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Volumn 28, Issue 3, 2015, Pages 428-436

Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR 2; TRASTUZUMAB; WNT PROTEIN; ERBB2 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; GPR177 PROTEIN, HUMAN; SIGNAL PEPTIDE;

EID: 84925812252     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2014.114     Document Type: Article
Times cited : (25)

References (59)
  • 1
    • 33646134826 scopus 로고    scopus 로고
    • Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    • Bänziger C, Soldini D, Schü tt C, et al. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 2006;125:509-522
    • (2006) Cell , vol.125 , pp. 509-522
    • Bänziger, C.1    Soldini, D.2    Schütt, C.3
  • 2
    • 33646123992 scopus 로고    scopus 로고
    • Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
    • Bartscherer K, Pelte N, Ingelfinger D, et al. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 2006;125:523-533
    • (2006) Cell , vol.125 , pp. 523-533
    • Bartscherer, K.1    Pelte, N.2    Ingelfinger, D.3
  • 3
    • 37749040775 scopus 로고    scopus 로고
    • The retromer complex influences Wnt secretion by recycling Wntless from endosomes to the trans-golgi network
    • Belenkaya TY, Wu Y, Tang X, et al. The retromer complex influences Wnt secretion by recycling Wntless from endosomes to the trans-golgi network. Dev Cell 2008;14:120-131
    • (2008) Dev Cell , vol.14 , pp. 120-131
    • Belenkaya, T.Y.1    Wu, Y.2    Tang, X.3
  • 4
    • 77956942286 scopus 로고    scopus 로고
    • WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
    • Coombs GS, Yu J, Canning CA, et al. WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification. J Cell Sci 2010;123:3357-3367
    • (2010) J Cell Sci , vol.123 , pp. 3357-3367
    • Coombs, G.S.1    Yu, J.2    Canning, C.A.3
  • 5
    • 84864313614 scopus 로고    scopus 로고
    • A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities
    • Najdi R, Proffitt K, Sprowl S, et al. A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities. Differentiation 2012;84:203-213
    • (2012) Differentiation , vol.84 , pp. 203-213
    • Najdi, R.1    Proffitt, K.2    Sprowl, S.3
  • 6
    • 84855225395 scopus 로고    scopus 로고
    • The Wnt secretion protein Evi/Gpr177 promotes glioma tumorigenesis
    • Augustin I, Goidts V, Bongers A, et al. The Wnt secretion protein Evi/Gpr177 promotes glioma tumorigenesis. EMBO Mol Med 2012;4:38-51
    • (2012) EMBO Mol Med , vol.4 , pp. 38-51
    • Augustin, I.1    Goidts, V.2    Bongers, A.3
  • 7
    • 7944230668 scopus 로고    scopus 로고
    • An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
    • Bafico A, Liu G, Goldin L, et al. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004;6:497-506
    • (2004) Cancer Cell , vol.6 , pp. 497-506
    • Bafico, A.1    Liu, G.2    Goldin, L.3
  • 8
    • 0242361176 scopus 로고    scopus 로고
    • Wnt-signalling pathway in ovarian epithelial tumors: Increased expression of beta-catenin and GSK3beta
    • Rask K, Nilsson A, Brannstrom M, et al. Wnt-signalling pathway in ovarian epithelial tumors: increased expression of beta-catenin and GSK3beta. Br J Cancer 2000;89:1298-1304
    • (2000) Br J Cancer , vol.89 , pp. 1298-1304
    • Rask, K.1    Nilsson, A.2    Brannstrom, M.3
  • 9
    • 62849100998 scopus 로고    scopus 로고
    • Canonical and non canonical Wnt pathway: A comparison among normal ovary, benign ovarian tumor and ovarian cancer
    • Badiglian Filho L, Oshima C, De Oliveira-Lima F, et al. Canonical and non canonical Wnt pathway: a comparison among normal ovary, benign ovarian tumor and ovarian cancer. Oncol Rep 2009;21:313-320
