Autophagic response to a single bout of moderate exercise in murine skeletal muscle

Journal of Physiology and Biochemistry

Volumn 68, Issue 2, 2012, Pages 229-235

  Kim, Yong An ^a   Kim, Young Sang ^a   Song, Wook ^b  

^a Chungnam National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Autophagy; Single bout of moderate exercise; Skeletal muscle

Indexed keywords

AUTOPHAGY PROTEIN 5; BECLIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2A; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1B LIGHT CHAIN 3; MUSCLE RING FINGER 1 PROTEIN; PROTEIN; PROTEIN AUTOPHAGY RELATED GENE 12; PROTEIN AUTOPHAGY RELATED GENE 7; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CERVICAL SPINE DISLOCATION; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; LIGHT CHAIN; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TREADMILL EXERCISE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; MALE; MICE; MICE, INBRED ICR; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR ACTIVITY; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHYSICAL EXERTION; PROTEIN ISOFORMS; PROTEINS; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; MURINAE; MUS;

EID: 84864033090     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-011-0135-x     Document Type: Article

References (21)

1. Barth S, Glick D, Macleod KF (2010) Autophagy: assays and artifacts. J Pathol 221:117-124
2. Cao Y, Klionsky DJ (2007) Physiological functions of Atg6/ Beclin 1: a unique autophagy-related protein. Cell Res 17:839-849 (Pubitemid 47585112)
3. Cuervo AM (2008) Autophagy and aging: keeping that old broom working. Trends Genet 24:604-612
4. Eskelinen EL, Saftig P (2009) Autophagy: a lysosomal deg-radation pathway with a central role in health and disease. Biochim Biophys Acta 1793:664-673
5. Maiuri MC, Zalckvar E, Kimchi A, Kroemer G (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8:741-752 (Pubitemid 47312826)
6. Masiero E, Sandri M (2010) Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles. Autophagy 6:307-309
7. Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, Metzger D, Reggiani C, Schiaffino S, Sandri M (2009) Autophagy is required to maintain muscle mass. Cell Metab 10:507-515
8. McElhinny AS, Perry CN, Witt CC, Labeit S, Gregorio CC (2004) Muscle-specific RING finger-2 (MURF-2) is impor-tant for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development. J Cell Sci 117:3175-3188 (Pubitemid 39139904)
9. McMullen CA, Ferry AL, Gamboa JL, Andrade FH, Dupont-Versteegden EE (2009) Age-related changes ofcell death pathways in rat extraocular muscle. Exp Gerontol 44:420-425
10. MizushimaN (2009) Physiological functions ofautophagy. Curr Top Microbiol Immunol 335:71-84
11. Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y (2004) In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15:1101-1111 (Pubitemid 38316219)
12. Raben N, Hill V, Shea L, Takikita S, Baum R, Mizushima N, Ralston E, Plotz P (2008) Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease. Hum Mol Genet 17:3897-3908 (Pubitemid 352762852)
13. Rajawat YS, Hilioti Z, Bossis I (2009) Aging: central role for autophagy and the lysosomal degradative system. Ageing Res Rev 8:199-213
14. Salminen A, Kaarniranta K (2009) Regulation of the aging process by autophagy Trends Mol Med 15:217-224
15. Salminen A, Kaarniranta K (2009) SIRT1: regulation of longevity via autophagy. Cell Signal 21:1356-1360
16. Sandri M (2010) Autophagy in skeletal muscle. FEBS Lett 584:1411-1416
17. Vabulas RM, Hartl FU (2005) Protein synthesis upon acute nutrient restriction relies on proteasome function. Science 310:1960-1963 (Pubitemid 43005990)
18. Wang J (2008) Beclin 1 bridges autophagy, apoptosis and differentiation. Autophagy 4:947-948
19. Wohlgemuth SE, Julian D, Akin DE, Fried J, Toscano K, Leeuwenburgh C, Dunn WA Jr (2007) Autophagy in the heart and liver during normal aging and calorie restriction. Rejuvenation Res 10:281-292 (Pubitemid 47378708)
20. Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C (2010) Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol 45:138-148
21. Yen WL, Klionsky DJ (2008) How to live long and prosper: autophagy, mitochondria, and aging. Physiology (Bethesda) 23:248-262