Autophagic signaling and proteolytic enzyme activity in cardiac and skeletal muscle of spontaneously hypertensive rats following chronic aerobic exercise

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  McMillan, Elliott M ^a   Paré, Marie France ^a   Baechler, Brittany L ^a   Graham, Drew A ^a   Rush, James W E ^a   Quadrilatero, Joe ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMPK ALPHA PROTEIN; ATG7 PROTEIN; BECLIN 1; CALPAIN; CASPASE 3; CATHEPSIN; LC3 PROTEIN; LC3I PROTEIN; LC3II PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MESSENGER RNA; MUSCLE PROTEIN; P70S6K PROTEIN; PROTEASOME; PROTEIN KINASE B; PROTEIN P62; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXO3A PROTEIN, RAT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEPTIDE HYDROLASE; S6 KINASE; UBIQUITIN;

AEROBIC EXERCISE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; ENDURANCE TRAINING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; GASTROCNEMIUS MUSCLE; HEART LEFT VENTRICLE; HEART MUSCLE; HYPERTENSION; MALE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; SITTING; SKELETAL MUSCLE; TREADMILL EXERCISE; UBIQUITIN PROTEASOME SYSTEM; ANIMAL; BLOOD PRESSURE; CARDIAC MUSCLE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SPONTANEOUSLY HYPERTENSIVE RAT; TIME FACTOR;

ANIMALIA; RATTUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; BLOOD PRESSURE; FORKHEAD BOX PROTEIN O3; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MUSCLE, SKELETAL; MYOCARDIUM; PEPTIDE HYDROLASES; PHOSPHORYLATION; PHYSICAL CONDITIONING, ANIMAL; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, INBRED SHR; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; UBIQUITIN;

EID: 84925863995     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119382     Document Type: Article

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