    • (2009) Oncol Rep , vol.21 , pp. 313-320
    • Badiglian Filho, L.1    Oshima, C.2    De Oliveira-Lima, F.3
  • 10
    • 0026948827 scopus 로고
    • Somatic mutation of the APC gene in gastric cancer: Frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma
    • Nakatsuru S, Yanagisawa A, Ichii S, et al. Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma. Hum Mol Genet 1992;1:559-563
    • (1992) Hum Mol Genet , vol.1 , pp. 559-563
    • Nakatsuru, S.1    Yanagisawa, A.2    Ichii, S.3
  • 11
    • 0036193127 scopus 로고    scopus 로고
    • Increased bcatenin mRNA levels and mutational alterations of the APC and b-catenin gene are present in intestinal-type gastric cancer
    • Ebert MPA, Fei G, Kahmann S, et al. Increased bcatenin mRNA levels and mutational alterations of the APC and b-catenin gene are present in intestinal-type gastric cancer. Carcinogenesis 2002;23:87-91
    • (2002) Carcinogenesis , vol.23 , pp. 87-91
    • Ebert, M.P.A.1    Fei, G.2    Kahmann, S.3
  • 12
    • 41549110689 scopus 로고    scopus 로고
    • Mutations in components of the Wnt signaling pathway in gastric cancer
    • Pan K, Liu W, Zhang l, et al. Mutations in components of the Wnt signaling pathway in gastric cancer. World J Gastroentero 2008;14:1570-1574
    • (2008) World J Gastroentero , vol.14 , pp. 1570-1574
    • Pan, K.1    Liu, W.2    Zhang, L.3
  • 13
    • 0034636153 scopus 로고    scopus 로고
    • B-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
    • USA
    • Lin S, Xia W, Wang JC, et al. b-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA 2000;97:4262-4266
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 4262-4266
    • Lin, S.1    Xia, W.2    Wang, J.C.3
  • 14
    • 0033923197 scopus 로고    scopus 로고
    • APC truncation and increased b-catenin levels in a human breast cancer cell line
    • Schlosshauer PW, Brown SA, Eisinger K, et al. APC truncation and increased b-catenin levels in a human breast cancer cell line. Carcinogenesis 2000;21: 1453-1456
    • (2000) Carcinogenesis , vol.21 , pp. 1453-1456
    • Schlosshauer, P.W.1    Brown, S.A.2    Eisinger, K.3
  • 15
    • 0033976526 scopus 로고    scopus 로고
    • Involvement of adenomatous polyposis coli (APC)/b-catenin signalling in human breast cancer
    • Jönsson M, Borg A , Nilbert M, et al. Involvement of adenomatous polyposis coli (APC)/b-catenin signalling in human breast cancer. Eur J Cancer 2000;36: 242-248
    • (2000) Eur J Cancer , vol.36 , pp. 242-248
    • Jönsson, M.1    Borg, A.2    Nilbert, M.3
  • 16
    • 77956945071 scopus 로고    scopus 로고
    • A study of HER2 gene amplification and protein expression in gastric cancer
    • Yan B, Yau EX, Bte Omar SS, et al. A study of HER2 gene amplification and protein expression in gastric cancer. J Clin Pathol 2010;63:839-842
    • (2010) J Clin Pathol , vol.63 , pp. 839-842
    • Yan, B.1    Yau, E.X.2    Bte Omar, S.S.3
  • 17
    • 80052027993 scopus 로고    scopus 로고
    • Sequential expression of putative stem cell markers in gastric carcinogenesis
    • Wang T, Ong CW, Shi J, et al. Sequential expression of putative stem cell markers in gastric carcinogenesis. Br J Cancer 2011;105:658-665
    • (2011) Br J Cancer , vol.105 , pp. 658-665
    • Wang, T.1    Ong, C.W.2    Shi, J.3
  • 18
    • 46749139206 scopus 로고    scopus 로고
    • TRARESA: A tissue microarray-based hospital system for biomarker validation and discovery
    • Das K, Mohd Omar M, Ong C, et al. TRARESA: a tissue microarray-based hospital system for biomarker validation and discovery. Pathology 2008;40:441-449
