brain Res. 853 1 2000 93 98
9. B.G. Kornreich Identification of C-terminal domain residues involved in protein kinase A-mediated potentiation of kainate receptor subtype 6 Neuroscience 146 3 2007 1158 1168
10. A.L. Mammen Phosphorylation of the alpha-amino-3-hydroxy-5- methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin- dependent kinase II J. Biol. Chem. 272 51 1997 32528 32533
11. R.L. McFeeters, and R.E. Oswald Emerging structural explanations of ionotropic glutamate receptor function FASEB J. 18 3 2004 428 438
12. S. Mehta Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97 J. Biol. Chem. 276 19 2001 16092 16099
13. C. Mulle Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice Nature 392 6676 1998 601 605
14. D.S. Pei Neuroprotective effects of GluR6 antisense oligodeoxynucleotides on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 region J. Neurosci. Res. 82 5 2005 642 649
15. L.A. Raymond, C.D. Blackstone, and R.L. Huganir Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase Nature 361 6413 1993 637 641
16. S. Strack Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A J. Neurochem. 68 5 1997 2119 2128
17. H. Tian Activation of c-Jun NH2-terminal kinase 3 is mediated by the GluR6.PSD-95.MLK3 signaling module following cerebral ischemia in rat hippocampus Brain Res. 1061 1 2005 57 66
18. J.L. Yakel Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors Proc. Natl Acad. Sci. USA 92 5 1995 1376 1380
19. X.B. Yan, B. Song, and G.Y. Zhang Postsynaptic density protein 95 mediates Ca2+/calmodulin-dependent protein kinase II-activated serine phosphorylation of neuronal nitric oxide synthase during brain ischemia in rat hippocampus Neurosci. Lett. 355 3 2004 197 200 (Pubitemid 38368737)