    • (2008) Pathology , vol.40 , pp. 441-449
    • Das, K.1    Mohd Omar, M.2    Ong, C.3
  • 19
    • 33847746287 scopus 로고    scopus 로고
    • Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumors
    • Salto-Tellez M, Nga ME, Han HC, et al. Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumors. Br J Cancer 2007;96:776-782
    • (2007) Br J Cancer , vol.96 , pp. 776-782
    • Salto-Tellez, M.1    Nga, M.E.2    Han, H.C.3
  • 20
    • 84855357590 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition in malignant mesothelioma
    • Fassina A, Cappellesso R, Guzzardo V, et al. Epithelialmesenchymal transition in malignant mesothelioma. Mod Pathol 2012;25:86-99
    • (2012) Mod Pathol , vol.25 , pp. 86-99
    • Fassina, A.1    Cappellesso, R.2    Guzzardo, V.3
  • 21
    • 80053193164 scopus 로고    scopus 로고
    • Activation of sonic hedgehog signaling in oral squamous cell carcinomas: A preliminary study
    • Cavicchioli Buim ME, Gurgel CAS, Gonçalves Ramos EA, et al. Activation of sonic hedgehog signaling in oral squamous cell carcinomas: a preliminary study. Hum Pathol 2011;42:1484-1490
    • (2011) Hum Pathol , vol.42 , pp. 1484-1490
    • Cavicchioli Buim, M.E.1    Gurgel, C.A.S.2    Gonçalves Ramos, E.A.3
  • 22
    • 84860336909 scopus 로고    scopus 로고
    • Ovarian Carcinomas: Five distinct disease with different origins, genetic alterations and clinicopatholoigcal features
    • Prat J. Ovarian Carcinomas: Five distinct disease with different origins, genetic alterations and clinicopatholoigcal features. Virchows Arch 2012;460:237-249
    • (2012) Virchows Arch , vol.460 , pp. 237-249
    • Prat, J.1
  • 24
    • 3142590865 scopus 로고    scopus 로고
    • Wnt signaling and Breast Cancer
    • Howe L, Brown A. Wnt signaling and Breast Cancer. Cancer Biol Ther 2004;3:36-41
    • (2004) Cancer Biol Ther , vol.3 , pp. 36-41
    • Howe, L.1    Brown, A.2
  • 25
    • 0033609680 scopus 로고    scopus 로고
    • Beta-Catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumors
    • Wright K, Wilson P, Morland S, et al. Beta-Catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumors. Int J Cancer 1999;82:625-629
    • (1999) Int J Cancer , vol.82 , pp. 625-629
    • Wright, K.1    Wilson, P.2    Morland, S.3
  • 26
    • 0038135028 scopus 로고    scopus 로고
    • Loss of beta-catenin expression in metastatic gastric cancer
    • Ebert MPA, Yu J, Hoffmann J, et al. Loss of Beta-Catenin Expression in Metastatic Gastric Cancer. J Clin Oncol 2003;21:1708-1714
    • (2003) J Clin Oncol , vol.21 , pp. 1708-1714
    • Ebert, M.P.A.1    Yu, J.2    Hoffmann, J.3
  • 27
    • 33845541783 scopus 로고    scopus 로고
    • Mutations and nuclear accumulation of Beta-catenin correlate with intestinal phenotypic expression in human gastric cancer
    • Ogasawara N, Tsukamoto T, Mizoshita T, et al. Mutations and nuclear accumulation of Beta-catenin correlate with intestinal phenotypic expression in human gastric cancer. Histopathology 2006;49:612-621
    • (2006) Histopathology , vol.49 , pp. 612-621
    • Ogasawara, N.1    Tsukamoto, T.2    Mizoshita, T.3
  • 29
    • 79251644460 scopus 로고    scopus 로고
    • HER2: Biology, detection and clinical implications
    • Gutierrez C, Schiff R. HER2: biology, detection and clinical implications. Arch Pathol Lab Med 2011;135: 55-62
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 55-62
    • Gutierrez, C.1    Schiff, R.2
  • 30
    • 0024360141 scopus 로고
    • HER-2/neu oncogene protein and prognosis in breast cancer
    • Tandon AK, Clark GM, Chamness GC, et al. HER-2/neu oncogene protein and prognosis in breast cancer. J Clin Oncol 1989;7:1120-1128
    • (1989) J Clin Oncol , vol.7 , pp. 1120-1128
    • Tandon, A.K.1    Clark, G.M.2    Chamness, G.C.3
  • 31
    • 0027436752 scopus 로고
    • Overexpression of c-erbB-2 protein in gastric cancer Its correlation with long-term survival of patients
    • Uchino S, Tsuda H, Maruyama K, et al. Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long-term survival of patients. Cancer 1993;72: 3179-3184
    • (1993) Cancer , vol.72 , pp. 3179-3184
    • Uchino, S.1    Tsuda, H.2    Maruyama, K.3
  • 32
    • 0027219281 scopus 로고
    • Relationship of C-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer
    • Mizutani T, Onda M, Tokunaga A, et al. Relationship of C-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer. Cancer 1993;72:2083-2088
    • (1993) Cancer , vol.72 , pp. 2083-2088
    • Mizutani, T.1    Onda, M.2    Tokunaga, A.3
  • 33
    • 0033135820 scopus 로고    scopus 로고
    • The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas
    • Nakajima M, Sawada H, Yamada Y, et al. The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer 1999;85:1894-1902
    • (1999) Cancer , vol.85 , pp. 1894-1902
    • Nakajima, M.1    Sawada, H.2    Yamada, Y.3
  • 34
    • 84868630658 scopus 로고    scopus 로고
    • HER2 as a prognostic marker in gastric cancer-A systematic analysis of data from the literature
    • Jrgensen J, Hersom M. HER2 as a prognostic marker in gastric cancer-A systematic analysis of data from the literature. J Cancer 2012;3:137-144
    • (2012) J Cancer , vol.3 , pp. 137-144
    • Jrgensen, J.1    Hersom, M.2
  • 35
    • 0025281906 scopus 로고
    • Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer
    • Berchuck A, Kamel A, Whitaker R, et al. Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer. Cancer Res 1990;50:4087-4091
    • (1990) Cancer Res , vol.50 , pp. 4087-4091
    • Berchuck, A.1    Kamel, A.2    Whitaker, R.3
  • 36
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptint) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselga J, Norton L, Albanell J, et al. Recombinant humanized anti-HER2 antibody (Herceptint) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 1998;58:2825-2831
    • (1998) Cancer Res , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3
  • 37
    • 0034638917 scopus 로고    scopus 로고
    • Overexpression of ErbB2 in cancer and ErbB2-targetting strategies
    • Yu D, Hung M. Overexpression of ErbB2 in cancer and ErbB2-targetting strategies. Oncogene 2000;19: 6115-6121
    • (2000) Oncogene , vol.19 , pp. 6115-6121
    • Yu, D.1    Hung, M.2
  • 38
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang Y, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010;376:687-697
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.1    Van Cutsem, E.2    Feyereislova, A.3
  • 39
    • 0037440042 scopus 로고    scopus 로고
    • Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the gynecologic oncology group
    • Bookman MA, Darcy KM, Clarke-Pearson D, et al. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the gynecologic oncology group. J Clin Oncol 2003;21:283-290
    • (2003) J Clin Oncol , vol.21 , pp. 283-290
    • Bookman, M.A.1    Darcy, K.M.2    Clarke-Pearson, D.3
  • 40
    • 52049112530 scopus 로고    scopus 로고
    • A phase i study of lapatinib in combination with carboplatin in women with platinum sensitive recurrent ovarian carcinoma
    • Kimball KJ, Numnum TM, Kirby TO, et al. A phase I study of lapatinib in combination with carboplatin in women with platinum sensitive recurrent ovarian carcinoma. Gynecol Oncol 2008;111:95-101
    • (2008) Gynecol Oncol , vol.111 , pp. 95-101
    • Kimball, K.J.1    Numnum, T.M.2    Kirby, T.O.3
  • 41
    • 84855572685 scopus 로고    scopus 로고
    • A phase I/II study of lapatinib plus carboplatin and paclitaxel in relapsed ovarian and breast cancer
    • Rivkin SE, Muller C, Malmgren JA, et al. A phase I/II study of lapatinib plus carboplatin and paclitaxel in relapsed ovarian and breast cancer. Clinical Ovarian Cancer 2009;2:112-117
    • (2009) Clinical Ovarian Cancer , vol.2 , pp. 112-117
    • Rivkin, S.E.1    Muller, C.2    Malmgren, J.A.3
  • 42
    • 79957697421 scopus 로고    scopus 로고
    • Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma
    • Weroha SJ, Oberg AL, Ziegler KLA, et al. Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma. Gynecol Oncol 2011;122:116-120
    • (2011) Gynecol Oncol , vol.122 , pp. 116-120
    • Weroha, S.J.1    Oberg, A.L.2    Ziegler, K.L.A.3
  • 43
    • 33749003463 scopus 로고    scopus 로고
    • Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: Potential predictive relationship with tumor HER2 activation status
    • Gordon MS, Matei D, Aghajanian C, et al. Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status. J Clin Oncol 2006;24:4324-4332
    • (2006) J Clin Oncol , vol.24 , pp. 4324-4332
    • Gordon, M.S.1    Matei, D.2    Aghajanian, C.3
  • 44
    • 77949900758 scopus 로고    scopus 로고
    • Clinical activity of gemcitabine plus pertuzumab in platinum-resistant ovarian cancer, fallopian tube cancer, or primary peritoneal cancer
    • Makhija S, Amler LC, Glenn D, et al. Clinical activity of gemcitabine plus pertuzumab in platinum-resistant ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. J Clin Oncol 2010;28:1215-1223
    • (2010) J Clin Oncol , vol.28 , pp. 1215-1223
    • Makhija, S.1    Amler, L.C.2    Glenn, D.3
  • 45
    • 74549167752 scopus 로고    scopus 로고
    • Cytoplasmic localization of b-catenin is a marker of poor outcome in breast cancer patients
    • López-Knowles E, Zardawi SJ, McNeil CM, et al. Cytoplasmic localization of b-catenin is a marker of poor outcome in breast cancer patients. Cancer Epidemiol Biomarkers Prev 2010;19:301-309
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 301-309
    • López-Knowles, E.1    Zardawi, S.J.2    McNeil, C.M.3
  • 46
    • 79960050587 scopus 로고    scopus 로고
    • Targeting androgen receptor in estrogen receptor-negative breast cancer
    • Ni M, Chen Y, Lim E, et al. Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell 2011;20:119-131
    • (2011) Cancer Cell , vol.20 , pp. 119-131
    • Ni, M.1    Chen, Y.2    Lim, E.3
  • 47
    • 79551624262 scopus 로고    scopus 로고
    • Beta-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
    • Geyer FC, Lacroix-Triki M, Savage K, et al. Beta-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation. Mod Pathol 2011;24:209-231
    • (2011) Mod Pathol , vol.24 , pp. 209-231
    • Geyer, F.C.1    Lacroix-Triki, M.2    Savage, K.3
  • 48
    • 84863352083 scopus 로고    scopus 로고
    • Activation status of Wnt/-catenin signaling in normal and neoplastic breast tissues: Relationship to HER2/neu expression in human and mouse
    • Khalil S, Tan GA, Giri DD, et al. Activation status of Wnt/-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse. PLoS One 2012;7:33421
    • (2012) PLoS One , vol.7 , pp. 33421
    • Khalil, S.1    Tan, G.A.2    Giri, D.D.3
  • 49
    • 79955754016 scopus 로고    scopus 로고
    • Genomics of the NF-kB signaling pathway: Hypothesized role inovarian cancer
    • White K, Rider D, Kalli KR, et al. Genomics of the NF-kB signaling pathway: hypothesized role inovarian cancer. Cancer Causes Control 2011;22:785-801
    • (2011) Cancer Causes Control , vol.22 , pp. 785-801
    • White, K.1    Rider, D.2    Kalli, K.R.3
  • 50
    • 37749043874 scopus 로고    scopus 로고
    • Wnt signaling requires retromer-dependent recycling of mig-14/wntless in wnt-producing cells
    • Yang P, Lorenowicz MJ, Silhankova M, et al. Wnt Signaling Requires Retromer-Dependent Recycling of MIG-14/Wntless in Wnt-Producing Cells. Dev Cell 2008;14:140-147
    • (2008) Dev Cell , vol.14 , pp. 140-147
    • Yang, P.1    Lorenowicz, M.J.2    Silhankova, M.3
  • 51
    • 79954612742 scopus 로고    scopus 로고
    • The biphasic role of NF-kB in progression and chemoresistance of ovarian cancer
    • Yang G, Xiao X, Rosen DG, et al. The biphasic role of NF-kB in progression and chemoresistance of ovarian cancer. Clin Cancer Res 2011;17:2181-2194
    • (2011) Clin Cancer Res , vol.17 , pp. 2181-2194
    • Yang, G.1    Xiao, X.2    Rosen, D.G.3
  • 52
    • 3242687235 scopus 로고    scopus 로고
    • Inducible nuclear factor-kB activation contributes to chemotherapy resistance in gastric cancer
    • Camp ER, Li J, Minnich DJ, et al. Inducible nuclear factor-kB activation contributes to chemotherapy resistance in gastric cancer. J Am Coll Surg 2004;199:249-258
    • (2004) J Am Coll Surg , vol.199 , pp. 249-258
    • Camp, E.R.1    Li, J.2    Minnich, D.J.3
  • 53
    • 3042716638 scopus 로고    scopus 로고
    • NF-kB activation in human breast cancer specimens and its role in cell proliferation and apoptosis
    • USA
    • Biswas DK, Shi Q, Baily S, et al. NF-kB activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc Natl Acad Sci USA 2004;101:10137-10142
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 10137-10142
    • Biswas, D.K.1    Shi, Q.2    Baily, S.3
  • 54
    • 33846006906 scopus 로고    scopus 로고
    • HER-2 and NF-kB as the targets for therapy-resistant breast cancer
    • Ahmed K, Cao N, Li J. HER-2 and NF-kB as the targets for therapy-resistant breast cancer. Anticancer Res 2006;26:4235-4243
    • (2006) Anticancer Res , vol.26 , pp. 4235-4243
    • Ahmed, K.1    Cao, N.2    Li, J.3
  • 55
    • 77956610796 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • McDermott SP, Wicha MS. Targeting breast cancer stem cells. Mol Oncol 2010;4:404-419
    • (2010) Mol Oncol , vol.4 , pp. 404-419
    • McDermott, S.P.1    Wicha, M.S.2
  • 56
    • 84856435959 scopus 로고    scopus 로고
    • Tjan-Heijnen VCG Taxane resistance in breast cancer: A closed HER2 circuit
    • de Hoon JPJ, Veeck J, BEPJ Vriens, et al. Tjan-Heijnen VCG. Taxane resistance in breast cancer: A closed HER2 circuit? Biochim Biophys Acta 2012;1825:197-206
    • (2012) Biochim Biophys Acta , vol.1825 , pp. 197-206
    • De Hoon, J.P.J.1    Veeck, J.2    Bepj Vriens.3
  • 58
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel CL, Cobleigh MA, Tripathy D, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:719-726
    • (2002) J Clin Oncol , vol.20 , pp. 719-726
    • Vogel, C.L.1    Cobleigh, M.A.2    Tripathy, D.3
  • 59
    • 17144371333 scopus 로고    scopus 로고
    • Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule
    • Baselga J, Carbonell X, Castan eda-Soto N, et al. Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule. J Clin Oncol 2005;23:2162-2171.
    • (2005) J Clin Oncol , vol.23 , pp. 2162-2171
    • Baselga, J.1    Carbonell, X.2    Castan Eda-Soto, N.3


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